Clinical trials: Coronary; Ischemic
Coronary Ischemia
Pharmacologic Treatment of Myocardial Ischemia Detected by Intracoronary ECG
After PCI searching for target lesion ischemia with intracoronary ECG will be performed and if found it will be treated pharmacologically
- Trial name
- NCT03383393
- Testing
- Intracoronary bolus of adenosine (adenocor), Integrilin (eptifibatide) or nitroglyzerin (nitronal)
- Where
- Bulgaria
- Volunteers
- 60 people
- Sponsor
- Alexandrovska University Hospital
Type 2 Diabetes, Coronary Artery Disease
Study on the Prognosis and Effect of Anti-diabetic Drugs on Type-2 Diabetes Mellitus With Coronary Artery Disease
The purpose of this study is to explore the recurrence risk of cardiovascular events in patients with type 2 diabetes mellitus and coronary heart disease after different antidiabetic drug therapy (glipizide or metformin) by using…
- Trial name
- SPREADDIMCAD (NCT00513630)
- Testing
- Glipizide, Metformin
- Where
- China
- Volunteers
- 304 people
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Myocardial Infarction
Effect of Renin Angiotensin Aldosterone System Genetic Polymorphism on the Pharmacological Effect of Mineralocorticoid Receptor Antagonists in Patients With Myocardial Infarction
Early treatment of Myocardial Infarction patients with mineralocorticoid receptor antagonist with help reduces the incidence of cardiac remodeling and development into heart failure.
- Trial name
- NCT05873400
- Where
- Egypt
- Volunteers
- 102 people
- Sponsor
- Ain Shams University
Myocardial Infarction
Bone Marrow Stem Cell Mobilisation Therapy for Acute Myocardial Infarction (AMI)(REVIVAL-2)
The purpose of this study is to determine whether stem cell mobilization by granulocyte colony-stimulating factor (G-CSF) therapy in patients with acute myocardial infarction after successful mechanical reperfusion reduces…
- Trial name
- NCT00126100
- Testing
- G-CSF Granulocyte-Colony Stimulating Factor
- Where
- 2 sites in Germany
- Volunteers
- 114 people
- Sponsor
- Deutsches Herzzentrum Muenchen
Coronary Heart Disease (CHD)
Efficacy and Safety of MEDI6570 in Patients With a History of Myocardial Infarction
A Phase IIB Parallel group Study to Evaluate the Efficacy and Safety of MEDI6570 in Participants with a Prior Myocardial Infarction.
- Trial name
- GOLDILOX (NCT04610892)
- Testing
- MEDI6570
- Where
- 84 sites in United States, Australia and 9 more
- Volunteers
- 423 people
- Sponsor
- AstraZeneca
Atherosclerosis, Percutaneous Coronary Intervention
A Clinical Trial Comparing Cangrelor to Clopidogrel Standard Therapy in Subjects Who Require Percutaneous Coronary Intervention (PCI) (CHAMPION PHOENIX)
The study is designed to compare the efficacy and safety profile of cangrelor to standard of care in patients require percutaneous coronary intervention (PCI).
- Conditions
- Atherosclerosis, Percutaneous Coronary Intervention, Acute Coronary Syndrome
- Trial name
- CHAMPION (NCT01156571)
- Testing
- cangrelor P2Y12 (platelet) inhibitor, Clopidogrel - 300 or 600 mg (study arm), Clopidogrel 600 mg post cangrelor
- Where
- United States
- Volunteers
- 11,145 people
- Sponsor
- The Medicines Company
Circulatory Shock, Cardiovascular Shock
Physiologic Effect of Topical Nitroglycerin on Microcirculation Capacity in Patients With Circulatory Shock.
This is an open-label, single center, trial that will enroll up to 25 participants with circulatory shock after cardiac surgery.
- Trial name
- NCT05102734
- Testing
- Nitroglycerin Topical Product
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- University of Pennsylvania
Atrial Fibrillation, Ischemic Heart Disease
The New Pharmaceutical Composition Containing Botulinum Toxin to Treat Atrial Fibrillation
The aim of this prospective randomized double-blind study was to compare the efficacy of new pharmaceutical composition containing botulinum toxin injection in epicardial fat pads for preventing recurrences of atrial…
- Trial name
- NCT02982434
- Testing
- Pharmaceutical composition containing botulinum toxin, 0.9% normal saline, Coronary artery bypass grafting
- Where
- 2 sites in Russia
- Volunteers
- 180 people
- Sponsor
- Meshalkin Research Institute of Pathology of Circulation
Coronary Stenosis, Acute Coronary Syndrome
Coronary Plaque Geometry and Acute Coronary Syndromes
The aim of GEOMETRY study is to investigate the correlation between coronary plaque geometric modifications and lesion vulnerability in patients with suspected coronary artery disease referred for cardiac computed tomography…
- Conditions
- Coronary Stenosis, Acute Coronary Syndrome, Acute Myocardial Infarction, Atherosclerosis
- Trial name
- NCT03702764
- Testing
- CCTA
- Where
- Romania
- Volunteers
- 1,000 people
- Sponsor
- Cardio Med Medical Center
Coronary Atherosclerosis, Prevention of Heart Disease
CPR Training in 7th Grade Students
This is a prospective study of 7th grade students participating in the CPR Anytime® program. After consent, participants will be asked to complete the program with their parent(s)/legal guardian(s) and encouraged to include other…
- Trial name
- NCT00570609
- Testing
- CPR Anytime education
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Marna Rayl Greenberg
ST Elevation Myocardial Infarction
Relationship Between Left Ventricular Remodeling, Coronary Endothelial Function and Myocardial Fibrosis Using Positron Emission Tomography in Patients With ST-elevation Myocardial Infarction
Left ventricular remodeling is a common complication in patients with ST-elevation myocardial infarction (STEMI ) and may lead to heart failure.
- Trial name
- REMOD-TEP (NCT02789098)
- Testing
- (15)-O water positron emission tomography and Biomarkers
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Caen
Coronary Artery Disease
A Study of 123I-CMICE-013 Radiopharmaceutical in Healthy Volunteers
The need exists for alternatives to 99mTc based perfusion radiotracers for cardiac patient management. An alternative radiotracer, I123-CMICE-013, has been developed at the Canadian Molecular Imaging Center of Excellence (C-MICE)…
- Trial name
- CMICE (NCT01558362)
- Testing
- 123I-CMICE-013
- Where
- Canada
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Ottawa Heart Institute Research Corporation
Patent Foramen Ovale, Stroke
Evaluation of the STARFlex® Septal Closure System in Patients With a Stroke or TIA Due to the Possible Passage of a Clot of Unknown Origin Through a Patent Foramen Ovale (PFO)
The primary objective of the study is to determine whether the STARFlex® septal closure system will safely and effectively prevent a recurrent embolic stroke/transient ischemic attack (TIA) and mortality in patients with a PFO…
- Conditions
- Patent Foramen Ovale, Stroke, Ischemic Attack, Transient
- Trial name
- NCT00201461
- Testing
- STARFlex septal closure system, Best medical therapy
- Where
- United States
- Volunteers
- 900 people
- Sponsor
- NMT Medical
Coronary Disease
Conor Cobalt Chromium Reservoir Based Stent With Sirolimus Elution in Native Coronary Artery Lesions
The primary objective of this study is to evaluate the target lesion failure rate of the NEVO Sirolimus-eluting Coronary Stent System.
- Trial name
- NEVO RES-II (NCT00714883)
- Testing
- NEVO™ Sirolimus-eluting Coronary Stent System
- Where
- 2 sites in Germany, Latvia
- Volunteers
- 3 people
- Sponsor
- Cordis US Corp.
Coronary Arterial Disease (CAD)
To Determine the Difference in the Radiation Exposure, With Low Dose Protocols for Angiography
1. The patients suspected coronary artery disease or those needing an angiography as per the inclusion criteria would be included after a 2d echocardiography and treadmill test/ stress myocardial stress imaging (if indicated)…
- Trial name
- RADRED (NCT06602583)
- Testing
- Standard Dose Coronary angiography, New low dose angiography
- Where
- India
- Volunteers
- 60 people
- Sponsor
- Dr Bharat Singh Sambyal
Diabetes, Cardiovascular Disease
Associations Between Diabetes Care and Haptoglobin Genotype On outComes
The ADHOC Cohort comprised 3044 DM individuals, treated in 47 CHS primary care clinics, that underwent haptoglobin genotyping between 2 march, 2005 and 26 September 2006.
- Conditions
- Diabetes, Cardiovascular Disease, Myocardial Infarction, Stroke
- Trial name
- ADHOC (NCT00872456)
- Volunteers
- 3,054 people
- Sponsor
- Clalit Health Services
Coronary Artery Disease, Stable Angina
BMX Alpha Registry: a Post-market Registry of the BioMatrix Alpha TM
Prospective, multi-center, registry designed to enrol up to 2,000 patients in up to 35 International centers. All patients will receive a BioMatrix AlphaTM stent as per clinical practice and will be followed for 2 years for data…
- Conditions
- Coronary Artery Disease, Stable Angina, Ischemia, Acute Coronary Syndrome
- Trial name
- NCT02871622
- Testing
- BioMatrix AlphaTM
- Where
- United Kingdom
- Volunteers
- 2,000 people
- Sponsor
- Biosensors Europe SA
Coronary Artery Disease, Arteriosclerosis
Associations Between Diabetes, Arterial Stiffness and Fibulin-1 in Patients Undergoing Heart- and Vascular Surgery?
Diabetes Mellitus (DM) is frequently appearing in patients with cardiovascular disease and these patients, as a consequence herby, has a lesser prognosis. DM is often related to increased arterial stiffness and hypertension.
- Conditions
- Coronary Artery Disease, Arteriosclerosis, Carotid Stenosis, Thrombosis
- Trial name
- NCT01106573
- Where
- Denmark
- Volunteers
- 1,400 people
- Sponsor
- Odense University Hospital
Myocardial Infarction, Ischemic Heart Disease
Half-Dose Radiopharmaceutical in Wide Beam Reconstruction
This study is recruiting patients already scheduled for a single photon emission computed tomography myocardial perfusion imaging (SPECT-MPI) test.
- Trial name
- REGA-1102 (NCT01499654)
- Testing
- Half-dose of the Tc99-m sestamibi (Cardiolite)
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- Edwin Wu
Myocardial Infarction, Acute
Prognostic Value of Surem TRAF3IP2 Level in Patients With Acute Myocardial Infarction
To evaluate the prognostic value of surem TRAF3IP2 levels in patients with acute myocardial infarction
- Trial name
- NCT06038994
- Testing
- No intervention
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Nanjing Medical University
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