Clinical trials: Cor Pulmonale
Cardiopulmonary Disease, Surgery
Focused Cardiac Ultrasound in Surgery
Mortality and morbidity remain high after non-cardiac surgery. Known risk factors include age, high ASA grade and emergency surgery.
- Conditions
- Cardiopulmonary Disease, Surgery, Morality, Complication
- Trial name
- PreOPFOCUS (NCT03501927)
- Testing
- FOCUS (focused cardiac ultrasound)
- Where
- Denmark
- Volunteers
- 337 people
- Sponsor
- Aarhus University Hospital
Cardiopulmonary Disease
Unmasking Right Ventricular and Pulmonary Derangements With Exercise and Oxygen in Early Stage Cardiopulmonary Diseases
Researchers are trying to develop innovative strategies that target the early identification heart and lung imbalances in patients with cardiopulmonary diseases.
- Trial name
- NCT03911856
- Testing
- Echocardiography, Pulmonary Gas Exchange
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Heart Diseases, Heart Valve Diseases
Acute Kidney Injury After Cardiac Surgery
The study aims to identify the Following: - 1. incidence and mortality of cardiac Surgery associated -AKI based on the new consensus diagnostic systems of KDIGO (Kidney Disease Improving Global Outcomes). 2.
- Conditions
- Heart Diseases, Heart Valve Diseases, Heart Shock, Cardiac Disease
- Trial name
- NCT05079724
- Testing
- Cardiac Surgery
- Volunteers
- 200 people
- Sponsor
- Assiut University
Chest Pain, Dyspnea
ER-VISION-AI Study
Prospective, multicenter, randomized, open-label, blinded-endpoint (PROBE-like) clinical trial evaluating whether physician-supervised Generative Pre-trained Transformer (GPT)-assisted multimodal diagnostic support improves…
- Conditions
- Chest Pain, Dyspnea, Acute Cardiopulmonary Disease, Emergency Department Patients
- Trial name
- ER-VISION-AI (NCT07727590)
- Testing
- Generative Pre-trained Transformer (GPT)-assisted multimodal visual language model (VLM) diagnostic support, Conventional emergency department diagnostic evaluation
- Where
- South Korea
- Volunteers
- 1,000 people
- Sponsor
- Ewha Womans University Mokdong Hospital
Cardiac Disease, Cardiopulmonary Disease
World Trade Center (WTC) RENAL
Environmental toxins exert damaging health effects in workers. Thousands of responders who worked or volunteered on the World Trade Center (WTC) rescue and recovery effort following the September 11, 2001 attacks suffer from…
- Conditions
- Cardiac Disease, Cardiopulmonary Disease, Renal Disease, Cardiovascular Disease
- Trial name
- NCT02246101
- Where
- United States
- Volunteers
- 406 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Cardiopulmonary Diseases
Indoor Air Filtration and Young Adults Health Study
This study aims to explore the cardiopulmonary health effects of indoor air purification and other indoor environmental conditions among young healthy college students in Beijing, China.
- Trial name
- NCT05172388
- Testing
- Air purifier
- Where
- China
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Peking University
Sickle Cell Anemia
Exercise Capacity in Pediatric Sickle Cell Anemia
The purpose of this study is to use comprehensive exercise testing to examine causes of exercise limitation in children and young adults with sickle cell anemia.
- Trial name
- NCT01527799
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Chronic Cor Pulmonale
The Effect of External Diaphragmatic Pacemaker on the Patients With Chronic Cor Pulmonale
This study evaluates the effect of external diaphragmatic pacemaker on the patients with chronic cor pulmonale. Half of participants will receive external diaphragmatic pacemaker, while the other half will receive routine therapy.
- Trial name
- NCT02976324
- Testing
- external diaphragmatic pacemaker group
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Zhang Xiangyu
Sleep Disordered Breathing, Sleep Apnea
Sleep Disordered Breathing and Cardiopulmonary Disease in Peruvian Highlanders
Overall objective: To understand the feasibility of performing a randomized trial using a simple, minimally-invasive postural therapy approach to improve sleep disordered breathing (SDB).
- Trial name
- NCT03927547
- Testing
- Inclined Sleep
- Where
- Peru
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Heart Failure, Pulmonary Hypertension
Cardiopulmonary Interactions in Patients With Heart Failure
This study aims to evaluate cardiopulmonary interactions in patients with heat failure
- Conditions
- Heart Failure, Pulmonary Hypertension, Heart Failure With Reduced Ejection Fraction, Heart Failure With Normal Ejection Fraction
- Trial name
- NCT03317314
- Testing
- Lung Biopsy during LVAD Implantation
- Where
- Germany
- Sponsor
- Hannover Medical School
Myocardial Infarction, Cardiopulmonary Disease
The Effect of HIIT, MICT in Patients With Myocardial Infarction
This study will investigate the effect of a 12-weeks cardiac rehabilitation training (HIIT, MICT) program on VO2peak and cardiac fibrosis in patients, and evaluate the effects of HIIT on endothelial function, microvascular…
- Conditions
- Myocardial Infarction, Cardiopulmonary Disease, Training Group, Sensitivity
- Trial name
- NCT04863677
- Testing
- High Intensity Interval Training(HIIT）, Moderate Intensity Continuous Training(MICT）
- Where
- China
- Volunteers
- 188 people
- Sponsor
- Guangdong Provincial People's Hospital
Congenital Heart Disease
Efficacy of Remodulin in Adults With Congenital Heart Disease (ACHD) and Pulmonary Hypertension
The purpose of this study is to evaluate the efficacy of Remodulin in the treatment of adult patients with congenital heart disease and pulmonary hypertension.
- Trial name
- NCT01980979
- Testing
- Remodulin
- Where
- 2 sites in United States
- Sponsor
- University of California, Los Angeles
Respiratory Tract Diseases, Cardiac Diseases
Cardiopulmonary Effects of Particulate Exposure
The aim of this study is to assess cardiac rate and respiratory responses and rhythm after workplace exposure to combustion particulates.
- Conditions
- Respiratory Tract Diseases, Cardiac Diseases, Bronchitis
- Trial name
- NCT00011310
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
Outpatients, Cardiology
Interpretation Performance in Chinese and Japanese Medical Consultation Scenarios
This study aims to compare the translation and interpretation performance of ChatGPT, Google Translate(GT),and UD Talk in cardiopulmonary consultations and analyze their effectiveness in addressing language barriers.The…
- Conditions
- Outpatients, Cardiology, Pulmonology
- Trial name
- NCT06934031
- Testing
- translation software
- Where
- Taiwan
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Fu Jen Catholic University
Chronic Obstructive Pulmonary Disease, Interstitial Lung Disease
Move With Air: Physiological Response Assessment
A fan blowing cool air to the face has been shown to alleviate breathlessness in malignant and non-malignant disease at rest and during exercise, however the underlying physiological mechanisms remain unknown.
- Conditions
- Chronic Obstructive Pulmonary Disease, Interstitial Lung Disease, Heart Failure
- Trial name
- NCT05659550
- Testing
- Honeywell HT-900 Turbo Force Air Circulator
- Where
- Canada
- Volunteers
- 21 people
- Sponsor
- McGill University
Cardiopulmonary Disease, Smoking Cessation
Smoking Cessation Pharmacotherapy-Nurse Practitioner Led Tobacco Treatment Team Study
Tobacco use remains the leading cause of death in the United States and contributes to more than 7 million hospitalizations annually. Being admitted to the hospital offers the perfect opportunity to support smoking cessation.
- Conditions
- Cardiopulmonary Disease, Smoking Cessation, Inpatient
- Trial name
- STOP-NPT3 (NCT05733767)
- Testing
- Enhanced Usual Care (EUC), Nurse Practitioner Tobacco Treatment Team (NPT3)
- Where
- United States
- Volunteers
- 424 people
- Sponsor
- Baystate Medical Center
Pulmonary Hypertension, Heart Failure With Normal Ejection Fraction
Chlorhexidine Mouthwash and Oral Nitrate in Adults With Pulmonary Hypertension
This is an open-label, single-center study to examine distinguishing features of the structure and function of the oral and gut microbiome in volunteers with PH in the breakdown of oral nitrate and effect on hemodynamics.
- Conditions
- Pulmonary Hypertension, Heart Failure With Normal Ejection Fraction, Pulmonary Heart Disease and Diseases of Pulmonary Circulation
- Trial name
- NCT03787082
- Testing
- Nitrates, Chlorhexidine Gluconate Mouthwash
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Gladwin, Mark, MD
Pulmonary Disease, Cardiac Disease
World Trade Center (WTC) CHEST
This project will evaluate the effects of World Trade Center (WTC) exposure in WTC responders 10-13 years following the events of 9/11.
- Conditions
- Pulmonary Disease, Cardiac Disease, Cardiopulmonary Disease, Obstructive Sleep Apnea
- Trial name
- NCT01466218
- Where
- United States
- Volunteers
- 1,012 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Pulmonary Hypertension
PHIRST-1: Tadalafil in the Treatment of Pulmonary Arterial Hypertension
The purpose of this study is to evaluate the safety and effectiveness of tadalafil for the treatment of pulmonary arterial hypertension.
- Trial name
- NCT00125918
- Testing
- tadalafil
- Where
- 6 sites in United States, France and 1 more
- Volunteers
- 406 people
- Sponsor
- Eli Lilly and Company
Mechanical Ventilation, Acute Respiratory Distress Syndrome (ARDS)
Relationship Between the Level of Positive End-expiratory Pressure and Venous Congestion During Acute Respiratory Distress Syndrome.
The main objective is to assess the effect of increased PEEP on echo-Doppler venous congestion in ARDS patients at two PEEP levels, by grading congestion in each venous flow (suprahepatic, renal, portal) as "absent," "moderate,"…
- Trial name
- SURVEX (NCT07452952)
- Testing
- Non-interventionnal study
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Angers