Clinical trials: Corneal Biomechanics
Myopia, Astigmatism
Toric Orthokeratology - Slowing Eye Elongation
The aims of this study are to investigate the effects of ortho-k for astigmatic and myopic reduction and myopic control in children, and the long term effects on corneal curvatures and biomechanics.
- Trial name
- TO-SEE (NCT00978692)
- Testing
- Toric Orthokeratology lenses, Single-vision spectacles
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Conjunctivitis, Allergic, Keratoconus
Corneal Biomechanical Changes of Allergic Conjunctivitis
By measuring and comparing the corneal biomechanical parameters of normal people, patients with allergic conjunctivitis, keratoconus, whether allergic conjunctivitis causes changes in corneal biomechanics can be explored, and…
- Trial name
- NCT04299399
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Ciliary Muscle Thickness, Anterior Sclera Thickness
Correlation Analysis Between Corneal Biomechanics and Anterior Segment
Evaluation of the ciliary muscle thickness, area, and anterior chamber angle, as well as anterior sclera thickness in subjects, to investigate the relationship between these measurements and corneal biomechanics.
- Conditions
- Ciliary Muscle Thickness, Anterior Sclera Thickness, Corneal Biomechanics, CASIA2
- Trial name
- NCT06109636
- Testing
- Pentacam, Corvis ST and Casia2
- Where
- China
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Tianjin Eye Hospital
Cornea
Age-dependency of Cornea Biomechanics Using OCT Vibrography
The aim of this pilot study is to assess the ability of a new optical coherence tomography system to obtain information on biomechanics of the cornea.
- Trial name
- NCT03230981
- Testing
- Optical imaging of the cornea in healthy subjects
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Laser Corneal Surgery
Corneal Biomechanics With Hydration in Normal and LASIK Eyes
The research will utilize LASIK and non-LASIK populations to analyze the biomechanical differences between these corneas.
- Trial name
- NCT01183702
- Testing
- LASIK surgery, No Intervention
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Deb Grzybowski
Corneal Biomechanics
Evaluation of the Change in the DA Ratio, IR and SSI as Parameters of Corneal Biomechanics Post Different LVC Procedures
In the study, The Investigators will compare the participates' corneal biomechanical properties including: Deformation Amplitude ratio (Da Ratio) Integrated Radius (IR) Stress strain index (SSI) All measurements will be taken…
- Trial name
- NCT05377099
- Testing
- CORVIS
- Where
- Egypt
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Cairo University
Pseudoexfoliation Syndrome, Cataract
Corneal Biomechanics and Surgically Induced Astigmatism in Pseudoexfoliation Syndrome
This prospective study aims to evaluate the influence of corneal biomechanical properties on surgically induced astigmatism following standard phacoemulsification cataract surgery in patients with pseudoexfoliation syndrome…
- Conditions
- Pseudoexfoliation Syndrome, Cataract, Astigmatism
- Trial name
- NCT07722247
- Testing
- phacoemulsification cataract surgery
- Where
- Croatia
- Volunteers
- 70 people
- Sponsor
- Kata Culina
Corneal Biomechanics, Pregnancy
Corneal Biomechanical Properties in Pregnancy
57 eyes of 57 healthy pregnant women who were visiting Obstetrics and Gynecology department for routine examination and 26 eyes of 26 non pregnant control subjects who were at the first week of the menstrual cycle were enrolled…
- Trial name
- NCT03500523
- Testing
- corneal biomechanical properties
- Where
- Turkey (Türkiye)
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Medipol University
Silicon Oil Effect on Cornea, Corneal Biomechanics
Silicone Effect on Corneal Endothelium and Corneal Biomechanics Using Corvis ST
Brief Summary The goal of this observational study is to investigate the effects of silicone oil tamponade on corneal endothelial cell density (ECD), morphology, and biomechanics in patients undergoing vitrectomy for retinal…
- Trial name
- NCT06861946
- Testing
- Corvis ST, Conrneal endothelial cell density
- Where
- 2 sites in Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Beni-Suef University
Pregnancy
The Influence of Hormonal Changes During Pregnancy on Corneal Biomechanics in Humans
The intraocular pressure in the human bulbus requires that the "wall" of the eye shows a certain (bio)mechanical strength. The human cornea represents the anterior portion of this wall.
- Trial name
- NCT01629264
- Testing
- Ocular Response Analyzer, Scheimpflug measurement, Blood sample
- Where
- Switzerland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University Hospital, Geneva
Glaucoma
The Aim of This Study is to Investigate the Correlation Between the Severity of Glaucoma and Corneal Biomechanics as Well as Anterior Chamber Parameters.
The ocular biomechanical differences between the normal control group and primary glaucoma patients, including those treated with conventional medication, laser therapy, and surgery, were compared.
- Trial name
- NCT06340061
- Testing
- Observational study
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Henan Provincial People's Hospital
Glaucoma, Open-Angle
The Impact of Topical Prostaglandins on the Biomechanical Properties of the Cornea in Patients With Open Angle Glaucoma
The purpose of this study is to determine the influence of topical prostaglandin analog (PGA) medication on corneal biomechanical properties in patients undergoing PGA treatment for open-angle glaucoma.
- Trial name
- NCT02388360
- Testing
- topical prostaglandin analogs
- Where
- Canada
- Volunteers
- 35 people
- Sponsor
- Maisonneuve-Rosemont Hospital
Pseudoexfoliation Syndrome, Biomechanical Parameters
Corneal Biomechanics, Optical Properties and Anterior Segment Structural Features in Patients With Pseudoexfoliation
The purpose of this study is to assess the effect of pseudoexfoliation syndrome on corneal biomechanics, optical clarity of the cornea, and anterior segment structural features.
- Conditions
- Pseudoexfoliation Syndrome, Biomechanical Parameters, Corneal Densitometry
- Trial name
- CorPEX (NCT06731530)
- Testing
- Pentacam-AXL, HD Analyzer, Corvis ST
- Where
- Greece
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki