Clinical trials: Coronary Artery Bypass Surgery
Postoperative Cognitive Dysfunction
Correlation Between Markers of Neuronal Injury and Cognitive Dysfunction After Coronary Artery Bypass Surgery
This study aims to evaluate the possible Correlation Between Serum Levels of Markers of Neuronal Injury and Cognitive Dysfunction after Coronary Artery Bypass Surgery.
- Trial name
- NCT01550159
- Where
- Brazil
- Volunteers
- 88 people
- Sponsor
- Maria José Carvalho Carmona
Coronary Artery Disease, Cardiac Autonomic Neuropathy
IMPACT OF CARDIAC AUTONOMIC NEUROPATHY ON QT AND QTC INTERVAL
This prospective observational cohort study evaluated the effect of cardiac autonomic neuropathy (CAN) on perioperative ventricular repolarization, specifically QT and corrected QT (QTc) intervals, in patients undergoing elective…
- Conditions
- Coronary Artery Disease, Cardiac Autonomic Neuropathy, QT Interval Prolongation
- Trial name
- QT interval (NCT07684768)
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Haseki Training and Research Hospital
Complication of Extracorporeal Circulation, Complication of Coronary Artery Bypass Graft
Combined Use of a Novel Cardioplegic Formula With Myocardial Protection System (MPS)® Versus Cardioplexol ® in Isolated Coronary Artery Bypass Grafting (CABG) Using MiECC;
Combined use of a novel cardioplegic formula with MPS® (Myocardial protection system) versus Cardioplexol ® (colloid solution with Procaine, magnesium and potassium) in isolated CABG (coronary artery bypass grafting) using MiECC…
- Trial name
- MiECC (NCT03612388)
- Testing
- use of a cardioplegic formula in isolated CABG (coronary artery bypass grafting) using MiECC (Minimal extracorporeal circulation
- Where
- Switzerland
- Volunteers
- 211 people
- Sponsor
- University Hospital, Basel, Switzerland
Coronary Artery Bypass Graft Redo, General Anesthetic Drug Adverse Reaction
The Effect of Desflurane on Myocardial Function in Patients Undergoing Coronary Artery Bypass Grafting
This study is to assess the effect of desflurane on myocardial function in patents who underwent coronary artery bypass grafting.
- Trial name
- NCT02213718
- Testing
- Desflurane, propofol, sufentanil
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Huazhong University of Science and Technology
Prevention of Hypotension
Point Of Care Ultrasound For Prediction Of Fluid Responsiveness in Off Pump Coronary Artery Bypass Grafting Surgery
To exclude hypovolemia before starting off pump coronary artery grafting surgeries by an efficient and good predictive test. We will assess the sensitivity and specificity of dynamic IVC-derived parameters (dispensability index)…
- Trial name
- NCT05968040
- Testing
- Inferior vena cava diameter measurement by ultrasonography, difference between peak velocities of carotid artery by ultrasound, cardiac output be transthoracic echocardiography
- Volunteers
- 40 people
- Sponsor
- Ain Shams University
Diabetes, Coronary Artery Disease
United States Coronary Artery Bypass Surgery (CABG) Diabetes Project (USCDP) Pilot Study
Standard care for patients with diabetes having CABG surgery at Providence St. Vincent Medical Center includes strict control of blood sugar (glucose) levels for 3 days after surgery.
- Trial name
- USCDP (NCT00646438)
- Testing
- Strict Glycemic Control for one year post-op CABG
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Providence Heart & Vascular Institute
Coronary Artery Bypass Surgery
TEE Monitoring and the Incidence of Postoperative Acute Kidney Injury in Coronary Artery Bypass Grafting
TEE has a definite effect on the evaluation of cardiac structure and function in perioperative cardiac surgery. However, in CABG, previous studies on TEE mainly focused on whether to change the surgical plan rather than improve…
- Trial name
- NCT05139108
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Qianfoshan Hospital
Coronary Artery Disease
Current Treatment Strategy of Patients With Multivessel Disease or Left Main Coronary Artery Disease Indicated for Coronary Artery Bypass Graft Surgery
According to 2011 ACCF/AHA guideline and 2014 ESC/EACTS guideline, CABG surgery was recommended for three-vessel coronary artery disease and left main coronary artery disease in the patients with stable ischemic heart disease as…
- Trial name
- NCT02410993
- Testing
- CABG surgery
- Where
- South Korea
- Volunteers
- 2,500 people
- Sponsor
- Yonsei University
Coronary Artery Bypass Surgery
Reduction of Ischemia-Reperfusion Mediated Cardiac Injury in Subjects Undergoing Coronary Artery Bypass Graft Surgery
This clinical trial will investigate the safety and effectiveness of IK-1001 (the liquid form of sodium sulfide) when used in Coronary Artery Bypass Graft (CABG) patients to potentially reduce the damage done to the heart during…
- Trial name
- NCT00858936
- Testing
- IK-1001, Normal Saline
- Where
- 8 sites in Australia, Canada
- Volunteers
- 6 people
- Sponsor
- Mallinckrodt
Coronary Artery Disease (CAD)
Epicardial Delivery of XC001 Gene Therapy to Promote Angiogenesis in CAD Patients Undergoing Treatment With CABG
This is a 26-week (with a 26-week extension) multicenter, randomized, double-blind, placebo-controlled Phase 2 study of XC001 versus placebo.
- Trial name
- EXACT-CABG (NCT07118449)
- Testing
- XC001
- Where
- United States
- Volunteers
- 116 people
- Sponsor
- XyloCor Therapeutics, Inc.
Atrial Fibrillation, Post-Op Complication
Prevention of Postoperative Atrial Fibrillation (POAF) Using Intra-Pericardial Amiodarone
The purpose of this study is to evaluate the combination of CardiaMend, with the addition of amiodarone in the prevention of postoperative atrial fibrillation (POAF) in patients undergoing cardiac arterial bypass grafting (CABG)…
- Trial name
- NCT06063538
- Testing
- CardiaMend in Combination with Amiodarone
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- University of Chicago
Coronary Artery Bypass
Extubation Time in Coronary Artery Bypass Surgery
Many preoperative, intraoperative, and postoperative factors affect the postoperative extubation times of patients who are intubated and taken to the intensive care unit after cardiac surgery.
- Trial name
- NCT07587307
- Testing
- Coronary artery bypass surgery
- Where
- Turkey (Türkiye)
- Volunteers
- 81 people
- Sponsor
- Saglik Bilimleri Universitesi
Ischemic Cardiomyopathy, Congestive Heart Failure
CABG Combined Pedicled Omentum Wrapped Autologous Atrial Tissue Patch Cardiomyoplasty for Ischemic Cardiomyopathy
The purpose of this study is in a phase I/II safety and efficacy study to evaluate the clinical effect of coronary artery bypass graft (CABG) combined pedicled omentum wrapped autologous atrial tissue patch cardiomyoplasty for…
- Conditions
- Ischemic Cardiomyopathy, Congestive Heart Failure, Coronary Artery Disease
- Trial name
- NCT00972114
- Testing
- CABG combined cardiomyoplasty, CABG combined pedicled omentum graft, CABG alone
- Where
- 2 sites in China
- Volunteers
- 70 people
- Sponsor
- China National Center for Cardiovascular Diseases
Coronary Artery Disease, Coronary Artery Bypass
Glycemic Control Using Mobile-based Intervention in Patients With Diabetes Undergoing Coronary Artery Bypass to Promote Self-management
The study is a two-arm parallel, randomized clinical trial. The purpose of the study is to evaluate the effectiveness and feasibility of using high-quality medication reminder smartphone application as a tool for secondary…
- Conditions
- Coronary Artery Disease, Coronary Artery Bypass, Diabetes Mellitus
- Trial name
- GUIDEME (NCT04192409)
- Testing
- Smartphone Application
- Where
- China
- Volunteers
- 1,038 people
- Sponsor
- China National Center for Cardiovascular Diseases
Coronary Artery Bypass Graft Surgery
The Effect of Reflexology After Coronary Artery Bypass Graft Surgery
Coronary artery bypass graft (CABG) surgery is a treatment method that increases survival rate in the treatment of coronary artery disease (CAD).
- Trial name
- NCT04473287
- Testing
- reflexology practice
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Saglik Bilimleri Universitesi
Coronary Artery Disease
Effect of Ultra-Low Tidal Volume on Mechanical Power During Heart Bypass Surgery
The goal of this clinical trial is to evaluate whether ultra-low tidal volume (ULTV) ventilation during cardiopulmonary bypass (CPB) can reduce mechanical power (MP) and improve postoperative respiratory outcomes in adult…
- Trial name
- NCT07073885
- Testing
- Ultra-Low Tidal Volume Ventilation, Apnea Group
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Konya City Hospital
Intubation Complication
Evaluation of Hemodynamic Response to Laryngoscopy and Endotracheal Intubation Using Conventional Laryngoscope Versus C-MAC Video Laryngoscope in Patients Undergoing Elective Coronary Artery Bypass Grafting (CABG) Surgery
This study is being done to compare hemodynamic response upon endotracheal intubation using either conventional laryngoscopy with Macintosh blade versus C-Mac video laryngoscope in patients undergoing elective coronary artery…
- Trial name
- NCT04433884
- Testing
- Endotracheal intubation using a laryngoscope
- Where
- Pakistan
- Volunteers
- 86 people
- Sponsor
- Aga Khan University
Myocardial Infarction, Unstable Angina
Improving Cardiac Rehabilitation Participation in Women and Men
The purpose of this study is to determine the effect of a pre-discharge written personal endorsement to the patient by the patient's attending cardiologist or cardiac surgeon (MD endorsement) to take part in the Cardiac…
- Conditions
- Myocardial Infarction, Unstable Angina, Coronary Disease
- Trial name
- NCT00336830
- Testing
- MD-endorsed Cardiac Rehabilitation referral, Standard Cardiac Rehabilitation referral
- Where
- Canada
- Volunteers
- 1,035 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Coagulation Changes During Coronary Artery Bypass Grafting
Coagulation Profiles in Conventional and Minimal Invasive Extracorporeal Circulation
The aim of this study is to compare the effects of conventional and minimally invasive extracorporeal circulation (MiECC) techniques, which are routinely used in open-heart surgery, on coagulation parameters.
- Trial name
- NCT07844031
- Testing
- Conventional extracorporeal circulation, Minimally invasive extracorporeal circulation
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Minimal Invasive Cardiac Surgery, Mitral Valve Surgery
Serratus Anterior Plane Block for Minimal Invasive Cardiac Surgery
Analgesia in cardiac surgery is historically based on large doses of intravenous opioids. However, this practice is rapidly changing due to "Enhanced Recovery After Surgery (ERAS)" protocols with proven benefits on morbidity and…
- Conditions
- Minimal Invasive Cardiac Surgery, Mitral Valve Surgery, Aortic Valve Replacement, Minimal Invasive Direct Coronary Artery Bypass
- Trial name
- NCT05107453
- Testing
- Levobupivacaine
- Where
- Belgium
- Volunteers
- 80 people
- Sponsor
- Algemeen Ziekenhuis Maria Middelares