Clinical trials: Conversational Agent
Alcohol Use Disorder
A Feasibility and Acceptability Study of a Large Language Model-based Chatbot for Brief Alcohol Intervention Among Emerging Adults
American emerging adults (EAs; aged 18-29 years) have the highest rates of alcohol use disorder (AUD) and the lowest levels of treatment engagement of any age group.
- Trial name
- NCT07214831
- Testing
- Large language model-based chatbot brief alcohol intervention session
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Massachusetts General Hospital
Eating Disorders
Treatment Uptake Chatbot for Eating Disorders
Eating disorders (EDs) are serious mental illnesses associated with high morbidity and mortality, clinical impairment, and comorbid psychopathology.
- Trial name
- NCT04806165
- Testing
- Repeated Administration, Personalized Recommendation, Motivational Interviewing
- Where
- United States
- Volunteers
- 205 people
- Sponsor
- Washington University School of Medicine
Breast Cancer
Artificial Intelligence vs Physicians for Breast Cancer Patients' Information
Chatbots (contraction of "chat" and "robot") are a computer software program that use statistical learning and aim to simulate a conversation by text or voice message.
- Trial name
- NCT03556813
- Testing
- survey
- Where
- France
- Volunteers
- 150 people
- Sponsor
- Wefight
Loneliness, Social Isolation
A Mechanism Randomised Controlled Trial of a Three-Agent LLM-Augmented mHealth Intervention for Late-Life Loneliness in Older Adults
This study examines how a smartphone conversational application affects feelings of loneliness in Cantonese-speaking older adults living in Hong Kong.
- Conditions
- Loneliness, Social Isolation, Social Isolation in Older Adults
- Trial name
- NCT07822828
- Testing
- Hybrid conversational companion application, Rule-based conversational companion application
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
MCI, Dementia
Tailored Brain Health Insights Through Nurturing Knowledge-based Change - Stakeholder-driven, Human-centered, AI-powered Refinement for Prevention
The goal of this clinical trial is to evaluate whether an AI-powered digital brain health coaching intervention can improve modifiable brain health risk factors in community-dwelling adults aged 40 and above in Singapore.
- Trial name
- THINK-SHARP (NCT07612800)
- Testing
- BLAZE (Brain health Lifestyle Action with personaliZed Engagement)
- Where
- Singapore
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Alexandra Hospital
Tinnitus
Fudan Tinnitus Doctor for Tinnitus Management
The goal of this clinical trial is to evaluate whether a conversational artificial intelligence-based digital intervention can improve symptoms in adults with chronic subjective tinnitus.
- Trial name
- NCT07558837
- Testing
- Fudan Tinnitus Doctor (FTD) System, Non-conversational Digital Education Program
- Where
- China
- Volunteers
- 256 people
- Sponsor
- Eye & ENT Hospital of Fudan University
Breast Carcinoma, Male Breast Carcinoma
Access to Genetic Testing in Underserved Patients With Cancer
This study compares the experiences of people who receive information about genetic testing from a computer-generated character to patients who receive information from a human genetics healthcare provider.
- Conditions
- Breast Carcinoma, Male Breast Carcinoma, Malignant Solid Neoplasm, Metastatic Prostate Carcinoma
- Trial name
- NCT06422455
- Testing
- Best Practice, Educational Intervention, Electronic Health Record Review
- Where
- 2 sites in United States
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Cognitive Therapy, Depression, Postpartum
RCT of Automated Conversational Agent vs. Treatment as Usual for the Management of Perinatal Mood
The purpose of this study is to investigate the efficacy of an evidence-based smartphone application (app) for the management of mood compared to treatment as usual alone among 135 women who have been discharged post-delivery…
- Conditions
- Cognitive Therapy, Depression, Postpartum, Mental Health, Depression
- Trial name
- NCT03646539
- Testing
- Use of smartphone application (app), Treatment as usual
- Where
- United States
- Volunteers
- 201 people, healthy volunteers welcome
- Sponsor
- Stanford University
Work Related Stress, Psychologic Adaptation
CO-ADAPT: Adaptive Environments and Conversational Agent Based Approaches for Healthy Ageing and Work Ability
The purpose of this study is to identify effective methodologies to help people improve their ability to adapt to psychological stress.
- Trial name
- NCT04809090
- Testing
- SMT, App CA
- Where
- Italy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Tommaso Ciulli
Chronic Kidney Disease(CKD)
Virtual Nephrologist
To develop, pilot, and refine a virtual healthcare agent that will educate patients with advanced chronic kidney disease and their caregivers about kidney transplantation.
- Trial name
- vHCA (NCT06841016)
- Testing
- Virtual Nephrologist
- Where
- 2 sites in United States
- Volunteers
- 148 people
- Sponsor
- University of Pennsylvania
Depression, Anxiety
Potency and Precision Investigation
The overarching goal of this study is to establish initial proof of mechanism for precision interventions in an adult population.
- Trial name
- PAPI (NCT06240091)
- Testing
- DISC-MA
- Where
- United States
- Volunteers
- 203 people
- Sponsor
- Woebot Health
Pandemics
Conversational Agent Vaccine Promotion RCT
The objective of this study is to assess the use of and satisfaction with the ECA intervention over a 12-month period, its ability to increase SARS-CoV-2 and influenza vaccination in the BMATP community, and the comparative…
- Trial name
- NCT04884750
- Testing
- ECA-ACE Vaccination Promotion Intervention
- Where
- United States
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Northeastern University
Loneliness, Geriatric Depression
Applying a Chatbot to Geriatric Patients in Psychiatric Clinics: A Pilot Study
This study will use the caring chatbot developed by the Taipei University of Technology team to provide care for participants and use robots to talk to them to collect daily changes in mood, sleep, and activities, and analyze the…
- Trial name
- NCT05054660
- Testing
- caring chatbot
- Volunteers
- 75 people
- Sponsor
- Chang Gung Memorial Hospital
Arthritis, Diabetes
Can Mental Health Chatbots Help Chronic Disease Populations?
Past research has shown that patients suffering from chronic health conditions tend to experience high levels of negative mental health symptoms (e.g., depression).
- Conditions
- Arthritis, Diabetes, Depression, Anxiety
- Trial name
- NCT04620668
- Testing
- Wysa
- Where
- Canada
- Volunteers
- 79 people
- Sponsor
- Luke MacNeill
Mental Disorder, Mental Stress
Virtual Agents-based Digital Interventions to Improve Health
KANOPEE is a free smartphone application providing screening, follow-up tools and autonomous digital interventions to lower psycho-social stress and its repercussions on sleep and behaviors in the general population.
- Conditions
- Mental Disorder, Mental Stress, Insomnia, Depression
- Trial name
- KANOPEE (NCT05074901)
- Testing
- digital behavioral intervention
- Where
- France
- Volunteers
- 20,000 people, healthy volunteers welcome
- Sponsor
- University of Bordeaux