Clinical trials: Controlled Diabetes
Diabetes Mellitus, Colo-rectal Cancer
Effectiveness of a Mobile Health Management Program for Colorectal Cancer Survivors With Chronic Conditions
The goal of this clinical trial is to evaluate if a mobile health management program can improve chronic disease management among colorectal cancer survivors with comorbid conditions such as hypertension, diabetes, and…
- Conditions
- Diabetes Mellitus, Colo-rectal Cancer, Hypertension, Dyslipidemia
- Trial name
- NCT06759844
- Testing
- Educational Booklet, Mobile Health Application
- Where
- South Korea
- Volunteers
- 200 people
- Sponsor
- Seoul National University Hospital
Type 2 Diabetes
A Study of TG103 in Subjects With Type 2 Diabetes
The main purpose of this study is to assess the safety and tolerability of multiple ascending doses of TG103 in subjects with type 2 diabetes.
- Trial name
- NCT04790006
- Testing
- TG103
- Volunteers
- 54 people
- Sponsor
- CSPC ZhongQi Pharmaceutical Technology Co., Ltd.
Diabetes Mellitus, Type 2
Single, Ascending Dose, First Time in Human Study for GZR18 in Healthy Subjects
Single ascending dose first time in human study for GZR18 in healthy subjects
- Trial name
- NCT05328726
- Testing
- GZR-18
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Gan and Lee Pharmaceuticals, USA
Pre-diabetes, Pre-hypertension
Primary Prevention of Cardiovascular Disease (CVD) in Pre-diabetic & Pre-hypertensive Subjects
The purpose of this study is to determine whether treating pre-diabetic \& pre-hypertensive individuals using multiple drugs intervention (anti-hypertensive drugs (i.e., ACEI) plus anti-glycemic drug (i.e., metformin) plus…
- Trial name
- PPCVD (NCT01364675)
- Testing
- Metformin+Enalapril+Simvastatin
- Where
- Thailand
- Volunteers
- 8,900 people, healthy volunteers welcome
- Sponsor
- Ramathibodi Hospital
Type 2 Diabetes
The Finnish Diabetes Prevention Study
The aim of this study is to clarify whether lifestyle intervention provided to people with high type 2 diabetes risk will lower the cumulative incidence of diabetes.
- Trial name
- DPS (NCT00518167)
- Testing
- Intensive lifestyle counselling
- Where
- 4 sites in Finland
- Volunteers
- 522 people, healthy volunteers welcome
- Sponsor
- Finnish Institute for Health and Welfare
Diabetes Mellitus, Type 2
Using 32 - Gauge Needles With Lengths of 5 mm and 8 mm on Pain Post-injection, Leak and Blood Glucose
This is a Clinical crossover trial study. In this study, 100 patients with type II diabetes will be selected based on entry and exit criteria, then randomly divided into two equal groups (group "A" and group "B").In the first…
- Trial name
- NCT04460092
- Testing
- 5-mm 32-gauge Insulin needles in the first three days of Intervention, 8-mm 32-gauge Insulin needles in the first three days of Intervention, 5-mm 32-gauge Insulin needles in the last three days of Intervention
- Where
- Iran
- Volunteers
- 100 people
- Sponsor
- Baqiyatallah Medical Sciences University
Hypertension, Diabetes Mellitus, Type 2
Implementation of a Comprehensive Intervention on Hypertension（HTN） and Type 2 Diabetes Mellitus（DM） at PHC Level
Background: The disease burden of hypertension(HTN) and type 2 diabetes mellitus(DM) is rising rapidly in China.Comprehensive interventions(Implementation strategies for providers and interventions for patients) are critical to…
- Trial name
- NCT05353699
- Testing
- Implementation strategies
- Where
- China
- Volunteers
- 12,648 people
- Sponsor
- National Center for Chronic and Noncommunicable Disease Control and Prevention, China CDC
Diabetic Patient (Type 1,2, MODY, Secondary) or With Corticosteroid-induced Diabetes Following Initiation of Corticosteroid Treatment
Tele-expertise in Patients With Diabetes Hospitalized for Covid-19 Infection
Diabetes is a major factor of morbi-mortality in Covid-19 infection. Currently, steroid therapy is required in patients under oxygen therapy. This treatment is associated with hyper glycaemia in patients with diabetes.
- Trial name
- COVIDEX (NCT04726163)
- Testing
- Continuous blind glucose measurement device (Free style Pro)
- Where
- France
- Volunteers
- 48 people
- Sponsor
- University Hospital, Strasbourg, France
Type 2 Diabetes
Renal Effects of DPP-4 Inhibitor Linagliptin in Type 2 Diabetes
The aim of this study is to detail the (mechanisms underlying the) actions of the DPP-4 inhibitor linagliptin on the renal system in patients with type 2 diabetes mellitus.
- Trial name
- RENALIS (NCT02106104)
- Testing
- Linagliptin 5 mg QD (N=24), Glimepiride 1 mg QD (N=24)
- Where
- Netherlands
- Volunteers
- 48 people
- Sponsor
- Amsterdam UMC, location VUmc
Prediabetes
Effects of Dihydroberberine (DHB) on GLP-1, Glycemic Control, Appetite, and Mood in Adults With Pre-Diabetes
The goal of this clinical trial is to learn if Dihydroberberine (DHB) supplementation affects adults with pre-diabetes. The main questions it aims to answer are: Does DHB supplementation increase the concentration of GLP-1 in the…
- Trial name
- DHB (NCT07210684)
- Testing
- Dihydroberberine（DHB）400 mg
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- Nanjing Nutrabuilding Bio-tech Co., Ltd.
Diabetes Mellitus, Type 2
Development of an Information Board and Mobile Application for the Care of Type 2 Diabetes
The SANENT trial is a primary care-based, prospective, two-arm, randomized controlled, open-label, blinded-endpoint study with the aim to compare a diabetes management strategy using an information board and a mobile application…
- Trial name
- SANENT (NCT04974333)
- Testing
- Mobile health application on phone
- Where
- 3 sites in Mexico
- Volunteers
- 1,512 people
- Sponsor
- General Health Council, Mexico
Prediabetes
Continuous Glucose Monitoring (CGM) in Prediabetes With Community Based Recruitment
The objective of this project is to develop a behavioral intervention that combines wearable continuous glucose monitoring (CGM) with smartphone feedback and educational video clips generated by artificial intelligence (AI)…
- Trial name
- G3 (NCT07477249)
- Testing
- CGM
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- David S Black, PhD
Diabetes, Kidney Disease
Improving Outcomes in Patients With Kidney Disease Due to Diabetes
Kidney disease affects about one out of three people with diabetes mellitus, a common medical problem. Treatment of kidney disease with medications that lower blood pressure can slow the kidney disease but there is no known cure.
- Conditions
- Diabetes, Kidney Disease, Hypertension
- Trial name
- NCT00381134
- Testing
- losartan 100 mg orally once daily, spironolactone 25 mg orally once daily
- Where
- United States
- Volunteers
- 92 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Diabetes Mellitus, Type 1
Metabolic Effects of Accurate Blood Sugar Results and Education in Type 1 Diabetes
A randomized controlled trial in patients with type 1 diabetes, assessing the metabolic effects of accurate blood sugar results and education.
- Trial name
- NCT00284232
- Testing
- Use and interpretation of blood glucose results, Insulin dosing based on SMBG chart and education
- Where
- Norway
- Volunteers
- 140 people
- Sponsor
- Helse Stavanger HF
Diabetes
The Effect of Korean Red Ginseng Supplementation on Glucose Control
This study is a randomized, double-blind, placebo-controlled clinical trial designed to evaluate the effect of Korean red ginseng supplementation on glucose control in subjects with impaired fasting glucose, impaired glucose…
- Trial name
- NCT01911663
- Testing
- KRG
- Where
- South Korea
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Diabetes Mellitus
Evaluating Glucose Control Using a Next Generation Automated Insulin Delivery Algorithm in Patients With Type 1 and Type 2 Diabetes
To assess the safety and effectiveness of a next-generation automated insulin delivery algorithm in participants aged 16+ years with type 1 or type 2 diabetes.
- Trial name
- Evolution (NCT06181721)
- Testing
- Omnipod 5 Automated Glucose Control System
- Where
- New Zealand
- Volunteers
- 20 people
- Sponsor
- Insulet Corporation
Diabetic Foot Ulcers
A Clinical Study of the Safety and Efficacy of MEBO Wound Ointment in Subjects With Diabetic Foot Ulcers
The objective of this study is to evaluate the safety and efficacy of MEBO in the treatment of subjects with diabetic foot ulcers (DFUs).
- Trial name
- NCT01070433
- Testing
- MEBO Wound Ointment (MEBO), Standard of Care
- Where
- 9 sites in United States
- Volunteers
- 75 people
- Sponsor
- Skingenix, Inc.
Diabetes Mellitus, Non-Insulin-Dependent
Evaluate the Role of Adding Amaryl to Non-Insulin Dependent Diabetes Mellitus Patients Unresponsive to Maximum Dose Metformin & Thiazolidinedione
The purpose of this study is to assess the efficacy and safety of Amaryl when added to Metformin and Thiazolidinedione (TZD) in non-insulin dependent diabetes mellitus (NIDDM) patients.
- Trial name
- NCT00044447
- Testing
- Glimepiride
- Where
- United States
- Volunteers
- 170 people
- Sponsor
- Sanofi
Insulin Resistance, Menstrual Cycle
Effects of Antipsychotics on Brain Insulin Action in Females
Females treated with antipsychotics have higher rates of comorbid metabolic syndrome than males. Despite this, females have historically been excluded from many mechanistic studies due to confounding effects of menstrual cycles.
- Conditions
- Insulin Resistance, Menstrual Cycle, Type 2 Diabetes, Antipsychotics
- Trial name
- NCT06251635
- Testing
- Olanzapine 2.5Mg Oral Tablet, Insulin Lispro 100 UNT/ML, Saline
- Where
- Canada
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Centre for Addiction and Mental Health
Obesity (Disorder), GLP-1 Receptor Agonist Treatment
Probiotics in Obese Patients Treated With Semaglutide
This randomized, double-blind, placebo-controlled trial evaluated the effects of a four-strain probiotic formulation in adults with obesity receiving semaglutide.
- Conditions
- Obesity (Disorder), GLP-1 Receptor Agonist Treatment, Probiotic Intervention, Diabetes Mellitus Type 2
- Trial name
- ProSem (NCT07847593)
- Testing
- Four-strain probiotic formulation
- Where
- 3 sites in Poland
- Volunteers
- 102 people
- Sponsor
- Nordic Biotic Sp. z o.o.
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