Clinical trials: Coronary Arterioscleroses
Myocardial Ischemic Reperfusion Injury, End Stage Heart Disease
Remote Ischemic Preconditioning With Postconditioning in Heart Transplantation Surgery
The purpose of this study is to determine whether remote ischemic preconditioning with postconditioning (RIPC+RIPostC) reduces myocardial injury and improves clinical outcomes in heart transplantation surgery.
- Conditions
- Myocardial Ischemic Reperfusion Injury, End Stage Heart Disease, Heart Failure, Cardiomyopathy
- Trial name
- NCT02149316
- Testing
- RIPC+RIPostC, control
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Chinese Academy of Medical Sciences, Fuwai Hospital
Coronary Artery Disease, Heart Disease
Biorepository: Indiana Health Study
Blood samples and health information (e.g., age at diagnosis, test results) are collected for the purposes of genetic research. The blood samples are assigned a number and stored in a repository for safe keeping until they are…
- Conditions
- Coronary Artery Disease, Heart Disease, Healthy
- Trial name
- IHS (NCT00741416)
- Where
- 14 sites in United States
- Volunteers
- 1,400 people, healthy volunteers welcome
- Sponsor
- Fairbanks Institute
Type 2 Diabetes Mellitus
A 2 Year Trial of Patients With Type 2 Diabetes Focusing on Cardiovascular Diagnostics and Metabolic Control
The purposes of this study are: to investigate the extent of cardiovascular complications in a representative cohort (n=135) of adult patients with type 2 diabetes; to examine if modern non-invasive assessment can replace…
- Trial name
- NCT00133718
- Testing
- Combined lifestyle intervention and optimisation of pharmacological treatment
- Where
- Norway
- Volunteers
- 120 people
- Sponsor
- Asker & Baerum Hospital
Coronary Artery Disease (CAD), Ischemic Heart Disease
ANGIOLITE PMCF Study ( rEPIC04F )
Multicenter, prospective, non-randomized, post-market clinical follow-up (PMCF) study to confirm and support the clinical safety and performance of Angiolite sirolimus eluting stent to meet EU Medical Device regulation (MDR)…
- Trial name
- rEPIC04F (NCT05292014)
- Testing
- ANGIOLITE
- Where
- 6 sites in Spain
- Volunteers
- 81 people
- Sponsor
- Fundación EPIC
Coronary Heart Disease
Application of a New X-ray Protective Device in Coronary Interventional Therapy
This is a multi-center, prospective and controlled clinical trial which will enroll 200 coronary arteriography or percutaneous coronary intervention with 2-4 interventional cardiologist.
- Trial name
- NCT05088291
- Where
- China
- Volunteers
- 200 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Coronary Artery Disease
Effects of Conditioning Exercises and Resistance Interval Training on Post CABG Patients.
Coronary artery disease (CAD) is a global health challenge influenced by diabetes, hypertension, and psychosocial stress, with women having a higher prevalence of Coronary microvascular disease.
- Trial name
- NCT06844591
- Testing
- Conditioning Exercises/ Aerobic Interval Training, Resistance Interval Training
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Riphah International University
Ischaemic Heart Disease
Outcomes of Drug Coated Balloon Angioplasty, A UK Real Life Experience From 2009 to 2015
This is a single center, retrospective, observational cohort study to assess the safety and efficacy of drug coated balloon (DCB) angioplasty in all forms of coronary artery disease.
- Trial name
- DCBNORWICH (NCT03603210)
- Testing
- Drug coated balloon angioplasty
- Where
- United Kingdom
- Volunteers
- 1,000 people
- Sponsor
- Norfolk and Norwich University Hospitals NHS Foundation Trust
Coronary Artery Disease
Comparison Between Right and Left Radial Approach in Patients Undergoing Percutaneous Coronary Procedures
Our aim is to compare between right and left radial approach in patients undergoing percutaneous coronary procedures regarding feasibility and complications.
- Trial name
- NCT05626660
- Testing
- Coronary angiography and percutaneous coronary intervention
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Assiut University
Acute Coronary Syndrome
An Intervention to Reduce Prehospital Delay to Treatment in Acute Coronary Syndrome
This study was conducted to test whether a focused education and counseling intervention delivered by a nurse will decrease time of delay in seeking treatment for the signs and symptoms of acute coronary syndrome (i.e., heart…
- Trial name
- PROMOTION (NCT00734760)
- Testing
- education
- Volunteers
- 3,522 people
- Sponsor
- University of California, San Francisco
Atherosclerosis, Coronary, Coronary Stenosis
Evaluation of Effectiveness and Safety of Rotational Atherectomy in Routine Clinical Practice
This study evaluates the effectiveness and safety rotational atherectomy in routine clinical practice.
- Trial name
- IRIS-ROTA (NCT03427996)
- Testing
- Rotational atherectomy
- Where
- 8 sites in South Korea
- Volunteers
- 500 people
- Sponsor
- Seung-Jung Park
Ischemic Heart Disease
Stress Reduction Intervention for Women With Ischemic Heart Disease
This is a single center, randomized controlled trial which will include women with ischemic heart disease to receive either a self-directed stress reduction program delivered through a smart-phone application or activity tracking…
- Trial name
- NCT02893579
- Testing
- Early SR intervention, Delayed SR intervention
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- NYU Langone Health
Coronary Artery Disease
Safety and Efficacy of Rotational Atherectomy (RA) in Coronary Dissection
This study is aimed at examining the safety and efficacy of rotational atherectomy (RA) in nondilatable calcified lesion complicated by coronary dissection during percutaneous coronary intervention (PCI) procedure.
- Trial name
- NCT01701596
- Testing
- Immediate rotational atherectomy (RA), Delayed rotational atherectomy (RA)
- Where
- China
- Volunteers
- 198 people
- Sponsor
- Xijing Hospital
Coronary Artery Disease
Korean Multicenter Randomized Controlled Trial (RCT) of Pidogul for Patients With Coronary Stenting
The aim of the current study is to compare the antiplatelet efficacy and safety of clopidogrel napadisilate and clopidogrel bisulfate in Coronary Artery Disease (CAD) patients after coronary stent implantation.
- Trial name
- NCT01584791
- Testing
- clopidogrel napadisilate + aspirin, clopidogrel bisulfate + aspirin
- Where
- South Korea
- Volunteers
- 148 people
- Sponsor
- Seoul National University Hospital
Coronary Disease, Coronary Artery Disease
SPIRIT II: A Clinical Evaluation of the XIENCE V® Everolimus Eluting Coronary Stent System
Prospective, randomized, active-control, single blind, parallel two-arm multi-center clinical trial comparing XIENCE V® Everolimus Eluting Coronary Stent System to the approved commercially available active control TAXUS™…
- Conditions
- Coronary Disease, Coronary Artery Disease, Coronary Restenosis
- Trial name
- SPIRIT II (NCT00180310)
- Testing
- XIENCE V® Everolimus Eluting Coronary Stent, TAXUS™ EXPRESS2™ Paclitaxel Eluting Coronary Stent
- Where
- 32 sites in Austria, Belgium and 11 more
- Volunteers
- 300 people
- Sponsor
- Abbott Medical Devices
Acute Coronary Syndrome, Chest Pain
Coronary CT Angiography for Improved Assessment of Suspected Acute Coronary Syndrome
Current evaluation of patients suspected of non-ST-elevation acute coronary syndrome is greatly dictated by the results of high-sensitivity troponins.
- Trial name
- COURSE (NCT03129659)
- Testing
- Coronary CT Angiography
- Where
- 2 sites in Netherlands
- Volunteers
- 230 people
- Sponsor
- Erasmus Medical Center
STEMI
CMR Repeatability in STEMI
The investigators propose to conduct a study to measure the reproducibility of CMR parameters that have been used to predict outcome following PPCI: infarct size, left ventricular volumes, myocardial salvage, microvascular…
- Trial name
- NCT01468662
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- University of Bristol
ST Segment Elevation Myocardial Infarction
iFR-guided Revascularization in STEMI
Functional assessment of non-culprit lesions during percutaneous coronary intervention (PCI) in patients with acute coronary syndrome could improve risk stratification and long-term prognosis.
- Trial name
- WAVE (NCT03561389)
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- Azienda Ospedaliera San Camillo Forlanini
Cardiogenic Shock, Bradycardia
Augmented Pacing for Shock in the Cardiac Intensive Care Unit
The goal of this clinical trial is to learn if backup pacing at an increased rate improves hemodynamics in adults with relative bradycardia, a permanent pacemaker, and cardiogenic shock.
- Conditions
- Cardiogenic Shock, Bradycardia, Shock
- Trial name
- NCT06713668
- Testing
- Backup Pacing Rate Change
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Vanderbilt University Medical Center
Constipation, Coronary Heart Disease
Yannianjiuzhuan Method and Reverse Breathing Training to Improve Constipation in Elderly Patients With Coronary Heart Disease
Primary Purpose: The primary purpose of this study is to evaluate the effectiveness of the Yannianjiuzhuan method combined with reverse abdominal breathing in improving symptoms of constipation, anxiety, sleep quality, and…
- Trial name
- NCT06401460
- Testing
- Yannianjiuzhuan method combined with reverse breathing training
- Where
- China
- Volunteers
- 67 people
- Sponsor
- Junfang Miao
Acute Coronary Syndromes
Impact of Non-medicalized ECG Practices Initiated by SAMU in Dispatch Strategies
The performance of an ECG by non-medicalized prehospital teams (firefighters, first responders, paramedic ambulances) is developing across the territory to cope with the increasing demand (SAMU calls) for a service that cannot…
- Trial name
- ECG-PHNM (NCT07144059)
- Testing
- ECG by the SMUR after medical interrogation by the SAMU, ECG performed by a non-medical vector
- Volunteers
- 350 people
- Sponsor
- Centre Hospitalier Sud Francilien
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