Clinical trials: Coronary Artery Bypass Surgery
Left Ventricular Ejection Fraction, Myocardial Revascularization
Revascularization in Heart Failure Trial - REHEAT 2
REHEAT 2 study is designed as a prospective, randomised trial comparing two strategies of myocardial revascularisation (PCI vs CABG) in patients with ischemic cardiomyopathy and low left ventricular ejection fraction.Patients…
- Conditions
- Left Ventricular Ejection Fraction, Myocardial Revascularization, Ischemic Heart Disease
- Trial name
- NCT00388245
- Testing
- Percutaneous Coronary Intervention, Coronary Artery Bypass Grafting
- Where
- 4 sites in Poland
- Volunteers
- 150 people
- Sponsor
- Ministry of Science and Higher Education, Poland
Coronary Artery Disease
Dexmedetomidine's Cardiac and Cognitive Influence on Patients Undergoing Off-pump Coronary Artery Bypass Graft Surgery
The investigators hypothesized that dexmedetomidine as an anesthetic adjunct can be used in the setting of off-pump coronary bypass procedure and can provide benefits to cardiac function and cognitive performance on the ground of…
- Trial name
- NCT01704092
- Testing
- Dexmedetomidine
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Huazhong University of Science and Technology
Coronary Artery Disease
Programme to Optimise Risk Factors in Patients Waiting for Coronary Artery Bypass Surgery
The time spent waiting for heart surgery can be extremely stressful. This programme aims to address this by providing a home-based, nurse-led support and education programme.
- Trial name
- NCT00124371
- Testing
- a nurse led home-based education and support programme
- Where
- United Kingdom
- Volunteers
- 200 people
- Sponsor
- Royal Brompton & Harefield NHS Foundation Trust
Spine Erector, Cardiac Surgery
Comparison Erect Spine in Cardiac Surgery
Open cardiac surgeries are characterized by the increased use of opioids and longer extubation times, being post-sternotomy pain one of the causes of greater patient discomfort, plexus blockages have been used more frequently…
- Conditions
- Spine Erector, Cardiac Surgery, Acute Pain, Chronic Pain
- Trial name
- COESPINE (NCT04313959)
- Testing
- Ropivacaine 0.2% Injectable Solution, Ropivacaine 0.2% + Dexamethasone
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- Instituto do Coracao
POAF, Atrial Fibrillation
CardiaMend and Amiodarone for the Prevention of POAF
The principal purpose of this investigator-initiated trial is to study the use of the CardiaMend device soaked in the anti-arrhythmic drug amiodarone, and how it may decrease the development of atrial fibrillation in patients…
- Trial name
- NCT05641883
- Testing
- CardiaMend with antiarrhythmic
- Volunteers
- 30 people
- Sponsor
- Saint Alphonsus Regional Medical Center
Complications Due to Coronary Artery Bypass Graft
MACCE After Endoscopic Vein Harvest for CABG
Most patients undergoing coronary artery bypass grafting (CABG) will require long saphenous vein (LSV) harvesting from the leg. This has been reported to be associated with a significant morbidity (leg swelling, pain, infection…
- Trial name
- MAQEH (NCT02471456)
- Testing
- Quality of Life Questionnaire, MACCE review
- Where
- United Kingdom
- Volunteers
- 100 people
- Sponsor
- The Royal Wolverhampton Hospitals NHS Trust
Coronary Artery Disease
Prognostic Nutritional Index for Predicting Outcomes Following Coronary Artery Bypass Grafting (CABG) Surgery
Coronary artery bypass grafting (CABG) is a major cardiac surgery associated with risks of serious perioperative complications and mortality.
- Trial name
- NCT07356219
- Testing
- Prognostic Nutritional Index (PNI), Neutrophil-to-Lymphocyte Ratio (NLR), Body Mass Index (BMI)
- Where
- Egypt
- Volunteers
- 117 people
- Sponsor
- Benha University
CABG
Effects of Early Mobility Protocols in Cardiac ICU
In this study the investigator aim to find the effects of early mobility on different physical activity protocols in post CABG patients.
- Trial name
- NCT06029556
- Testing
- Mobility out of Bed, Ergometry in Bed
- Where
- Pakistan
- Volunteers
- 70 people
- Sponsor
- Riphah International University
Coronary Artery Disease
Cost-effectiveness of EGDT Using FloTrac/EV1000
Coronary artery bypass graft (CABG) with cardiopulmonary bypass (CPB) is a high-risk surgery with significant morbidity that results in a prolonged stay in the intensive care unit (ICU) at an increased cost.
- Trial name
- NCT05826795
- Testing
- Early goal-directed therapy (EGDT)
- Where
- 2 sites in Thailand
- Volunteers
- 60 people
- Sponsor
- Khon Kaen University
Coronary Artery Bypass Surgery
Nitrite Mediated Cardioprotection During Coronary Artery Bypass Surgery
The purpose of this study is to determine whether sodium nitrite administration 24 hours prior to or during coronary artery bypass surgery protects the heart better from lack of blood flow which occurs as part of this type of…
- Trial name
- NCT01098409
- Testing
- sodium nitrite, 0.9% sodium chloride
- Where
- United Kingdom
- Volunteers
- 50 people
- Sponsor
- University Hospital Birmingham NHS Foundation Trust
Anemia, Coronary Disease
PBM as Strategy to CABG Anemic Patients Bypass Graft (CABG)
Anemia poses risks during coronary artery bypass grafting (CABG), increasing complications and mortality rates. Blood transfusions in cardiac surgery have negative outcomes, prompting the use of erythropoietin in Patient Blood…
- Conditions
- Anemia, Coronary Disease, Coronary Artery Disease, Coronary Stenosis
- Trial name
- NCT06542393
- Testing
- Erythropoietin, blood transfusion
- Where
- Brazil
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo
Pleural Effusions Post Coronary Artery Bypass Graft
Necessity of Using Pleural Drainage Tubes After IMA Harvesting During Cardiac Surgery
This prospective randomized controlled trial will examine the efficacy of reducing the number of chest tubes used in the postoperative cardiac surgery patient.
- Trial name
- NCT02147821
- Testing
- No Pleural Chest Tube
- Where
- Canada
- Volunteers
- 162 people
- Sponsor
- University of Calgary
Heart Failure, Revascularization
Percutaneous Coronary RevascularizatiOn VERsus Coronary-Artery Bypass Grafting for Multivessel Disease in Patients With Left Ventricular Dysfunction (PROVERB)
A short description, 5000 characters Ischemic cardiomyopathy related to coronary artery disease is currently the leading cause of heart failure.
- Trial name
- PROVERB (NCT05532631)
- Testing
- Percutaneous coronary intervention, Coronary artery bypass grafting
- Where
- France
- Volunteers
- 1,040 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Ischaemic Heart Diseases
Loop Isolation-based Uploading Pre-conditioning
Myocardial protection is of crucial importance for surgical coronary revascularization in patients with ischaemic heart diseases.
- Trial name
- NCT03766529
- Testing
- loop isolation-based uploading preconditioning (LiuPhD)
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Nanjing Medical University
Melatonin, Anxiety
Melatonin on Anxiety and Sleep Quality in Adults Undergoing Coronary Artery Bypass Graft Surgery
The objective of this study is to evaluate the effect of melatonin on post operative sleeping quality, anxiety, and post-operative opioid requirements in adults post coronary artery bypass graft (CABG) surgery.
- Conditions
- Melatonin, Anxiety, Sleep Quality, Coronary Artery Bypass Graft
- Trial name
- NCT06237556
- Testing
- Melatonin 5 MG
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Ain Shams University
Coronary Artery Bypass, Cognitive Dysfunction
The Influence of Cognitive Decline on Quality of Life After Coronary Bypass
During the last decades improvements in operative techniques and perioperative care have led to a steady decline in mortality after cardiac surgery.
- Trial name
- NCT03774342
- Testing
- Coronary Artery Bypass Grafting
- Where
- Netherlands
- Volunteers
- 140 people
- Sponsor
- University Medical Center Groningen
Myocardial Stunning
Ranolazine a Potential New Therapeutic Application
Despite surgical and medical innovation have reduced mortality rates in cardiac surgery, the disease severity and operative procedural complexity have increased and morbidity rate is still high.
- Trial name
- NCT02687269
- Testing
- Ranolazine
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Coronary Artery Disease
Expression of Angiogenic Factors in Myocardial Tissue
The purpose of this study is to evaluate whether angiogenesis is decreased in diabetic patients with coronary artery disease compared to non-diabetics with coronary artery disease.
- Trial name
- NCT01414621
- Testing
- atrial tissue sample
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Virginia
Acute Kidney Injury (AKI)
A Study to Evaluate RMC-035 in Subjects Undergoing Cardiac Surgery
The purpose of the clinical study is to assess safety, tolerability and pharmacokinetics of RMC-035 for the prevention and treatment of acute kidney injury (AKI) in patients undergoing cardiac surgery.
- Trial name
- NCT04829916
- Testing
- RMC-035
- Where
- Germany
- Volunteers
- 13 people
- Sponsor
- Guard Therapeutics AB
Clinical Outcomes, Cardiac Surgery
Predictors Of Outcome After Coronary Artery Bypass Graft Surgery Using Cardiopulmonary Bypass
In cardiac operations, high values of blood lactate have been associated with bad outcomes if detected both during CPB and at the arrival in the intensive care unit (ICU) in adult patients.
- Conditions
- Clinical Outcomes, Cardiac Surgery, Cardio-pulmonary Bypass
- Trial name
- NCT07034716
- Testing
- CORONARY BYPASS SURGERY USING CARDIOPULMONARY BYPASS, cardiac surgical patients who will undergo isolated elective cardiopulmonary bypass
- Volunteers
- 60 people
- Sponsor
- Alexandria University
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.