Clinical trials: Coronary Artery Bypass Surgery
Coronary Artery Disease, Aortic Valve Stenosis
Personalized Activity Intervention in Rehabilitation After Cardiac Operations (the PACO Trial)
The PACO trial is a randomized clinical trial conducted in Heart Centers of Kuopio and Turku university hospitals. The coronary artery disease, aortic valve stenosis and mitral valve insufficiency patients preparing for elective…
- Conditions
- Coronary Artery Disease, Aortic Valve Stenosis, Mitral Valve Insufficiency
- Trial name
- PACO (NCT03470246)
- Testing
- PACO intervention for CABG patients, PACO intervention for AVR patients, PACO intervention for MVR patients
- Where
- Finland
- Volunteers
- 540 people
- Sponsor
- Kuopio University Hospital
Pleural Effusion, Coronary Artery Bypass
Pleural Effusion Following Cardiac Surgery: Prevalence, Risk Factors and Clinical Features
Pleural effusion is a common complication of cardiac surgery. The aim of this study was to determine the prevalence, characteristics and determinants of clinically significant pleural effusions, defined as those requiring…
- Trial name
- NCT00665015
- Where
- Canada
- Volunteers
- 2,892 people
- Sponsor
- Laval University
Coronary Artery Disease With Need for Bypass Surgery, Myocardial Ischemia, Angina Pectoris
Bypass Surgery and CD133 Marrow Cell Injection for Treatment of Ischemic Heart Failure
Cell transplantation for treatment of heart failure is a novel field of translational research that offers the perspective of developing curative approaches by regenerating or "rejuvenating" lost and/or diseased myocardium and…
- Conditions
- Coronary Artery Disease With Need for Bypass Surgery, Myocardial Ischemia, Angina Pectoris, Congestive Heart Failure, Previous Myocardial Infarction
- Trial name
- Cardio133 (NCT00462774)
- Testing
- Intramyocardial injection of autologous CD133+ marrow cells
- Where
- Germany
- Volunteers
- 60 people
- Sponsor
- German Heart Institute
Coronary Artery Bypass Surgery, Self Care
Tele-Nursing Counseling in Coronary Artery Bypass Graft Surgery
It was planned as randomized controlled experimental study to examine the effect of post discharge telenursing counseling on symptom control and self-care in patients who undergoing coronary artery bypass graft surgery.
- Conditions
- Coronary Artery Bypass Surgery, Self Care, Telenursing
- Trial name
- NCT07664306
- Testing
- THE EFFECT OF TELENURSING COUNSELING ON SYMPTOM CONTROL AND SELF-CARE ABILITY IN PATIENTS UNDERGOING CORONARY ARTERY BYPASS GRAFT SURGERY.
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Fenerbahce University
Chronic Obstructive Pulmonary Disease, Cardiac Surgery
Chronic Obstructive Pulmonary Disease as a Predictor of Mortality in Cardiac Surgery
To estimate prevalence of chronic obstructive pulmonary disease (COPD) in cardiac surgery population and establish links between COPD status, as assessed through pulmonary functional tests, and 2-year mortality
- Trial name
- NCT02392065
- Where
- Russia
- Volunteers
- 1,100 people
- Sponsor
- Meshalkin Research Institute of Pathology of Circulation
Coronary Artery Bypass, Anesthesia
Sustainable Anesthesia in Myocardial Revascularization Surgery.
Introduction: Greenhouse gases threaten the health and safety of humanity. The Declaration of Helsinki seeks to protect human health and emphasizes the urgency of implementing sustainable strategies.
- Conditions
- Coronary Artery Bypass, Anesthesia, Sustainability
- Trial name
- NCT07508865
- Testing
- Optimized recovery, Standard Anesthetic Practice
- Where
- Chile
- Volunteers
- 116 people
- Sponsor
- Universidad de La Frontera
Myocardial Ischemia, Acute Coronary Syndrome
EARLY ACS: Early Glycoprotein IIb/IIIa Inhibition in Patients With Non-ST-segment Elevation Acute Coronary Syndrome (Study P03684AM2)(COMPLETED)
The purpose of this study is to see if early INTEGRILIN® (eptifibatide) therapy in patients with non-ST-segment elevation acute coronary syndrome (ACS) reduces the occurence of death, heart attack and urgent cardiac intervention…
- Trial name
- NCT00089895
- Testing
- Eptifibatide (Integrilin)
- Volunteers
- 9,406 people
- Sponsor
- Organon and Co
Bypass, Cardiopulmonary
Menthol Massage for Post-Bypass Pain & Anxiety
This randomized controlled trial aims to evaluate the effectiveness of mentholated ointment massage in reducing pain and anxiety levels in patients who have undergone coronary bypass surgery, volunteered to participate in the…
- Trial name
- Menthol Care (NCT07508371)
- Testing
- Menthol Massage, Massage
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Istanbul Medipol University Hospital
Coronary Artery Disease
MOTIV Study- Effect of Antidepressive Treatment by Escitalopram in Patients Undergoing Coronary Artery Bypass Grafting
The purpose of this study is to determine the effect of an antidepressive medication (Escitalopram), started preoperatively and given during 6 months, on 6-month and 1 year post-operative morbidity and mortality after coronary…
- Trial name
- NCT00243477
- Testing
- Escitalopram
- Where
- France
- Volunteers
- 368 people
- Sponsor
- Hopital Jean Minjoz
Atrial Fibrillation
Human Amniotic Membrane to Decrease Post Operative Atrial Fibrillation
This study will evaluate the application of hAM at the time of cardiac surgery to decrease inflammation and the subsequent substrate to reduce incidence of post-operative atrial fibrillation.
- Trial name
- NCT04130061
- Testing
- Human Amniotic Membrane
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- University of Utah
Diastolic Dysfunction, Coronary Artery Disease
Study of the Effect of Inhaled Anesthetics on Diastolic Heart Function Using a Doppler-derived Efficiency Index
The purpose of this study is to determine the effect of inhaled anesthetic drugs upon diastolic heart function (heart suction and filling performance) in patients who are undergoing coronary bypass surgery.
- Conditions
- Diastolic Dysfunction, Coronary Artery Disease, General Anesthesia
- Trial name
- NCT00907439
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Washington University School of Medicine
Coronary Artery Bypass Graft
Prospective Data Analysis of a Quality Improvement Initiative in High Risk Cardiac Surgery Patients
This project is designed to assess the impact of implementing a hemodynamic optimization protocol, utilizing flow guided parameters that is provided by technology from Edwards Lifesciences, for patients undergoing high risk…
- Trial name
- NCT04458701
- Testing
- Hemodynamic monitoring
- Where
- United States
- Volunteers
- 195 people
- Sponsor
- Loma Linda University
CAD - Coronary Artery Disease, CABG
A Randomized Controlled Trial: Fuzheng Yangxin Formula for ERAS After CABG
This study aims to evaluate the efficacy and safety of Fuzheng Yangxin Formula (FZYXF) in the treatment of qi-yin deficiency syndrome after coronary artery bypass grafting (CABG), formulate an integrated Chinese and Western…
- Conditions
- CAD - Coronary Artery Disease, CABG, ERAS, Medicine, Chinese Traditional
- Trial name
- FZYXF-RCT-CABG (NCT07781436)
- Testing
- FZYX
- Where
- China
- Volunteers
- 230 people
- Sponsor
- Peking University Third Hospital
Coronary Artery Disease
Programme to Optimise Risk Factors in Patients Waiting for Coronary Artery Bypass Surgery
The time spent waiting for heart surgery can be extremely stressful. This programme aims to address this by providing a home-based, nurse-led support and education programme.
- Trial name
- NCT00124371
- Testing
- a nurse led home-based education and support programme
- Where
- United Kingdom
- Volunteers
- 200 people
- Sponsor
- Royal Brompton & Harefield NHS Foundation Trust
Coronary Artery Disease
Long-term Exercise in Older Cardiac Patients
Using a randomized clinical trial with 3 groups, the investigators will conduct a head-to-head evaluation of two different theoretically-based interventions, SystemCHANGE and CHANGE+, as compared to Usual Care to improve the…
- Trial name
- NCT02323919
- Testing
- SystemCHANGE, CHANGE+, Usual Care
- Volunteers
- 379 people
- Sponsor
- Case Western Reserve University
Metabolism Disorder
Conventional Fasting Versus Lipid/Carbohydrate Infusion for Coronary Bypass Patients
Comparative study between conventional fasting versus overnight infusion of lipid or carbohydrate on free fatty acids and insulin in obese patients undergoing elective first time on-pump coronary artery bypass grafting.
- Trial name
- NCT03033667
- Testing
- G group, group L, Group C
- Volunteers
- 63 people
- Sponsor
- Cairo University
CABG
Effects of E-care Protocol in Patients With Coronary Artery Bypass Graft
Coronary artery disease (CAD) is a heart disease caused by the buildup of plaque inside the coronary arteries that restricts blood flow to the heart which leads to heart attack.
- Trial name
- CABG (NCT07574411)
- Testing
- IMT Threshold device
- Volunteers
- 42 people
- Sponsor
- Riphah International University
Acute Kidney Injury
Effect of Sodium Bicarbonate on Prevention of Acute Kidney Injury in High Risk Patients Undergoing Off-pump Coronary Artery Bypass (OPCAB)
In this single-site, randomized, controlled and double-blind clinical trial, the investigators evaluate the effect of sodium bicarbonate on prevention of acute kidney injury in high risk patients undergoing off pump coronary…
- Trial name
- NCT01840241
- Testing
- sodium bicarbonate, normal saline
- Where
- South Korea
- Volunteers
- 162 people
- Sponsor
- Yonsei University
Cardiac Surgery, Coronary Artery Bypass Graft
Micro- and Macro-Circulation in Cardiac Surgery Patients
The hypothesis under the study is that there could be a link between a dysfunction in peripheral microcirculation, sublingual microcirculation or cardiovascular control and the development of post cardiac surgery major…
- Conditions
- Cardiac Surgery, Coronary Artery Bypass Graft, Surgical Aortic Valve Replacement
- Trial name
- MiMaC (NCT05706545)
- Testing
- Acquisition of cardiovascular signals and microcirculation sidestream darkfield images
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- IRCCS Policlinico S. Donato
Cardiovascular Diseases, Coronary Artery Disease
Senescence in Myocardial Infarction
The investigators of this study have found that after a heart attack, some heart cells rapidly age (become senescent) and release proteins that make the heart disease worse.
- Conditions
- Cardiovascular Diseases, Coronary Artery Disease, Aging, Atherosclerosis
- Trial name
- SMI (NCT07693712)
- Where
- United Kingdom
- Volunteers
- 22 people
- Sponsor
- South Tees Hospitals NHS Foundation Trust
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