Clinical trials: Corona Virus Disease
Covid19, Corona Virus Infection
T Cells Response to SARS COV 2 Peptides
The analysis method described in this protocol is a novel simple plausible immunological approach which is non-invasive, high throughput, real-time quantitative monitoring of metabolic activity (MA) profiles of fresh Peripheral…
- Trial name
- NCT04573348
- Testing
- Savicell's ImmunoBiopsy™
- Where
- Israel
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Savicell Diagnostics Ltd
Corona Virus Infection, Stroke
Physiotherapy as a Complimentary Treatment in Reducing Viral-Load, Complications, Death, Expedite Discharge and Improve Quality of Life, Exercise Endurance and Capacity in Stroke Survivors With CoViD-19: A Clinical-Controlled Study
Background: Coronavirus (CoViD-19) positive stroke survivors (SSv) with comorbidities faces possibility for mortality. Study reports success of physiotherapy in CoViD-19 positive SSv with multiple comorbidities.
- Trial name
- NCT04471831
- Testing
- Rehabilitation exercise protocol
- Volunteers
- 30 people
- Sponsor
- University of Lagos, Nigeria
Corona Virus Infection
Clinical Characteristics and In-hospital Death of a Chilean COVID-19 Prospective Cohort
The investigators planned to examine a cohort of admitted patients at University of Chile Clinical Hospital with COVID-19 diagnosis.
- Trial name
- NCT04758039
- Where
- Chile
- Volunteers
- 395 people
- Sponsor
- University of Chile
Corona Virus Infection, Hepatitis
Does Hepatitis C Management Protect Egyptian Population Against Severe Corona Virus Disease-2019?
Modulation of the renin angiotensin system by the chronic hepatitis C virus treatment either by (Daclatasvir and Sofosbuvir), (Daclatasvir and Sofosbuvir plus Ribavirin), or (Ribavirin and Interferon) protocols could give an…
- Trial name
- NCT04757272
- Where
- Egypt
- Volunteers
- 2,106 people
- Sponsor
- Zagazig University
Corona Virus Infection, Pneumonia
Epidemiological and Demographic Data From 150 Patients Diagnosed With Coronavirus Disease 2019 Pneumonia
In this study, the investigator examined epidemiological and demographic characteristics, risk factors and 28-day mortality of patients admitted to the intensive care unit with the diagnosis of coronavirus disease 2019 pneumonia.
- Conditions
- Corona Virus Infection, Pneumonia, Acute Respiratory Failure
- Trial name
- NCT04430023
- Testing
- epidemiological and demographic characteristics
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital
Convalescence, Corona Virus Infection
Convalescent Plasma Therapy in Patients With COVID-19
Scientists and medical workers all around the world were running out of time to manage COVID-19. Several studies have been done to understand the disease and ultimately to find possible treatment.
- Conditions
- Convalescence, Corona Virus Infection, Plaque
- Trial name
- NCT04407208
- Testing
- Convalescent plasma
- Where
- Indonesia
- Volunteers
- 10 people
- Sponsor
- Biofarma
Covid19, Vitamin D Deficiency
High Dose Vitamin-D Substitution in Patients With COVID-19: a Randomized Controlled, Multi Center Study
The world is currently facing a pandemic with the coronavirus (SARS-CoV-2) which leads to the disease of COVID-19. Risk factors for a poor outcome of COVID-19 have so far been identified as older age and co-morbidity including…
- Conditions
- Covid19, Vitamin D Deficiency, Corona Virus Infection, ARDS
- Trial name
- VitCov (NCT04525820)
- Testing
- Single high dose vitamin D, Treatment as usual vitamin D
- Where
- 2 sites in Switzerland
- Volunteers
- 80 people
- Sponsor
- Prof. Dr. Jörg Leuppi
Covid19, Corona Virus Infection
Investigating the Involvement of ACE and Angiotensinogen Genes' Polymorphism Along With Other Thrombophilic Genotypes in Severe Forms of COVID-19 With/Without Thrombotic Events
An estimated 22% of the global population is at an increased risk of a severe form of COVID-19, while one in four coronavirus patients admitted to intensive care unit will develop a pulmonary embolism.
- Conditions
- Covid19, Corona Virus Infection, Thrombosis, ARDS
- Trial name
- iGenes-COVID19 (NCT04519398)
- Testing
- Complete thrombophilic profile testing by multiplex PCR
- Where
- Romania
- Volunteers
- 60 people
- Sponsor
- Grigore T. Popa University of Medicine and Pharmacy
COVID-19
Safety, Tolerability and PK of Ensovibep (MP0420 - a New Candidate With Potential for Treatment of COVID-19)
This study will investigate how ensovibep is distributed throughout the body, the safety and the tolerability of ensovibep in healthy volunteers
- Trial name
- NCT04870164
- Testing
- Ensovibep
- Where
- United Kingdom
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Molecular Partners AG
Coronavirus Disease 2019 (COVID-19), Respiratory Illness
BCG Vaccination to Protect Healthcare Workers Against COVID-19
Phase III, two-group multicentre, randomised controlled trial in up to 10 078 healthcare workers to determine if BCG vaccination reduces the incidence and severity of COVID-19 during the 2020 pandemic.
- Conditions
- Coronavirus Disease 2019 (COVID-19), Respiratory Illness, Corona Virus Infection, COVID-19
- Trial name
- BRACE (NCT04327206)
- Testing
- BCG Vaccine, 0.9%NaCl
- Where
- 36 sites in Australia, Brazil and 3 more
- Volunteers
- 6,828 people, healthy volunteers welcome
- Sponsor
- Murdoch Childrens Research Institute
Covid19, Treatment
Ezrin Peptide (HEP-1) for Treatment of Coronavirus Disease (COVID-19) Infection
Currently, SARS-CoV-2 the novel member of the corona virus family, affecting the world leading to COVID-19 disease. It can result life-threatening condition by developing severe acute respiratory distress syndrome (ARDS).
- Conditions
- Covid19, Treatment, Corona Virus Infection
- Trial name
- NCT04627233
- Testing
- Human Ezrin Peptide 1 (HEP1)
- Where
- Iran
- Volunteers
- 20 people
- Sponsor
- Shahid Beheshti University of Medical Sciences
Covid19
Anti COVID 19 Hyperimmune Intravenous Immunoglobulin (C-IVIG) Therapy for Severe COVID-19 Patients
Severe ill Patients will be enrolled in the study (n=310) after duly filled consent forms. Recipients will be divided into 2 group, each group contain 155 patients to compare Safety and efficacy of patients in Clinical Trial…
- Trial name
- NCT04891172
- Testing
- Anti COVID 19 Intravenous Immunoglobulin (C-IVIG)
- Where
- Pakistan
- Volunteers
- 310 people
- Sponsor
- Dow University of Health Sciences
Pneumonia, Viral, Corona Virus Infection
Enhanced Platelet Inhibition in Critically Ill Patients With COVID-19
This is a compassionate use, proof of concept, phase IIb, prospective, interventional, pilot study in which the investigators will evaluate the effects of compassionate-use treatment with IV tirofiban 25 mcg/kg, associated with…
- Conditions
- Pneumonia, Viral, Corona Virus Infection, Respiratory Failure, Embolism and Thrombosis
- Trial name
- PIC-19 (NCT04368377)
- Testing
- Tirofiban Injection, Clopidogrel, Acetylsalicylic acid
- Where
- Italy
- Volunteers
- 5 people
- Sponsor
- University of Milan
Multiple Myeloma, Covid19
COVID-19 Infection and Multiple Myeloma
Collect in an observational study the outcomes of COVID19 infection in MM patients across Europe.
- Conditions
- Multiple Myeloma, Covid19, Corona Virus Infection
- Trial name
- EMN-COVID (NCT04492371)
- Where
- 8 sites in Austria, Belgium and 6 more
- Volunteers
- 1,054 people
- Sponsor
- Stichting European Myeloma Network
COVID-19
CORONA Germany- Clinical Outcome and Risk in Hospitalized COVID-19 Patients - An Epidemiological Study From Germany
This is a multicenter, observational, prospective, epidemiological cohort study at 45 hospitals in Germany, all part of a German hospital network. All hospitalized patients tested positive for SARS-CoV-2 will be included.
- Trial name
- CORONA Germany (NCT04659187)
- Where
- 8 sites in Germany
- Volunteers
- 4,000 people
- Sponsor
- Asklepios proresearch
SARS-CoV-2 Acute Respiratory Disease, SARS-CoV-2 Sepsis
The Corona Study of Middle Norway
CUT COVID is a cohort study establised to collect information on patients hospitalized because or with infection by SARS-CoV-2. The cohort data includes clinical data and biological samples from multiple timepoints during…
- Conditions
- SARS-CoV-2 Acute Respiratory Disease, SARS-CoV-2 Sepsis, SARS CoV 2 Infection
- Trial name
- CUT COVID-19 (NCT05638178)
- Testing
- No intervention
- Where
- 5 sites in Norway
- Volunteers
- 223 people
- Sponsor
- St. Olavs Hospital
Covid19, Corona Virus Infection
Non-invasive Prognostication of COVID-19 Patients by Use of Biomarkers in Exhaled Breath Condensate
The main objective of this study is to assess if analysis of exhaled breath condensate (EBC) can provide useful prognostic markers for admission to the intensive care unit (ICU) due to acute respiratory insufficiency among…
- Trial name
- VTE-COVID-19 (NCT04598620)
- Where
- Denmark
- Volunteers
- 28 people
- Sponsor
- Inger Lise Gade
Corona Virus Infection, Acute Respiratory Distress Syndrome
Losartan for Patients With COVID-19 Not Requiring Hospitalization
This is a multi-center, double-blinded study of COVID-19 infected patients randomized 1:1 to daily losartan or placebo for 10 days or treatment failure (hospital admission).
- Conditions
- Corona Virus Infection, Acute Respiratory Distress Syndrome, SARS-CoV Infection
- Trial name
- NCT04311177
- Testing
- Losartan
- Where
- 4 sites in United States
- Volunteers
- 117 people
- Sponsor
- University of Minnesota
Covid19
COVID-19 Immunologic Antiviral Therapy With Omalizumab
To evaluate if omalizumab is effective in decreasing mortality in severe hospitalized COVID-19 cases.
- Trial name
- CIAO (NCT04720612)
- Testing
- Omalizumab
- Where
- 3 sites in Canada
- Volunteers
- 40 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Coronavirus as the Cause of Diseases Classified Elsewhere
CoV-ICU Score, Intensive Care Unit, SARS-CoV-2
In the course of COVID disease, some patients need intensive care treatment. We aim to find an answer to the question of whether the patient's CRP, ferritin, D-dimer, Oxygen Saturation, lymphocyte count, and body mass index can…
- Trial name
- NCT04383483
- Testing
- COVICU
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital