Clinical trials: Copd Exacerbation Acute
Chronic Obstructive Pulmonary Disease, Acute Exacerbation of Chronic Obstructive Airways Disease
Home Non Invasive Ventilation (NIV) Treatment for COPD-patients After a NIV-treated Exacerbation
Background: In chronic obstructive pulmonary disease, the prognosis for patients who have survived an episode of acute hypercapnic respiratory failure due to an exacerbation is poor.
- Conditions
- Chronic Obstructive Pulmonary Disease, Acute Exacerbation of Chronic Obstructive Airways Disease, Chronic Hypercapnic Respiratory Failure
- Trial name
- NCT01513655
- Testing
- LTNIV
- Where
- 4 sites in Denmark
- Volunteers
- 150 people
- Sponsor
- University Hospital, Gentofte, Copenhagen
Acute Exacerbation of Chronic Obstructive Pulmonary Disease
The Effect of EDP on Diaphragmatic Function and Neural Respiratory Drive in Patient With AECOPD
Chronic Obstructive Pulmonary Disease (COPD) is a common respiratory disease characterized by airflow limitation that is progressive and not fully reversible.
- Trial name
- NCT03083418
- Testing
- control group, EDP
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Zhujiang Hospital
COPD Exacerbation, COPD Exacerbation Acute
Prehospital Non-invasive Ventilation for Acute Exacerbation of Chronic Obstructive Pulmonary Disease
The goal of this clinical trial is to test if treatment with prehospital Non-invasive ventilation (NIV) for patients with acute respiratory failure (ARF), due to acute exacerbation of chronic obstructive pulmonary disease…
- Conditions
- COPD Exacerbation, COPD Exacerbation Acute, Noninvasive Ventilation, Emergency Medical Services
- Trial name
- PRENIV (NCT06211920)
- Testing
- Non-invasive ventilation
- Where
- Denmark
- Volunteers
- 140 people
- Sponsor
- Central Denmark Region
COPD
Randomized Trial of the FreeAspire Versus PEP-bottle After Acute Exacerbation in COPD Patients
BACKGROUND: Studies have shown that COPD patients with bronchial hypersecretion have increased risk of acute exacerbations. FREE ASPIRE is an electro-medical device which removes bronchopulmonary secretions noninvasively, without…
- Trial name
- NCT02640430
- Testing
- standard treatment, Free Aspire
- Where
- 2 sites in Italy, Switzerland
- Volunteers
- 40 people
- Sponsor
- Maugeri Foundation
Exacerbation Copd, Acute Respiratory Distress
High Flow Nasal Cannula Versus Non-Invasive Ventilation in Exacerbations of Chronic Obstructive Pulmonary Disease
Chronic obstructive lung disease is a disabling disease that affects people usually after several years of smoke tobacco exposure and affects millions of patients worldwide.
- Conditions
- Exacerbation Copd, Acute Respiratory Distress, Acute Hypercapnic Respiratory Failure
- Trial name
- HiFOLD (NCT03033251)
- Testing
- Non Invasive Ventilation, High Flow Oxygen Cannula 50, High Flow Oxygen Cannula 30
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Unity Health Toronto
Chronic Obstructive Pulmonary Disease, Sepsis
Antibiotic/COPD in Acute Exacerbation of Chronic Obstructive Pulmonary Disease (COPD) Requiring Mechanical Ventilation
Although the use of antibiotics in the treatment of acute exacerbation of chronic obstructive pulmonary disease (COPD) is largely accepted, controversy remains regarding whether the choice of antibiotic has any impact on outcome.
- Conditions
- Chronic Obstructive Pulmonary Disease, Sepsis, Antibiotics
- Trial name
- NCT00791505
- Testing
- ciprofloxacin, trimethoprim-sulfamethoxazole
- Volunteers
- 170 people
- Sponsor
- University of Monastir
COPD Exacerbation Acute, Nutrition Poor
Is a Collective Person-centered Dialogue Intervention for Hospitalised COPD Patients Feasible?
The aim of this mixed methods trial is to investigate the feasibility of a collective person-centred dialogue (COPE-D) intervention delivered by an interdisciplinary team for a population of patients hospitalised and diagnosed…
- Conditions
- COPD Exacerbation Acute, Nutrition Poor, Physical Inactivity, Relatives
- Trial name
- COPE-D (NCT06242301)
- Testing
- The collective person-centered dialogue intervention
- Where
- Denmark
- Volunteers
- 11 people
- Sponsor
- Hvidovre University Hospital
Chronic Obstructive Pulmonary Disease (COPD)
Respiratory Rehabilitation Exercises in Older Adults With Acute Exacerbations of Chronic Obstructive Pulmonary Disease
The purpose of this randomized controlled trial was to evaluate the effects of a respiratory rehabilitation exercise training package on dyspnea, cough, exercise tolerance, and sputum expectoration of hospitalized elderly…
- Trial name
- NCT02329873
- Testing
- Respiratory rehabilitation exercise training
- Where
- Taiwan
- Volunteers
- 61 people
- Sponsor
- Chest Hospital, Ministry of Health and Welfare, Taiwan
COPD Exacerbation, COPD
Borg Score Outcomes in Respiratory Compromised Acute Exacerbating Chronic Obstructive Pulmonary Disease (COPD) Patients Receiving Treatment Via Vibrating Mesh Nebuliser Versus Jet Nebuliser in the Emergency Department
The purpose of this study is to compare clinical outcomes in patients with acute COPD treated with a vibrating mesh nebuliser (VMN) versus a current standard jet nebuliser (JN), in the Emergency Department (ED).
- Trial name
- BRAVE (NCT04181073)
- Testing
- Jet Nebuliser, Vibrating Mesh Nebuliser
- Where
- United Kingdom
- Volunteers
- 150 people
- Sponsor
- NHS Greater Clyde and Glasgow
Copd Exacerbation Acute
A Therapy for Improving Symptoms in Patients With Acute Exacerbations of COPD by Hydrogen-Oxygen Generator With Neburlizer.
The purpose for this study is to determine safety and effectiveness of the oxyhydrogen generator with nebulizer through a therapy for improving symptoms in patients with acute exacerbations of copd.
- Trial name
- NCT04000451
- Testing
- oxyhydrogen, Oxygen, Conventional treatment
- Where
- China
- Volunteers
- 108 people
- Sponsor
- Shanghai Asclepius Meditec Inc.
COPD Exacerbation, Hypoxia
Oxygen Control and Weaning by O2matic to Patients Admitted With an Exacerbation of COPD
The aim of the study is to examine if automated oxygen delivery with O2matic allows for faster weaning from oxygen and better oxygen control than manually controlled oxygen therapy for patients admitted with an exacerbation of…
- Conditions
- COPD Exacerbation, Hypoxia, Hypoxemia, Hyperoxia
- Trial name
- O2MATIC-WEAN (NCT03661086)
- Testing
- O2matic
- Where
- 5 sites in Denmark
- Volunteers
- 157 people
- Sponsor
- Hvidovre University Hospital
Chronic Obstructive Pulmonary Disease
Smart Telehealth Exercise Intervention to Reduce COPD Readmissions
This is a prospective randomized controlled study to test the hypothesis that neuromuscular electrical stimulation (NMES) and remote pulmonary rehabilitation at home offered via a smart technology, called Smart TeleHealth…
- Trial name
- NCT03089853
- Testing
- Neuromuscular electrical stimulation (NMES)
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- University of Alabama at Birmingham
COPD
Evaluation Of The Efficacy Of Corticosteroids In Patients With An Acute Exacerbation Of Chronic Obstructive Pulmonary Disease Receiving Ventilator Support
Clinical practice guidelines for the management of chronic obstructive pulmonary disease (COPD) recommend treatment with systemic corticosteroids during acute exacerbations.
- Trial name
- NCT01281748
- Testing
- intravenous methylprednisolone, intravenous normal saline solution
- Where
- Spain
- Volunteers
- 83 people
- Sponsor
- Hospital Universitario Getafe
Pulmonary Disease, Chronic Obstructive
The Impact of a Home-based Pulmonary Telerehabilitation Program in Acute Exacerbations of COPD
COPD impacts a significant proportion of the Veteran population. Acute exacerbations, or flare-ups, of COPD are associated with impaired muscle function and worse quality of life.
- Trial name
- NCT03997513
- Testing
- Pulmonary Telerehabilitation
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- VA Office of Research and Development
Chronic Obstructive Pulmonary Disease
Diagnostic Values of C-reactive Protein and Procalcitonin in Predicting Bacterial Infection in Acute Exacerbations of Chronic Obstructive Pulmonary Disease
Chronic obstructive pulmonary disease is a serious disease . Exacerbations of Chronic obstructive pulmonary disease is an acute worsening condition of Chronic obstructive pulmonary disease, which always accompanied by clinical…
- Trial name
- NCT03923803
- Testing
- C- reactive protein, Pro calcitonin
- Volunteers
- 90 people
- Sponsor
- Assiut University
Chronic Obstructive Pulmonary Disease (COPD)
Prevention of Acute Exacerbation in Subjects With COPD by Bacterial Decolonization in Lower Respiratory Tract
The colonization of potential pathogenic bacteria in lower respiratory tract is thought to be accountable for acute exacerbation in subjects with moderate to severe COPD.
- Trial name
- PAEAN (NCT03449459)
- Testing
- oral probiotics, aerosol inhaled amikacin, combined vaccination
- Where
- 3 sites in China
- Volunteers
- 144 people
- Sponsor
- Shanghai Zhongshan Hospital