Clinical trials: Conversational Agent
Hyperglycaemia, Hypertension
Developing an AI Pharmacy Chatbot for the Population of Hong Kong
The primary objective of this study is to is to develop a conversational AI service (chatbot) in Hong Kong to assist patients and caregivers with inquires related to Hospital Authority (HA)-prescribed medications, and to evaluate…
- Conditions
- Hyperglycaemia, Hypertension, Hyperlipidaemia, Artificial Intelligence (AI)
- Trial name
- NCT07037563
- Testing
- An AI pharmacy chatbot offering information related to HA-prescribed medication for hyperglycaemia, hypertension, and hyperlipidaemia
- Where
- 2 sites in Hong Kong
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Adolescent - Emotional Problem, Agent
A Virtual Peer Agent for Counseling Adolescents With Stressful Life Events
This study aims to develop and evaluate a virtual companion agent for providing psychological support to adolescents who have recently experienced stressful life events. This is a single-arm, pre-post pilot trial.
- Conditions
- Adolescent - Emotional Problem, Agent, Psychological, Conversational
- Trial name
- NCT07305064
- Testing
- Virtual Peer Agent Counseling
- Where
- China
- Volunteers
- 55 people
- Sponsor
- Sun Yat-sen University
Literacy, Information Disclosure
ECA vs E-Document Explanation
This study will investigate how consent forms and other health care documents are explained to patients. The findings will be used to create a computer program that can successfully explain consent and other health-related forms…
- Trial name
- NCT03381911
- Testing
- Embodied Conversational Agent
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Boston Medical Center
Preconception Care
Gabby Implementation: Parent Protocol
The Gabby Preconception Care program is an innovative communication system designed to identify and mitigate or resolve health risks for young Black and African American (AA) women before pregnancy, as a means of reducing racial…
- Trial name
- NCT04514224
- Testing
- Gabby implementation, Evaluate the Gabby implementation
- Where
- United States
- Volunteers
- 125 people
- Sponsor
- Boston Medical Center
HIV Infections, Breast Cancer
The MARVIN Chatbots to Provide Information for Different Health Conditions
This research is a continuation of a usability study with the MARVIN chatbot. The investigators aim to adapt the MARVIN chatbot to open it to other health domains (e.g. breast cancer) and populations (e.g. pharmacists).
- Conditions
- HIV Infections, Breast Cancer, Pediatric Emergency Medicine
- Trial name
- NCT05789901
- Testing
- MARVIN, MARVIN-Pharma, MARVINA
- Where
- 2 sites in Canada
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Tobacco Use, Smoking Cessation
Chatbot Counselling for Smoking Cessation in Youths
The goal of this pilot trial is to develop and examine the trial feasibility and acceptability of a chatbot for smoking cessation in youth smokers. Specific aims include: 1.
- Trial name
- NCT06470776
- Testing
- Chatbot counselling, Peer counselling
- Where
- Hong Kong
- Volunteers
- 154 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Opioid Use Disorder, Moderate, Opioid Use Disorder, Severe
A Brief Negotiation Interview Chatbot to Improve Buprenorphine Engagement Among Justice-Involved Individuals
Primary Objective: Conduct pilot study to assess effects of brief negotiation interview (BNI) Chatbot among individuals involved in the Connecticut criminal justice system with opioid use disorder (OUD).
- Conditions
- Opioid Use Disorder, Moderate, Opioid Use Disorder, Severe, Criminal Behavior
- Trial name
- BNICHAT (NCT04982627)
- Testing
- BNI Chatbot, OUD Education & Treatment Resources
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Center for Progressive Recovery, LLC
Influenza, Human, Vaccine Hesitancy
Conversational AI for Adult Flu Vaccination Decisions
This randomized trial tests whether an online guide combining short evidence cards with an AI-guided conversation increases flu-vaccination intention among US adults who haven't decided whether to get a flu vaccine this season.
- Trial name
- NCT07896850
- Testing
- Flu vaccination guide, Accident safety guide
- Where
- United States
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Calypta Systems, Inc.
Eating Behavior, Loneliness
Usage and Health Effects of Embodied Conversational Agents Among Older Adults
Rationale: Embodied Conversational Agents (ECAs), could be a highly effective medium to address health behaviour change among older adults.
- Conditions
- Eating Behavior, Loneliness, Technology Use
- Trial name
- NCT04510883
- Testing
- PACO, Waiting list + PACO
- Where
- Netherlands
- Volunteers
- 52 people
- Sponsor
- Wageningen University and Research
Chatbot-Based Training, Hemodialysis
DialysisBot: AI Chatbot for Hemodialysis Self-Management
End-stage kidney disease requiring hemodialysis is a chronic condition with substantial clinical, functional, and psychosocial burden.
- Conditions
- Chatbot-Based Training, Hemodialysis, Self-management
- Trial name
- NCT07830810
- Testing
- DialysisBot
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- University of Rome Tor Vergata
Diabetes Mellitus Foot Ulcer, Diabetes Mellitus, Type 2
Diabetes Footcare Companion App for Patients and Carers
Diabetes education and self-management support can be delivered via mobile phones. This protocol aims to assess the feasibility and acceptability of Well Feet, a conversational agent, as a diabetic foot care companion.
- Conditions
- Diabetes Mellitus Foot Ulcer, Diabetes Mellitus, Type 2, Diabetic Foot, Diabetic Foot Infection
- Trial name
- NCT05564728
- Testing
- Conversational Agent/Chatbot App
- Where
- 2 sites in Singapore
- Volunteers
- 40 people
- Sponsor
- Nanyang Technological University
Tinnitus
Efficacy and Safety of LLM-Based CBT for Tinnitus
Given the limited evidence on digital cognitive behavioral therapy (CBT) for chronic subjective tinnitus, particularly interventions supported by large language models (LLMs), this two-arm, 30-day randomized controlled trial will…
- Trial name
- NCT07097909
- Testing
- Fudan Tinnitus Doctor (FTD) Conversational AI System, Digital Education Materials
- Where
- China
- Volunteers
- 172 people
- Sponsor
- Eye & ENT Hospital of Fudan University
Mental Health Issue, Anxiety
Clinical Investigation of Wysa
Mental health concerns are a large burden for individuals, healthcare systems, and the economy. Over a million people are referred to UK mental health services each year, but more than half only receive one session of…
- Conditions
- Mental Health Issue, Anxiety, Depressive Symptoms
- Trial name
- NCT05533190
- Testing
- Wysa AI chatbot mental health app
- Where
- 2 sites in United Kingdom
- Volunteers
- 76 people
- Sponsor
- University of Plymouth
History Taking, Artificial Intelligence (AI)
Safety, Feasibility, and Acceptability of the MINERVA Voice Conversational Agent for Emergency Department History-Taking
This study evaluates whether an artificial intelligence (AI) conversational agent called MINERVA (Medical Interface for Navigating the Emergency Room with Voice Assistance) can safely and feasibly gather medical histories from…
- Trial name
- MINERVA-HX (NCT07877883)
- Testing
- MINERVA AI Chatbot
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- Beth Israel Deaconess Medical Center
Smoking Cessation
Mobile Chat Messaging for Smoking Relapse Prevention
Most smokers return to smoking (relapse) after making a quit attempt, but evidence of effective intervention to prevent relapse is scarce.
- Trial name
- NCT05370352
- Testing
- Standard smoking cessation treatment, Personalised chat messaging, SMS text messaging
- Where
- 2 sites in Hong Kong
- Volunteers
- 590 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Patient Satisfaction, Patient Compliance
Study Buddy (an ECA Oncology Trial Advisor) for Cancer Trials
The Study Buddy ECA acts as an advisor to patients on chemotherapy regimens, promoting protocol adherence and retention, providing anticipatory guidance and answering questions, serving as a conduit to capture information about…
- Conditions
- Patient Satisfaction, Patient Compliance, Guideline Adherence
- Trial name
- NCT02742740
- Testing
- Chemo Buddy
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Boston Medical Center
Major Depressive Disorder (MDD)
Evaluating Conversational Artificial Intelligence for Depression Management
The goal of this clinical trial is to evaluate how a conversational method of collecting medical history affects patients' perceptions and experiences compared to clinical care as usual.
- Trial name
- NCT07105397
- Testing
- Conversational AI system vs Usual Care
- Where
- United States
- Volunteers
- 130 people
- Sponsor
- George Mason University
Smoking Cessation
Smoking Cessation Coaching in High-Risk Situations: A Virtual Reality Study
Smoking tobacco is an important preventable risk factor for chronic illnesses and premature death and is most prevalent among groups with a lower socio-economic position (SEP).
- Trial name
- NCT05654545
- Testing
- Lapse prevention dialog: Boost motivation and self-efficacy, Lapse prevention dialog: Future-selves and implementation intentions, Lapse prevention dialog: Identity-related positive self-talk
- Where
- Netherlands
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Leiden University Medical Center
Smoking &Amp; Tobacco Cessation
An Innovative Conversational Agent (Quitbot) for Smoking Cessation
This phase III trial compares two remote digital smoking cessation programs to see how well they work for quitting smoking.
- Trial name
- NCT04308759
- Testing
- Experimental Smoking Cessation Program, Control Smoking Cessation Program
- Where
- United States
- Volunteers
- 1,647 people, healthy volunteers welcome
- Sponsor
- Fred Hutchinson Cancer Center
Nonsuicidal Self Injury, Suicidal Ideation
Digital Mental Health Intervention for Nonsuicidal Self-Injury in Young Adults
This is a feasibility trial of a digital mental health intervention aimed at young adults (ages 18-25) with nonsuicidal self-injury and who are not currently engaged in mental health treatment.
- Conditions
- Nonsuicidal Self Injury, Suicidal Ideation, Depression, Anxiety
- Trial name
- NCT05325944
- Testing
- Self-guided digital intervention for NSSI, Digital intervention for NSSI with coaching, Active control
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Northwestern University