Clinical trials: Coronary Artery Bypass Surgery
Post-operative Pain Management
Are Superficial Parasternal Intercostal Plane (SPIP) Blocks With Bupivacaine and With or Without Transversus Abdominis Plane Block (TAP) Helpful for Post-operative Pain After Coronary Artery Bypass Grafting?
The purpose of this study is to determine whether superficial parasternal intercostal plane (SPIP) block alone or with transverses abdominis plane (TAP) block can improve post-operative pain in patients undergoing cardiothoracic…
- Trial name
- NCT05090735
- Testing
- SPIP and TAP Block, SPIP Block
- Volunteers
- 100 people
- Sponsor
- Wayne State University
Coronary Artery Disease
The Effect of Video Education on Pain, Anxiety and Knowledge Levels of Coronary Bypass Graft Surgery Patients
The aim of this research to examine the effectiveness of video-education on pain, anxiety, and knowledge levels on adult patients undergoing coronary artery bypass graft surgery.
- Trial name
- NCT06174090
- Testing
- Coronary bypass graft surgery video education
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people
- Sponsor
- Baskent University
Coronary Artery Disease
Perioperative Depression and Postoperative Arrhythmia in Elective Coronary Bypass Graft Surgery
Postoperative arrhythmias (heart irregularities) are one of the most common complications after cardiac surgery and are associated with increased morbidity and mortality.
- Trial name
- NCT00622024
- Where
- Canada
- Volunteers
- 120 people
- Sponsor
- University Health Network, Toronto
OPCABG
Study on the Myocardial Protective Effect of Upper Limb Ischemic Preconditioning in Patients Undergoing Off-pump Coronary Artery Bypass Grafting
The purpose of the study was to verify the myocardial protective effect of RIPC in patients undergoing OPCABG.
- Trial name
- NCT03340181
- Testing
- RIPC
- Where
- China
- Volunteers
- 66 people
- Sponsor
- Shanghai Zhongshan Hospital
Coronary Artery Disease, Coronary Artery Bypass Graft (CABG)
The Effect of Ultra-Fast-Track Cardiac Anesthesia in Coronary Artery Bypass Grafting Surgery
This randomized controlled trial aims to evaluate the impact of Ultra-Fast-Track (UFT) anesthesia on postoperative recovery in patients undergoing elective coronary artery bypass grafting (CABG).
- Trial name
- NCT07207421
- Testing
- Ultra-Fast-Track Anesthesia, Standart care anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Adiyaman University Research Hospital
Systemic Inflammatory Response Syndrome (SIRS), Leukocyte Disorders
Effects of Cardiopulmonary Bypass (CPB)-Leukocyte Filtration on Interleukins Serum Levels and Pulmonary Function
To test the hypothesis that leukocyte filtering during cardiopulmonary bypass (CPB) might reduce the inflammatory response and protect the lungs against the acute injury
- Conditions
- Systemic Inflammatory Response Syndrome (SIRS), Leukocyte Disorders, Complications Due to Coronary Artery Bypass Graft
- Trial name
- PulmFunction (NCT01469676)
- Testing
- Filtering group LG-6, Pall Biomedical Products
- Volunteers
- 22 people
- Sponsor
- University of Sao Paulo
Myocardial Reperfusion Injury, Hypoxia
Effects of Hypoxic-hyperoxic Preconditioning in Cardio-surgical Patients
Coronary artery bypass grafting (CABG) with cardiopulmonary bypass is a common surgical therapy for patients suffering from coronary artery diseases.
- Conditions
- Myocardial Reperfusion Injury, Hypoxia, Hyperoxia, Coronary Artery Disease
- Trial name
- NCT05354648
- Testing
- Hypoxic-hyperoxic preconditioning
- Volunteers
- 120 people
- Sponsor
- Alexander Averyanov
Prehabilitation, Cardiac Surgery
Feasibility of Physical Prehabilitation for High-Risk Patients Undergoing Cardiac Surgery Via Sternotomy
Rationale Cardiac surgery via median sternotomy carries an elevated risk of postoperative complications and delayed functional recovery.
- Conditions
- Prehabilitation, Cardiac Surgery, Risk Assesment, Aortic Valve
- Trial name
- PREPA-STER (NCT07893184)
- Testing
- Physical Prehabilitation Intervention
- Where
- Netherlands
- Volunteers
- 24 people
- Sponsor
- Maastricht University Medical Center
Ischaemic Heart Disease, Contrast-induced Nephropathy
Trial to Assess Whether Computed Tomography Cardiac Angiography Can Improve Invasive Coronary Angiography in Bypass Surgery Patients
A large number of patients with symptomatic ischaemic heart disease undergo coronary artery bypass grafting (CABG) to alleviate their symptoms and improve prognosis.
- Trial name
- BYPASS-CTCA (NCT07022626)
- Testing
- CTCA
- Where
- 2 sites in United Kingdom
- Volunteers
- 688 people
- Sponsor
- Barts & The London NHS Trust
Postoperative Atelectasis
GO2 PEEP Study: Bidirectional Oxygenation Valve in Postoperative Atelectasis
This study compares a novel breathing device, called the GO2 Mouthpiece, to the standard breathing tool called the incentive spirometer, thus improving respiratory dynamics of the postoperative patient.
- Trial name
- NCT04253834
- Testing
- Incentive spirometer, GO2 Mouthpiece
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Emory University
Multi Vessel Coronary Artery Disease
Xeltis Coronary Artery Bypass Graft (XABG) First in Human (FIH)
A prospective, single arm, non-randomized FIH feasibility study to evaluate the preliminary safety and performance of the XABG technology in patients with multi-vessel atherosclerotic coronary artery disease, scheduled by the…
- Trial name
- XABG FIH (NCT04545112)
- Testing
- CABG
- Where
- 4 sites in Belgium, Lithuania and 1 more
- Volunteers
- 20 people
- Sponsor
- Xeltis
Postoperative Acute Kidney Injury After Off-pump Coronary Artery Bypass Graft
Effect of N-acetylcysteine on Prevention of Acute Kidney Injury in High Risk Patients Undergoing Off-pump Coronary Artery Bypass Graft
N-acetylcysteine may prevent acute kidney injury in high risk patients undergoing off-pump coronary artery bypass graft.
- Trial name
- NCT01394419
- Testing
- N-acetylcysteine, Saline
- Where
- South Korea
- Volunteers
- 115 people
- Sponsor
- Yonsei University
Coronary Artery Bypass Graft (CABG)
Saudi CABG Audit and Registry
The Saudi CABG Audit and Registry (SCAR) is a prospective, multicenter national clinical quality registry designed to systematically collect perioperative and long-term outcome data for all patients undergoing coronary artery…
- Trial name
- SCAR (NCT07316777)
- Testing
- Prospective Clinical Data Collection
- Volunteers
- 3,000 people
- Sponsor
- King Faisal Specialist Hospital & Research Center
Brain Ischemia, Postoperative Confusion
Impact of Remote Ischemic Preconditioning Preceding Coronary Artery Bypass Grafting on Inducing nEuroprotection
Coronary artery disease (CAD) is the leading cause of death worldwide. Patients with severe CAD are often treated with coronary artery bypass grafting (CABG).
- Trial name
- RIPCAGE (NCT02177981)
- Testing
- Remote ischemic preconditioning, Control
- Where
- Croatia
- Volunteers
- 70 people
- Sponsor
- University of Zagreb
Coronary Artery Disease, Bypass Complication
Early Silent Graft Failure in Off-pump Coronary Artery Bypass Grafting: A Computed Tomography Analysis
Aortocoronary bypass surgery is one of the most common operations in the western world. The goal of the surgeon is to perform a complete revascularization of the coronary arteries with the best, available bypass material.
- Conditions
- Coronary Artery Disease, Bypass Complication, Graft Failure
- Trial name
- NCT03657199
- Testing
- Cardiac computed tomography
- Volunteers
- 192 people
- Sponsor
- Triemli Hospital
Vitamin D Deficiency, Cardiomyopathies
Can Vitamin D Reduce Heart Muscle Damage After Bypass Surgery?
Background and study aim: Heart diseases are among the most common causes of death worldwide. A large proportion of deaths are caused by heart attacks (myocardial infarction), where blood flow to the heart is reduced resulting in…
- Conditions
- Vitamin D Deficiency, Cardiomyopathies, Apoptosis, Inflammation
- Trial name
- NCT04323852
- Testing
- Vitamin D
- Where
- Iran
- Volunteers
- 70 people
- Sponsor
- Shahid Beheshti University of Medical Sciences
Chronic Total Occlusion
CABG Versus PCI in Patients With Isolated LAD Chronic Total Occlusion
The aim of this study is to compare coronary artery bypass grafting (CABG) and percutaneous coronary intervention (PCI) in the treatment of isolated chronic total occlusion (CTO) of the left anterior descending (LAD) artery in…
- Trial name
- RITUAL (NCT07373678)
- Testing
- Coronary Artery Bypass Grafting, Percutaneous Coronary Intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 302 people
- Sponsor
- Mersin Medicalpark Hastanesi
Coronary Artery Bypass Grafting (CABG) Surgery
Individualized Orem-Based Nursing Intervention After Coronary Artery Bypass Grafting
This randomized controlled trial will evaluate the effectiveness of an individualized self-care and nursing intervention program based on Orem's Self-Care Theory among patients following coronary artery bypass grafting (CABG).
- Trial name
- CABG-OREM (NCT07839598)
- Testing
- Individualized Nursing Intervention Program Based on Orem's Self-Care Theory, Usual postoperative care
- Where
- Jordan
- Volunteers
- 440 people
- Sponsor
- Jerash Private University
Cardiovascular Disease, Ischemic Heart Disease
The Metformin in Coronary Artery Bypass Graft (CABG) (MetCAB) Trial
Rationale: In patients with a myocardial infarction, occlusion of a coronary artery induces myocardial ischemia and cell death. If untreated, the area of myocardium exposed to this interruption in blood supply, will largely…
- Trial name
- MetCAB (NCT01438723)
- Testing
- Metformin
- Where
- Netherlands
- Volunteers
- 100 people
- Sponsor
- Radboud University Medical Center
Systemic Inflammatory Response Syndrome, Coronary Artery Bypass Grafting
Immunomodulation of EA-230 Following On-pump Coronary Artery Bypass Grafting (CABG)
EA-230 is a newly developed synthetic compound with anti-inflammatory properties, it is a linear tetrapeptide derived from the human chorionic gonadotropin hormone (hCG).
- Trial name
- EASI (NCT03145220)
- Testing
- EA-230
- Where
- Netherlands
- Volunteers
- 180 people
- Sponsor
- Radboud University Medical Center
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