Clinical trials: Coronary Physiology
Cardiovascular Diseases, Atherosclerosis
Aspirin Dose and Atherosclerosis in Patients With Heart Disease
The purpose of the study is to test higher versus lower doses of aspirin on markers of atherosclerosis in patients who have had a heart attack.
- Conditions
- Cardiovascular Diseases, Atherosclerosis, Myocardial Infarction
- Trial name
- TAD (NCT00272337)
- Testing
- Aspirin
- Where
- 2 sites in United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Florida Atlantic University
Hyperkyphosis
Postural Management of Hyperkyphosis in Cardiac Rehab Patients
The goal of this clinical trial is to evaluate the efficacy of a home-based exercise program in managing hyperkyphosis, and its impact on physical performance and pulmonary function among cardiac rehabilitation patients.
- Trial name
- NCT06563882
- Testing
- Home-based exercise program, No intervention
- Where
- Israel
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Breathing Exercises
Comparative Effects of ACBT and Diaphragmatic Breathing on Pulmonary Function and Sputum Diary After CABG
To compare the effects of active cycle of breathing technique and diaphragmatic breathing on pulmonary functions and sputum diary after coronary artery bypass graf
- Trial name
- NCT05936788
- Testing
- Active cycle of breathing technique, diaphragmatic breathing
- Where
- Pakistan
- Volunteers
- 32 people
- Sponsor
- Riphah International University
Cardiac Rehabilitation
Comparison of Open Heart Surgery Patients With Forward Head Posture With and Without Perioperative Therapeutic Exercise
Comparison of open heart surgery patients with forward head posture with and without perioperative therapeutic exercise on craniovertebral angle, pulmonary function, balance and quality of life
- Trial name
- NCT05967780
- Testing
- Group A: Patients with FHP receiving standard cardiac rehabilitation, Group B: Patients with FHP receiving standard cardiac rehabilitation + therapeutic exercises, Group C: Patients without FHP receiving standard cardiac rehabilitation
- Where
- Pakistan
- Volunteers
- 48 people
- Sponsor
- Health Education Research Foundation (HERF)
Dilated Cardiomyopathy
Simvastatin Therapy in Patients With Dilated Cardiomyopathy.
Dilated cardiomyopathy (DCM) is the most common childhood cardiomyopathy and is associated with significant early morbidity and mortality. About half of patients die or require heart transplantation within 5 years of diagnosis.
- Trial name
- SavDCM (NCT03775070)
- Testing
- Simvastatin
- Where
- Taiwan
- Volunteers
- 8 people
- Sponsor
- National Taiwan University Hospital
Heart Failure, Vitamin D Deficiency
Effect of Vitamin D Supplementation in Patients With Heart Failure and Vitamin D Deficiency
The purpose of this study is to determine the effects of vitamin D supplementation in patients with heart failure and vitamin D deficiency on ventricular function, inflammatory cytokines, brain natriuretic peptide, lipid profile…
- Trial name
- NCT02087683
- Testing
- Vitamin D Supplementation
- Where
- Mexico
- Volunteers
- 60 people
- Sponsor
- Instituto Tecnologico y de Estudios Superiores de Monterey
Pulmonary Disease, Chronic Obstructive
Beta-Blockers for the Prevention of Acute Exacerbations of Chronic Obstructive Pulmonary Disease
This is a multicenter, prospective, randomized, double-blind, placebo-controlled trial that will enroll 1028 patients with at least moderately severe COPD over a three year period and follow them at regular intervals for one…
- Trial name
- NCT02587351
- Testing
- Metoprolol succinate
- Where
- 27 sites in United States
- Volunteers
- 532 people
- Sponsor
- University of Minnesota
Respiratory Complications, Diaphragmatic Excursion
Acute Effect of the Thoraco-abdominal Rebalance Method Postoperative Cardiac Surgery
Introduction: The thoracoabdominal rebalancing (TAR) method aims to promote diaphragmatic juxtaposition, in addition to seeking to increase respiratory muscle strength and adjust muscle tone.
- Conditions
- Respiratory Complications, Diaphragmatic Excursion, Pulmonary Spirometry
- Trial name
- NCT06814951
- Testing
- TAR Method, Conventional physiotherapy
- Where
- Brazil
- Volunteers
- 26 people
- Sponsor
- Instituto de Cardiologia do Rio Grande do Sul
CT Images
Incisive CT Clinica Trial Protocol
The purpose of this study was to evaluate whether the new features of Incisive CT: Precise Image, (PI) and Precise Cardiac (PC) had the expected effectiveness
- Trial name
- NCT05020262
- Testing
- CT Image reconstruction
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Philips Healthcare (Suzhou) Co., Ltd.
Heart Failure With Preserved Ejection Fraction (HFPEF)
Effects of a Multicomponent Training Program on Cardiac Function, Skeletal Muscle Metabolism, Functional Capacity, and Quality of Life in Patients With HFpEF: SENSORFIT-4HEART Study
Heart failure with preserved ejection fraction (HFpEF) is a complex syndrome with increasing incidence and poor prognosis, accounting for up to 50% of heart failure cases.
- Trial name
- SENSORFIT-4HEA (NCT07251361)
- Testing
- Supervised training
- Where
- Spain
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Universidad Pública de Navarra
Healthy
Myocardial Fibrosis, Function and Aging
In normal ageing, the impact of myocardial fibrosis on myocardial function is unclear as diastolic function is reported to change according to age.
- Trial name
- MARVEL (NCT03064503)
- Testing
- Blood sampling, MRI, Skin auto-fluorescence
- Where
- France
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Congenital Heart Disease, Fontan
Effects of Pulmonary Vasodilation Upon VA Coupling in Fontan Patients
The study involves documenting the effects of inhaled nitric oxide upon ventricular-arterial coupling in patients with congenital heart disease and passive pulmonary blood flow.
- Trial name
- NCT01607983
- Testing
- inhaled nitric oxide
- Where
- United States
- Sponsor
- University of California, San Francisco
Heart Failure
Balance and Executive Function in Middle-age and Older Patients With Heart Failure in Post-Acute Care Program
This trial is a single-center clinical trial in Taiwan with an expected enrollment of 60 people in Taiwan. The purpose of this trial is to compare the performance of middle-aged and elderly patients with subacute heart failure…
- Trial name
- NCT06463496
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Chang Chia-Jung
Pulmonary Hypertension
Acute Exposure of Simulated Hypoxia on Pulmonary Artery Pressure and Right Heart Function (Echo)
Randomized crossover trial in patients with Pulmonary Hypertension (PAH, CTEPH) to assess the acute response to simulated altitude (FiO2:15.1, equivalent to 2500m above sea level) on pulmonary artery pressure and right heart…
- Trial name
- NCT03637088
- Testing
- Simulated Altitude (FiO2: 15.1%)
- Where
- Switzerland
- Volunteers
- 28 people
- Sponsor
- University of Zurich
Persistent Atrial Fibrillation, Congestive Heart Failure Due to Left Ventricular Systolic Dysfunction
Atrial Fibrillation Ablation Compared to Rate Control Strategy in Patients With Impaired Left Ventricular Function
Atrial fibrillation (AF) and congestive heart failure (CHF) are two epidemics that share several physiopathological links. CHF patients present a significantly increased risk of developing AF and the related detrimental…
- Trial name
- AFARC-LVF (NCT02509754)
- Testing
- Atrial fibrillation catheter ablation, Rate control
- Volunteers
- 180 people
- Sponsor
- University of Turin, Italy
Atrial Fibrillation (AF)
Electronic Blood Pressure Monitor for Atrial Fibrillation Detection
Study name: Study on the Effectiveness of Atrial Fibrillation Screening Using Electronic Blood Pressure Monitor with Atrial Fibrillation Detection Function Objective: This study compares an electronic blood pressure monitor…
- Trial name
- NCT06931288
- Testing
- Blood pressure monitor, Single-lead ECG
- Where
- China
- Volunteers
- 20,000 people, healthy volunteers welcome
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Failing Fontan Physiology, Failing Fontan
The Destination Therapy Evaluation for Failing Fontan Study
Purpose: The purpose of the Destination Therapy Evaluation for Failing Fontan Study (DEFINe Study) is to perform a single center physician-investigator led feasibility study to initiate examination of the safety and efficacy of…
- Conditions
- Failing Fontan Physiology, Failing Fontan, Single-ventricle, Single-ventricle Fontan
- Trial name
- DEFINe (NCT01149603)
- Testing
- HeartMate II Ventricular Assist Device
- Where
- United States
- Sponsor
- Timothy Icenogle, MD
Coronary Arteriosclerosis
The Effect of Exercise on Stem Cell Mobilization and Heart Function in Patients Undergoing Cardiac Rehabilitation
This study will look at the effect of a cardiac rehabilitation exercise program on release of stem cells from the bone marrow and on heart function.
- Trial name
- NCT00053456
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
BPH
Transthoracic Echocardiographic Evaluation of the Cardiac Function During Transurethral Resection of Prostate in Elderly Patients
Transurethral resection of the prostate (TURP) is a standard surgical treatment for benign prostatic hyperplasia (BPH). Non-conductive irrigation fluid is used to maintain good visibility of the operating field during resection…
- Trial name
- NCT02288780
- Volunteers
- 2 people
- Sponsor
- Yonsei University
Heart Disease Congenital Complex
Effect of Postop Steroids on Cardiovascular/Respiratory Function in Neonates Undergoing Cardiopulmonary Bypass
This protocol is designed to offer insight into critical illness related corticosteroid insufficiency and steroid supplementation in neonates undergoing cardiac surgery with cardiopulmonary bypass by administering exogenous…
- Trial name
- NCT01595386
- Testing
- Hydrocortisone, Normal Saline
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Alabama at Birmingham