Clinical trials: Coronary Atherosclerosis
Valvular Disease, Valvular Heart Disease
Epidemiology and Long-term Outcome of Patients With VHD
Valvular heart diseases are significant problem in Polish population. Coexistence of coronary artery disease in patients with VHD increases the risk of death and affects further therapeutic strategy.
- Conditions
- Valvular Disease, Valvular Heart Disease, Aortic Valve Stenosis, Mitral Insufficiency and Aortic Stenosis
- Trial name
- BIA-WAD (NCT04527367)
- Testing
- Innovative medical technologies in invasive cardiology and cardiac surgery
- Where
- Poland
- Volunteers
- 2,500 people
- Sponsor
- Medical University of Bialystok
Coronary Artery Disease Obliterative, Chronic Total Occlusion (CTO)
A Prospective, Non-Randomized Pivotal Clinical Investigation to Demonstrate the Safety and Performance of the TrueCross Single-Use Microcatheter
The trial is a pivotal clinical investigation, which is a prospective, non-randomized pivotal clinical investigation to demonstrate the safety and performance of the TrueCross Single-use Microcatheter.
- Trial name
- NCT06030271
- Testing
- Microcatheter
- Where
- 7 sites in Georgia, Greece and 1 more
- Volunteers
- 60 people
- Sponsor
- Insight Lifetech Co., Ltd.
Cardiovascular Diseases, Heart Diseases
Atherosclerosis and Omega-3 Fatty Acids in Alaskan Natives
To determine whether there were differences in the prevalence and extent of atherosclerotic lesions in the coronaries and aortas between Alaskan natives and non-natives, and whether the extent of the lesions was related to…
- Conditions
- Cardiovascular Diseases, Heart Diseases, Atherosclerosis, Coronary Arteriosclerosis
- Trial name
- NCT00005236
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Coronary Artery Bypass
Neurocognitive Outcome After Coronary Artery Bypass Surgery Using Minimal Versus Conventional Extracorporeal Circulation
The aim of this study is to assess the effect of minimal (MECC) versus conventional (CECC) extracorporeal circulation on neurocognitive function after elective coronary bypass grafting (CABG) as well as whether this can be…
- Trial name
- NCT01213511
- Testing
- Coronary artery bypass grafting with the use of minimal extracorporeal circulation, Coronary artery bypass grafting under conventional extracorporeal circulation
- Where
- Greece
- Volunteers
- 64 people
- Sponsor
- AHEPA University Hospital
Acute Coronary Syndrome
IDE-ALERTS Continued Access Study
This Continued Access IDE Study includes a subset of former ALERTS trial (NCT00781118) patients and provides performance data for a refined Guardian implantable medical device (AMSG3-E) with a new battery designed to extend…
- Trial name
- ALERTS-CAS (NCT04316481)
- Testing
- AngelMed Guardian System
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Angel Medical Systems
Patients With Type 2 DM Who Underwent Coronary Angiography Due to Coronary Artery Disease and Presence of Microvascular Complications in Same Patients
Correlation Between Micro Vascular Complications and Severity of Coronary Artery Disease in Type 2 DM
Diabetes is a major cause of morbidity and mortality worldwide and it contributes substantially to healthcare costs. Type 2 Diabetes mellitus is the most common type of diabetes accounting for approximately (90%) of all cases.
- Trial name
- NCT04975828
- Testing
- albumin creatinine ratio -EGFR-fundus examination- coronary angiography.
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Sohag University
Coronary Heart Disease
Determination of Coronary Flow Reserve by Dynamic Myocardial Perfusion Scintigraphy
Because of its availability, non-invasiveness, and high diagnostic performance, myocardial perfusion tomoscintigraphy has become a standard tool for the detection, characterization and monitoring of coronary artery disease.
- Trial name
- ERCAD (NCT03326167)
- Testing
- Myocardial Perfusion Imaging by Single Photon Emission Computed Tomography (MPI SPECT)
- Where
- France
- Volunteers
- 15 people
- Sponsor
- Hospices Civils de Lyon
Coronary Artery Disease
Cobra II Study: Use of the Cobra™ Cobalt Super Alloy Coronary Stent System in the Treatment of Coronary Artery Disease
To demonstrate the safety and efficacy of the Cobra Cobalt Super Alloy Balloon-Expandable Coronary Stent System for the treatment of de novo and restenotic (previously unstented) lesions in native coronary arteries in subjects…
- Trial name
- NCT00744107
- Testing
- PCI with the Cobra™ Cobalt Super Alloy Coronary Stent System
- Where
- 7 sites in Germany, Israel and 2 more
- Volunteers
- 258 people
- Sponsor
- Medlogics Device Corporation
Coronary Artery Disease
The PLATINUM Clinical Trial to Assess the PROMUS Element Stent System for Treatment of De Novo Coronary Artery Lesions in Small Vessels
The purpose of this study is to evaluate the safety and effectiveness of the PROMUS Element™ Everolimus-Eluting Coronary Stent System for the treatment of patients with up to 2 de novo atherosclerotic coronary artery lesions.
- Trial name
- PLATINUM SV (NCT01498692)
- Testing
- PROMUS Element Coronary Stent System
- Where
- 23 sites in United States, Australia and 4 more
- Volunteers
- 94 people
- Sponsor
- Boston Scientific Corporation
Coronary Artery Disease(CAD), de Novo Coronary Lesions
The Safety and Efficacy of New-Generation BRS vs. DCB for De Novo Large Coronary Artery Lesions: A Prospective RCT
This study plans to enroll 150 patients who are candidates for "intervention without implantation" therapy and they will be randomly assigned in a 1:1 ratio to either the new-generation Firesorb scaffold group (BRS group, N=75)…
- Trial name
- NCT07162792
- Testing
- bioresorbable scaffold, drug-coated balloon
- Volunteers
- 150 people
- Sponsor
- Xuzhou Third People's Hospital
Rheumatoid Arthritis
The Effects of Cardiac Rehabilitation on Cardiovascular Disease Risk in Rheumatoid Arthritis Patients
Rheumatoid arthritis (RA) is a chronic inflammatory disease that affects approximately 1% of all Canadians. RA is associated with a higher rate of disease and death as well as a decreased life expectancy.
- Trial name
- NCT01534871
- Testing
- Exercise
- Where
- Canada
- Volunteers
- 14 people
- Sponsor
- Nova Scotia Health Authority
Coronary Artery Disease, Coronary Stenosis
Contrast Enhancement on Coronary Computed Tomographic Angiography
Computed tomographic angiography (CTA) is an important prognostic tool with regard to the detection of coronary artery stenoses.
- Trial name
- EICAR (NCT02462044)
- Testing
- 240 mg Iodine, 300 mg Iodine, 370 mg Iodine
- Where
- Netherlands
- Volunteers
- 200 people
- Sponsor
- Maastricht University Medical Center
Coronary Heart Disease
Vascular Healing After BVS-implantation
Evaluation of coronary artery vessel wall healing at different time points in patients undergoing implantion of bioresorbable vascular scaffold by using intravascular imaging.
- Trial name
- NCT03079934
- Testing
- Absorb-BVS
- Where
- Germany
- Volunteers
- 26 people
- Sponsor
- LMU Klinikum
Coronary Disease
The Usefulness of Coronary CT Scan After Everolimus-eluting Bioabsorbable Scaffold Implantation for Coronary Artery Disease
The purpose of this study is to evaluate usefulness of coronary computed tomographic scan for prediction of clinical events after everolimus-eluting bioabsorbable scaffold implantation for coronary artery disease.
- Trial name
- CT BVS (NCT02981134)
- Testing
- Computed tomographic scan
- Where
- South Korea
- Sponsor
- Jung-min Ahn
Coronary Artery Disease
Detection of Coronary Artery Disease Using Analysis of High Frequency QRS: The HyperQ Registry
This will be a registry study that will enroll patients referred for an ECG treadmill test with nuclear myocardial perfusion imaging (MPI).
- Trial name
- HyperQ (NCT01325467)
- Where
- 3 sites in United States
- Volunteers
- 900 people
- Sponsor
- BSP Biological Signal Processing Ltd.
Coronary (Artery); Disease
Trial of MiStent Compared to Xience in Japan
To compare the MT005 (MiStent) with the XIENCE with respect to target lesion failure (TLF) at 12 months in a non-inferiority trial in a "real world" patient population and to confirm that the domestic extrapolation of the…
- Trial name
- DESSOLVEJ (NCT02972671)
- Testing
- MiStent (MT005) Coronary Artery Stent, Xience Coronary Artery Stent
- Where
- 10 sites in Japan
- Volunteers
- 120 people
- Sponsor
- Micell Technologies
Coronary Artery Disease, Angina Pectoris
Comparison of Cypher Select and Taxus Express Coronary Stents
Randomized nine months clinical comparison of implantation of Taxol eluting (Taxus Express) and Sirolimus eluting (Cypher Select) stents in non-selected patients with coronary artery disease.
- Trial name
- SORT-OUTII (NCT00388934)
- Testing
- Drug eluting stent
- Volunteers
- 2,095 people
- Sponsor
- Aarhus University Hospital Skejby
Coronary Artery Disease, Coronary Ischemia
The Association Between Different Monocyte Subsets and Coronary Collateral Development
Collateral growth and coronary angiogenesis are chronic adaptations to myocardial ischemia. Collateralization helps to restore blood flow and as a result salvages myocardium in severely ischemic myocardial regions.
- Trial name
- NCT01356836
- Where
- Turkey (Türkiye)
- Volunteers
- 105 people
- Sponsor
- Yuksek Ihtisas Hospital
Coronary Artery Disease, Atrial Fibrillation (AF)
Medical Large Language Model-Assisted Diagnosis and Treatment in Primary Care Chronic Disease Management
This study aims to explore the feasibility of using medical large language models to assist in chronic disease management. By setting up experimental and control group interventions and having experts blindly evaluate anonymized…
- Conditions
- Coronary Artery Disease, Atrial Fibrillation (AF), Heart Failure, Stroke
- Trial name
- NCT07740044
- Testing
- Medical large language model
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Jiangsu Taizhou People's Hospital
Acute Coronary Syndrome
Evaluation of Ticagrelor Anti Platelet and Pleiotropic Effects in Patients Undergoing Percutaneous Coronary Intervention for an Acute Coronary Syndrome
Ticagrelor is a new P2Y12 ADP receptor antagonist. This drug demonstrated a faster onset of action and a higher potency compared to clopidogrel standard regimen.
- Trial name
- NCT01626534
- Testing
- Clopidogrel, trigagrelor
- Where
- France
- Volunteers
- 125 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
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