Clinical trials: Corneal Endothelial Dystrophy
Retinal Detachment, Epiretinal Membrane
PIONEER: Intraoperative and Perioperative OCT Study
OCT provides high-resolution information regarding the anatomic structure of the tissues of the eye in a 2-dimensional and 3-dimensional view. Much of this information is not able to be recognized by a clinician.
- Conditions
- Retinal Detachment, Epiretinal Membrane, Macular Hole, Fuchs Endothelial Dystrophy
- Trial name
- PIONEER (NCT02423161)
- Where
- United States
- Volunteers
- 750 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Fuchs' Endothelial Corneal Dystrophy
Study to Investigate the Safety and Efficacy of K-321 in Patients With Fuchs Endothelial Corneal Dystrophy (FECD) Following Descemetorhexis
The objective of this study is to investigate the effect of K-321 in patients with Fuchs endothelial corneal dystrophy (FECD) after descemetorhexis.
- Trial name
- NCT04250207
- Testing
- K-321 Solution
- Where
- 29 sites in United States, Australia and 3 more
- Volunteers
- 65 people
- Sponsor
- Kowa Research Institute, Inc.
Fuch's Endothelial Dystrophy, Pseudophakic Bullous Keratopathy
Comparison of Corneal Grafts Cultured in Serum-free Versus Corneal Grafts Cultured in Serum Supplemented Culture Media
The goal of this clinical trial is to compare the quality of corneal grafts cultured in a serum-free culture medium with a defined composition versus corneal grafts cultured in a standard serum supplemented culture medium…
- Trial name
- SFM (NCT00623584)
- Testing
- Corneal transplantation
- Where
- 2 sites in Germany
- Volunteers
- 60 people
- Sponsor
- Klinikum Chemnitz gGmbH
Fuch's Endothelial Dystrophy, Cataracts
Study of the Effect of Aspheric Lenses in Patients With Fuch's Dystrophy
The proposed study will recruit patients with mild to moderate Fuch's dystrophy who need cataract surgery alone. They will be randomly assigned to receive either spheric or aspheric lenses.
- Trial name
- NCT02109276
- Testing
- Spheric Sensar(R) 3-piece IOL, Aspheric Tecnis(R) 3-piece IOL
- Where
- Canada
- Sponsor
- Queen's University
Fuchs Endothelial Corneal Dystrophy
Targeting Reactive Oxygen Species Production as a Novel Therapeutic in Fuch's Endothelial Corneal Dystrophy
This protocol will investigate whether topical application of N-acetyl cysteine (NAC) eye drops decreases oxidative stress and confers cytoprotection in patients with FECD.
- Trial name
- NCT04440280
- Testing
- N-acetyl cysteine (NAC) 10% solution, N-acetyl cysteine (NAC) 20% solution, Visine Dry Eye Relief eye drops
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Massachusetts Eye and Ear Infirmary