Clinical trials: Coronary Embolism
Acute Pulmonary Embolism
Incorporating Healthy Living Strategies to Aid in Recovery After Acute Pulmonary Embolism
The purpose of the ERAsE-PE study is to determine whether two different healthy living strategies (along with anticoagulation) might aid in recovery after a patient is hospitalized for pulmonary embolism.
- Trial name
- ERASE-PE (NCT06784492)
- Testing
- Healthy Living Intervention-1, Healthy Living Intervention-2
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Rochester
Atrial Fibrillation, Venous Thromboses
Pharmacogenetic Dosage Algorithm for Acenocoumarol
The use of coumarins has been a challenge for doctors because of its narrow therapeutic range and they show great inter and intra-individual variability in the dose necessary to achieve an international normalized ratio (INR)…
- Conditions
- Atrial Fibrillation, Venous Thromboses, Cardiac Valve Disease
- Trial name
- NCT03015025
- Testing
- Acenocoumarol
- Where
- Spain
- Volunteers
- 340 people
- Sponsor
- Instituto de Investigación Hospital Universitario La Paz
Atrial Fibrillation, Venous Thromboembolism
Reinitiation of Anticoagulation After Temporary Withdrawal of Vitamin K Antagonist
It is not known how to best restart warfarin after temporary withdrawal. Participants will be randomized to two groups. Group 1 will restart warfarin at their usual maintenance dose, group 2 will restart warfarin at double their…
- Conditions
- Atrial Fibrillation, Venous Thromboembolism, Heart Valve Disease, Surgery
- Trial name
- DOSIDO (NCT01348074)
- Testing
- Double dose
- Where
- Canada
- Volunteers
- 104 people
- Sponsor
- McMaster University
Pulmonary Hypertension, Valvular Heart Disease
Evaluating Right Ventricular (RV) Size and Function Using the Upper Valley RV Algorithm and Novel Imaging Modalities
The primary purpose of this study is to evaluate the diagnostic performance of three methods for measuring right ventricular size and function including the Philips Novel RV quantification technologies (RV Heart Model volumetric…
- Conditions
- Pulmonary Hypertension, Valvular Heart Disease, Congenital Heart Disease, Congestive Heart Failure
- Trial name
- UVRV (NCT03935178)
- Testing
- Measuring Right Ventricular Size and Function
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Acute Coronary Syndrome
Antithrombotic Effects of Ticagrelor Versus Clopidogrel
The purpose of this study is to determine whether treatment with ticagrelor (plus aspirin and bivalirudin) is more effective than treatment with clopidogrel (plus aspirin and bivalirudin).
- Trial name
- NCT01642238
- Testing
- Ticagrelor + ASA + Bivalirudin, Clopidogrel + ASA + Bivalirudin
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Juan J Badimon
Acute Coronary Syndrome, Heart Failure
A Survey of Hospitalizations in Cardiology Units in Sub-Saharan Africa
FEVRIER study is an observatory of hospitalizations in cardiology units in sub-Saharan Africa.
- Conditions
- Acute Coronary Syndrome, Heart Failure, Syncope, Stroke
- Trial name
- FEVRIER (NCT03231449)
- Testing
- observation of current care
- Where
- 20 sites in Benin, Burkina Faso and 11 more
- Volunteers
- 5,000 people
- Sponsor
- Cardiologie et Développement
Atrial Fibrillation, Thromboembolism
AMPLATZER™ LAA Occluder Post Approval Study (PAS)
The aim of this multicenter, non-randomized observational post-approval is to compile real world outcome data on the use of an AMPLATZER LAA Occluder in subjects with non-valvular atrial fibrillation (NVAF).
- Conditions
- Atrial Fibrillation, Thromboembolism, Stroke
- Trial name
- NCT02964208
- Testing
- AMPLATZER™ LAA Occluder
- Where
- 22 sites in Argentina, Belgium and 5 more
- Volunteers
- 520 people
- Sponsor
- Abbott Medical Devices
Atrial Fibrillation, Recurrent Venous Thromboembolism
Real-life Clinical Outcomes of Direct Oral Anticoagulants (MACACOD)
MACACOD is a clinical record in the usual clinical practice of direct oral anticoagulants (dabigatran, rivaroxaban, apixaban and edoxaban).
- Trial name
- MACACOD (NCT04042155)
- Testing
- dabigatran, rivaroxaban, apixaban or edoxaban
- Where
- Spain
- Volunteers
- 1,600 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Complications of Atrial Fibrillation
New Causes and Predictors for the Development of Atrial Fibrillation and Its Complications
Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia and its prevalence increases with aging of the population.
- Trial name
- NCT01863979
- Volunteers
- 500 people
- Sponsor
- Rambam Health Care Campus
Oral Anticoagulation, Deep Venous Thrombosis
Pharmacodynamic Drug Interaction Between Warfarin and Amoxicillin-clavulanic Acid
Several case reports indicate that the use of the antibiotic combination amoxicillin and clavulanic acid (AM-CLAVAC) can interact with warfarin pharmacodynamics.
- Conditions
- Oral Anticoagulation, Deep Venous Thrombosis, Atrial Fibrillation, Pulmonary Embolism
- Trial name
- INWARA (NCT00603317)
- Where
- France
- Volunteers
- 13 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Acute Coronary Syndrome, Venous Thromboembolism
The Effect of Reduced Dose of Enoxaparin on the Outcomes of Treatment With Enoxaparin
We hypothesize that reduced dose of enoxaparin in elderly patients will result in reduced proportion of patients with therapeutic anti Xa activity and reduced clinical efficacy.
- Conditions
- Acute Coronary Syndrome, Venous Thromboembolism, Atrial Fibrillation, Hypercoagulability
- Trial name
- NCT00354796
- Where
- Israel
- Volunteers
- 500 people
- Sponsor
- Hadassah Medical Organization
Heart Failure, Cardiomyopathies
Multimodal Physiologic State Intelligence Study
The OMNIPHYS study will investigate whether multimodal ultrasound and other routinely collected clinical and physiologic data can be combined with artificial intelligence to characterize changes in a person's physiologic state…
- Conditions
- Heart Failure, Cardiomyopathies, Pulmonary Hypertension, Myocarditis; Acute or Subacute
- Trial name
- OMNIPHYS (NCT07814118)
- Testing
- OMNIPHYS Multimodal Ultrasound Imaging System
- Where
- United States
- Volunteers
- 25,000 people, healthy volunteers welcome
- Sponsor
- Truway Health, Inc.
Cardiopulmonary Bypass, Congenital Defects
Aprotinin in Neonates Undergoing Cardiopulmonary Bypass
This is a retrospective chart review study. The purpose of this study is to review our experience at Children's Healthcare of Atlanta in neonates receiving aprotinin.
- Conditions
- Cardiopulmonary Bypass, Congenital Defects, Hemostasis
- Trial name
- NCT00469742
- Where
- United States
- Volunteers
- 290 people
- Sponsor
- Children's Healthcare of Atlanta
Atrial Fibrillation, Left Atrial Thrombosis
Left Atrial Thrombus Reduction - Effect of Dabigatran Versus Phenprocoumon
This is a single-center, randomized, two treatment groups, open, phase IV clinical study in subjects with atrial fibrillation and left atrial thrombus.
- Trial name
- NCT02591225
- Testing
- Dabigatranetexilate, Phenprocoumon
- Where
- Germany
- Volunteers
- 40 people
- Sponsor
- University of Ulm