Clinical trials: Coronary Artery Occlusion
Coronary Artery Disease
Comparison of Two Methods of Strain by Perioperative Transesophageal Echo in CABG : An Observational Study
There is an increasing need for diagnostic modalities able to objectively quantify myocardial function. Quantification of regional myocardial function with ultrasound is challenging on its own.
- Trial name
- Strain (NCT02692131)
- Where
- India
- Volunteers
- 50 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Coronary Artery Disease
Physical Exercise and Coronary Artery Plaque Composition
The purpose of this study is to examine the effect of two different physical exercise protocols on changes in coronary artery plaque composition and development of in-stent restenosis in patients treated with percutaneous…
- Trial name
- NCT01228201
- Testing
- Moderate continuous training, Aerobic interval training
- Where
- Norway
- Volunteers
- 40 people
- Sponsor
- Trondheim University Hospital
Coronary Artery Disease
Home-Based Versus Center-Based Cardiac Rehabilitation After CABG Surgery
This randomized controlled trial was designed to compare the efficacy of a 12-week home-based telerehabilitation (HBTCR) program against traditional center-based cardiac rehabilitation (CBCR) and usual care in patients who have…
- Trial name
- NCT07243444
- Testing
- Structured Exercise Program, Standard Health Education
- Where
- China
- Volunteers
- 110 people
- Sponsor
- The First Hospital of Hebei Medical University
Stable Angina, Unstable Angina, Silent Coronary Ischemia, Coronary Artery Disease
ISAR-DAPT (A Comparative Evaluation of Efficacy and Safety in the 3-Months DAPT Group vs. the 6-Months DAPT Group of Patients Treated With the Coroflex ISAR Stent; A Prospective, Multicenter, Randomized, Open-Label Clinical Trial)
This clinical trial studies patients treated with the Coroflex ISAR Stent for coronary artery disease in order for the objective of verifying the non-inferiority of results that among patients who were administered DAPT for 3…
- Trial name
- NCT02609698
- Testing
- Coroflex ISAR, 3 months DAPT, 6 months DAPT
- Where
- South Korea
- Volunteers
- 906 people
- Sponsor
- Ajou University School of Medicine
Atherosclerosis, Cardiovascular Diseases
Coffee Consumption and Coronary Artery Calcium Score
Coffee is one of the dietary factors associated with cardiovascular disease (CVD) but its role in the cardiovascular system is not yet clear.
- Trial name
- NCT03139071
- Where
- Brazil
- Volunteers
- 4,426 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Coronary Artery Disease
Adhesiveness of Coronary Drug-Eluting Stents to the Delivery Balloon-Catheter: A Randomized Comparison
This study will evaluate the 3 drug-eluting stents presently marketed for intervention in the coronary artery with respect to the complications that may occur in case it becomes necessary to retract the stent during the…
- Trial name
- NCT00279006
- Testing
- Percutaneous coronary intervention
- Volunteers
- 150 people
- Sponsor
- Foundation for Cardiovascular Research, Zurich
Coronary Arterial Disease (CAD), Acute Coronary Syndrome (ACS) Undergoing Percutaneous Coronary Intervention (PCI)
Artificial Intelligence Based Timing, Infarct Size and Outcomes in Acute Coronary Occlusion Myocardial Infarction
The present study is practice-driven and merely observational and prospective. In clinical routine, patients who suffer from suspected ACS and do not show ST elevation in the ECG, different timing proposals in the guidelines and…
- Trial name
- ANOMI (NCT06910436)
- Testing
- Coronary Angiogram
- Where
- Italy
- Volunteers
- 1,500 people
- Sponsor
- Azienda Ospedaliera di Bolzano
Coronary Artery Disease
Safety and Efficacy Study of PB127 Ultrasound Contrast Agent in Patients With Suspected Coronary Artery Disease
This trial is to compare PB127 echocardiography to other heart imaging studies.
- Trial name
- NCT00595244
- Testing
- PB127 for injectable suspension
- Where
- 15 sites in United States
- Volunteers
- 456 people
- Sponsor
- Point Biomedical
Hypertension, Coronary Arteriosclerosis
Inflammation and Coronary Artery Disease: Role of AT1-Receptor Antagonism
Effects of AT1 receptor antagonist telmisartan on the primary endpoint inflammatory parameters in patients with coronary artery disease (CAD). Secondary endpoints are alterations in clinical course and blood pressure
- Trial name
- NCT00274144
- Testing
- telmisartan 40 mg
- Where
- Germany
- Volunteers
- 42 people
- Sponsor
- Boehringer Ingelheim
Coronary Artery Disease
Efficacy Study of Hydroxychloroquine to Treat High-risk Coronary Artery Disease.
The purpose of this study is to evaluate whether treated with hydroxychloroquine could improve therapeutic effect for patients with high-risk coronary artery disease.
- Trial name
- CHANGAN (NCT02874287)
- Testing
- Hydroxychloroquine Sulfate Tablets
- Where
- China
- Volunteers
- 35 people
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Atherosclerotic Heart Disease, Coronary Heart Disease
Safety and Efficacy of the Percutaneous Intervention Performed With Devices of a Single-brand
The freedom of choice in medicine is based on the physician's ability to treat their patients with the best available therapy. The armamentarium for percutaneous intervention is frequently determined on the basis of subjective…
- Trial name
- Tsunami (NCT01632501)
- Testing
- Coronary stent - Tsunami
- Volunteers
- 84 people
- Sponsor
- Hospital Sao Lucas da PUCRS
Coronary Artery Disease
Plaque Stability and Metabolomics in Coronary Heart Disease
At present, the investigators don't know the relationship between plaque stability and the metabonomics changes. In the present study, investigators will evaluate the plaque stability by intravascular unltrasound in stable…
- Trial name
- NCT05270330
- Testing
- This is an observational study, we don't have any interventions.
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Shaanxi Provincial People's Hospital
Coronary Artery Disease
Triglyceride-Glucose Indices and Left Ventricular Speckle Tracking in Predicting Coronary Artery Disease Severity
Our study specifically will address the value of modified triglyceride glucose indices versus left ventricular speckle tracking in prediction of severity of coronary artery disease assessed by Gensini score.
- Trial name
- NCT07063628
- Testing
- TyG-derived index., Left Ventricular Speckle Tracking
- Where
- Egypt
- Volunteers
- 508 people
- Sponsor
- Damanhour University
Lipid-Rich Atherosclerosis of Coronary Artery
REASSURE-NIRS Registry
RESSURE-NIRS registry is designed to investigate clinical and pathophysiological characteristics of NIRS-derived lipid-rich plaque in patients with coronary artery disease.
- Trial name
- REASSURENIRS (NCT04864171)
- Testing
- near-infrared spectroscopy
- Where
- 2 sites in Japan
- Volunteers
- 2,000 people
- Sponsor
- National Cerebral and Cardiovascular Center, Japan
Coronary Artery Disease
Aminoterminal Propeptide of Type III Procollagen and Severity of Coronary Artery Disease in Patients Without Myocardial Infarction
Background: Myocardial fibrosis is a major component in cardiac remodeling in patients with myocardial infarction or hibernation.
- Trial name
- NCT00172432
- Sponsor
- National Taiwan University Hospital
Coronary Artery Disease, Chest Pain
CT-FIRST: Cardiac Computed Tomography Versus Stress Imaging For Initial Risk STratification
In patients with chest pain or shortness of breath who are referred for stress imaging tests (either stress echocardiography or stress nuclear testing), the investigators seek to compare impact of using cardiac CT scans of the…
- Conditions
- Coronary Artery Disease, Chest Pain, Coronary Atherosclerosis, Stress Testing
- Trial name
- CT-FIRST (NCT01061398)
- Testing
- Cardiac CT Angiography, Stress Imaging Test (Stress Myocardial Perfusion Study or Stress Echocardiogram)
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- Walter Reed Army Medical Center
Coronary Artery Disease
Multislice Computed Tomography Assessment of PCSK9 Inhibition on Coronary Perfusion
The MARKOV study is an investigator-sponsored single arm, prospective study to assess the effect of evolocumab on the improvement in coronary flow (FFRCT) after 18 and 36 months of treatment in patients with coronary…
- Trial name
- MARKOV (NCT03851263)
- Testing
- Evolocumab
- Sponsor
- ECRI bv
Coronary Artery Disease (CAD)
Coroflex ISAR 2000 Extended Registry (ISAR2000 Extended)
Postmarket surveillance in terms of the safety and efficacy of Sirolimus-eluting Coroflex ISAR Stent for the treatment of "real world" patients with de-novo and restenotic lesions after stand-alone angioplasty in coronary…
- Trial name
- NCT02905214
- Testing
- stenting with the Coroflex ISAR sirolimus-eluting stent
- Where
- 3 sites in Germany, Malaysia and 1 more
- Volunteers
- 4,369 people
- Sponsor
- B. Braun Melsungen AG
Coronary Artery Disease (CAD), Ischemic Heart Disease
Essential Pro PMCF Study ( rEPIC04E )
Multicenter, prospective, non-randomized, post-market clinical follow-up (PMCF) study to confirm and support the clinical safety and performance of Essential Pro to meet EU Medical Device regulation (MDR) requirements in all the…
- Trial name
- rEPIC04E (NCT05292092)
- Testing
- Essential pro
- Where
- 7 sites in Spain
- Volunteers
- 161 people
- Sponsor
- Fundación EPIC
Coronary Artery Disease
Efficacy and Safety Study of Binodenoson in Assessing Cardiac Ischemia
Binodenoson (an experimental drug) and adenosine (an FDA-approved drug that is currently used by doctors) are used to increase blood flow to the heart just like when a person exercises on a treadmill.
- Trial name
- VISION-302 (NCT00944294)
- Testing
- binodenoson, adenosine
- Volunteers
- 419 people
- Sponsor
- Pfizer
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