Clinical trials: Coronary Stent Restenosis
Acute Myocardial Infarction, Restenoses, Coronary
Abbott Vascular Medical Device Registry
The AV-MDR is a prospective, non-randomized, open-label, multi-center registry. The purpose of the AV-MDR study is to proactively collect and evaluate clinical data on the usage of the devices in scope within their intended use…
- Conditions
- Acute Myocardial Infarction, Restenoses, Coronary, Coronary Artery Lesions, Venous Embolism
- Trial name
- AV-MDR (NCT04573660)
- Testing
- Coronary and peripheral stents, Pacing catheters, Vascular plugs
- Where
- 37 sites in United States, Australia and 12 more
- Volunteers
- 3,784 people
- Sponsor
- Abbott Medical Devices
Angina Pectoris, Acute Coronary Syndrome
Integrated Distance Management Strategy for Patients With Cardiovascular Diseases in the Context of COVID-19
Management of known patients with cardiovascular disease (in particular the whole spectrum of atherosclerotic ischaemic coronary artery disease, essential hypertension under treatment, and also patients with chronic heart failure…
- Conditions
- Angina Pectoris, Acute Coronary Syndrome, Coronary Syndrome, Coronary Artery Disease
- Trial name
- eCardioCovid19 (NCT04325867)
- Testing
- Tele-medicine platform
- Where
- 2 sites in Romania
- Volunteers
- 200 people
- Sponsor
- Professor Adrian Covic
Coronary Artery Disease
Virtue® SAB in the Treatment of Coronary ISR Trial
A prospective, multi-center, single-blind, randomized (1:1), non-inferiority study comparing clinical outcomes of the Virtue® Sirolimus AngioInfusion™ Balloon (SAB) to the AGENT™ Paclitaxel Drug-Coated Balloon (DCB) in the…
- Trial name
- NCT07045194
- Testing
- Virtue Sirolimus AngioInfusion Balloon, AGENT™ Paclitaxel Drug-Coated Balloon
- Where
- 22 sites in United States
- Volunteers
- 740 people
- Sponsor
- Orchestra BioMed, Inc
CHD - Coronary Heart Disease, Percutaneous Coronary Intervention
Optical Coherence Tomography Guided Percutaneous Coronary Intervention for Drug-eluting In-stent Restenosis
This study is a prospective, registry trial aimed to compare the clinical and angiographic outcomes of OCT-guided and angiography-guided PCI in patients with coronary DES-ISR.
- Conditions
- CHD - Coronary Heart Disease, Percutaneous Coronary Intervention, In-stent Restenosis
- Trial name
- NCT03809754
- Testing
- Percutaneous Coronary Intervention under OCT, Percutaneous Coronary Intervention under Angiography
- Where
- China
- Volunteers
- 240 people
- Sponsor
- Chinese PLA General Hospital
Coronary In-stent Restenosis
Restenosis Intrastent: Bioresorbable Vascular Scaffolds Treatment With Scoring Balloon Pre-dilatation (RIBS VI Scoring)
Treatment of patients with in-stent restenosis (ISR) remains a challenge. This study will assess the efficacy of Bioresorbable Vascular Scaffolds (BVS) (Abbott Vascular) in the treatment of patients suffering from ISR after…
- Trial name
- NCT03069066
- Testing
- Bioresorbable vascular scaffold. Absorb GT1 (Abbott)
- Where
- 10 sites in Spain
- Volunteers
- 100 people
- Sponsor
- Spanish Society of Cardiology
Coronary Artery Disease, Calcified Coronary Artery Disease
Coronary Laser in Undilatable or Uncrossable Lesions
This will be an investigator-initiated, multicentre, single-arm, open-label, prospective observational study. Patients with indication for PCI and undilatable (non-compliant balloon dilatation <80% at burst pressure) or…
- Conditions
- Coronary Artery Disease, Calcified Coronary Artery Disease, In Stent Restenosis, Chronic Total Occlusion (CTO)
- Trial name
- LUDICO (NCT07206082)
- Testing
- Laser atherectomy
- Where
- Spain
- Volunteers
- 230 people
- Sponsor
- Hospital Universitario La Paz
Acute Coronary Syndrome, Angina Pectoris
DUrable Polymer-based STent CHallenge of Promus Element Versus ReSolute Integrity in an All Comers Population
The introduction of drug-eluting stents (DES) in the treatment of coronary artery disease has led to a significant reduction in morbidity but there are further demands on DES performance.
- Conditions
- Acute Coronary Syndrome, Angina Pectoris, Angina, Unstable, Myocardial Infarction
- Trial name
- DUTCH PEERS (NCT01331707)
- Testing
- Resolute Integrity (Zotarolimus-eluting stent), Promus Element (Everolimus-eluting stent)
- Where
- 4 sites in Netherlands
- Volunteers
- 1,811 people
- Sponsor
- Foundation of Cardiovascular Research and Education Enschede
Vessel Restenosis
Dexamethasone-Eluting Stent in Acute Coronary Syndrome to Prevent Restenosis
The major obstacle of the long- termed success of percutaneous coronary intervention (PCI) is the restenosis. Restenosis results from complex pathophysiological response of the vascular tissue to the balloon injury.
- Trial name
- NCT00190099
- Testing
- Dexamethasone-Eluting Stent
- Volunteers
- 40 people
- Sponsor
- Far Eastern Memorial Hospital
Coronary Artery Disease, In-stent Restenosis
The Effect of Sleep Quality on Coronary Artery Disease and In Stent Restenosis
This is a cross-sectional and follow-up study. We analysis the relationship of sleep quality on coronary artery disease(CAD) and in stent restenosis(ISR).
- Trial name
- NCT03874481
- Testing
- Observation
- Where
- China
- Volunteers
- 958 people, healthy volunteers welcome
- Sponsor
- China National Center for Cardiovascular Diseases
Coronary Restenosis, Coronary Stent Occlusion
Restenosis in Coronary Stents And Cutaneous HEaLing
Case control study of patients with and without restenosis to demonstrate the link between in-stent restenosis and an excessive skin healing.
- Conditions
- Coronary Restenosis, Coronary Stent Occlusion, Skin Scarring, Keloid
- Trial name
- RACHEL (NCT04915391)
- Testing
- Skin biopsy and blood sample for inflammation markers, RNA and proteins
- Where
- Spain
- Volunteers
- 80 people
- Sponsor
- Fundación para la Investigación Biosanitaria del Principado de Asturias
In-stent Coronary Artery Restenosis, Coronary Artery Restenosis
Resveratrol Excipient Paclitaxel Coated Balloon for Coronary Treatment
The objective of this study is to establish reasonable assurance of safety and effectiveness to support an FDA premarket approval (PMA) application for the SeQuent® Please ReX™ Drug Coated PTCA Balloon Catheter as indicated.
- Conditions
- In-stent Coronary Artery Restenosis, Coronary Artery Restenosis, In-stent Restenosis
- Trial name
- RESPECT-ISR (NCT05093244)
- Testing
- SeQuent Please ReX, Plain old balloon angioplasty (POBA)
- Sponsor
- B. Braun Medical Inc.
Coronary Artery Disease
Stenting With or Without Coating Compared With Angioplasty in Non-benestent Disease
The purpose of this study is to evaluate the clinical and angiographic outcome of implantation of stents eluting or not eluting Sirolimus in patients with complex coronary artery lesions suitable for percutaneous coronary…
- Trial name
- NCT00192881
- Testing
- Bx Sonic & Cypher stent from Cordis
- Where
- Denmark
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Coronary Artery Disease, Angina Pectoris
The Real-World Endeavor Resolute Versus XIENCE V Drug-Eluting Stent Study in Twente
The TWENTE Study is a single center prospective single-blinded randomized study. Randomization will involve the type of Drug-Eluting Stent (DES) used in study population.
- Conditions
- Coronary Artery Disease, Angina Pectoris, Unstable Angina Pectoris, Coronary Stenosis
- Trial name
- TWENTE (NCT01066650)
- Testing
- Endeavor Resolute (Biolinx-based Zotarolimus-eluting stent), Xience V (Everolimus-eluting stent)
- Where
- Netherlands
- Volunteers
- 1,391 people
- Sponsor
- Foundation of Cardiovascular Research and Education Enschede
Coronary Artery Disease, Coronary Restenosis
Clinical Performance of the Pantera Lux Balloon Versus the Orsiro Stent in Patients With In-stent Restenosis.
To determine in a randomized controlled trial (RCT) whether percutaneous coronary intervention - in patients with in-stent restenosis in either bare metal stents or drug eluting stents - with the Pantera Lux balloon is…
- Trial name
- BIOLUX-RCT (NCT01651390)
- Testing
- Percutaneous coronary intervention
- Where
- 14 sites in Germany, Latvia
- Volunteers
- 231 people
- Sponsor
- Biotronik AG
Coronary Artery Disease
Drug Elution and Distal Protection During Percutaneous Coronary Intervention in ST Elevation Myocardial Infarction
The purpose of this study is to evaluate the clinical, echocardiographic and angiographic outcome of distal protection in the infarct related coronary artery and implantation of drug eluting versus bare metal stents in patients…
- Trial name
- NCT00192868
- Testing
- Distal protection and drug eluting stent
- Where
- Denmark
- Volunteers
- 600 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet