Clinical trials: Coronary Angioplasty
Ischemic Heart Disease, Coronary Atherosclerosis
T-provisional Stenting vs Mini-Crush in Chronic Total Occlusions (CTO)
The aim is to compare the results of using T-provisional and Mini-Crush stenting techniques in patients with bifurcation lesions in the CTO segment.
- Conditions
- Ischemic Heart Disease, Coronary Atherosclerosis, Coronary Artery Disease, Coronary Artery Stenosis
- Trial name
- NCT02708329
- Testing
- T-provisional stenting, Mini-crush stenting, CTO coronary angioplasty
- Where
- Russia
- Volunteers
- 146 people
- Sponsor
- Meshalkin Research Institute of Pathology of Circulation
Coronary Artery Disease
Efficacy and Safety of Paclitaxel-eluting Balloon for Treatment of Lesions in Native Small Coronary Arteries
The purpose of this study is to evaluate the efficacy and safety of paclitaxel-eluting balloon (SeQuent® Please) for treatment of lesions in native small coronary arteries.
- Trial name
- NCT01903902
- Testing
- SeQuent® Please Drug-eluting balloon
- Where
- South Korea
- Volunteers
- 1,000 people
- Sponsor
- Gachon University Gil Medical Center
Coronary Stenosis, Coronary Thrombosis
Monitoring Response to Antiplatelet Therapy
Antiplatelet therapy plays a key role in the prevention of complications related to coronary angioplasty and stenting (PCI) including procedure related myocardial damage.
- Conditions
- Coronary Stenosis, Coronary Thrombosis, Angioplasty, Balloon
- Trial name
- NCT00327041
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- NHS Greater Glasgow and Clyde
Chronic Limb Threatening Ischemia
Laser Atherectomy and Sirolimus-eluting Balloon Angioplasty for CLTI
Peripheral arterial disease (PAD) is a widespread pathology affecting over 200 million adults globally and is primarily caused by atherosclerosis.
- Trial name
- LASER-S (NCT07858539)
- Testing
- Laser atherectomy followed by Sirolimus-eluting balloon angioplasty of femoropopliteal or infrapopliteal or both arterial stenosis or occlusions
- Where
- Greece
- Volunteers
- 55 people
- Sponsor
- Attikon Hospital
Myocardial Ischemia, Coronary Arterial Disease (CAD)
Effectiveness of Inspiratory Muscle Training for People With Ischemic Heart Disease Revascularized by Percutaneous Transluminal Coronary Angioplasty.
Myocardial Ischemia (MI) consists of the narrowing of the internal lumen of the arteries that perfuse the heart. As the section of the artery decreases, so does the blood flow and therefore the supply of oxygen to the myocardium…
- Trial name
- CARDIOINSPIRE (NCT06681740)
- Testing
- Inspiratory muscle training
- Where
- Spain
- Volunteers
- 72 people
- Sponsor
- University of Cadiz
Acute Coronary Syndromes
Does Optical Coherence Tomography Optimise Results of Stenting
Optical Coherence Tomography (OCT) is a recent imaging modality that yields cross-sectional images with a resolution 10 times greater than that of intravascular ultrasound (IVUS).
- Trial name
- DOCTORS (NCT01743274)
- Testing
- OCT
- Where
- 8 sites in France
- Volunteers
- 240 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Coronary Disease, Coronary Artery Disease
SPIRIT V: A Clinical Evaluation of the XIENCE V® Everolimus Eluting Coronary Stent System in the Treatment of Patients With de Novo Coronary Artery Lesions (Diabetic Sub-Study)
The purpose of this Clinical Evaluation is a continuation in the assessment of the performance of the XIENCE V® Everolimus Eluting Coronary Stent System (XIENCE V® EECSS) in the treatment of patients with de novo coronary artery…
- Conditions
- Coronary Disease, Coronary Artery Disease, Coronary Restenosis
- Trial name
- NCT01171820
- Testing
- TAXUS® Liberté™, XIENCE V® EECSS
- Where
- 28 sites in Austria, France and 9 more
- Volunteers
- 324 people
- Sponsor
- Abbott Medical Devices
Percutaneous Coronary Angioplasty
Angiographic and IVUS Follow-up After Simultaneously Implanted Different Drug-eluting Stents in Same Individuals (AIFSIDDES)
The safety and efficacy of drug-eluting stents (DES) with a biocompatible polymer have been demonstrated in randomized clinical trials as well as in real world practice.
- Trial name
- NCT01382043
- Where
- China
- Volunteers
- 48 people
- Sponsor
- Liuhuaqiao Hospital
Femoral Artery Stenosis, Popliteal Artery Stenosis
DKutting Balloon Versus Chocolate Balloon to Treat Femoral and Popliteal Artery Stenosis
A Multicenter, Prospective, Randomized Controlled Trial to Evaluate the Efficacy and Safety of DKutting Balloon Versus Chocolate Balloon in the Treatment of Femoral and Popliteal Artery Stenosis
- Trial name
- DELTA (NCT05608655)
- Testing
- DKutting LL balloon, Chocolate balloon
- Where
- 14 sites in China
- Volunteers
- 188 people
- Sponsor
- DK Medical Technology (Suzhou) Co., Ltd.
Coronary Artery Disease
STRATEGY for Left Main Coronary Bifurcation Lesion II
In patients with unprotected left main (LM) true bifurcation lesion (cohort A), elective 2-stent strategy is superior to provisional strategy at preventing the occurrence of 12-month target lesion failure after percutaneous…
- Trial name
- STRATEGY-II (NCT01798433)
- Testing
- One stent technique alone, One stent technique + Elective FKB, Provisional approach
- Where
- South Korea
- Volunteers
- 200 people
- Sponsor
- Samsung Medical Center
Myocardial Infarction, Angioplasty, Transluminal, Percutaneous Coronary
Strategies of Revascularization in Patients With ST-segment Elevation Myocardial Infarction (STEMI) and Multivessel Disease
Multivessel disease has been reported to occur between 40 and 60% of patients with ST-segment elevation myocardial infarction (STEMI) and has been associated to a worse prognosis.
- Conditions
- Myocardial Infarction, Angioplasty, Transluminal, Percutaneous Coronary, Echocardiography, Stress
- Trial name
- CROSS-AMI (NCT01179126)
- Testing
- complete multivessel revascularization, stress echocardiography and revascularization if required
- Where
- Spain
- Volunteers
- 400 people
- Sponsor
- Complexo Hospitalario Universitario de A Coruña
Angioplasty, Transluminal, Percutaneous Coronary
Study of Tirofiban Administration in Patients With Aspirin and or Clopidogrel Resistance
This study will evaluate whether adding tirofiban, administered at high bolus dose on top of aspirin and clopidogrel will lead to a lower rate of periprocedural myocardial infarction after percutaneous coronary intervention in…
- Trial name
- 3T/2R (NCT00398463)
- Testing
- Tirofiban
- Where
- Italy
- Volunteers
- 263 people
- Sponsor
- Università degli Studi di Ferrara
Acute Myocardial Infarction
Optical Coherence Tomography Assessment of Gender diVersity In Primary Angioplasty: The OCTAVIA Trial
Recent studies suggest important gender differences in the pathophysiology and prognosis of ST-segment elevation myocardial infarction (STEMI).
- Trial name
- OCTAVIA (NCT02577965)
- Testing
- Percutaneous Coronary Intervention, XIENCE PRIME Everolimus Eluting Coronary Stent System
- Volunteers
- 140 people
- Sponsor
- A.O. Ospedale Papa Giovanni XXIII
Coronary Artery Disease, Angioplasty, Balloon
Drug-Eluting Balloon Registry in Routine Clinical Practice
The purpose of this study is to evaluate long-term effectiveness and safety of patients with coronary disease treated with drug eluting balloon in real world practice.
- Trial name
- IRIS DEB (NCT02038660)
- Testing
- Balloon angioplasty
- Where
- 9 sites in South Korea
- Volunteers
- 1,500 people
- Sponsor
- Seung-Jung Park
Coronary Artery Disease, Diabete Type 2
DCB for CAD With Type 2 Diabetes
Patients with coronary artery disease (CAD) and type 2 diabetes mellitus (T2DM) often present with diffuse, complex lesions and a higher risk of in-stent restenosis after PCI.
- Trial name
- DCBinT2DM (NCT07009938)
- Testing
- Drug-Coated Balloon (DCB), Drug-Eluting Stent (DES) implantation
- Where
- 6 sites in China
- Volunteers
- 1,000 people
- Sponsor
- Shanghai 10th People's Hospital
Cardiovascular Diseases
Investigating the Effects of Dietary Nitrate on Vascular Function, Platelet Reactivity and Restenosis in Stable Angina
The mainstay treatment for reducing the symptoms of angina and long-term risk of heart attacks in patients with heart disease is stent implantation in the diseased coronary artery.
- Trial name
- NITRATE-OCT (NCT02529189)
- Testing
- Beetroot Juice
- Where
- United Kingdom
- Volunteers
- 300 people
- Sponsor
- Queen Mary University of London
Myocardial Infarction, Acute Coronary Syndrome
Impact on Public HEalth of a Network in Acute Myocardial Infarction Care
This is a multicenter retrospective observational study with STEMI (ST Elevation Myocardial Infarction) patients who have been treated in the northern Galician Hospitals.
- Trial name
- iPHENAMIC (NCT02501070)
- Where
- Spain
- Volunteers
- 5,937 people
- Sponsor
- Complexo Hospitalario Universitario de A Coruña
ST-Elevation Myocardial Infarction
A Safety/Efficacy Study of Intracoronary Integrilin to Improve Balloon Angioplasty Outcomes for the Treatment of Heart Attacks
The main purpose of this research study is to try to improve the results of the standard treatment for heart attacks. Normally, heart attack patients get a fast dose and a slow dose of eptifibatide in the emergency room, shortly…
- Trial name
- IC TITAN (NCT00719914)
- Testing
- eptifibatide, normal saline
- Where
- 3 sites in United States
- Volunteers
- 31 people
- Sponsor
- Brigham and Women's Hospital
Oxidative Stress, Coronary Artery Disease
Efficacy of Pioglitazone on Myocardial Function in Patients Undergoing Coronary Stent Implantation.
The purpose of this study is to determine the effects of pioglitazone, once daily (QD), on heart functioning before, during and after stent implantation.
- Conditions
- Oxidative Stress, Coronary Artery Disease, Type 2 Diabetes
- Trial name
- NCT00771004
- Testing
- Pioglitazone
- Where
- 7 sites in Germany
- Volunteers
- 63 people
- Sponsor
- Takeda
Peripheral Arterial Occlusive Disease, Bypass Complication
The SIR-POBA Bypass Trial
The goal of this clinical trial is to compare plain old balloon angioplasty with sirolimus-coated balloon angioplasty in patients with an infrainguinal venous bypass stenosis.
- Conditions
- Peripheral Arterial Occlusive Disease, Bypass Complication, Femoropopliteal Artery Occlusion, Femoropopliteal Stenosis
- Trial name
- NCT06056193
- Testing
- Balloon Angioplasty
- Where
- Austria
- Sponsor
- Paracelsus Medical University