Clinical trials: Corneal Injuries
Eye Injuries, Critically Ill
Does the Use of a Moisture Chamber Decrease the Incidence of Corneal Abrasions in Critically Ill Pediatric Patients?
The purpose of this study is to identify the incidence of scratches on the surface of the eye in children who cannot blink due to medication use and to identify how best to reduce the risk of a scratch on the surface of the eye…
- Trial name
- NCT00129077
- Testing
- plastic wrap over eye & lubrication applied q6 hrs
- Where
- 2 sites in United States
- Volunteers
- 207 people
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Corneal Diseases
Effect of Systemic Oxygen on Corneal Epithelial Wound Healing in Diabetic Patients Undergoing Pars Plana Vitrectomy
1. To compare the corneal epithelial defect healing time between diabetic patients receiving and not receiving supplementary oxygen after vitrectomy. 2.
- Trial name
- NCT02344732
- Testing
- Dexamethasone 0.1%, Neomycin Sulfate and Polymyxin B Sulfate topical eye drops four times daily, Homatropine 2% eye drops thrice daily, Oxygen gas
- Volunteers
- 32 people
- Sponsor
- Universiti Sains Malaysia
Keratoconus, Cornea Disease
Effects of Topical Insulin on Corneal Epithelium Healing After Corneal Crosslinking in Patients With Keratoconus
The cornea plays a fundamental role in vision, being a complex tissue essential for ocular health. In ophthalmological practice, there are situations such as corneal crosslinking, where damage to the corneal epithelium occurs.
- Conditions
- Keratoconus, Cornea Disease, Eye Diseases, Wound Heal
- Trial name
- NCT06601101
- Testing
- Insulin
- Where
- Brazil
- Volunteers
- 36 people
- Sponsor
- University of Campinas, Brazil
Corneal Perforation
Role of AS-OCT in Assessment of Corneal Perforation
Assessment of healing of thin and perforated cornea after surgical treatment by anterior segment optical coherence tomography
- Trial name
- OCT (NCT06422897)
- Testing
- anterior segment optical coherence tomography
- Where
- Egypt
- Volunteers
- 13 people
- Sponsor
- Minia University
Corneal Perforation, Exposure Keratitis
The Role of OmniLenz® in the Treatment of Small Corneal Perforations Secondary to Exposure Keratitis in ICU Patients
Case series of 5 ICU patients in Farwaniya Hospital who developed exposure keratitis and a subsequent small corneal perforation between April 2022 and April 2024.
- Conditions
- Corneal Perforation, Exposure Keratitis, Infectious Keratitis
- Trial name
- NCT06539663
- Testing
- OmniLenz®
- Where
- Kuwait
- Volunteers
- 5 people
- Sponsor
- Farwaniya Hospital
Healthy Volunteers
Study of the Safety of USB005 in Healthy Volunteers
This study will evaluate the safety, tolerability and pharmacokinetics of USB005 (aclerastide) Ophthalmic Solution.
- Trial name
- NCT03615196
- Testing
- USB005 (aclerastide) Ophthalmic Solution
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- US Biotest, Inc.
Cataract Surgery, Cataract (Post-operative Cataract Surgery Follow-up)
Subincisional Pockets for Sealing Clear Corneal Incisions in Cataract Surgery
The main goal of the sub-incisional pocket (SIP) is to provide a wound seal option during corneal surgery. This retrospective cohort study aims to report the efficacy and safety of SIP among eyes undergoing routine cornea surgery…
- Conditions
- Cataract Surgery, Cataract (Post-operative Cataract Surgery Follow-up), Phacoemulsification Cataract Surgery, Wound Closure Technique
- Trial name
- SIPSIP (NCT07821203)
- Testing
- Sub-Incisional Pocket
- Where
- Philippines
- Volunteers
- 35 people
- Sponsor
- Philippine Eye Research Institute