Clinical trials: Coronary Artery Bypass Surgery
Diabetes, Coronary Artery Disease
Epicardial Fat and Clinical Outcomes After Coronary Artery Bypass Grafting in Diabetics vs. Non Diabetics
Cardiovascular disease (CVD) is a group of diseases including both the heart and blood vessels, thereby including coronary heart disease (CHD). To date, diabetics have a higher incidence and prevalence of multivessels CHD.
- Trial name
- NCT03360981
- Testing
- Incretins
- Where
- Italy
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Campania Luigi Vanvitelli
Analgesia
Dexmedetomidine for Pain Reduction in CABG
The purpose of this study is to determine whether adjuvant intravenous dexmedetomidine infusion starting after induction of general anesthesia can provide superior pain management (decrease pain scores) and decrease opioid…
- Trial name
- NCT05534230
- Testing
- Dexmedetomidine Injectable Solution, Saline
- Volunteers
- 100 people
- Sponsor
- Wayne State University
Chronic Coronary Syndrome, Coronary Artery Bypass Graft CABG
Antiplatelet Strategy for CCS Patients Undergoing CABG
To evaluate the long-term outcomes of different antiplatelet strategies, including DAPT, aspirin monotherapy, and clopidogrel monotherapy, in CCS patients undergoing CABG.
- Trial name
- CABG_DAPT_SAPT (NCT06881901)
- Volunteers
- 29,898 people
- Sponsor
- Samsung Medical Center
Coronary Artery Bypass
One-lung Ventilation During Internal Thoracic Artery Grafting in Cardiac Surgery
Coronary artery bypass grafting is a current cardiac surgery. Internal thoracic artery is usually taking to restore coronary revascularization, and its dissection can lead to accidental or voluntary pleural effusions.
- Trial name
- VUPPAM (NCT02823054)
- Testing
- EZ-Blocker
- Where
- France
- Volunteers
- 35 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Coronary Artery Bypass Graft Surgery (CABG), Patient Education
Determining the Consistency Between Nurses and Artificial Intelligence (ChatGPT-5) in Delivering Scenario-Based Discharge Education to Coronary Artery Bypass Graft Patients: A Methodological Study
This methodological study aims to determine the level of agreement between nurses and an artificial intelligence system (ChatGPT-4.0) in providing scenario-based discharge education for patients who have undergone coronary artery…
- Trial name
- CABG-AI-EDU (NCT07263724)
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Hasan Kalyoncu University
Obstructive Sleep Apnea, Ischaemic Heart Desease
Impact of Continuous Positive Airway Pressure (CPAP) Therapy on Outcomes in Patients Undergoing Coronary Revascularization
Investigators assume that continuous positive airway pressure (CPAP) therapy can reduce the mortality, stroke rate and secondary coronary surgery in CAD with obstructive sleep apnea (OSA) patients after percutaneous coronary…
- Trial name
- NCT02080156
- Testing
- CPAP
- Where
- China
- Volunteers
- 1,200 people
- Sponsor
- Beijing Anzhen Hospital
Coronary Artery Obstructive Disease
Relationship Between a Combined Index of Diastolic and Systolic Performance and Intraoperative Hemodynamic Changes During Off-pump Coronary Bypass Surgery
As considering the close relationship between systolic dysfunction and diastolic dysfunction, the EAS index e'/(a' x s') including systolic and diastolic function could be expected to predict hemodynamic changes during off-pump…
- Trial name
- NCT02534103
- Where
- South Korea
- Volunteers
- 120 people
- Sponsor
- Yonsei University
Coronary Artery Disease, Surgery--Complications
Cardiopulmonary Exercise Testing as an Outcome Predictor in Coronary Artery Bypass Surgery
This is a prospective cohort study of patients undergoing coronary artery bypass graft surgery. Prior to surgery, participants will undergo submaximal cardiopulmonary exercise testing on a treadmill.
- Trial name
- NCT03376542
- Testing
- Cardiopulmonary Exercise Testing
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- Eduardo Tibirica, MD, PhD
Cardiac Surgery
Dynamic Tests and Parameters to Predict Fluid Responsiveness After OPCAB
Objective: To assess the predictive value of dynamic tests and parameters for evaluation of fluid responsiveness after off-pump coronary artery bypass grafting (OPCAB).
- Trial name
- NCT04482946
- Testing
- Assessment of fluid responsiveness
- Where
- Russia
- Volunteers
- 32 people
- Sponsor
- Northern State Medical University
Acute Kidney Injury
Intraoperative Dexmedetomidine and Coronary Artery Bypass Graft Surgery
This is a prospective randomized clinical trial designed to determine the effect of intraoperative dexmedetomidine administration on renal function after coronary artery bypass graft surgery.
- Trial name
- NCT06378827
- Testing
- Dexmedetomidine
- Where
- Serbia
- Volunteers
- 100 people
- Sponsor
- University of Novi Sad
Stroke Volume Variation
Effect of Wide Pulse Pressure on the Predictability of Stroke Volume Variation for Fluid Responsiveness in Patients Undergoing Off-pump Coronary Artery Bypass Graft
The investigators examined the predictability of stroke volume variation for fluid responsiveness in patients with wide pulse pressure undergoing off-pump coronary artery bypass graft
- Trial name
- NCT01404455
- Testing
- HES 130/0.4 (VoluvenⓇ, Fresenius Kabi, Graz, Austria) 500mL loading
- Where
- South Korea
- Volunteers
- 66 people
- Sponsor
- Severance Hospital
Post Induction Hypotension
Comparing the Hemodynamic Effects of Volume Loading vs Non-loading During Induction of Anesthesia in Fluid Responder Patients With Coronary Artery Disease Undergoing Elective Coronary Artery Bypass Graft Surgery: a Randomized Controlled Study.
All preoperative cardiac medications will be continued till the morning of the surgery, except angiotensin converting enzyme inhibitors.
- Trial name
- NCT05462847
- Testing
- Ringer acetate
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Kasr El Aini Hospital
Saphenectomy, No Touch
Morbidity of Conventional and No-touch Saphenectomy in Coronary Artery Bypass Grafting.
A clinical research project will be carried out that will consist of a non-inferiority study. The objective is to compare the morbidity of two different surgical techniques for the extraction of the internal saphenous vein…
- Conditions
- Saphenectomy, No Touch, Coronary Artery Disease, Cardiovascular Diseases
- Trial name
- TNT (NCT06496321)
- Testing
- Conventional Saphenous vein harvest, No touch Saphenous vein harvest
- Where
- Uruguay
- Volunteers
- 52 people
- Sponsor
- Instituto Nacional de Cirugia Cardiaca, Uruguay
Coronary Artery Occlusive Disease
The Effect of Tranexamic Acid on Postoperative Blood Loss and Coagulation in Patients With Preoperative Anemia Undergoing Off-Pump Coronary Artery Bypass Graft; Double Blind Randomized Control Study
The Effect of Tranexamic Acid on Postoperative Blood loss and Coagulation in Patients with Preoperative Anemia Undergoing Off-Pump Coronary Artery Bypass Graft; double blind randomized control study.
- Trial name
- NCT01067638
- Testing
- Tranexamic Acid
- Where
- South Korea
- Volunteers
- 90 people
- Sponsor
- Yonsei University
Heart Failure
Is Sacubitril-valsartan Superior to Dapagliflozin in Improving Myocardial Function Performance
The aim of this study is to assess whether sacubitril-valsartan is more effective than dapagliflozin in improving function, myocardial performance in patients undergoing CABG operation or not
- Trial name
- NCT06090487
- Testing
- myocardial function after surgery
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Ain Shams University
Hemodynamic Instability, Postoperative Complications
Fluid Responsiveness: SVV vs esSVV in Mechanically Ventilated and Spontaneously Breathing Patients
Postoperative period after off-pump coronary artery bypass grafting (OPCAB) can be a challenging area for emerging methods for less-invasive continuous hemodynamic monitoring.
- Trial name
- NCT04786652
- Testing
- estimated stroke volume variation (esSVV, Nihon Kohden, Japan), Assessment of fluid responsiveness in mechanically ventilated patients after OPCAB, Assessment of fluid responsiveness in spontaneously breathing patients at 18 hrs of the postoperative period
- Where
- Russia
- Volunteers
- 32 people
- Sponsor
- Northern State Medical University
Coronary Artery Disease
On Versus Off Pump Myocardial Revascularization Study
Compare completeness and modality of revascularization, operative and postoperative results and 1 year clinical outcomes in unselected high risk patients referred for primary coronary artery bypass surgery.
- Trial name
- On-Off (NCT01290952)
- Testing
- Off-pump bypass surgery, On-pump bypass surgery
- Where
- 8 sites in Italy, Switzerland
- Volunteers
- 411 people
- Sponsor
- Medtronic Italia
Myocardial Revascularization, Spinal Anesthesia
Spinal Anesthesia Associated With General Anesthesia in Coronary Artery Bypass
CONTEXT: In patients eligible for coronary artery bypass surgery, anesthesia should provide a number of conditions that exceed the limits of cardiovascular stability, myocardial protection and other organs.
- Conditions
- Myocardial Revascularization, Spinal Anesthesia, Postoperative Care, Fentanyl
- Trial name
- NCT02840006
- Testing
- General anesthesia only, General anesthesia and Spinal anesthesia
- Where
- 2 sites in Brazil
- Volunteers
- 60 people
- Sponsor
- Daniel Gioielli de Castilho
Congestive Heart Failure
Feasibility Study of BMAC Enhanced CABG
Patients undergoing CABG will have 60 mL of bone marrow drawn, concentrated in a SmartPRep2 centrifuge and have the concentrated nucleated cells injected into areas of ischemic myocardium
- Trial name
- NCT01074099
- Testing
- BMAC, CABG only
- Where
- 2 sites in United States
- Volunteers
- 5 people
- Sponsor
- Harvest Technologies
Postoperative Atrial Fibrillation, Strains
Predictive Value of Right Atrial Strain in Postoperative Atrial Fibrillation in Patients Undergoing Cardiac Surgery
The incidence of postoperative atrial fibrillation (POAF) after cardiac surgery is around 30%. POAF increases the risk of developing permanent atrial fibrillation and raises the risk of cardiac decompensation, stroke, acute…
- Trial name
- ODFAPO (NCT06054360)
- Where
- France
- Volunteers
- 334 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
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