Clinical trials: Coronary Stent Occlusion
Coronary Artery Disease, Myocardial Ischemia
BIOFLOW-III Israel Satellite Registry
BIOTRONIK - SaFety and Performance Registry for a diabetic patient population with the .bimus Eluting Orsiro Stent System Within daily clinical practice - III
- Conditions
- Coronary Artery Disease, Myocardial Ischemia, Diabetes Mellitus Type 1 or 2
- Trial name
- NCT01895712
- Where
- 6 sites in Israel
- Volunteers
- 120 people
- Sponsor
- BIOTRONIK Israel
Stents, Coronary Artery Disease
First-in-Man Study: Safety and Efficacy of INC-1 Bare Metal Stent in the Novo Coronary Lesions.
This is a First In Man study with the aim to know the safety and effectiveness of a novel bare metal stent (INC-1) in the treatment of de novo coronary lesions in patients with stable coronary angina and unique coronary lessions.
- Conditions
- Stents, Coronary Artery Disease, Angioplasty, Humans
- Trial name
- NCT03375411
- Testing
- Stent INC1
- Where
- Mexico
- Sponsor
- Instituto Nacional de Cardiologia Ignacio Chavez
Coronary Artery Disease, Myocardial Ischemia
Multivessel TALENT
Multivessel TALENT is a prospective, randomized, multi-center study comparing clinical outcomes between SUPRAFLEX Cruz and SYNERGY in approximately 1550 patients with de-novo three vessel disease undergoing percutaneous coronary…
- Conditions
- Coronary Artery Disease, Myocardial Ischemia, Coronary Disease, Heart Diseases
- Trial name
- NCT04390672
- Testing
- SUPRAFLEX Cruz, SYNERGY
- Where
- Ireland
- Volunteers
- 1,550 people
- Sponsor
- National University of Ireland, Galway, Ireland
Coronary Artery Disease
Short-term Dual Antiplatelet Therapy After Deployment of Bioabsorbable Polymer Everolimus-eluting Stent
To compare the clinical outcomes of P2Y12 antagonist monotherapy with aspirin plus P2Y12 antagonist following 3-month of DAPT in patients undergoing PCI with bioabsorbable polymer Everolimus-eluting stents (Synergy®)
- Trial name
- NCT03447379
- Testing
- P2Y12 antagonist monotherapy, Aspirin plus P2Y12 antagonist
- Where
- South Korea
- Volunteers
- 1,452 people
- Sponsor
- Gangnam Severance Hospital
Stable Angina, Coronary Artery Disease
OCT-Guided Stent Optimization for Short-Duration Dual Antiplatelet Therapy in Stable Angina
This study aims to evaluate whether the use of optical coherence tomography (OCT), an advanced intravascular imaging tool, can improve stent implantation results and make it possible to shorten the duration of dual antiplatelet…
- Trial name
- COMFORT-SHORT (NCT07198529)
- Testing
- Short DAPT, Standard DAPT, Extended DAPT
- Where
- South Korea
- Volunteers
- 130 people
- Sponsor
- Korea University Guro Hospital
Coronary Artery Disease, High Bleeding Risk Patients
ULTRA LONG: BioFreedom Ultra
The goal of this Prospective, multi-center, open-label single-arm study is to Assess the Safety and Effectiveness of additional sizes of the BioFreedom Ultra CoCr Biolimus A9 coated coronary stent system in Patients at high risk…
- Trial name
- NCT05643430
- Testing
- BioFreedom Ultra
- Where
- 9 sites in France, United Kingdom
- Volunteers
- 86 people
- Sponsor
- Biosensors Europe SA
Coronary Artery Disease, Coronary Occlusion
Safety and Efficacy of Drug-Coated Balloon Angioplasty for the Treatment of Chronic Total Occlusions
The purpose of this study is to investigate the safety and efficacy of drug-coated balloon angioplasty for the treatment of chronic total occlusions patients with chronic total occlusion (CTO) lesion.
- Conditions
- Coronary Artery Disease, Coronary Occlusion, Percutaneous Coronary Intervention, Chronic Total Occlusion of Coronary Artery
- Trial name
- NCT04744571
- Testing
- aspirin, betaloc, atorvastatin, rosuvastatin, clopidogrel, ticagrelor, coronary wires. or coronary balloons, drug-coated balloon
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Beijing Anzhen Hospital
Coronary Artery Disease
Stenting With or Without Coating Compared With Angioplasty in Non-benestent Disease
The purpose of this study is to evaluate the clinical and angiographic outcome of implantation of stents eluting or not eluting Sirolimus in patients with complex coronary artery lesions suitable for percutaneous coronary…
- Trial name
- NCT00192881
- Testing
- Bx Sonic & Cypher stent from Cordis
- Where
- Denmark
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Coronary Artery Disease, Coronary Stent Occlusion
DXR Stent for Vascular Healing and Thrombus Formation: OCT Study
The purpose of this study is to evaluate the efficacy of a novel dual drug-eluting stent (DXR stent), which slowly releases both cilostazol and paclitaxel, for strut coverage, malapposition, and thrombus formation, assessed by an…
- Trial name
- NCT02932995
- Where
- 6 sites in South Korea
- Volunteers
- 60 people
- Sponsor
- Chung-Ang University
Coronary Artery Disease
1-month vs 12-month DAPT for ACS Patients Who Underwent PCI Stratified by IVUS: IVUS-ACS and ULTIMATE-DAPT Trials
Prospective, multicenter, randomized, double-blind, placebo-controlled trials.
- Trial name
- NCT03971500
- Testing
- AntiPlatelet therapy, Percutaneous coronary intervention
- Where
- China
- Volunteers
- 3,710 people
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
Coronary Artery Disease
A Postmarket Clinical Trial for EXCROSSAL Stent in CAD Patients With 3-month DAPT or 12-month DAPT
1. Prospective, randomized, multicenter clinical study 2. This is a post-marketing clinical study to evaluate whether it will affect the safety event when it is used in different treatment ways.
- Trial name
- NCT03716011
- Testing
- EXCROSSAL
- Where
- China
- Volunteers
- 2,700 people
- Sponsor
- JW Medical Systems Ltd
Coronary Artery Disease
Multicenter Comparison of Early and Late Vascular Responses to Everolimus-eluting Cobalt-CHromium Stent and Platelet AggregatioN studIeS for TreatMent of Acute Myocardial InfarctionTreatment of ST-elevation Acute Myocardial Infarction
To treat patients with acute myocardial infarction, primary percutaneous coronary intervention (PCI) will be performed with the use of an everolimus-eluting cobalt- chromium stent (everolimus-eluting stent: EES, Xience Prime…
- Trial name
- MECHANISM-AMI (NCT02014753)
- Testing
- cobalt-chromium everolimus-eluting stent (CoCr-EES)
- Where
- Japan
- Volunteers
- 100 people
- Sponsor
- Iwate Medical University
Coronary Artery Disease
A Trial Comparing a Paclitaxel Eluting Stent With Biodegradable Polymer Versus a Bare Metal Stent
The success of stent implantation has led to the increasingly widespread use of them in the treatment of coronary artery disease (Sigwart, Serruys, Fischman)and although stent restenosis is still a limit for this therapeutic mode…
- Trial name
- EUCATAX (NCT00825279)
- Testing
- Bare Metal Stent, Drug Eluting Stent
- Where
- 2 sites in Argentina
- Volunteers
- 300 people
- Sponsor
- Centro de estudios en Cardiologia Intervencionista
Coronary Artery Disease
Evaluation of a Thin Strut Metallic Stent: the Elixir DynamX Clinical Study
The DynamX (Bioadaptor) study is a prospective, consecutive enrollment study designed to enroll up to 50 patients requiring treatment of a single, de novo lesion ≤ 24 mm in length located in a vessel ≥ 2.5 mm and ≤ 3.5 mm in…
- Trial name
- NCT03429894
- Testing
- Percutaneous Coronary Intervention
- Where
- 2 sites in Belgium, Italy
- Volunteers
- 50 people
- Sponsor
- Elixir Medical Corporation
Carotid Stenosis
Platelet Inhibition and Transcranial Doppler (TCD)-Detected Microemboli During and After Carotid Artery Stenting (CAS) in Asymptomatic Patients Prior to Cardiac Surgery
As with coronary artery stenting, activation and embolisation of platelets occurs with carotid artery stenting (CAS). Based on promising data on the use of clopidogrel plus aspirin in coronary stenting this dual antiplatelet…
- Trial name
- IMPACT (NCT01146301)
- Testing
- Clopidogrel
- Where
- Netherlands
- Sponsor
- R&D Cardiologie
Coronary Stenosis, Coronary Artery Disease
IonMAN II Trial- Early Feasibility Study of the IoNIR Ridaforolimus-Eluting Coronary Stent System
This is a prospective, multi-center, single-arm, open-label, early feasibility study to provide preliminary evidence for the safety and efficacy of the novel IoNIR stent system
- Trial name
- NCT06071702
- Testing
- IoNIR Ridaforolimus-Eluting Coronary Stent System
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Medinol Ltd.
Coronary Artery Disease
Safety and Effectiveness of the Orsiro Mission 48-mm Sirolimus Eluting Coronary Stent System in Subjects With Coronary Artery Lesions
The purpose of the study is to assess the safety and efficacy of the Orsiro® Mission 48- mm Sirolimus-Eluting Coronary Stent System in the treatment of subjects with atherosclerotic lesion(s) >36 mm and ≤ 44 mm in length (by…
- Trial name
- BIOFLOW-48 (NCT06779630)
- Testing
- Orsiro Mission 48-mm Sirolimus-Eluting Coronary Stent System
- Where
- 23 sites in United States, Austria and 4 more
- Volunteers
- 150 people
- Sponsor
- Teleflex
Heart Diseases
Developing and Testing a Personalized Evidence-based Shared Decision-making Tool for Stent Selection
The goal of this study is to gather input from patients who have undergone PCI, their family and/or caregivers, and clinicians to develop a patient decision aid.
- Trial name
- DECIDE-PCI (NCT02046902)
- Where
- 2 sites in United States
- Volunteers
- 586 people, healthy volunteers welcome
- Sponsor
- University of Missouri, Kansas City
Coronary Stenosis, Coronary Disease
IRIS-Firehawk® Cohort in the IRIS-DES Registry
The objective of this study is to evaluate effectiveness and safety of Firehawk® stent in the "real world" daily practice as compared with other drug-eluting stents.
- Trial name
- IRIS Firehawk (NCT03380286)
- Testing
- Firehawk
- Where
- South Korea
- Sponsor
- Duk-Woo Park, MD
Diabetes Mellitus, Coronary Artery Disease
Randomized Trial Comparing Two Sirolimus-Eluting Stents in Diabetes Mellitus
Randomized, controlled, blind, single-center and non-inferiority clinical trial to compare the target lesion failure (TLF) at 12 months in patients with diabetes mellitus who underwent percutaneous coronary intervention with an…
- Conditions
- Diabetes Mellitus, Coronary Artery Disease, Acute Coronary Syndrome
- Trial name
- INC-DM (NCT04660240)
- Testing
- Abluminus Sirolimus Eluting Stent System (ASES), Orsiro Sirolimus Eluting Coronary Stent System (OSES)
- Where
- Mexico
- Volunteers
- 860 people
- Sponsor
- Instituto Nacional de Cardiologia Ignacio Chavez