Clinical trials: Coronary Bypass
Coronary Artery Disease, Type II Diabetes Mellitus
Innovative Strategies For Risk Reduction Following CABG
Background: Treatment targets for cardiac risk factor reduction are not being met. Therefore, there is a need for new strategies to assist patients in meeting these goals.
- Trial name
- NCT00462436
- Testing
- Consumption of Dietary Portfolio
- Where
- Canada
- Volunteers
- 35 people
- Sponsor
- Unity Health Toronto
Cardiac Complication During Procedure
Prospective Double Blinded Randomized Control Study of the Use of Fibrinogen in High-Risk Cardiac Surgery
The aim of the study is to show that first line treatment with concentrated fibrinogen has superiority over the conventional therapy with fresh frozen plasma (FFP), platelets, and cryoprecipitate in perioperative management of…
- Trial name
- NCT01623531
- Testing
- Fibrinogen
- Where
- Canada
- Volunteers
- 62 people
- Sponsor
- Nova Scotia Health Authority
Coronary Artery Disease
Technology-Enhanced Continuous Nursing System (TECNS) for Post-CABG Recovery
This is a prospective, randomized controlled trial to evaluate the effectiveness of a Technology-Enhanced Continuous Nursing System (TECNS) compared to routine care for patients after coronary artery bypass grafting (CABG).
- Trial name
- NCT07117331
- Testing
- Technology-Enhanced Continuous Nursing System, Routine Postoperative Care
- Where
- China
- Volunteers
- 358 people
- Sponsor
- The First Hospital of Hebei Medical University
Heart Failure
CentriMag Ventricular Assist System in Treating Failure-to-Wean From Cardiopulmonary Bypass
The purpose of the study is to evaluate the safety and effectiveness of the CentriMag ventricular assist system to help patients who have experienced heart failure during surgery and cannot be removed from cardiac bypass.
- Trial name
- NCT00819793
- Testing
- CentriMag Ventricular Assist System
- Where
- 14 sites in United States
- Volunteers
- 32 people
- Sponsor
- Abbott Medical Devices
Percutaneous Coronary Artery Intervention, Coronary Artery Bypass Graft
Effect of Chinese Traditional Medicine for Post Revascularization Treatment of Coronary Artery Disease
The purpose of this study is to built the standard of Chinese Traditional Medicine test for Post percutaneous coronary artery intervention and coronary artery bypass graft，also for acute coronary syndrome，according to the…
- Conditions
- Percutaneous Coronary Artery Intervention, Coronary Artery Bypass Graft, Acute Coronary Syndrome
- Trial name
- NCT00965471
- Testing
- cipher prescription 1, cipher prescription 2
- Volunteers
- 940 people
- Sponsor
- Guangzhou University of Chinese Medicine
Coronary Atherosclerotic Heart Disease
Relationship Between Apelin and New-onset Atrial Fibrillation After Coronary Artery Bypass Grafting
To investigate whether apelin can be used as an indicator to predict postoperative atrial fibrillation in patients with coronary atherosclerotic heart disease, and to provide an objective basis for the clinical selection of a…
- Trial name
- NCT02807532
- Testing
- atrial fibrillation, non-atrial fibrillation
- Volunteers
- 120 people
- Sponsor
- General Hospital of Shenyang Military Region
Coronary Artery Disease
Study of the PAS-Port® Proximal Anastomosis System in Coronary Bypass Surgery
The study has been designed to comparatively evaluate the safety and effectiveness of the PAS-Port Proximal Anastomosis System and conventional suturing techniques for creation of the connection between graft veins and the aorta…
- Trial name
- EPIC (NCT00355563)
- Testing
- PAS-Port Automated Proximal Anastomosis System
- Where
- United States
- Volunteers
- 220 people
- Sponsor
- Cardica, Inc
Heart Defects, Congenital
Effects of Perioperative Nesiritide or Milrinone Infusion on Recovery From Fontan Surgery
The staged surgical pathway to treat children with single ventricle heart defects culminates with the Fontan operation. In this procedure, systemic venous return is rerouted directly to the pulmonary arteries, which serves to…
- Trial name
- NCT00543309
- Testing
- nesiritide, milrinone
- Where
- United States
- Volunteers
- 106 people
- Sponsor
- John M Costello
Coronary Artery Bypass, Off-Pump, Intraoperative Hypotension
Intraoperative Hypotension and Acute Kidney Injury After Off-pump Coronary Artery Bypass Grafting Surgery
Acute renal injury (AKI) is a common complication after cardiac surgery and is associated with worse outcomes. Hypotension is an important risk factor for the development of AKI after noncardiac surgery.
- Conditions
- Coronary Artery Bypass, Off-Pump, Intraoperative Hypotension, Acute Kidney Injury
- Trial name
- NCT03889730
- Where
- China
- Volunteers
- 821 people
- Sponsor
- Peking University First Hospital
Atrial Fibrillation, Ischemic Heart Disease
The New Pharmaceutical Composition Containing Botulinum Toxin to Treat Atrial Fibrillation
The aim of this prospective randomized double-blind study was to compare the efficacy of new pharmaceutical composition containing botulinum toxin injection in epicardial fat pads for preventing recurrences of atrial…
- Trial name
- NCT02982434
- Testing
- Pharmaceutical composition containing botulinum toxin, 0.9% normal saline, Coronary artery bypass grafting
- Where
- 2 sites in Russia
- Volunteers
- 180 people
- Sponsor
- Meshalkin Research Institute of Pathology of Circulation
Coronary Artery Bypass Grafting, Postoperative Acute Kidney Injury
Trajectory-Based Phenotyping After Coronary Artery Bypass Surgery
Coronary artery bypass grafting is a commonly performed heart surgery, but patients may have different risks for postoperative complications even when their preoperative risk scores are similar.
- Conditions
- Coronary Artery Bypass Grafting, Postoperative Acute Kidney Injury, Postoperative Complications, Risk Stratification
- Trial name
- NCT07598682
- Testing
- Early Postoperative Phenotype Classification
- Where
- Turkey (Türkiye)
- Volunteers
- 1,000 people
- Sponsor
- Bursa Sevket Yilmaz Training and Research Hospital
Coronary Artery Bypass Graft Surgery (CABG), Patient Education
Determining the Consistency Between Nurses and Artificial Intelligence (ChatGPT-5) in Delivering Scenario-Based Discharge Education to Coronary Artery Bypass Graft Patients: A Methodological Study
This methodological study aims to determine the level of agreement between nurses and an artificial intelligence system (ChatGPT-4.0) in providing scenario-based discharge education for patients who have undergone coronary artery…
- Trial name
- CABG-AI-EDU (NCT07263724)
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Hasan Kalyoncu University
Aortic Valve Disease
Use of Transvenous Pacing Wire During Minimally Invasive Port Access Aortic Valve Surgery
The study is being done to determine if the Endovent pulmonary catheter kit, used for port access surgery, can be used as a passageway for a pacing wire.
- Trial name
- NCT01631188
- Testing
- Minimally Invasive Aortic Valve, Minimally Invasive Aortic Valve Surgery, Manipulation in OR surgical technique
- Volunteers
- 100 people
- Sponsor
- Rutgers, The State University of New Jersey
Renal Failure, Coronary Artery Disease
Prevent Cardiac Surgery Associated AKI Trial
Prevent CSA-AKI (Cardiac Surgery Associated Acute Kidney Injury) trial is a double blinded randomized controlled trial, 242 patients undergoing elective cardiopulmonary bypass surgery (CPB)will either receive a placebo or daily…
- Conditions
- Renal Failure, Coronary Artery Disease, Surgery, Surgery-Complications
- Trial name
- NCT06620523
- Testing
- CoQ10 1200 mg orally with Glutathione 1000 mg orally
- Where
- United States
- Volunteers
- 242 people
- Sponsor
- George Washington University
Coronary Artery Disease, Myocardial Infarction
Outcome After Coronary Artery Bypass Grafting
The E-CABG registry is a multicenter, European registry collecting data on the preoperative characteristics, treatment strategies and outcome of patients undergoing isolated coronary artery bypass grafting (CABG).
- Conditions
- Coronary Artery Disease, Myocardial Infarction, Angina Pectoris
- Trial name
- E-CABG (NCT02319083)
- Testing
- Coronary artery bypass surgery
- Where
- Finland
- Volunteers
- 4,000 people
- Sponsor
- University of Oulu
Coronary Artery Bypass Grafting, Coronary Artery Disease
Radial Artery Assessment in Surgical Coronary Revascularisation
The goal of this observational study is to learn about how screening tests inform the radial artery (RA) suitability for harvesting and coronary bypass grafting in adults with ischaemic heart disease.
- Trial name
- NCT06433960
- Testing
- Modified Allen Test, Pulse-oximetry guided Modified Allen Test, Barbeau Test
- Where
- 2 sites in United Kingdom
- Volunteers
- 77 people
- Sponsor
- Papworth Hospital NHS Foundation Trust
Coronary Artery Disease
Fractional Flow Reserve Versus Angiography for Multivessel Evaluation (FAME) 3 Extended
Coronary artery disease, or narrowing of the blood vessels that provide blood to the heart, is the most common cause of death in the United States and can be treated with either coronary bypass surgery or coronary stent…
- Trial name
- NCT07308860
- Testing
- FFR-guided PCI, CABG
- Where
- United States
- Volunteers
- 1,500 people
- Sponsor
- Stanford University
Cardiopulmonary Bypass
Maintaining Mechanical Ventilation During Cardiopulmonary Bypass for Cardiac Surgery
The main objective of this study is to measure the incidence of postoperative infections in 2 groups of patients: one group of patients ventilated and one group of patients without mechanical ventilation during cardiopulmonary…
- Trial name
- VECAR (NCT03372174)
- Testing
- Maintaining mechanical ventilation during surgery, Absence of mechanical ventilation during surgery
- Where
- 6 sites in France
- Volunteers
- 1,401 people
- Sponsor
- Rennes University Hospital
Cardio-pulmonary Bypass, Cardiovascular Diseases
Dietary Supplements in Patients With Coronary Artery Bypass Grafting for Improving the Quality of Healthcare Delivery.
Cardiovascular disease (CVD) remains the leading cause of death worldwide. Prevention of CAD by targeting modifiable factors remains a key public health priority. L-Ascorbic Acid (Vitamin C - Vit.
- Conditions
- Cardio-pulmonary Bypass, Cardiovascular Diseases, Omega-3 Polyunsaturated Fatty Acids, Omega-3 Supplementation
- Trial name
- NCT06995586
- Testing
- Vitamin C, Omega 3 PUFA (EPO/DHA), Lignin, Lactulose
- Where
- Cyprus
- Volunteers
- 108 people
- Sponsor
- Nicosia General Hospital
Coronary Arterial Disease (CAD)
Shockwave Intervention for Enhanced Wound Healing in No-touch Pedicle Saphenous Vein Graft Harvesting for Coronary Artery Bypass Grafting
The aim of this trial is to apply shockwaves to the leg wound after saphenous vein harvesting and closure in order to reduce the occurrence of postoperative wound healing complications following coronary artery bypass grafting…
- Trial name
- SHIELDS-CABG (NCT07068776)
- Testing
- Shockwave treatment
- Where
- Austria
- Volunteers
- 120 people
- Sponsor
- Medical University Innsbruck
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