Clinical trials: Coronary Angioplasty
Atherosclerosis
Evaluation of the Neointimal Healing by OCT of the Tapered DES Biomime Morph (TAPER-I Study)
The long and very long stents, although they represent a greater navigability challenge, especially in tortuous and calcified coronary arteries, they have the advantage of providing shorter procedural time, with less contrast…
- Trial name
- TAPER-I (NCT04805619)
- Testing
- Biomime Morph, a tapered drug eluting stent (DES) with hybrid design
- Where
- Brazil
- Volunteers
- 35 people
- Sponsor
- University of Sao Paulo General Hospital
Patient Adherence
Efficacy Of An Education Plan And Adherence Follow-Up To The Exercise In Patients With Angioplasty And Stent Coronary
Cardiovascular diseases are a leading cause of death worldwide. Some of the risk factors that have been identified are considered as be non-modifiable and modifiable.
- Trial name
- NCT03231631
- Testing
- Education plan and adherence to exercise
- Where
- Colombia
- Volunteers
- 71 people
- Sponsor
- Clínica de Occidente S.A
Nephropathy
A Randomized Trial of Rosuvastatin in Elective Angioplasty to Prevent Contrast-induced Nephropathy (CLEAR-CIN).
The investigators analyzed the HMG-CoA reductase inhibitor, rosuvastatin, for the prevention of contrast-medium-induced nephropathy in patients undergoing primary angioplasty.
- Trial name
- CLEAR-CIN (NCT02737319)
- Testing
- Rosuvastatin
- Where
- Brazil
- Volunteers
- 493 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Ischemic Heart Disease, Stenotic Coronary Lesion
RESOLUTE ONYX China Single Arm Study
It is a single arm clinical evaluation of safety and efficacy of the Medtronic Resolute Onyx™ zotarolimus-eluting coronary stent system in subjects who are eligible for percutaneous transluminal coronary angioplasty (PTCA) in de…
- Conditions
- Ischemic Heart Disease, Stenotic Coronary Lesion, Cardiovascular Diseases, Arteriosclerosis
- Trial name
- NCT03471845
- Testing
- Resolute Onyx™ Zotarolimus-Eluting Coronary Stent System
- Where
- China
- Volunteers
- 591 people
- Sponsor
- Medtronic Vascular
Symptomatic Intracranial Atherosclerotic Stenosis
Drug-Coated Balloon vs Aggressive Medical Management for High-Risk Symptomatic Intracranial Atherosclerotic Stenosis
DR.BEYOND-2 is an investigator-initiated, prospective, multicenter, randomized, open-label, blinded-endpoint, parallel-group clinical trial designed to evaluate the efficacy and safety of drug-coated balloon (DCB) angioplasty…
- Trial name
- DRBEYOND2 (NCT07830277)
- Testing
- Drug-Coated Balloon Angioplasty, Aggressive Medical Management
- Where
- 2 sites in China
- Volunteers
- 570 people
- Sponsor
- Beijing Tiantan Hospital
Obstructive Coronary Artery Disease, Obstructive Peripheral Artery Disease
Catheter-Based Treatment of Cardiovascular Disease
This study offers catheter-based treatment of heart or artery disease. This protocol permits treatment of patients with cardiovascular diseases who may not be eligible to participate in current research protocols.
- Conditions
- Obstructive Coronary Artery Disease, Obstructive Peripheral Artery Disease, Structural Heart Disease
- Trial name
- NCT00380016
- Testing
- Percutaneous Transluminal Angioplasty
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Acute Myocardial Infarction
FATA: Randomized Study on Facilitated Angioplasty With Tirofiban or Abciximab
The elective("standard of care") treatment of ST - elevation acute myocardial infarction (STEMI) currently consists of primary angioplasty with stent implantation during administration of Abciximab, a inhibitor of GP IIb/IIIa…
- Trial name
- FATA (NCT00383136)
- Testing
- tirofiban high-bolus dose regimen, Abciximab
- Where
- 6 sites in Italy
- Volunteers
- 692 people
- Sponsor
- University of Bologna
Femoropopliteal Arterial Stenosis
Effect of Inflation on the Angiographic Result After Balloon Angioplasty in the Femoropopliteal Segment
Percutaneous angioplasty with balloon dilation is the method of choice for the treatment of most femoropopliteal artery lesions.
- Trial name
- Balloon-angio (NCT03428204)
- Testing
- Balloon dilation during 180 seconds, Balloon dilation during 300 seconds
- Where
- Belgium
- Volunteers
- 200 people
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Coronary Disease
Safety and Efficacy Study of the DANUBIO Paclitaxel Eluting Balloon in Side Branches of de Novo Bifurcation Lesions (DEBSIDE)
The purpose of this study is to assess the safety and efficacy of the Danubio Paclitaxel Eluting Balloon for the treatment of side branches of de novo bifurcation lesions in native coronary arteries.
- Trial name
- DEBSIDE (NCT01485081)
- Testing
- Danubio paclitaxel-eluting balloon
- Where
- 7 sites in France
- Volunteers
- 52 people
- Sponsor
- MINVASYS
In-stent Restenosis
Target Vessel Failure After Laser Assisted Percutaneous Angioplasty Versus Balloon-based Treatment for Drug Eluting In-stent Restenosis
Stent restenosis (ISR) is an increasingly common problem; in fact, approximately 10% of coronary angioplasty procedures involve the treatment of a previously implanted stent.
- Trial name
- SONIC (NCT07382154)
- Where
- Italy
- Volunteers
- 1,260 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Peripheral Artery Disease, Atherosclerosis
Sirolimus Coated Balloon Versus Standard Balloon for SFA and Popliteal Artery Disease
This study aims to conduct a randomized, double blind, randomised controlled multicentre trial of sirolimus drug coated balloon versus standard percutaneous transluminal angioplasty for the treatment of superficial and popliteal…
- Conditions
- Peripheral Artery Disease, Atherosclerosis, Arterial Disease
- Trial name
- FUTURE-SFA (NCT04511234)
- Testing
- MagicTouch PTA sirolimus drug coated balloon (DCB), POBA standard balloon
- Where
- 20 sites in Singapore, Taiwan and 1 more
- Volunteers
- 279 people
- Sponsor
- Concept Medical Inc.
Stenosis
RCT of the Cutting Balloon Versus a High Pressure Balloon for the Treatment of Arteriovenous Fistula Stenoses
The proposed study will investigate the efficacy of the peripheral cutting balloon (PBC) compared to the high pressure balloon in dilating venous stenosis in hemodialysis fistulas. 2.
- Trial name
- NCT00543348
- Testing
- CUTTING BALLOON ANGIOPLASTY, Balloon angioplasty
- Where
- United States
- Sponsor
- Henry Ford Health System
Angina, Unstable, Angioplasty, Transluminal, Percutaneous Coronary
A Study Evaluating the Efficacy and Safety of Abciximab, an Anti-Platelet Therapy, in Patients With Unstable Angina Not Responding to Standard Medical Therapy Who Are Eligible for Coronary Angioplasty
The purpose of this study is to evaluate the safety and efficacy of abciximab, an anti-platelet therapy, versus placebo in patients with unstable angina who are not responding to standard medical therapy and who are eligible for…
- Trial name
- NCT00269906
- Testing
- Abciximab
- Volunteers
- 1,265 people
- Sponsor
- Centocor, Inc.
Coronary Artery Disease
OCT- Versus Angiography-guided Paclitaxel Drug-Coated Balloon Angioplasty in De Novo Coronary Artery
OCT allows precise evaluation of intimal injury after lesion preparation and may improve the acute results and long-term outcomes after paclitaxel drug-coated balloon angioplasty.
- Trial name
- NCT04276389
- Testing
- OCT-guided paclitaxel drug-coated balloon angioplasty, Angiography-guided paclitaxel drug-coated balloon angioplasty
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Beijing Anzhen Hospital
Atherosclerosis
Study Comparing Legflow Versus Bare Balloon Angioplasty for Treatment of Atherosclerotic Disease
A randomized multicentric study for endovascular treatment of patients with obstructive disease in the SFA (superficial femoral artery) and in the popliteal artery.
- Trial name
- NCT02710656
- Testing
- Legflow® balloon, Standard PTA
- Where
- 9 sites in Belgium, France and 1 more
- Volunteers
- 130 people
- Sponsor
- Cardionovum GmbH
Myocardial Infarction
Post Conditioning in PCI for Acute ST Elevation Myocardial Infarction
The purpose of this trial is to compare post-conditioning to standard angioplasty (50/50 chance) in patients who present with an acute heart attack and are taken directly for an angioplasty procedure.
- Trial name
- NCT00334373
- Testing
- Post conditioning
- Where
- Canada
- Volunteers
- 102 people
- Sponsor
- University of Calgary
Coronary Artery Disease
The Intra-Drug Eluting Stent (DES) Restenosis Study
A Prospective, Randomized, Multi-Center Comparison of the Cypher Select™ Sirolimus-Eluting Stent and Balloon Re-Angioplasty for Treatment of Patients with Intra-Des Restenosis.
- Trial name
- CRISTAL (NCT00323895)
- Testing
- drug-eluting stent and balloon angioplasty, drug-eluting stent
- Where
- 2 sites in France
- Volunteers
- 320 people
- Sponsor
- Cordis US Corp.
Radial Artery Spasm
Nitrate Use to Obtain Radial Spasm Embarrassment (NURSE - TTS Trial)
Transradial cardiac catheterization and percutaneous coronary intervention are increasingly being performed worldwide in elective and emergency procedures, with many centres adopting the transradial route as their first choice of…
- Trial name
- NURSE-TTS (NCT04766151)
- Testing
- Transdermal glyceryl trinitrate 10mg patches
- Where
- Greece
- Volunteers
- 150 people
- Sponsor
- 424 General Military Hospital
Coronary Disease, Coronary Artery Disease
EXecutive RCT: Evaluating XIENCE V® in a Multi Vessel Disease
The purpose of this two part study is the assessment of the performance of the XIENCE V® Everolimus Eluting Coronary Stent System (XIENCE V® EECSS) in the treatment of the specific setting of patients with Multi-Vessel Coronary…
- Conditions
- Coronary Disease, Coronary Artery Disease, Coronary Artery Stenosis, Coronary Artery Restenosis
- Trial name
- EXecutive (NCT00531011)
- Testing
- XIENCE V® Everolimus Eluting Coronary Stent System, TAXUS® Liberté™ Paclitaxel Eluting Coronary Stent System
- Where
- 24 sites in Italy
- Volunteers
- 200 people
- Sponsor
- Abbott Medical Devices
Acute Myocardial Infarction
Phase 1 Study of Potential Anti-Inflammatory Effects of Glucose Control During Acute Myocardial Infarction.
The purpose of this study is to determine if intense control of high glucose levels in patients treated with angioplasty for heart attack has anti-inflammatory and anti-thrombotic effects.
- Trial name
- NCT00209144
- Testing
- Intensive insulin therapy
- Where
- 2 sites in United States
- Volunteers
- 58 people
- Sponsor
- Emory University