Clinical trials: Coronary Bypass
Coronary Artery Bypass, Anesthesia, Conduction
Effect of Transversus Thoracic Muscle Plane Block (TTMP) on Analgesia
In this prospective and controlled study, the investigators investigated the effect of transversus thoracic muscle plane block (TTMP) on analgesia in patients who undergo coronary artery bypass graft (CABG) surgery with median…
- Conditions
- Coronary Artery Bypass, Anesthesia, Conduction, Nerve Block, Pain, Postoperative
- Trial name
- NCT06601530
- Testing
- Transversus Thoracic Muscle Plane Block, Tramadol
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people
- Sponsor
- Istanbul University - Cerrahpasa
Coronary Artery Bypass Surgery
Study of Role of Blood Microvescicles and Exosomes in Patients With Graft Occlusion After Aortocoronary Bypass Surgery
Coronary artery bypass graft (CABG) surgery is still the standard treatment of coronary revascularization for patients with severe coronary artery disease (CAD).
- Trial name
- MVBYPASS (NCT05411445)
- Where
- Italy
- Volunteers
- 300 people
- Sponsor
- Maria Cecilia Hospital
Coronary Artery Disease of Significant Bypass Graft, Metabolic Dysfunction-associated Fatty Liver Disease
Positive Association of US-FLI With the Severity of CAD
As a multisystem disease, metabolic dysfunction-associated fatty liver disease (MAFLD) is closely linked to the onset and progression of coronary heart disease (CHD).
- Conditions
- Coronary Artery Disease of Significant Bypass Graft, Metabolic Dysfunction-associated Fatty Liver Disease, SYNTAX Score, Ultrasonography
- Trial name
- NCT06541132
- Testing
- Observational study without human intervention
- Where
- China
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- Chongqing Medical University
Minimal Invasive Cardiac Surgery, Mitral Valve Surgery
Serratus Anterior Plane Block for Minimal Invasive Cardiac Surgery
Analgesia in cardiac surgery is historically based on large doses of intravenous opioids. However, this practice is rapidly changing due to "Enhanced Recovery After Surgery (ERAS)" protocols with proven benefits on morbidity and…
- Conditions
- Minimal Invasive Cardiac Surgery, Mitral Valve Surgery, Aortic Valve Replacement, Minimal Invasive Direct Coronary Artery Bypass
- Trial name
- NCT05107453
- Testing
- Levobupivacaine
- Where
- Belgium
- Volunteers
- 80 people
- Sponsor
- Algemeen Ziekenhuis Maria Middelares
Coronary Artery Bypass Surgery
To Determine the Effectiveness of Transesophageal Lung Ultrasound Guided Recruitment Maneuver in Cardiac Surgery
This study is to evaluate the effectiveness of Transesophageal Lung ULtrasound (TELUS) guided recruitment maneuver to reduce lung atelelectasis in cardiac surgery.
- Trial name
- TELUS-REM (NCT06513702)
- Testing
- Transesophageal lung ultrasound (TELUS) guided recruitment maneuver, Manual bag lung reinflation
- Volunteers
- 60 people
- Sponsor
- University of Malaya
Fluid Therapy, Coronary Artery Bypass Surgery Patients
Evaluation of Fluid Responsiveness With Recruitment Maneuver After Sternotomy in Coronary Artery Bypass Surgery
Assuming that the basic reliability of dynamic indices will increase with the application of functional hemodynamic tests after sternotomy and protective lung ventilation in patients undergoing elective coronary artery bypass…
- Conditions
- Fluid Therapy, Coronary Artery Bypass Surgery Patients, Lung Recruitment Maneuver
- Trial name
- fluidresponse (NCT06249568)
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Ankara City Hospital Bilkent
Coronary Artery Bypass
VEST Device to Enhance Safein Vein Patency
Purpose - Bypass grafting is the gold standard for severe coronary disease, yet most repeat revascularizations target previously grafted territories.
- Trial name
- NCT06500897
- Testing
- VEST
- Where
- 3 sites in Austria, Italy
- Volunteers
- 385 people
- Sponsor
- Cardiochirurgia E.H.
Coronary Artery Bypass Grafting, Remote Ischemic Conditioning
Safety and Efficacy of Remote Ischemic Conditioning for Patients Taking Off-pump Coronary Artery Bypass Grafting
Remote ischemic conditioning (RIC) is the process of repeated ischemia and reperfusion in the peripheral vessels, which is proved in reducing IRI in vital organs.
- Conditions
- Coronary Artery Bypass Grafting, Remote Ischemic Conditioning, Ischemia-Reperfusion Injury
- Trial name
- IMPROVE (NCT06141525)
- Testing
- Remote ischemic conditioning
- Where
- China
- Volunteers
- 648 people
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Post Operative Pain, Post Operative Anxiety
The Effect of Virtual Reality on Postoperative Pain and Anxiety in Cardiac Surgery.
The objective of this study is to investigate the effect of VR on post-operative pain and anxiety management in cardiac surgery patients undergoing a coronary artery bypass grafting (CABG) procedure.
- Conditions
- Post Operative Pain, Post Operative Anxiety, Heart Surgery, Coronary Artery Bypass Grafting
- Trial name
- VRECOVERY (NCT06001502)
- Testing
- Virtual Reality distraction therapy
- Where
- Netherlands
- Volunteers
- 100 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Coronary Artery Bypass Graft Surgery(CABG)
Effects of Balance Training on Functional Capacity of Patients After Coronary Artery Bypass Grafting Surgery
Background:There are still many gaps in research concerning the effect of balance training on functional capacity of patient after coronary artery bypass graft.
- Trial name
- NCT06490458
- Testing
- Balance Training
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Coronary Artery Bypass
Enhancing Care Study in Patients After CABG
Review the data of patients who underwent coronary artery bypass grafting (CABG) at the National Center for Cardiovascular Disease, Fuwai Hospital from January 2013 to June 2023 including medical history, head CT scan, and…
- Trial name
- OptiCABG (NCT06488352)
- Where
- China
- Volunteers
- 40,000 people
- Sponsor
- Chinese Academy of Medical Sciences, Fuwai Hospital
Diabetes Mellitus, Type 2, Coronary Artery Disease
POST-CABGDM: Empagliflozin in Perioperative CABG
Introduction: Diabetes Mellitus (DM) is a condition known to be associated with coronary artery disease (CAD) and its role as promoter of atherosclerosis is well stablished.
- Conditions
- Diabetes Mellitus, Type 2, Coronary Artery Disease, Coronary Artery Bypass Surgery, Acute Kidney Injury
- Trial name
- POST-CABGDM (NCT04523064)
- Testing
- Empagliflozin 25 MG
- Where
- Brazil
- Volunteers
- 155 people
- Sponsor
- University of Sao Paulo General Hospital
Coronary Artery Bypass Graft Surgery
Long-acting Parasternal Blocks for Analgesia After Cardiac Surgery
This is a randomized, double-blind, controlled clinical trial is to evaluate the duration of efficacy of parasternal blocks with the use of local anesthetic adjuncts for analgesia after coronary artery bypass grafting surgery.
- Trial name
- NCT05191745
- Testing
- Parasternal blocks, Standard of care
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Jewish General Hospital
Coronary Artery Disease, Percutaneous Coronary Intervention
Assessment of Adverse Outcome in Asymptomatic Patients With Prior Coronary Revascularization Who Have a Systematic Stress Testing Strategy Or a Non-testing Strategy During Long-term Follow-up.
Due to the lack of randomized controlled trials, the best follow-up strategy of asymptomatic patients after coronary artery revascularization is controversial.
- Conditions
- Coronary Artery Disease, Percutaneous Coronary Intervention, Coronary Artery Bypass Grafting
- Trial name
- ARCACHON (NCT04566497)
- Testing
- No stress testing, stress testing
- Where
- France
- Volunteers
- 2,664 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Coronary Artery Bypass, Myocardial Ischemia
Glutamate for Metabolic Intervention in Coronary Surgery
The main purpose of this study is to determine whether intravenous glutamate infusion given in association with surgery for unstable coronary artery disease can protect the heart from myocardial injury, postoperative heart…
- Conditions
- Coronary Artery Bypass, Myocardial Ischemia, Myocardial Infarction, Coronary Artery Disease
- Trial name
- GLUTAMICS (NCT00489827)
- Testing
- Intravenous infusion of saline, Intravenous glutamate infusion
- Where
- 3 sites in Sweden
- Volunteers
- 865 people
- Sponsor
- University Hospital, Linkoeping
Mitral Valve Insufficiency, Mitral Valve Annuloplasty
Study on Surgical Treatment Strategies for Moderate Ischemic Mitral Regurgitation
This study aimed to compare the efficacy of isolated coronary artery bypass grafting and coronary artery bypass grafting + mitral valve repair in moderate ischemic mitral regurgitation patients through a cohort and explore the…
- Conditions
- Mitral Valve Insufficiency, Mitral Valve Annuloplasty, Coronary Artery Bypass
- Trial name
- NCT06408779
- Testing
- mitral valve repair
- Where
- China
- Volunteers
- 464 people
- Sponsor
- China National Center for Cardiovascular Diseases
Coronary Artery Bypass, Off-Pump, Iron Deficiencies
Effect of Non-anemic Iron Deficiency on Outcome Following Off-pump Coronary Revascularization
This is a single center retrospective study of patients who underwent off pump coronary artery bypass surgery between 2016.11~2023.05.
- Trial name
- NCT06399627
- Where
- South Korea
- Volunteers
- 433 people
- Sponsor
- Yonsei University
Complication of Coronary Artery Bypass Graft, Atrial Fibrillation
Atrial Fibrillation Prevention in Post Coronary Artery Bypass Graft Surgery With Cryoablation for Ganglionic Plexi
Atrial fibrillation after coronary artery bypass graft is a common complication. The investigators have thought that the mechanism of temporarily postoperative atrial fibrillation is closely related to the autonomic nervous…
- Trial name
- NCT02035163
- Testing
- Two sites cryoablation
- Where
- South Korea
- Sponsor
- Yong Seog Oh
Coronary Artery Bypass Grafting
Tissue Oxygenation During Heart Surgery
The goal of this study is to determine if off-pump CABG surgery is associated with better cerebral tissue oxygenation when compared with on-pump CABG.
- Trial name
- NCT01347827
- Testing
- measurements of brain tissue oxygenation
- Where
- Netherlands
- Volunteers
- 60 people
- Sponsor
- University Medical Center Groningen
Coronary Artery Disease, Coronary Artery Bypass Graft Surgery
The Effect of Listening to Holy Quran Recital on the Incidence of Delirium Post-CABG
This study is planned to check the effect of holy Quran recital on the development of delirium after conronary artery bypass graft surgery (CABG).
- Conditions
- Coronary Artery Disease, Coronary Artery Bypass Graft Surgery, Delirium, Postoperative
- Trial name
- NCT06346990
- Testing
- Holy Quran Recital
- Volunteers
- 264 people
- Sponsor
- Applied Science Private University