Clinical trials: Corneal Opacity
Corneal Disease, Corneal Opacity
First in Human (FIH) Study to Assess Safety and Efficacy of the CorNeat KPro for the Treatment of Corneal Blindness
Prospective, open label, single arm, First in Human (FIH) clinical study to assess safety and efficacy of the CorNeat Keratoprosthesis, a synthetic cornea, for the treatment of corneal blindness
- Conditions
- Corneal Disease, Corneal Opacity, Corneal Injuries
- Trial name
- NCT04485858
- Testing
- CorNeat KPro
- Where
- 8 sites in United States, Canada and 3 more
- Volunteers
- 10 people
- Sponsor
- CorNeat Vision Ltd.
Corneal Opacity, Keratoconus
OCT-guided LALAK for KCN
The purpose of this study is to determine if a new procedure, called laser-assisted lamellar anterior keratoplasty (LALAK), can achieve the same level of vision with a lower risk of potential complications after surgery compared…
- Trial name
- NCT01901614
- Testing
- LALAK, IEK, Retrobulbar Block or General Anesthesia
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Oregon Health and Science University
Keratitis, Pterygium
Robotic Surgery of the Ocular Surface
The introduction of surgical robots in the OR revolutionized a number of specialties (i. e. urology, gynecology, digestive surgery).
- Conditions
- Keratitis, Pterygium, Corneal Opacity Corneal Thinning, Corneal Perforation
- Trial name
- NCT02116062
- Testing
- 1. Amniotic membrane transplantation on the cornea with the Da Vinci Si HD© robot (Inlay or overlay technique), Pterygium removal and autograft of the conjunctiva with the Da Vinci Si HD© robot (Kenyon technique), Penetrating keratoplasty using Baron trephine and nylon stitches with the Da Vinci Si HD© robot
- Where
- France
- Volunteers
- 12 people
- Sponsor
- University Hospital, Strasbourg, France
Corneal Ulcer, Leukoma
Safety and Effectiveness of Collagen-phosphorylcholine Bioengineered Cornea in Patients Requiring Lamellar Keratoplasty
In this study the safety and effectiveness of biosynthetic cornea, comprising interpenetrating networks of recombinant human collagen and phosphorylcholine, will be tested in patients with severe corneal pathology (corneal ulcers…
- Trial name
- NCT02277054
- Testing
- Collagen-MPC cornea
- Where
- Ukraine
- Volunteers
- 5 people
- Sponsor
- The Filatov Institute of Eye Diseases and Tissue Therapy
Corneal Scars and Opacities
Limbus-derived Stem Cells for Prevention of Postoperative Corneal Haze
This is a investigator-initiated pilot clinical trial to ascertain the safety and efficacy of application of ex-vivo cultivated limbal stem cells in human eyes for treating Corneal Haze after Photo-Therapeutic/Refractive…
- Trial name
- NCT03295292
- Testing
- Stem cells, Vehicle
- Where
- India
- Volunteers
- 15 people
- Sponsor
- L.V. Prasad Eye Institute
Keratoconus, Corneal Opacity
Femtosecond Laser-assisted Anterior Lamellar Keratoplasty
The purpose of the study is evaluating safety and clinical efficiency of full femtosecond laser-assisted anterior lamellar keratoplasty (FS-ALK) for curing patients with keratoconus and corneal opacities
- Trial name
- NCT02301598
- Testing
- FS-ALK (Femtolaser-assisted anterior lamellar keratoplasty)
- Volunteers
- 13 people
- Sponsor
- The S.N. Fyodorov Eye Microsurgery State Institution
Corneal Blindness
A Clinical Study to Evaluate the KeraKlear Keratoprosthesis in Patients With Corneal Opacity
To evaluate the safety and probable benefit of the KeraKlear Non-Penetrating Keratoprosthesis when implanted in an eye with corneal opacity that is at high risk of complications with PK.
- Trial name
- NCT03126903
- Testing
- KeraKlear Non-Penetrating Keratoprosthesis
- Where
- 4 sites in United States
- Volunteers
- 11 people
- Sponsor
- KeraMed, Inc.
Corneal Opacity
The Use of MMC During PRK and Its Effect on Postoperative Topical Steroid Requirements
1. Purpose To evaluate the use of mitomycin-C (MMC) as an intraoperative adjunct during photorefractive keratectomy (PRK), its effect on postoperative healing and its ability to reduce the postoperative topical steroid course…
- Trial name
- NCT02030990
- Testing
- Mitomycin-C, Fluorometholone 1% topical ocular steroid
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- United States Naval Medical Center, San Diego