Clinical trials: Cord Clamping
Neonatal Anemia
Milking Versus Delayed Cord Clamping in Full Term Neonates
To compare the short term risks and benefits of cord milking 5 times toward the neonate with delayed cord clamping for 120 seconds in the full term neonate delivered by cesarean section.
- Trial name
- MDCCT (NCT02454101)
- Testing
- cord milking, delayed cord clamping
- Where
- Egypt
- Volunteers
- 300 people
- Sponsor
- Ahmed Mohamed El Kotb Abdel Fattah
Placental Transfusion
Short-Delay Cord Clamping Compared to Extended- Delay Cord Clamping in Term Neonates That Require Resuscitation.
To determine whether performing extended delayed cord clamping in term neonates that require resuscitation improves early transition as compared to short-delayed cord clamping.
- Trial name
- Term-NRIC (NCT02827409)
- Testing
- Short Delay Cord Clamping, Extended Delay Cord Clamping
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Anup Katheria, M.D.
Breastfeeding, Exclusive
Interventions That Promote Exclusive Breastfeeding
Delayed umbilical cord clamping as well as immediate skin-to-skin contact between mother and newborn are emerging practices due to documented benefits. However, in caesarean sections it is not common.
- Trial name
- NCT04052984
- Testing
- Delayed umbilical clamping and immediate skin-to-skin contact after birth by caesarean section
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Asociacion Mexicana de Nacimiento Respetado, A.C.
Ductus Arteriosus
Effect of Umbilical Cord Milking Versus Clamping in Preterms on Cerebral Oxygenation and Ductus Arteriosus Closure
All patients will be subjected to the following: 1-Umbilical cord milking or delayed cord clamping according to the ranamization table 2 serial measurement of cerebral tissue oxygenation 3- serial echocardiography for ductus…
- Trial name
- NCT05922488
- Testing
- Umbilical cord milking, delayed cord clamping
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Ain Shams University
Cardiac Output, High, Cardiac Output, Low
Hemodynamic Effects of Delayed Umbilical Cord Clamping in Full-term Newborns
The sequence of events at the time of delivery includes delivery of the infant, clamping of the umbilical cord, and lastly delivery of the placenta. There are some benefits for delayed cord clamping.
- Trial name
- NCT04358822
- Testing
- Delayed cord clamping
- Where
- Egypt
- Volunteers
- 68 people
- Sponsor
- Cairo University
Hypoxia, Brain, Premature Birth
PREMOD2 With Near Infrared Spectroscopy Sub-study
Early hemodynamic effects (within 3 hours of life) of Delayed Cord Clamping compared to Umbilical Cord Milking are still unknown.
- Trial name
- PREMOD2 (NCT03145142)
- Testing
- Umbilical cord milking, Delayed Cord Clamping
- Where
- 4 sites in United States, Canada and 2 more
- Volunteers
- 121 people
- Sponsor
- Sharp HealthCare
Newborn Infant, Newborn Health
The Effect of Different Positions Given to the Newborn During Delayed Cord Clamping on Physiological Indicators and Comfort
During intrauterine life, the fetus is connected to the mother via the placenta; with birth, the extrauterine adaptation process begins.
- Conditions
- Newborn Infant, Newborn Health, Delayed Cord Clamping
- Trial name
- Cord Clamping (NCT07719751)
- Testing
- Prone position, Left side lying position
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Mersin University
Cesarean Section, Infant Conditions
Intact-cord Stabilisation and Physiology-based Cord Clamping in Caesarean Sections
This is a feasibility study with historical control designed to evaluate whether delivery of the placenta prior to umbilical cord clamping at caesarean sections is a feasible, safe and acceptable way of facilitating intact-cord…
- Trial name
- INTACT (NCT05461950)
- Testing
- Extrauterine placental transfusion and physiology-based umbilical cord clamping, Extrauterine placental transfusion, intact cord stabilisation and physiology-based umbilical cord clamping, Delayed umbilical cord clamping
- Where
- Norway
- Volunteers
- 263 people
- Sponsor
- Helse Møre og Romsdal HF
Placental Transfusion, Hematocrit Anemia
Delayed Cord Clamping in Infants Born by 'Two-step' Vaginal Delivery
The investigators conducted a RCT (parallel group study with 1:1 randomisation) comparing ECC (at 60 seconds) and DCC (at 180 seconds) in 90 cases of normal birth by' two-step' delivery.
- Trial name
- NCT04351997
- Testing
- Cord clamping
- Where
- 3 sites in Italy
- Volunteers
- 90 people
- Sponsor
- Policlinico Abano Terme
Newborn; Anemia, Umbilical Cord Problem
Supine vs Prone Position During Delayed Cord Clamping
This study is conducted to evaluate if the prone position of the newborn on the chest of his mother at birth before delayed cord clamping leads to better hematocrit and hemoglobin at 24-48 hours of life compared to supine…
- Trial name
- DCC (NCT03697967)
- Testing
- supine or prone position
- Where
- Canada
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Maisonneuve-Rosemont Hospital
Delayed Cord Clamping, Umbilical Cord Milking
The Hematologic Impact of Umbilical Cord Milking Versus Deferred Cord Clamping in Premature Neonates.
Comparing the beneficial effect of cord milking versus deferred cord clamping in preterm neonates. A randomized controlled trial
- Conditions
- Delayed Cord Clamping, Umbilical Cord Milking, Preterm Neonates
- Trial name
- NCT03147846
- Testing
- delayed cord clamping, cord milking
- Where
- Saudi Arabia
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Low Birth Weight, Perinatology
Effect of Delayed Cord Clamping on Haematological Status in Low Birth Weight Infants
Delayed cord clamping (DCC, clamping after cessation of pulsations in the cord around 2-3 min after delivery) is effective in increasing (low birth weight) infant haemoglobin and iron status until six months after birth, without…
- Conditions
- Low Birth Weight, Perinatology, Iron Status, Cord Clamping
- Trial name
- NCT01487980
- Testing
- Cord clamping
- Where
- South Africa
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Stanger Hospital
Elective Cesarean Section
Antibiotic Prophylaxis Before Surgery Versus After Cord Clamping in Elective Cesarean Delivery - a Double-blind, Prospective, Randomized Placebo-controlled Trial
In this prospective, randomized, placebo controlled trial the investigators were able to demonstrate the usefulness of prophylactic cefazolin in elective caesarean section versus placebo, irrespective of the timing of…
- Trial name
- NCT01248078
- Testing
- Keflex, saline solution
- Where
- Austria
- Volunteers
- 1,112 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Very Low Birth Weight Infants, Premature Infants
Delayed Cord Clamping in Very Low Birth Weight Infants
The purpose of this study is to determine if there is a difference in neonatal outcomes with delayed umbilical cord clamping at 30 versus 60 seconds.
- Conditions
- Very Low Birth Weight Infants, Premature Infants, Intraventricular Hemorrhage
- Trial name
- DCC (NCT02337088)
- Testing
- Delayed cord clamping at 30 seconds, Delayed cord clamping at 60 seconds
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- University of Chicago
Umbilical Cord; Clamping Time
The Effect of Delayed Cord Clamping and Milking on the Amount of Stem Cells In Preterm
Stem cell therapies have been promising therapies in neonatal morbidities such as bronchopulmonary dysplasia, intraventricular hemorrhage and hypoxic ischemic encephalopathy.
- Trial name
- NCT04057027
- Testing
- Delayed umbilical cord clamping, Cord Milking
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Microbial Colonization, Antibiotic Side Effect
Timing of Maternal Antibiotic Prophylaxis During a Cesarean Section and the Early Infant Gut Microbiome
In this study, investigators seek to determine whether the timing of antibiotics given to mothers during an elective C-section affects the composition of their infant's gut microbiome.
- Conditions
- Microbial Colonization, Antibiotic Side Effect, Cesarean Section Complications
- Trial name
- CSBabyBiome (NCT06030713)
- Testing
- Cefazolin
- Where
- Netherlands
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- University Medical Center Groningen
Delayed Cord Clamping
Prone Positioning During Delayed Cord Clamping
Delayed cord clamping is a routine technique used in the delivery room. The baby remains attached to the umbilical cord and placenta for 30-60 seconds after birth to allow for maximal transfer of oxygen and blood to the newborn.
- Trial name
- NCT05507424
- Testing
- Prone Positioning, Supine Positioning
- Where
- 2 sites in United States
- Volunteers
- 89 people
- Sponsor
- Johns Hopkins University
Intraventricular Haemorrhage Neonatal, Death; Neonatal
Premature Infants Receiving Milking or Delayed Cord Clamping: PREMOD2
This study is being done to find out whether umbilical cord milking (UCM) is at least as good as or better than delayed cord clamping (DCC) to reduce bleeding in the brain or prevent death in premature newborns.
- Trial name
- PREMOD2 (NCT03019367)
- Testing
- Umbilical cord milking UCM, Delayed cord clamping DCC
- Where
- 18 sites in United States, Canada and 2 more
- Volunteers
- 1,201 people
- Sponsor
- Sharp HealthCare
Umbilical Cord Management, Elective Cesarean Section
Delayed Cord Clamping in Infants Born by Cesarean Section
Introduction: Placental transfusion supports an important blood transfer to the neonate, promoting a more stable and smooth transition from fetal to extra-uterine life.
- Trial name
- NCT03549884
- Testing
- Delayed cord clamping, Early cord clamping
- Where
- Italy
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University Hospital Padova
Hyperbilirubinemia, Neonatal, Jaundice, Neonatal
Relationship Between Delayed Cord Clamping at Birth and Neonatal Bilirubin Levels in Parturients With a Prior Child Requiring Therapy for Neonatal Jaundice
The purpose of the study is to determine if neonates (who already have an increased risk of hyperbilirubinemia due to mother's history of having previous neonate who received phototherapy for hyperbilirubinemia) have higher…
- Trial name
- NCT03741803
- Testing
- Delayed cord clamping, Early cord clamping
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- The University of Texas Health Science Center, Houston