Clinical trials: Coronary Bypass
Percutaneous Coronary Intervention, Saphenous Vein
Short and Long-term Results of PCI in no Touch Vein-graft.
Coronary artery disease is one of the biggest health issue worldwide.The treatment, in a large part of the patients, implicates a so called bypass-operation, that consists in to connect new vascular conduits (grafts) beyond the…
- Conditions
- Percutaneous Coronary Intervention, Saphenous Vein, Coronary Artery Bypass
- Trial name
- NCT03999398
- Testing
- Percutaneous coronary intervention (PCI)
- Where
- Sweden
- Volunteers
- 260 people
- Sponsor
- Region Örebro County
Chest Wall Blocks
Serratus Anterior Plan Block (SAP) and Pectoralis (PECSI-II) Blocks on Left Internal Mammarian Artery (LIMA) Blood Flow
To investigate whether the anterior chest wall blocks performed before the surgery have an effect on the LIMA (left internal mammarian artery) blood flow in patients who will undergo coronary artery bypass surgery.
- Trial name
- NCT05907798
- Testing
- LIMA Blood flow
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Yuzuncu Yil University
Coronary Artery Disease
Assessing Vein Graft Properties Between Conventional & No-Touch Harvesting Technique - (PATENT SVG)
The purpose of this study is to compare saphenous veins harvested using the atraumatic pedicled ("no-touch") technique to saphenous veins harvested using the conventional open technique in patients undergoing isolated coronary…
- Trial name
- NCT01488084
- Testing
- Coronary Artery Bypass Graft Surgery, Conventional open SVG harvesting
- Where
- Canada
- Volunteers
- 15 people
- Sponsor
- Sunnybrook Health Sciences Centre
Coronary Artery Bypass Grafting
Complement Activation and Central Nervous System Injury After Coronary Artery Surgery
The impact of the postoperative inflammatory response on the central nervous system after cardiac surgery is uncertain. The goal of this study was to evaluate the role of complement activation on cellular brain injury and…
- Trial name
- NCT00188006
- Testing
- heparin-coated cardiopulmonary bypass
- Sponsor
- University Hospital, Angers
Coronary Artery Bypass Graft (CABG), Chest Tubes
Chest Tube-Delivered Bupivacaine to Decrease Postoperative Pain After Cardiac Surgery
Background: After heart surgery, patients require temporary chest tubes - plastic drains placed inside the chest to prevent fluid building up around the heart and lungs.
- Conditions
- Coronary Artery Bypass Graft (CABG), Chest Tubes, Post Operative Pain Control
- Trial name
- FREEZE-B (NCT07643506)
- Testing
- 0.5% Bupivacaine without epinephrine, 10cc injection of normal saline (0.9%)
- Volunteers
- 60 people
- Sponsor
- University of Calgary
Quantitative Flow Reserve, Minimally Invasive Coronary Surgery
The Impact of Preoperative Quantitative Flow Reserve (QFR) on Early Postoperative Radial Artery Graft Outcomes in Coronary Artery Bypass Grafting
The goal of this observational study is to learn about the long-term effects of Quantitative Flow Reserve (QFR) assessment in patients undergoing Coronary Artery Bypass Grafting (CABG).
- Conditions
- Quantitative Flow Reserve, Minimally Invasive Coronary Surgery, Radial Artery
- Trial name
- QFR-RADIAL (NCT07669987)
- Testing
- Observational
- Where
- China
- Volunteers
- 110 people
- Sponsor
- Peking University Third Hospital
Heart Surgery
Negative Venous Line Pressure in a Miniaturised Cardiopulmonary Bypass Circuit (CPB)
Study to measure the ability of a 'fenestrated' venous line cannula to reduce the negative line pressure seen with kinetic-assist active venous drainage (KAVD) in a standard miniaturised cardiopulmonary bypass circuit and thereby…
- Trial name
- NCT03717649
- Testing
- Conventional 2-stage venous cannula, Conventional 3-stage venous cannula, Fenestrated 3-stage venous cannula
- Volunteers
- 48 people
- Sponsor
- University Hospital Plymouth NHS Trust
Postoperative Delirium (POD)
Perioperative Dezocine Administration and Postoperative Delirium in Elderly Cardiac Surgery Patients
Postoperative delirium (POD) is a common complication in elderly patients undergoing cardiac surgery and is associated with prolonged hospitalization, increased morbidity, and poor recovery.
- Trial name
- NCT07768150
- Testing
- Dezocine, Normal Saline (NS)
- Where
- 2 sites in China
- Volunteers
- 640 people
- Sponsor
- Chinese Academy of Medical Sciences, Fuwai Hospital
Coronary Artery Bypass Graft Triple Vessel
MicroRNA Mediates Volatile Anesthetics Preconditioning Induced Artery Protection
It has been reported that volatile anesthetics preconditioning mediates protection of organ via microRNA. We want to study on the effects of isoflurane preconditioning on expression of microRNA and mRNA in the specimens of…
- Trial name
- NCT02678650
- Testing
- volatile anesthetics(isoflurane), propofol intravenous anesthesia
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Liang Zhang
Coronary Artery Disease, Coronary Artery Bypass Grafting
Total Arterial vs. Mixed Grafting in Left Coronary CABG
This is a prospective, randomized, double-blind controlled trial comparing the clinical efficacy of total arterial grafting (internal thoracic artery and radial artery) versus conventional mixed grafting (internal thoracic artery…
- Conditions
- Coronary Artery Disease, Coronary Artery Bypass Grafting, Arterial Graft, Graft Patency
- Trial name
- NCT07057713
- Testing
- Total Arterial Grafting, Conventional Mixed Grafting
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Second Hospital of Jilin University
Coronary Disease
Comparison of the Risk of Stroke With On- Versus Off-Pump Coronary Artery Bypass Grafting
This study will compare the safety of coronary artery bypass grafting (CABG) with and without the use of heart-lung bypass during surgery (on- versus off-pump surgery).
- Trial name
- NCT00046410
- Where
- United States
- Volunteers
- 340 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Ischemic Heart Disease
Long-term Outcomes and Prognostic Factors in Patient Undergoing CABG or PCI
1. To evaluate the long-term clinical outcomes and prognostic factors in patients with coronary artery disease undergoing coronary artery bypass graft surgery. 2.
- Trial name
- NCT03870815
- Testing
- CABG, PCI
- Where
- South Korea
- Volunteers
- 10,000 people
- Sponsor
- Samsung Medical Center
Patients on Clopidogrel, Platelets Transfusion
Frequency of Platelets Transfusion & Post-Operative Bleeding Risk in Patients on Clopidogrel Undergoing CABG
The goal of this retrospective cohort study Is to Primarily be platelet transfusion frequency and postoperative bleeding risk, analysis using descriptive and inferential statistics in all eligible patients admitted to the cardiac…
- Trial name
- NCT07600060
- Where
- Pakistan
- Volunteers
- 227 people
- Sponsor
- Aga Khan University
Cognitive Dysfunction, Postoperative
Effect of Targeted Fluid Therapy on Postoperative Cognitive Dysfunction.
Postoperative cognitive dysfunction (POCD) describes a decline in cognitive function as measured by pre- and postoperative neuropsychological testing.
- Trial name
- NCT06797713
- Testing
- Esophageal doppler, Conventional method
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- TC Erciyes University
Disorder; Heart, Functional, Postoperative, Cardiac Surgery, Cardiac Insufficiency Following Cardiac Surgery
Statin Therapy In Atrial Refractoriness and Reperfusion Injury
Patients with coronary artery disease are often prescribed drugs called statins because research has shown that, by lowering cholesterol, they reduce the risk of having a heart attack or other complications in the long-term.
- Conditions
- Disorder; Heart, Functional, Postoperative, Cardiac Surgery, Cardiac Insufficiency Following Cardiac Surgery, Atrial Fibrillation, Ischaemia-reperfusion Injury
- Trial name
- STARR (NCT01780740)
- Testing
- Atorvastatin
- Where
- United Kingdom
- Volunteers
- 80 people
- Sponsor
- University of Oxford
Heart Valve Diseases, Systemic Inflammatory Response Syndrome
Corticosteroid Prophylaxis on the Cardiopulmonary Bypass-Induced Systemic Inflammatory Response
To observe the effect of glucocorticoid on the dynamic changes of monocyte subsets in the peripheral blood of valve disease patients undergoing cardiopulmonary bypass perioperatively.
- Trial name
- NCT01296074
- Testing
- Corticosteroid
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Beijing Anzhen Hospital
Mechanical Complication of Coronary Artery Bypass Graft, Respiratory Depression
Effects of Osteopathic Treatment on Pulmonary Function After Coronary Artery Bypass Graft Surgery
The purpose of this study is to determine the short and long term effects of osteopathic treatment on pulmonary function, pain and quality of life in patients after coronary artery bypass graft (CABG) surgery.
- Conditions
- Mechanical Complication of Coronary Artery Bypass Graft, Respiratory Depression, Pain, Quality of Life
- Trial name
- OSTinCARE (NCT01714791)
- Testing
- Usual care, Osteopathic treatment
- Where
- Belgium
- Volunteers
- 112 people
- Sponsor
- Hartcentrum Hasselt
Cardiovascular Diseases, Coronary Artery Disease
The Effect of Continued Mechanical Ventilation on the Occurrence of Myocardial Ischemia
The goal of this study is to examine the influence of mechanical ventilation on the occurrence of myocardial ischemia in patients undergoing endo-CABG.
- Conditions
- Cardiovascular Diseases, Coronary Artery Disease, Myocardial Ischemia, Hypoxia
- Trial name
- VENTMICS-II (NCT05417217)
- Testing
- Discontinued ventilation, Continued ventilation
- Where
- Belgium
- Volunteers
- 165 people
- Sponsor
- Jessa Hospital
Coronary Artery Bypass Graft Surgery (CABG), Pain
Effect of Swedish Hand Massage on Pain in Patients Undergoing CABG Surgery
Coronary Artery Bypass Grafting (CABG) surgery is performed commonly today. Heart surgery performed on more than two million individuals every year leads patients experience severe postoperative pain for causes such as cutting of…
- Conditions
- Coronary Artery Bypass Graft Surgery (CABG), Pain, Pain Management, Nursing
- Trial name
- NCT06688617
- Testing
- Swedish Hand Massage
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Istanbul University - Cerrahpasa
Coronary Artery Disease
Association Between Vitamin D and Perioperative Hemoglobin Levels in Patients Undergoing Off-pump Coronary Artery Bypass Graft Surgery: Role of Hepcidin
Preoperative anemia is present in more than 50% of patients undergoing cardiac surgery, which is associated with increased risk of transfusion, increased length of stay in the intensive care unit, and increased incidence of renal…
- Trial name
- NCT04986033
- Where
- South Korea
- Volunteers
- 135 people
- Sponsor
- Yonsei University
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