Clinical trials: Controlled Diabetes
Coronary Artery Disease, Diabetes Mellitus
The Effect of Remote Ischemic Preconditioning on Diastolic Function in Coronary Artery Bypass Surgery Between Diabetic and Non-Diabetic Patients
This randomized controlled study aims to evaluate the effects of Remote Ischemic Preconditioning (RIPC) on diastolic function in patients undergoing coronary artery bypass grafting (CABG).
- Conditions
- Coronary Artery Disease, Diabetes Mellitus, Diastolic Function
- Trial name
- NCT06841757
- Testing
- Remote ischemic preconditioning
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Alzahraa Khalil Marie
Oncological Comorbidities (e. g. Hypertension, Diabetes, Malnutrition)
AI-Assisted Comprehensive Management for Cancer Patients With Comorbidities (GCOG-CG001)
Combined with the digital whole process management data pool, a multi-modal data fusion framework is developed, and an AI model is established to realize risk stratification and personalized treatment Recommendation and dynamic…
- Trial name
- GCOG-CG001 (NCT07136727)
- Testing
- AI-assisted comprehensive management system
- Where
- China
- Volunteers
- 5,000 people
- Sponsor
- The First Affiliated Hospital of Xinxiang Medical College
PreDiabetes
Multidisciplinary Care for Lifestyle Change for Metabolic Control and Quality of Life in Prediabetes (PreCPro)
Prediabetes is part of the natural history of type 2 diabetes mellitus, which is one of the main causes of morbidity and mortality in Mexico.
- Trial name
- PreCPro (NCT06468553)
- Testing
- Prediabetes Care Program
- Where
- Mexico
- Volunteers
- 80 people
- Sponsor
- Clinica Especializada en el Manejo de la Diabetes en la Ciudad de Mexico
Diabetic Retinopathy
Lowering Events in Non-proliferative Retinopathy in Scotland
LENS is a streamlined multicentre randomised placebo-controlled parallel-group trial investigating the effect of fenofibrate treatment on the progression of diabetic retinopathy/maculopathy.
- Trial name
- LENS (NCT03439345)
- Testing
- Fenofibrate 145 mg
- Where
- 16 sites in United Kingdom
- Volunteers
- 1,151 people
- Sponsor
- University of Oxford
Diabetes Mellitus
Improving Diabetes Control Through Peer Counseling and Incentives
The specific aims of this study are to test whether in a cohort of low-income minority veterans with poor diabetes mellitus (DM) control: 1. Peer counseling is an effective means of reducing HbA1c (a measure of glucose control).
- Trial name
- NCT01125956
- Testing
- Assigned a peer counselor, Financial incentives
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- University of Pennsylvania
Diabetes Mellitus, Type 2
Efficacy and Safety Study of Empagliflozin as add-on to Insulin in Japanese Patients With Type 2 Diabetes Mellitus
This is a multi-center, randomised, double-blind, placebo-controlled, parallel-group, efficacy and safety study of empagliflozin as add-on to insulin in Japanese patients with Type 2 Diabetes Mellitus with insufficient glycaemic…
- Trial name
- NCT02589639
- Testing
- Empagliflozin
- Where
- 48 sites in Japan
- Volunteers
- 269 people
- Sponsor
- Boehringer Ingelheim
Diabetes Mellitus, Kidney Transplantation
Influence of Pioglitazone for Renal Transplant Function in Diabetics
The purpose of this study is to test whether pioglitazone is able to prevent the progression of diabetic nephropathy in kidney transplant recipients with diabetes mellitus.
- Conditions
- Diabetes Mellitus, Kidney Transplantation, Proteinuria
- Trial name
- NCT00507494
- Testing
- pioglitazone
- Where
- Germany
- Sponsor
- Technische Universität Dresden
Type 2 Diabetes, Overweight
Effects of Caloric Restriction on Fetuin-A and Cardiovascular Risk Factors
The aim of this randomized controlled study was to evaluate the effects of CR on circulating fetuin-A levels in obese humans with type 2 diabetes based on monitoring energy intake and energy expenditure by daily activity.
- Trial name
- NCT01329822
- Testing
- Caloric restriction
- Where
- South Korea
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Korea University
Type 2 Diabetes Mellitus
A Study of ASP1941 in Japanese Patients With Type 2 Diabetes Mellitus
The primary purpose of this study is to evaluate the pharmacodynamic profile (blood glucose and urinary glucose excursion) of ASP1941 in patients with type 2 diabetes mellitus.
- Trial name
- NCT01023945
- Testing
- ASP1941
- Where
- Japan
- Volunteers
- 30 people
- Sponsor
- Astellas Pharma Inc
Diabetes Mellitus, Type 2
A Study to Evaluate the Effectiveness, Safety, and Tolerability of Canagliflozin in Combination With Metformin in the Treatment of Patients With Type 2 Diabetes Mellitus With Inadequate Glycemic Control With Diet and Exercise
The purpose of this study is to assess the effectiveness of the co-administration of canagliflozin and metformin extended release (XR) compared with canagliflozin alone, and metformin XR alone in patients with type 2 diabetes…
- Trial name
- NCT01809327
- Testing
- Canagliflozin 100 mg, Canagliflozin 300 mg, Metformin XR
- Where
- 129 sites in United States, Argentina and 11 more
- Volunteers
- 1,186 people
- Sponsor
- Janssen Research & Development, LLC
Diabetes, Diabetes Mellitus
Glycemic Control in Diabetic Hospitalized Patients
With the advanced management of diabetes and new innovative anti-hyperglycemic therapy hyperglycemia remains a culprit factor affecting the outcome of patients admitted to the hospital in general wards.
- Trial name
- NCT04800861
- Where
- Iraq
- Volunteers
- 120 people
- Sponsor
- AlFayhaa General Hospital
Hypertension, Dyslipidemia
A Novel Digital Tool Clinicians Can Use to Prescribe Exercise to Patients With Cardiovascular Disease Risk Factors
The investigators will conduct a feasibility and pilot efficacy randomized controlled trial to test the usability and user satisfaction of an evidence-based digital health tool the investigators developed for clinicians to use to…
- Conditions
- Hypertension, Dyslipidemia, Diabetes Mellitus, Obesity
- Trial name
- P3-EX (NCT07238556)
- Testing
- Experimental - 12 Week P3-EX Unsupervised Exercise Program with Virtual Weekly Oversight from Graduate Research Assistants, Active Control - 12 Week ACSM-PAVS Unsupervised Exercise Program with Virtual Weekly Oversight from Graduate Research Assistants
- Where
- 3 sites in United States
- Volunteers
- 72 people
- Sponsor
- University of Connecticut
Type 2 Diabetes Mellitus, Peritoneal Dialysis
A Study of Adding Linagliptin to Control Glycemic Variability and HbA1c in Peritoneal Dialysis Patients With Type 2 Diabetes(PDPD) With Premixed Insulin Therapy
In china, there are the most population of type 2 diabetes mellitus (DM) among the world and DM becomes currently the second cause for end-stage renal disease (ESRD).
- Trial name
- NCT03320031
- Testing
- Linagliptin, Humalog Mix 75/25
- Where
- China
- Volunteers
- 232 people
- Sponsor
- Yanbing Li
Type 1 Diabetes Mellitus
Reducing the Risk of Metabolic Decompensation in Diabetic Adolescents by Supervised School Administration of Insulin
This is a pilot study to examine and compare the efficacy of supervised injections of long acting insulins degludec and glargine to protect youth with poorly controlled type 1 diabetes (T1D) from development of ketones.
- Trial name
- NCT03400501
- Testing
- Insulin Degludec, Insulin Glargine
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Yale University
Type 1 Diabetes Mellitus, Cognitive Change
The VRIF Trial: Hypoglycemia Reduction With Automated-Insulin Delivery System
The objective of this pilot study is (i) to test the use of an Artificial Pancreas (AP) System as a viable therapy treatment for two vulnerable populations: 6 to 10 year-old and adults older ≥65 years old with T1D; (ii) to assess…
- Trial name
- NCT03674281
- Testing
- SAP, CLC
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Virginia
Diabetes Mellitus, Type 2
Empagliflozin (BI 10773) Comprehensive add-on Study in Japanese Subjects With Type 2 Diabetes Mellitus
The objective of the study is to investigate the long-term safety and efficacy of BI 10773 given for 52 weeks as add-on therapy to one oral antidiabetic drug in patients with type 2 diabetes mellitus with insufficient glycaemic…
- Trial name
- NCT01368081
- Testing
- Metformin, BI 10773
- Where
- 87 sites in Japan
- Volunteers
- 1,162 people
- Sponsor
- Boehringer Ingelheim
Permanent Neonatal Diabetes Mellitus
Long-Term Sulfonylurea Response in ABCC8 Neonatal Diabetes (SuResponsSUR)
The purpose of this study is to investigate long term response of sulfonylurea and glucose control in children with diabetes due to mutations in ABCC8 that have been switched from insulin injections to sulfonylurea tablets.
- Trial name
- SuResponsSUR (NCT02624830)
- Testing
- Sulfonylurea
- Where
- Norway
- Volunteers
- 30 people
- Sponsor
- Haukeland University Hospital
Type 2 Diabetes Mellitus With Periodontal Complication, Inflammation
Taking Out All Teeth and Replacing Them With Dentures That Rest on Implants in People With Type 2 Diabetes
Gum disease and type 2 diabetes are common chronic diseases that affect each other. Diabetes is increasing, especially in Pakistan. People with diabetes have a greater risk for gum disease.
- Conditions
- Type 2 Diabetes Mellitus With Periodontal Complication, Inflammation, Dental Implant Failed
- Trial name
- NCT01774942
- Testing
- Procedure/Surgery
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- University of Michigan
Gestational Diabetes Mellitus (GDM)
Digital Health Intervention for Early Identification and Prevention of Gestational Diabetes Mellitus
This study aims to develop and evaluate an early risk identification and digital health intervention strategy for gestational diabetes mellitus (GDM) among pregnant women in China.
- Trial name
- NCT07499622
- Testing
- Digital Health Lifestyle Intervention
- Where
- 2 sites in China
- Volunteers
- 1,200 people
- Sponsor
- Peking University
Diabetes, Prediabetes
Meta-analyses of the Effect of Tree Nuts on Glycemic Control and Features of the Metabolic Syndrome
Tree nuts (almonds, Brazil nuts, cashews, hazelnuts, macadamia nuts, pecans, pine nuts, pistachios and walnuts) are an important source of unsaturated fatty acids, vegetable protein, and fibre, as well as minerals, vitamins, and…
- Conditions
- Diabetes, Prediabetes, Dysglycemia, Overweight
- Trial name
- NCT01630980
- Testing
- Tree nuts
- Where
- Canada
- Volunteers
- 1 people
- Sponsor
- John Sievenpiper
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