Clinical trials: Coronary Heart Disease Risk Reduction
Heart Failure, Heart Failure With Reduced Ejection Fraction
AI-ECG for Time-Resolved Prediction of HFrEF
This study aims to develop and validate a deep learning-based electrocardiogram (ECG) model for predicting the future risk of heart failure with reduced ejection fraction (HFrEF).
- Conditions
- Heart Failure, Heart Failure With Reduced Ejection Fraction, Left Ventricular Dysfunction, Cardiac Remodeling
- Trial name
- NCT07519434
- Where
- China
- Volunteers
- 286,709 people, healthy volunteers welcome
- Sponsor
- Shanghai Zhongshan Hospital
Atherosclerotic Cardiovascular Disease, Coronary Artery Disease
The Young Heart Study
The purpose of our project is to better understand the characteristics of the young patients with coronary artery disease presenting for cardiac catheterization at our institution and to put forth a program to optimize their risk…
- Trial name
- NCT04462159
- Testing
- Risk Reduction Program
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Northwell Health
AKI, CHD - Congenital Heart Disease
NO During CPB in Neonates to Reduce Risk of AKI
Acute kidney injury (AKI) following cardiac surgery for congenital heart defects (CHD) in children affects up to 60% of high risk-patients and is a major cause of both short- and long-term morbidity and mortality.
- Conditions
- AKI, CHD - Congenital Heart Disease, Surgery
- Trial name
- NCT04216927
- Testing
- Nitric Oxide, Oxygen
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Heart Failure, Morality
Optimized Peak VO2 in Predicting Advanced HF
The ability and timely selection of severe heart failure (HF) patients for cardiac transplantation and advanced HF therapy is challenging. Peak VO2 by cardiopulmonary exercise test (CPET) was used for transplant listing.
- Conditions
- Heart Failure, Morality, Transplant; Failure, Heart
- Trial name
- NCT05212649
- Testing
- cardiopulmonary exercise test
- Where
- Taiwan
- Volunteers
- 377 people
- Sponsor
- Chang Gung Memorial Hospital
Hypertension (HTN)
Assessing the Feasibility of the "Heart Care Pairs" Intervention
The researchers will invite 30 patients in primary care who have high blood pressure to participate in this health program with a supportive partner of their choosing (these will be the "participant pairs").
- Trial name
- NCT07760350
- Testing
- Dyadic lifestyle intervention for CVD risk reduction
- Where
- United States
- Volunteers
- 85 people
- Sponsor
- University of Alabama at Birmingham
Atrial Fibrillation, Atrial Flutter
A Study to Determine if Identification of Undiagnosed Atrial Fibrillation in People at Least 70 Years of Age Reduces the Risk of Stroke
The purpose of this study is to determine if an AF detection intervention in men and women at least 70 years of age with undiagnosed atrial fibrillation (AF) or atrial flutter (AFL) reduces the person-years incidence rate of…
- Trial name
- GUARD-AF (NCT04126486)
- Testing
- Zio®XT Monitor
- Where
- 176 sites in United States
- Volunteers
- 11,931 people
- Sponsor
- Bristol-Myers Squibb
Heart Disease Risk Factors
mHealth-supported Coach
A randomised controlled trial to evaluate the effects of a personalised mHealth-supported coach programme in the middle-aged group with stroke risk.
- Trial name
- NCT05422729
- Testing
- mHealth-supported coaching, Conventional Health coaching
- Where
- Hong Kong
- Volunteers
- 164 people
- Sponsor
- Food and Health Bureau, Hong Kong
Cardiovascular Diseases, Heart Diseases
Enhancing Support for Women at Risk for Heart Disease
To test a practical, theory-based intervention to achieve long-term behavior change for postmenopausal women with Type 2 diabetes at high risk for developing coronary heart disease (CHD).
- Conditions
- Cardiovascular Diseases, Heart Diseases, Coronary Disease, Coronary Heart Disease Risk Reduction
- Trial name
- NCT00142701
- Testing
- diet, physical activity, stress management
- Sponsor
- Oregon Research Institute
Hypercholesterolemia, Cardiovascular Disease
Barley Protein and CVD
The Question posed is: Does an barley protein concentrate have health benefits similar to those demonstrated for soy protein foods which would justify the use of the non-fiber components of barley as functional food ingredients?…
- Conditions
- Hypercholesterolemia, Cardiovascular Disease, Diet Therapy
- Trial name
- NCT00334308
- Testing
- Barley protein bread or control (casein) bread
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Cardiovascular Diseases, Heart Diseases
Stanford Five-City Multifactor Risk Reduction Study
To conduct a large-scale demonstration and education project designed to evaluate the feasibility and effectiveness of long-term community health education directed toward lowering cardiovascular disease risk, morbidity, and…
- Conditions
- Cardiovascular Diseases, Heart Diseases, Atherosclerosis, Coronary Disease
- Trial name
- NCT00005143
- Volunteers
- 2,504 people
- Sponsor
- Stanford University
Cardiovascular Risk Factor, Stress
Stress-reduction Wellness Program for Midlife Black Women (B-SWELL)
This research study examines the unique cultural and gender-based factors that influence how midlife Black women experience stress and incorporate healthy lifestyle behaviors into daily life.
- Conditions
- Cardiovascular Risk Factor, Stress, Self Efficacy, Depressive Symptoms
- Trial name
- B-SWELL (NCT04404478)
- Testing
- B-SWELL: Midlife Black Women's Stress Reduction Wellness Program, WE: Wellness program for Midlife Black Women
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- University of Cincinnati
Coronary Artery Disease, Metabolic Syndrome
Super-Rehab: Can we Achieve Coronary Artery Disease Regression?
The Super Rehab: Can we Achieve Coronary Artery Disease Regression? (a feasibility study) proposes to test the use of a novel lifestyle intervention (Super Rehab), in addition to standard care, for patients with both coronary…
- Trial name
- NCT05563584
- Testing
- Super Rehab
- Where
- United Kingdom
- Volunteers
- 31 people
- Sponsor
- Royal United Hospitals Bath NHS Foundation Trust
Myocardial Infarction, Risk Reduction
The Perfect-CR Implementation Study
The goal of this open-label cluster-randomized effectiveness-implementation hybrid trial is to study whether a) audit and feedback of cardiac rehabilitation service delivery within a national quality registry and b) structured…
- Trial name
- NCT05889416
- Testing
- Audit and feedback through a quality registry, Implementation support
- Where
- Sweden
- Volunteers
- 75 people
- Sponsor
- Skane University Hospital
Acute Kidney Injury, Congenital Heart Disease
Nitric Oxide During Cardiopulmonary Bypass in Neonates to Reduce Risk of Acute Kidney Injury
Acute kidney injury following cardiac surgery for congenital heart defects in children is a major cause of both short- and long-term morbidity and mortality, affecting up to 60% of high risk patients.
- Trial name
- NCT04259684
- Testing
- gases Nitric Oxide (gNO)
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Atrial Fibrillation, Hypertension
Mindfulness to Reduce Ambulatory Hypertension in Atrial Fibrillation
The aim of this study is to evaluate the effectiveness of a 16 week mindfulness-based coaching program compared to a cardiovascular risk reduction education program.
- Conditions
- Atrial Fibrillation, Hypertension, Mindfulness, Cardiovascular Risk Reduction
- Trial name
- AF (NCT03910192)
- Testing
- Mindfulness-based coaching, Dietary cardiovascular risk reduction coaching
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- York University
Coronary Artery Disease, Myocardial Infarction
Aspirin Response in High Risk Patients With Coronary Artery Disease
Previous studies indicate that patients with cardiovascular disease have a variable response to aspirin. Despite treatment with aspirin a large number of patients suffer a myocardial infarction.
- Conditions
- Coronary Artery Disease, Myocardial Infarction, Diabetes Mellitus, Renal Insufficiency, Chronic
- Trial name
- NCT01383304
- Where
- Denmark
- Volunteers
- 906 people
- Sponsor
- University of Aarhus
Cardiovascular Diseases, Hypertension
Hypertension Education and Treatment Partnership for Reducing Ethnic Differences in the Risk of Cardiovascular Disease
The purpose of this study is to improve hypertension outcomes in racial and ethnic minorities.
- Conditions
- Cardiovascular Diseases, Hypertension, Heart Diseases
- Trial name
- NCT00101504
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Acute Coronary Syndrome
Healthy Heart Habits-2
Sixty adults who have experienced acute coronary syndrome within the past 2-12 months from three states (Rhode Island, North Carolina, Minnesota) will be randomized to either (1) a coaching program for depressed mood and health…
- Trial name
- HHH-2 (NCT06440278)
- Testing
- Behavioral Activation for Health and Depression (BA-HD), Enhanced Usual Care
- Where
- 3 sites in United States
- Volunteers
- 39 people
- Sponsor
- The Miriam Hospital
Atrial Fibrillation
Apixaban Dose Reduction in Patients With Elevated Drug Levels
Apixaban is an anticoagulant which is increasingly being used to prevent stroke in atrial fibrillation (AF). Phase III clinical trials have demonstrated that apixaban is efficacious and safe for the overall AF population…
- Trial name
- ADREL (NCT02809469)
- Testing
- apixaban dose reduction
- Where
- Canada
- Volunteers
- 120 people
- Sponsor
- Hamilton Health Sciences Corporation
Cardiovascular Diseases, Coronary Heart Disease Risk Reduction
Providers for Smoking Prevention Programs
To conduct a randomized controlled smoking prevention trial to evaluate quality of implementation and effectiveness, as a function of provider type (school teacher vs. nurse) and training (mediated vs. interactive).
- Conditions
- Cardiovascular Diseases, Coronary Heart Disease Risk Reduction, Heart Diseases, Lung Diseases
- Trial name
- NCT00005331
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)