Clinical trials: Coronary Artery Bypass Surgery
Elective Coronary Artery Bypass Graft Surgery
Colchicine in Coronary Artery Bypass Graft (CABG)
There is evidence that inflammatory processes may play a key role during surgical myocardial reperfusion. The hypothesis of this study is that colchicine, an anti-inflammatory agent, may lead to reduction in periprocedural…
- Trial name
- NCT02122484
- Testing
- Colchicine
- Where
- Greece
- Volunteers
- 60 people
- Sponsor
- G.Gennimatas General Hospital
Hypoxia
Efficacy and Safety of Using Noninvasive Ventilation Associated With Recruitment Maneuver in Cardiac Surgery.
Cardiac surgery can evolve with complications in the postoperative period, atelectasis and hypoxemia are the major pulmonary dysfunctions.
- Trial name
- NCT02913391
- Testing
- recruitment group (RG), control group (CG)
- Where
- Brazil
- Volunteers
- 34 people
- Sponsor
- Mieko Cláudia Miura
Coronary Artery Bypass Graft Surgery
Effects of ACBT on Pulmonary Function After CABG During Phase 1 Cardiac Rehabilitation
This study is designed to determine the effects of Active cycle of breathing technique (ACBT) on cardiopulmonary parameters of post CABG patients.
- Trial name
- NCT04307316
- Testing
- ACBT group, Conventional Physical therapy
- Where
- Pakistan
- Volunteers
- 40 people
- Sponsor
- Riphah International University
Acute Coronary Syndrome
Early Aggressive Versus Initially Conservative Therapy in Elderly Patients With Non-ST-Elevation Acute Coronary Syndrome
A randomized study comparing an early aggressive with an initially conservative strategy in patients >74 y.o. with non-ST-elevation acute coronary syndrome.
- Trial name
- NCT00510185
- Testing
- systematic coronary intervention, coronary intervention only for cases refractory to medical therapy
- Where
- Italy
- Volunteers
- 313 people
- Sponsor
- Niguarda Hospital
Cardiac Surgery, Aorta No-touch
Hemodynamic Changes During Displacement of the Heart in the Aorta No-touch Off-pump Coronary Artery Bypass Surgery
Introduction: Aorta no-touch off-pump coronary artery bypass surgery (OPCAB) has been the recommended technique for treatment of patients with high-risk of neurological damage or stroke.
- Trial name
- NCT03517189
- Testing
- Aorta no-touch
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- Federal University of São Paulo
Heart Disease, Cardiovascular Disease
Best Bypass Surgery (BBS) Trial
There is evidence linking cardiopulmonary bypass to negative side effects when used for coronary artery bypass grafting. Coronary artery bypass grafting can be performed without the use of cardiopulmonary bypass.
- Trial name
- NCT00120991
- Testing
- Coronary artery bypass grafting
- Where
- Denmark
- Volunteers
- 341 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Coronary Artery Disease
Propofol or Midazolam for Sedation and Early Extubation Following Coronary Artery Bypass Graft Surgery
Propofol and midazolam are used frequently as sedating agents among patients who undergo coronary artery bypass graft surgery but no study in Pakistan has been done to compare their effectiveness aiming early extubation.
- Trial name
- NCT05290324
- Testing
- Midazolam
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Chaudhry Pervaiz Elahi Institute of Cardiology
Coronary Artery Disease
Fractional Flow Reserve Versus Angiography for Multivessel Evaluation (FAME) 3 Extended
Coronary artery disease, or narrowing of the blood vessels that provide blood to the heart, is the most common cause of death in the United States and can be treated with either coronary bypass surgery or coronary stent…
- Trial name
- NCT07308860
- Testing
- FFR-guided PCI, CABG
- Where
- United States
- Volunteers
- 1,500 people
- Sponsor
- Stanford University
Coronary Artery Disease, Stable Coronary Artery Disease
Cardiovascular Events Related to Treated Coronary Arteries in Stable Multivessel CAD
This retrospective cohort study evaluates cardiovascular events directly related to treated coronary arteries in patients with stable multivessel coronary artery disease.
- Conditions
- Coronary Artery Disease, Stable Coronary Artery Disease, Multivessel Coronary Artery Disease, Myocardial Ischemia
- Trial name
- NCT07362108
- Testing
- Coronary Artery Bypass Grafting, Percutaneous Coronary Intervention, Optimized Medical Therapy
- Volunteers
- 1,695 people
- Sponsor
- Instituto do Coracao
Coronary Artery Disease, Sleep Quality
Effect of Eye Mask Use on Sleep Quality and Delirium After CABG Surgery
Coronary artery bypass graft (CABG) surgery is an effective treatment for coronary artery disease; however, sleep disturbances and delirium are common during the postoperative period and may adversely affect recovery.
- Conditions
- Coronary Artery Disease, Sleep Quality, Postoperative Delirium (POD)
- Trial name
- EYE-CABG (NCT07768020)
- Testing
- Eye Mask
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Munzur University
Postoperative Cognitive Dysfunction, Coronary Artery Disease
Short-Term and Long-Term Cognitive Outcomes in Adults After Cardiac Surgery
Adults with coronary artery disease (250 patients) undergoing cardiac surgery participated in the study. The aim is to investigate short-term and long-term cognitive outcomes and the patterns of organization of functional brain…
- Trial name
- NCT05172362
- Where
- Russia
- Volunteers
- 250 people
- Sponsor
- Research Institute for Complex Problems of Cardiovascular Diseases, Russia
Coronary Artery Disease
Hypertonic Solution in Off Pump Coronary Artery Bypass Graft Surgery
This is a comparison between Hypertonic versus isotonic solution in a double blind randomized trial for off pump Coronary Artery Bypass Graft (CABG) surgery targeting the left marginal branch.
- Trial name
- NCT01463917
- Testing
- Hypertonic solution, Isotonic
- Where
- Brazil
- Volunteers
- 20 people
- Sponsor
- Hospital Pitangueiras
Coronary Artery Bypass Surgery, Coronary Heart Disease
An Efficacy and Safety Study for Nesiritide in Heart Failure Patients With Reduced Kidney Function Undergoing Coronary Artery Bypass Graft Surgery Requiring Cardiopulmonary Bypass (CPB Pump or Heart Lung Machine)
The purpose of this study is to assess whether nesiritide compared to placebo when given with standard of care therapies, helps preserve kidney function in heart failure (HF) patients undergoing heart bypass graft surgery that…
- Conditions
- Coronary Artery Bypass Surgery, Coronary Heart Disease, Coronary Artery Bypass Grafting, Cardiopulmonary Bypass
- Trial name
- NCT00530361
- Testing
- Nesiritide
- Sponsor
- Scios, Inc.
Limb Edema, Surgical Site Infections
Prevention of Edema After Coronary Artery Bypass Graft by Customized Pressure-guided Elastic Bandages
The study aimed to assess the efficacy of customized pressure-guided elastic bandages (CPG-EB) in preventing postoperative edema and complications in Coronary Artery Bypass Graft (CABG) patients.
- Conditions
- Limb Edema, Surgical Site Infections, Leg Swelling, Compression Bandages
- Trial name
- PEACCE (NCT06603961)
- Testing
- CPG-EB group
- Where
- 2 sites in Thailand
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Siriraj Hospital
Heart Failure Patients, Cardiac Ischemia
Safety and Efficacy of Cardiac Shockwave Therapy in Patients Undergoing Coronary Artery Bypass Grafting
This randomised, controlled clinical trial aims to evaluate the safety and efficacy of Cardiac Shockwave Therapy (CAST-HF) in patients with ischaemic heart failure requiring surgical revascularization.
- Trial name
- CAST-HF (NCT03859466)
- Testing
- Shockwave Therapy
- Where
- Austria
- Volunteers
- 63 people
- Sponsor
- Medical University Innsbruck
Coronary Artery Bypass Graft
Physical Activity, Functional Fitness and Quality of Life After Coronary Artery Bypass Grafting
The main purposes of this study are: (1) to investigate the difference of the physical fitness, and quality of life (QOL) among different physical activity levels in post-coronary artery bypass graft (CABG) patients; (2) to…
- Trial name
- NCT01591642
- Volunteers
- 315 people
- Sponsor
- Far Eastern Memorial Hospital
Postoperative Cognitive Dysfunction, Cognitive Impairment
Exploration of Neuroimaging and Biochemical Prognostic Indicators for POCD
Postoperative cognitive dysfunction (POCD) may lead to serious consequences. But the underlying mechanisms are still unclear. Blood Oxygen Level Dependent (BOLD) fMRI and biochemical indicators will be used to explore the…
- Trial name
- NCT02164669
- Where
- China
- Volunteers
- 20 people
- Sponsor
- wangqiang
Coronary Stenosis, Coronary Artery Disease
Long-term Follow-up of a Randomized Comparison of Percutaneous Coronary Intervention Versus Coronary Artery Bypass Surgery
This is a long-term follow-up of a completed clinical trial which compared percutaneous coronary intervention (PCI) using sirolimus-eluting stents and coronary artery bypass grafting (CABG) in patients with unprotected left main…
- Trial name
- NCT05963620
- Testing
- percutaneous coronary intervention vs bypass graft surgery
- Where
- 4 sites in Germany
- Volunteers
- 201 people
- Sponsor
- Heart Center Leipzig - University Hospital
Cardiovascular Disease
Phase II Study To Evaluate The Safety and Efficacy of Hemoglobin Raffimer in Patients Undergoing First Time CABG Surgery
To evaluate the efficacy of Hemolink™ in combination with Intraoperative Autologous Donation (IAD) versus control (IAD alone) in facilitating avoidance of allogeneic RBC transfusion during and following primary CABG surgery
- Trial name
- NCT00038454
- Testing
- Hemolink (hemoglobin raffimer IV solution)
- Where
- 28 sites in United States, Canada and 1 more
- Volunteers
- 180 people
- Sponsor
- Hemosol
Coronary Artery Disease
Quantitative Flow Ratio on Radial Artery Graft Outcome After Coronary Artery Bypass Grafting
In coronary artery bypass grafting (CABG), the use of radial artery (RA) is recommended by the guidelines only to significantly stenosed vessel, due to its high vulnerability to competitive flow.
- Trial name
- ASRAB-QUARGO (NCT05556590)
- Where
- China
- Volunteers
- 135 people
- Sponsor
- Ruijin Hospital
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