Clinical trials: Conversion
Functional Neurological Symptom Disorder
Eye MOvement DesensItisation and Reprocessing Therapy (EMDR) for FunctIonal Neurological Disorder (FND)
Functional Neurological Disorder (FND) is a problem with the functioning of the nervous system and how the brain and body send and receive signals, rather than due to neurological disease or injury.
- Trial name
- MODIFI (NCT05455450)
- Testing
- Eye movement desensitisation and reprocessing therapy, Neuropsychiatric care
- Where
- 2 sites in United Kingdom
- Volunteers
- 50 people
- Sponsor
- South West London and St George's Mental Health NHS Trust
Renal Transplant, Conversion
Early Pharmacological and Immune Monitoring After Conversion to Belatacept in Renal Transplant Patients
Single-center, prospective, translational, clinical-biological, multidisciplinary study
- Trial name
- EPIMAC-BELA (NCT05632523)
- Testing
- Blood sample, urinary sample
- Where
- France
- Volunteers
- 10 people
- Sponsor
- University Hospital, Tours
Parkinson Disease, Movement Disorder, Functional
The Effects of fNIRS-based Neurofeedback Training on Balance and Gait in Parkinson's Disease
A cross-sectional study (part 1) aims to investigate the influence of fatigue on the MI ability in PD compared to healthy controls.
- Trial name
- NCT05800470
- Testing
- fNIRS-based neurofeedback with motor imagery, Kinesthetic motor imagery, Motor training
- Where
- Taiwan
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- National Yang Ming Chiao Tung University
Biomarkers, MCI Conversion to Dementia
Exploring the Predicting Biomarkers From Mild Cognitive Impairment to Dementia (EBMID)
Mild cognitive impairment (MCI) represents a transitional stage between healthy aging and dementia, and affects more than 15% of the population over the age of 60 in China.
- Trial name
- NCT05697588
- Where
- China
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- Cuibai Wei，Clinical Professor
Functional Neurological Disorder, Functional Movement Disorder
Additive Effects of Interoceptive Training to Physiotherapy in Functional Movement Disorders (interoPTfmd)
Functional movement disorder (FMD) is a common source of neurological disability that imposes a significant financial burden on healthcare systems.
- Trial name
- interoPTfmd (NCT06792760)
- Testing
- Physiotherapy, Specific Breathing Techniques
- Where
- Czechia
- Volunteers
- 80 people
- Sponsor
- Charles University, Czech Republic
Functional Neurological Disorder, Dissociative Seizures
The Feasibility and Acceptability of an Online Yoga Program for People With Functional Neurological Disorders
This is a feasibility study to see if it is acceptable and helpful for people living with a functional neurological disorder to receive online group yoga sessions to improve their wellbeing
- Conditions
- Functional Neurological Disorder, Dissociative Seizures, Psychogenic Seizure, Non-Epileptic Seizure
- Trial name
- YOGA-FUND (NCT07077603)
- Testing
- A12 week, twice weekly, small group, online yoga program
- Volunteers
- 30 people
- Sponsor
- Nottingham University Hospitals NHS Trust
Functional Neurological Disorder, Conversion Disorder
Brain-computer Interface Rehabilitation And Virtual Environments in Functional Neurological Disorder (BRAVE-FND)
The purpose of this study is to determine whether a course of rehabilitation using a device called a brain-computer interface can change the level of control people feel over bodily movements, in functional neurological disorder.
- Conditions
- Functional Neurological Disorder, Conversion Disorder, Functional Neurological Disorders, Conversion Disorder With Weakness/Paralysis
- Trial name
- BRAVE-FND (NCT07006415)
- Testing
- Brain-computer interface rehabilitation
- Volunteers
- 24 people
- Sponsor
- King's College London
Movement Disorders
Neurobiology of Functional Movement Disorder and Non-Epileptic Seizures
This study is part of a series of studies that will explore how the mind and the brain work to cause episodes of uncontrollable shaking in people who have no known underlying brain or medical disorder.
- Trial name
- NCT00500994
- Testing
- MRI
- Where
- 2 sites in United States
- Volunteers
- 254 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Functional Neurological Disorder
The Role of Oxytocin and Interoception in Functional Neurological Disorder
The main goal of this project is to better understand the role of oxytocin and Interoception in FND. More specifically oxytocin's association with precision weighing, prediction errors and priors in the interoceptive domains will…
- Trial name
- NCT06084325
- Testing
- Respiration resistance sensitivity task (RRST), Heartbeat Tracking (HBT), Heartbeat evoked potential (HEP)
- Where
- 2 sites in Switzerland
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- University of Fribourg
Functional Movement Disorder
Study of Sensory Attenuation in Functional Movement Disorders
Functional movement disorders (FMD) are conditions where people experience unusual movements or difficulties with walking, not caused by a specific brain or nerve injury but related to how the brain controls movements.
- Trial name
- NCT06872788
- Where
- Canada
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Western University, Canada
Functional Neurological Symptom Disorder, Neurological Diseases or Conditions
Modulation of Sense of Agency With Non-invasive Brain Stimulation and Mindfulness-based Stress Reduction Therapy
A conversion disorder is a dysfunction of the nervous system in which no structural damage can be demonstrated. However, it must be distinguished from other psychiatric disorders such as psychosis or depression.
- Trial name
- NCT05086380
- Testing
- Mindfulness-based stress reduction therapy, Inhibitory TMS, Psychoeducation
- Where
- Switzerland
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- University of Fribourg
Functional Movement Disorder
Mirror Box Therapy As a Treatment Option for Functional Movement Disorders
The purpose of this study is to investigate the potential of using mirror box therapy as a therapeutic technique amongst patients with functional movement disorders.
- Trial name
- MIMIC (NCT03660098)
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- The Cleveland Clinic
Functional Movement Disorder
Study of the Ability of a New Technique to Effectively Diagnose Movement Disorders
Sante Fe is an investigation of a new technique to distinguish between different types of movement disorders, specifically organic versus functional, by observing changes in involuntary movements in two different situations.
- Trial name
- Sante-Fe (NCT03661021)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- The Cleveland Clinic
Conversion Disorder
Efficacy of Dorso-lateral Prefrontal Cortex Stimulation by tDCS in Motor Conversion Disorder Patients
Conversion disorder refers to impaired voluntary motor or sensory functions that are not compatible with a well-known neurological condition.
- Trial name
- CONVERSTIM (NCT04097184)
- Testing
- Neurostimulation with non-implanted electrodes
- Where
- 8 sites in France
- Volunteers
- 96 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Functional Movement Disorder
Passive Thoughts in Functional Movement Disorders
Passive thoughts also known as mind-wandering are the thoughts that are not produced from the current task. When we aren't focused on a task that needs our full attention, our minds tend to drift from one thought to another.
- Trial name
- NCT06439017
- Testing
- Questionaire
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Western University, Canada
Pain, Traumatic Brain Injury
The NRC Dataset. Developing a Minimum Dataset for Multidisciplinary Rehabilitation: a Modified E-Delphi Study
Several rehabilitation datasets are presently in use for specific patient groups in England. The 'National Clinical Audit of Specialist Rehabilitation for patients with complex needs following major injury' (NCASRI) evaluated…
- Conditions
- Pain, Traumatic Brain Injury, Major Trauma, Multiple Sclerosis
- Trial name
- NCT06726135
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- ThomasCorbett
Mild Traumatic Brain Injury, Functional Neurological Disorder
Rehabilitation for Functional Memory Symptoms After Concussion
This study aims to evaluate the feasibility of novel cognitive behavioural therapy (CBT)-based intervention designed to improve functional memory symptoms after concussion.
- Trial name
- NCT05581810
- Testing
- Cognitive Behavioural Therapy (CBT), Cognitive Rehabilitation
- Where
- 10 sites in Canada
- Volunteers
- 30 people
- Sponsor
- University of British Columbia
Functional Neurological Symptom Disorder, Paralysis
Exploring Functional Paralysis with Advanced Magnetic Resonance Modalities
In functional neurological disorder (FND), neurological symptoms are present, such as paralysis, weakness and disturbed sensation of limbs, although clinically no abnormalities can be found.
- Conditions
- Functional Neurological Symptom Disorder, Paralysis, Conversion Disorder with Weakness/Paralysis
- Trial name
- NCT05139732
- Testing
- Magnetic Resonance Imaging (MRI)
- Where
- Switzerland
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Swiss Paraplegic Research, Nottwil
Functional Neurological Disorder
Body Signal Integration Training: A Case Series
The goal of this clinical trial is to learn about an intervention package in individuals with Functional Neurological Disorder (FND).
- Trial name
- NCT05941702
- Testing
- Body Signal Integration Training
- Where
- United Kingdom
- Volunteers
- 8 people
- Sponsor
- University of Manchester
Intermittent Catheterization, Conversion of Evidence
Conversion of Evidence and Applied Research on Intermittent Catheterization After Radical Hysterectomy
In this study, the investigators summarize the existing best evidence of intermittent catheterization in patients after radical cervical cancer surgery from the perspective of clinical translation of evidence through systematic…
- Trial name
- NCT06529107
- Testing
- intermittent catheterization protocol based on the best evidence
- Where
- China
- Volunteers
- 70 people
- Sponsor
- West China Second University Hospital