Clinical trials: Coronavirus Disease 2019
Covid19, Vitamin D
Efficacy of Vitamin D Supplementation to Prevent the Risk of Acquiring COVID-19 in Healthcare Workers
In a blinded randomized clinical trial, which will include health workers (doctors, residents, nurses, stretcher-bearers, technicians, hygiene and cleaning) who are members of the health teams that care for patients with…
- Trial name
- COVID-19 (NCT04535791)
- Testing
- Cholecalciferol
- Where
- Mexico
- Volunteers
- 321 people, healthy volunteers welcome
- Sponsor
- Coordinación de Investigación en Salud, Mexico
COVID19
ABC Science Collaborative Registry Study
The ABC Registry is associated with Pro00107943 and provides a resource for collecting information on members of school communities both regionally in North and South Carolina, as well as nationally in the United States (U.S.)…
- Trial name
- NCT04781218
- Volunteers
- healthy volunteers welcome
- Sponsor
- Duke University
Long COVID, Post COVID-19 Condition
Investigating the Effectiveness of Vimida
This randomized controlled trial (RCT) with 160 patients suffering from fatigue after COVID-19 infection aims to investigate the effectiveness of the unguided digital therapeutic vimida for reducing post-COVID-19 fatigue.
- Trial name
- InvidiCO (NCT06251518)
- Testing
- vimida
- Where
- Germany
- Volunteers
- 160 people
- Sponsor
- Gaia AG
Lung Diseases, Cardiac Disease
Sequelae of Sars-CoV-2 Infections
By the end of 2019 a new coronavirus, named SARS-CoV-2, was discovered in patients with pneumonia in Wuhan, China. In the following weeks and months the virus spread globally, having a tremendous impact on global health and…
- Conditions
- Lung Diseases, Cardiac Disease, Inflammatory Reaction
- Trial name
- NCT04442789
- Where
- Germany
- Volunteers
- 120 people
- Sponsor
- University of Giessen
Telemedicine
Covid-19 Predictors: Safety of Gynecological Oncology Patients Undergoing Systemic Cancer Therapy
We designed a monocenter prospective cohort study using PROM via app and remote monitoring via pho-toplethysmography (PPG). The application of these technologies enables an early detection of infections and therefore initiation…
- Trial name
- CO-SI-ONKO (NCT05043220)
- Testing
- PPG and PROM
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- Technical University of Munich
Severe COVID-19 Pneumonia
ANTIcoagulation in Severe COVID-19 Patients
Coronavirus disease 2019 (COVID-19), a viral respiratory illness caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), may predispose patients to thrombotic disease due to a state of profound inflammation…
- Trial name
- ANTICOVID (NCT04808882)
- Testing
- Tinzaparin, Low dose prophylactic anticoagulation, Tinzaparin, High dose prophylactic anticoagulation, Tinzaparin,Therapeutic anticoagulation
- Where
- France
- Volunteers
- 353 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Covid19, Bronchoscopy
Narrow Band Imaging Bronchoscopy During SARS-CoV2 Infection
Vascular modifications have been described during SARS-CoV2 infection, especially a dilatation of the bronchial arteries. Within the airway wall, small branches of the bronchial arteries cross the muscle layer to develop a…
- Conditions
- Covid19, Bronchoscopy, Narrow-band Imaging
- Trial name
- SARS-CoV2-NBI (NCT04884061)
- Testing
- NBI images and/or videos
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Allogenic Hematopoietic Cell Transplant, CAR-T Therapy
COVID-19 Vaccine in Patients After Allogeneic HCT, CAR-T Therapy and With Primary Immune Deficiency
The corona pandemic is a continuing global challenge due to Corona Virus 2019 (COVID-19). The purpose of the study is to confirm the accepted hypothesis from the recommendations of The European Society for Blood and Marrow…
- Conditions
- Allogenic Hematopoietic Cell Transplant, CAR-T Therapy, Primary Immunodeficiency
- Trial name
- NCT04724642
- Where
- Israel
- Volunteers
- 110 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
SARS-CoV-2 Infection
SARS-CoV-2-Neutralizing Monoclonal COVID-19 Antibody DZIF-10c by Inhalation
This is the first-in-human phase 1/2a trial of the inhaled administration of the SARS-CoV-2-neutralizing monoclonal antibody DZIF-10c in healthy volunteers and SARS-CoV-2-infected individuals.
- Trial name
- NCT04631705
- Testing
- DZIF-10c
- Where
- 6 sites in Germany
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Cologne
Critical Illness, COVID-19
Modafinil for Wakefulness in the Critical Care Units
It has been well documented that patients in the intensive care unit (ICU) are susceptible to developing neurocognitive and musculoskeletal complications because of various factors, including the nature of the critical illness…
- Conditions
- Critical Illness, COVID-19, Cognitive Dysfunction
- Trial name
- NCT04751227
- Testing
- Modafinil
- Where
- Saudi Arabia
- Volunteers
- 8 people
- Sponsor
- King Faisal Specialist Hospital & Research Center
COVID-19, SARS-CoV-2 Infection
Clinical Characteristics and Outcomes of Pediatric COVID-19
Rationale: The clinical manifestations of SARS-CoV-2 infection in children are poorly characterized. Preliminary findings indicate that they may be atypical.
- Conditions
- COVID-19, SARS-CoV-2 Infection, Pediatric ALL, Pneumonia, Viral
- Trial name
- PERN-COVID-19 (NCT04330261)
- Testing
- Exposure (not intervention) - SARS-CoV-2 infection
- Where
- Canada
- Volunteers
- 10,610 people
- Sponsor
- University of Calgary
Covid19
Efficacy and Safety of Ovotransferrin in COVID-19 Patients
Chicken egg consists of three main components, egg white (56%), yolk (33%) and shell (11%). The key component of egg white is 88 percent water and 12 percent solids, of which over 90 percent are protein.
- Trial name
- NCT04643054
- Testing
- Ovotransferrin
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Azienda Ospedaliera Universitaria Policlinico Paolo Giaccone Palermo
Covid19
Long-term Effects of COVID-19: a Comparative Cohort Study
This study is a longitudinal cohort study which investigates the effect of COVID-19 in ambulatory care. This study aims to assess the effect of COVID-19 beyond the acute phase, i.e.
- Trial name
- CoCo (NCT05002205)
- Testing
- Questionnaires, spirometry, ECG
- Volunteers
- 180 people
- Sponsor
- KU Leuven
Covid19
Rehabilitation After Covid19-Clinical Results and Predictive Factors
The aim of the study is to gain insight into the rehabilitation process and predictive factors for the outcome after rehabilitation in three patient groups: 1. SARS-CoV-2-positive patients in the isolation ward 2.
- Trial name
- NCT04896905
- Testing
- Rehabilitation
- Where
- Switzerland
- Volunteers
- 101 people
- Sponsor
- Klinik Valens
COVID-19, Infection
Effect of COVID-19 Infection on Obstertric Complications and Maternal Outcomes
This study aimed to evaluate the effect of COVID-19 infection on obstetric complications and maternal outcomes.
- Conditions
- COVID-19, Infection, Obstetric Complication, Maternal Outcomes
- Trial name
- NCT06557694
- Testing
- Data collection
- Where
- Egypt
- Volunteers
- 260 people
- Sponsor
- Tanta University
COVID, ARDS
Intensive Care Therapy of Covid-19 Disease in Germany
Multi-center retrospective and prospective observational study of Covid-19 patients with severe or critical illness treated on a German ICU
- Trial name
- NCT04455451
- Where
- 27 sites in Germany
- Volunteers
- 2,054 people
- Sponsor
- University Hospital Tuebingen
Long COVID, Multiple Chronic Conditions
The Impact of Long COVID on People Living With Pre-existing LTC
The goal of this observational study is to learn about the impact of long COVID on people who have multiple (two or more) pre-existing long-term conditions (such as diabetes and asthma).
- Trial name
- NCT06223997
- Volunteers
- 20 people
- Sponsor
- University of Leicester
Covid19, Old Age; Debility
Mortality Due to COVID-19 in the COVID-AGEBRU Study
The COVID-Age Brugmann study aims to identify the clinical predictors of mortality risk in older patients admitted to an acute care unit due to COVID-19
- Conditions
- Covid19, Old Age; Debility, Morbidity, Multiple
- Trial name
- COVID-AGEBRU (NCT04756479)
- Where
- Belgium
- Volunteers
- 160 people
- Sponsor
- Brugmann University Hospital
COVID-19
Retrospective Study for Identificatiopn of a Link Between Doxycycline and COVID-19 Treatment
A new coronavirus, the third documented animal-to-human passage, emerged in Wuhan , China in the last quarter of 2019. Acne patients on doxycycline escaped seasonal viruses, showing the interest of this antibiotic as a possible…
- Trial name
- DOXY-COVID (NCT05445479)
- Testing
- Doxycycline
- Sponsor
- Nantes University Hospital
COVID-19
Recombinant Human Angiotensin-converting Enzyme 2 (rhACE2) as a Treatment for Patients With COVID-19
This is an open label, randomized, controlled, pilot clinical study in patients with COVID-19, to obtain preliminary biologic, physiologic, and clinical data in patients with COVID-19 treated with rhACE2 or control patients, to…
- Trial name
- NCT04287686
- Testing
- Recombinant human angiotensin-converting enzyme 2 (rhACE2)
- Where
- China
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
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