Clinical trials: Coronary Arterioscleroses
Coronary Artery Disease, Coronary Artery Bypass Grafting
CCTA-Based vs CAG-Based CABG: A Multicenter Pragmatic Non-Inferiority Trial
The goal of this clinical trial is to find out if using a non-invasive heart scan (called coronary computed tomography angiography, or CCTA) to plan coronary artery bypass grafting (CABG) works as well as the standard invasive…
- Conditions
- Coronary Artery Disease, Coronary Artery Bypass Grafting, Coronary Computed Tomography Angiography, Coronary Angiography (CAG)
- Trial name
- CtaCAB (NCT07769008)
- Testing
- CCTA-based CABG, CAG-based CABG
- Where
- China
- Volunteers
- 826 people
- Sponsor
- Ruijin Hospital
Ischaemic Heart Disease
Motion and IntraCoronary Ecg Ischemia Development Study (MICE)
The concept of the "ischemic cascade" is generally accepted hypothesis, according to which whenever ischemia of the myocardium occurs there is a consequence of events, that always occur in a given order - diastolic dysfunction…
- Trial name
- MICE (NCT04061525)
- Testing
- Percutaneous coronary intervention with FFR measurement and intracoronary ECG registration
- Where
- Bulgaria
- Volunteers
- 30 people
- Sponsor
- University National Heart Hospital
Coronary Heart Disease
Smartphone Based Tele-rehabilitation on Functional Capacity and Sleep Quality Among Coronary Heart Disease Patients.
To determine the effectiveness of smartphone based tele-rehabilitation on functional capacity and sleep quality among coronary heart disease patients.
- Trial name
- NCT06548425
- Testing
- Smart Phone Based Cardiac Telerehabilitation, Center based cardiac Rehabilitation
- Where
- Pakistan
- Volunteers
- 38 people
- Sponsor
- Riphah International University
Coronary Heart Disease (CHD), Heart Failure
Community Exercise Treating Effect on Cardiopulmonary Disease Patients
The goal of this clinical trial is to learn if community-based exercise training can benefit patients aged 18 to 85 with diminished cardiovascular and pulmonary function.
- Conditions
- Coronary Heart Disease (CHD), Heart Failure, Cardiomyopathy, COPD
- Trial name
- NCT07154355
- Testing
- community-based exercise training
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Guangdong Provincial People's Hospital
Dyslipidemia, Coronary Heart Disease
Observational Study to Estimate the Rates of Outcomes in Patients Undergoing Percutaneous Coronary Intervention (PCI) With Drug Eluting Stent (DES) Implantation Who Take Statins
To estimate the rates of percutaneous coronary intervention (PCI) outcomes in patients after drug-eluting stents implantation who take statins.
- Trial name
- OPTIMA (NCT01047176)
- Where
- Russia
- Volunteers
- 602 people
- Sponsor
- AstraZeneca
Platelet Dysfunction Due to Drugs
The Effects of loW Dose tIcagrelor on Platelet Function Testing in Patients With Stable Coronary arTery Disease
This study aims to assess the effects of low dose ticagrelor on platelet function testing in patients with stable coronary artery disease.
- Trial name
- TWIST (NCT04206176)
- Testing
- Ticagrelor
- Where
- Trinidad and Tobago
- Volunteers
- 25 people
- Sponsor
- The University of The West Indies
Angina Pectoris, Coronary Artery Disease
Effects of Integrated Treatment by Traditional Chinese and Western Medicine in Reducing Cardiovascular Events
Compared with standardized western medical drug therapy, this study is mainly about whether the combination of standardized western medical drug therapy and Chinese medical continued treatment, can further decrease the rate of…
- Conditions
- Angina Pectoris, Coronary Artery Disease, Coronary Disease, Heart Disease
- Trial name
- NCT01715376
- Where
- China
- Volunteers
- 1,042 people, healthy volunteers welcome
- Sponsor
- Changchun University of Chinese Medicine
Acute Coronary Syndrome
Impact of a Digital Solution (CardiCare™) on Cardiorespiratory Fitness Improvement in Patients Discharged From a Phase 2 Cardiac Rehabilitation Following an Acute Coronary Syndrome
Coronary heart disease is a partial inability of the coronary arteries to supply the heart muscle due to their narrowing. There is angina and myocardial infarction.
- Trial name
- NCT04294940
- Testing
- Wear an actigraph, Use the mobile application CardiCare™ and wear an actigraph
- Where
- 10 sites in France, Italy and 2 more
- Sponsor
- Ad scientiam
Stroke, Ischemic
BEACON-AA: Apixaban With or Without Clopidogrel in Stroke Patients With Atrial Fibrillation and Cerebral Atherosclerosis
This trial aims to compare the safety and efficacy of apixaban alone versus apixaban combined with clopidogrel in patients with acute ischemic stroke associated with non-valvular atrial fibrillation and concomitant symptomatic…
- Conditions
- Stroke, Ischemic, Atrial Fibrillation, Intracrnaial Arterioscelrosis
- Trial name
- NCT07237308
- Testing
- Apixaban, Clopidogrel
- Where
- South Korea
- Volunteers
- 586 people
- Sponsor
- Yonsei University
Coronary Disease
Interactive Education of Patients With Coronary Heart Disease
Coronary Heart Diseases are responsible for a high number of deaths in Germany. To determine the risk factors secondary prevention is of great importance.
- Trial name
- INSERT (NCT02185391)
- Testing
- Audience Response System, Telephone interview
- Where
- Germany
- Volunteers
- 260 people
- Sponsor
- Paracelsus Harz Clinic Bad Suderode.
Non-ST Elevation Myocardial Infarction
Effect of the Interleukin-6 Receptor Antagonist Tocilizumab in Non-ST Elevation Myocardial Infarction
Acute coronary syndromes (ACS) are still associated with high morbidity and mortality, despite several improvements in their management.
- Trial name
- NCT01491074
- Testing
- Tocilizumab 280 mg, NaCl 0.9% 100 ml
- Where
- 2 sites in Norway
- Volunteers
- 120 people
- Sponsor
- Oslo University Hospital
Acute Coronary Syndrome, Depression
Comparison of Depression Interventions After Acute Coronary Syndrome
Patients will be consented and screened within 2 to 6 months of the index ACS. Patients who have elevated depression (BDI>=15 or BDI>=10 assessed twice over two week period) and who continue to meet all of the trial's eligibility…
- Trial name
- CODIACS (NCT01032018)
- Testing
- Problem Solving Therapy, Sertraline, citalopram, or bupropion, Standard care
- Where
- 5 sites in United States
- Volunteers
- 150 people
- Sponsor
- Columbia University
Cardiac Rehab, Coronary Artery Disease
Effects of Personalized Cardiac Rehabilitation on miRNAs and Biochemical Biomarkers in Patients With Coronary Artery Disease
This prospective interventional study aims to investigate changes in specific microRNAs (miRNAs) and biochemical biomarkers following a personalized cardiac rehabilitation program in patients with coronary artery disease.
- Trial name
- NCT07841847
- Testing
- Personalized Cardiac Rehabilitation Program
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people
- Sponsor
- Kutahya Health Sciences University
Coronary Heart Disease
Prospective Evaluation of Prognosis of Pci Patients Using Network Data in SHengjing Hospital
Coronary heart disease (CHD) has a serious health threaten to population. PCI is a well-proved measure in CHD management. However, the knowledge about the real-life PCI use and how evidence-based therapies in routine clinical…
- Trial name
- P-PUSH (NCT02667548)
- Testing
- PCI
- Volunteers
- 7,000 people
- Sponsor
- Shengjing Hospital
Coronary Artery Disease
Physicians International Coronary Computed Tomography Angiography (CCTA) Utilization Registry
This protocol describes an observational study whose goal is to collect de-identified Coronary CT Angiography (CCTA) acquisition factors and interpretations (findings) from several hundred U.S.
- Trial name
- BIGPICTURE (NCT00932958)
- Where
- United States
- Volunteers
- 6,000 people
- Sponsor
- MDDX LLC
Periodontal Diseases
DKK-3 rs11544814 and CFH rs10737680 Polymorphism and Protein Levels With Non Surgical Periodontal Therapy in Periodontitis Patients With and Without CAD
Untreated periodontal infection may result in transient bacteremia and toxaemia which may be the cause of adverse systemic events, leading to various systemic disorders.
- Trial name
- NCT05828368
- Testing
- Non surgical periodontal therapy
- Where
- 2 sites in India
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Meenakshi Ammal Dental College and Hospital
Coronary Artery Disease
The Effect of Video Education on Pain, Anxiety and Knowledge Levels of Coronary Bypass Graft Surgery Patients
The aim of this research to examine the effectiveness of video-education on pain, anxiety, and knowledge levels on adult patients undergoing coronary artery bypass graft surgery.
- Trial name
- NCT06174090
- Testing
- Coronary bypass graft surgery video education
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people
- Sponsor
- Baskent University
Angina Pectoris
CT Perfusion Added to CT Angiography
Background In the differential diagnosis of unstable angina versus non-anginal chest pain, an exercise test is often the modality of choice for further investigation.
- Trial name
- PERFeCT (NCT02773615)
- Testing
- Cardiac computed tomography
- Where
- Belgium
- Volunteers
- 200 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Myocardial Ischemia, Myocardial Viability
Assessment of Lesion-Associated Myocardial Ischemia Based on Fusion Coronary CT Imaging
The aim of the Fused-Heart study is to investigate the impact of a coronary artery stenosis on myocardial function and viability, based on advanced fusion imaging techniques derived from CCTA.
- Conditions
- Myocardial Ischemia, Myocardial Viability, Coronary Stenosis, Vulnerable Coronary Plaques
- Trial name
- FUSE-HEART (NCT04680689)
- Testing
- 128 Multislice CT coronary angiography, 2D Cardiac Transthoracic Echocardiography, Laboratory Blood tests
- Where
- Romania
- Volunteers
- 100 people
- Sponsor
- Cardio Med Medical Center
Heart Failure, Myocardial Infarction
Combined CABG and Stem-Cell Transplantation for Heart Failure
This is a prospective double blind trial of intraoperative transmyocardial bone marrow-derived mesenchymal cell transplantation vs placebo in patients with low left ventricular ejection fraction scheduled to coronary bypass…
- Conditions
- Heart Failure, Myocardial Infarction, Coronary Artery Disease
- Trial name
- NCT00418418
- Testing
- Coronary bypass operation, Bone marrow aspiration (crista iliaca), Intramyocardial mesenchymal stem cell transplantation
- Where
- Finland
- Volunteers
- 60 people
- Sponsor
- University of Helsinki
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