Clinical trials: Conversion
Endometrium Cancer
Endometrial Cancer and Robotic-assisted Versus Traditional Laparoscopy
The aim of this study is to compare the robotic-assisted laparoscopic surgery to the traditional laparoscopic surgery in endometrial cancer patients.
- Trial name
- NCT01466777
- Testing
- Traditional surgery type, Robotic assisted laparoscopic surgery
- Where
- Finland
- Volunteers
- 100 people
- Sponsor
- Tampere University Hospital
Functional Neurological Disorder, Functional Movement Disorder
Efficacy of the Multidisciplinary Treatment to the Quality of Life of With Functional Movement Disorders
Randomized-clinical trial of multidisciplinary approach versus psychoeducation in patients with functional movement disorders: impact to their quality of life and their caregivers' quality of life.
- Trial name
- NCT05634486
- Testing
- Multidisciplinary therapeutic approach (physiotherapy plus cognitive-behavioral therapy)
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Fundación Pública Andaluza para la gestión de la Investigación en Sevilla
Ineffective Motility, Diffuse Esophageal Spasms
Reversibility of Dysmotility After Gastric Banding
In the current study we plan to evaluate the effects of the conversion from gastric banding to gastric bypass on esophageal function using combined monitoring.
- Conditions
- Ineffective Motility, Diffuse Esophageal Spasms, Achalasia-Like Dysmotility
- Trial name
- NCT00680030
- Where
- Switzerland
- Volunteers
- 50 people
- Sponsor
- Cantonal Hospital of St. Gallen
Colorectal Adenocarcinoma Metastatic in the Liver
Retlirafusp Alfa Plus Targeted Therapy and Chemotherapy for Unresectable Colorectal Liver-Limited Metastases
This is a single-center, open-label, exploratory phase II trial to evaluate efficacy and safety of Retlirafusp alfa (PD-L1/TGF-βRII bispecific fusion protein) combined with standard first-line targeted-chemotherapy as conversion…
- Trial name
- NCT07815288
- Testing
- Retlirafusp alfa Combined with Targeted Therapy and Chemotherapy
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Peking University Cancer Hospital & Institute
Tourette Syndrome, Tourette's Disorder
Assessment of Children With Tic Onset in the Past 6 Months
The purpose of this research is to study why most children who have tics never develop Tourette syndrome but some do. In other words, we aim to find features that may predict whose tics will go away and whose tics will continue…
- Conditions
- Tourette Syndrome, Tourette's Disorder, Chronic Motor or Vocal Tic Disorder, Transient Tic Disorder
- Trial name
- NewTics (NCT01177774)
- Where
- United States
- Volunteers
- 99 people
- Sponsor
- Washington University School of Medicine
Epilepsy, Functional Neurological Disorder
EXercise-induced PhysioLogical Adaptations In Neurological Disorders
The goal of this study is to investigate how a one-time exercise session influences different parameters of brain function in people with neurological diseases compared to healthy volunteers.
- Conditions
- Epilepsy, Functional Neurological Disorder, Mild Cognitive Impairment, Dementia
- Trial name
- EXPLAIN (NCT07883720)
- Testing
- Acute Exercise
- Where
- United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
EGFR-mutant Non-small Cell Lung Cancer, Potentially Resectable
Neoadjuvant Sacituzumab Tirumotecan and Limertinib for Potentially Resectable Stage Ⅲ EGFR-mutant Non-small Cell Lung Cancer
This study is a prospective, single-arm, exploratory clinical research aimed at evaluating the efficacy and safety of lucetamab in combination with leucovorin in the conversion therapy of locally advanced potentially resectable…
- Trial name
- NCT07323056
- Testing
- Sacituzumab Tirumotecan and Limertinib
- Where
- China
- Volunteers
- 36 people
- Sponsor
- Shanghai Pulmonary Hospital, Shanghai, China
Adrenal Tumor, Adrenal Mass
Prevention of Conversion in Posterior Retroperitoneal Adrenalectomy by Measuring Preoperative Anatomical Conditions
With our retrospective study the investigators show the limitations of the posterior retroperitoneal adrenalectomy by analyzing anatomical parameters.
- Conditions
- Adrenal Tumor, Adrenal Mass, Pheochromocytoma, Conn Adenoma
- Trial name
- NCT04071561
- Testing
- Posterior retroperitoneal adrenalectomy (PRA), Lateral transperitoneal adrenalectomy (LTA)
- Where
- Switzerland
- Volunteers
- 14 people
- Sponsor
- University of Basel
Advanced Hepatocellular Carcinoma (HCC), Prehabilitation
Effect of Prehabilitation During the Conversion Therapy on Postoperative Outcomes in Unresectable Hepatocellular Carcinoma
This is a prospective, randomised controlled clinical trial to study the impact of prehabilitation on postoperative complications, physical function, quality of life, and short-term survival outcomes in patients with unresectable…
- Trial name
- NCT06749678
- Testing
- Prehabilitation, Routine nursing measures
- Where
- China
- Volunteers
- 84 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Globus Sensation
Comparing Pregabalin and Placebo in Patients With Persistent Globus Sensation
To evaluate the relative merits, safety and effectiveness of pregabalin in globus patients compared with placebo.
- Trial name
- Lyrica (NCT05432843)
- Testing
- Pregabalin
- Where
- 2 sites in Belgium
- Volunteers
- 90 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Hepatocellular Carcinoma Non-resectable
Combined TACE, TKI/Anti-VEGF and ICIs as Conversion Therapy for Advanced Hepatocellular Carcinoma
The aim of this study is to the efficacy, prognosis, adverse effects, and factors for predicting therapeutic effects and clinical prognosis of combined therapy of transarterial chemoembolization (TACE), Anti-VEGF antibodies or…
- Trial name
- CCGLC-008 (NCT05717738)
- Testing
- TACE, Lenvatinib, Anti-PD-1 monoclonal antibody
- Where
- 4 sites in China
- Volunteers
- 300 people
- Sponsor
- Tongji Hospital
Functional Movement Disorder, Parkinson Disease
Movement Disorders and Early Maladaptive Schemas
Functional neurological disorders (FND) are neurological symptoms that cannot be explained by a lesion or related to an identified dysfunction of the central nervous system.
- Conditions
- Functional Movement Disorder, Parkinson Disease, Dystonic Disorders
- Trial name
- SCHEMAF (NCT03717376)
- Testing
- Self-questionnaire YSQ-S3 (Young Schema Questionnaire)
- Where
- France
- Volunteers
- 80 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Kidney Transplantation
Study to Compare the Efficacy and Safety After Conversion to RaparoBell® or My-Rept® in Kidney Transplant Patients
The purpose of this study is to evaluate the efficacy and Safety after conversion to RaparoBell® or Myrept® in patients who in renal transplant patients undergoing maintenance therapy with Mycophenolic acid.
- Trial name
- NCT05193565
- Testing
- Sirolimus, Mycophenolate mofetil
- Where
- South Korea
- Volunteers
- 206 people
- Sponsor
- Chong Kun Dang Pharmaceutical
Chronic Hepatitis C-virus Infection, Renal Transplantation
Hepatitis C in Renal Transplant Recipients
The aim of the present trial is to evaluate whether the conversion of immunosuppression from tacrolimus to cyclosporine A induces changes in (i) hepatitis C-virus load, (ii) parameters of hepatic function and (iii) parameters of…
- Trial name
- NCT02108301
- Testing
- tacrolimus-cyclosporine A
- Where
- Austria
- Volunteers
- 30 people
- Sponsor
- Prof. Dr. Alice Schmidt
Parkinson Disease
Pramipexole Conversion to Ropinirole Controlled Release (CR)
A conversion study of Mirapex (pramipexole) to Requip (ropinirole) controlled release (CR) in patients with Parkinson's disease to determine the appropriate conversion ratio and side effects related to the drug.
- Trial name
- NCT00275275
- Testing
- Requip PR, Mirapex
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- Rajesh Pahwa, MD
Kidney Transplant; Complications, CMV
CMVIG Prophylaxis in Belatacept Conversion Kidney Transplant Recipients
The purpose of this study is to study how CMVIG interacts with the body and to see if it might work to prevent kidney transplant patients from becoming infected with CMV.
- Trial name
- NCT07096453
- Testing
- Cytogam
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Minnesota
Pulmonary Tuberculosis
Efficacy of Oral Zinc Administration as an Adjunct Therapy in New Pulmonary Tuberculosis (Category I) Patients
The primary objective of the study is to evaluate the efficacy of oral Zinc administration in new smear positive pulmonary tuberculosis patients.
- Trial name
- NCT00698386
- Testing
- Zinc supplement
- Where
- India
- Volunteers
- 150 people
- Sponsor
- Ministry of Science and Technology, India
Fear, Movement Disorder, Functional
Surgery and Functionality in Older Adults
When the literature is examined, it has not been found that the use of massage applications in relation to the functional level of individuals who have undergone abdominal surgery.
- Conditions
- Fear, Movement Disorder, Functional, Kinesiophobia, Surgery
- Trial name
- SFO (NCT05534490)
- Testing
- therapatic Foot massaje (sweden technic)
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- University of Yalova
Kidney Transplant Rejection, Gastrointestinal Disorder, Functional
Conversion From MPA to Zortress (Everolimus) for GI Toxicity Post-renal Transplantation
Patients who receive renal transplantation at Barnes Jewish Hospital (BJH) are placed on triple maintenance immunosuppression, which means that patients take 3 types of immunosuppression drugs to suppress their immune system…
- Trial name
- NCT02974686
- Testing
- Everolimus, Mycophenolic Acid
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Washington University School of Medicine
Hepatocellular Carcinoma Non-resectable, Conversion
Non-inferiority Study of Unresectable Hepatocelluar Carcinoma Receiving Stereotactic Radiotherapy Combined With Hepatic Arterial Chemoembolization Compared With Conversion Hepatectomy
To compare the prognosis and adverse reactions of unresectable hepatocellular carcinoma receiving stereotactic radiotherapy combined with hepatic arterial chemoembolization and conversion hepatectomy
- Trial name
- NCT05057104
- Volunteers
- 320 people
- Sponsor
- Beijing 302 Hospital