Clinical trials: Coronavirus Infection (COVID-19)
Covid19, Acute Cor Pulmonale
Cardiac Performance in Mechanically Ventilated COVID-19 Patients
Although COVID-19 affects primarily the respiratory system, several studies have shown evidence of cardiovascular alterations. Increased troponin levels were observed in a significant proportion of patients and this alteration…
- Conditions
- Covid19, Acute Cor Pulmonale, Cardiac Failure
- Trial name
- NCT04628195
- Where
- Chile
- Volunteers
- 100 people
- Sponsor
- Pontificia Universidad Catolica de Chile
Health Behavior
Health Behavior Change During COVID-19 Pandemic
This study aims at investigating handwashing behavior during COVID-19 pandemic. It was hypothesized that social-cognitive and emotional predictors as well as COVID-19 morbidity and mortality rates within the country would be…
- Trial name
- NCT04367337
- Testing
- No intervention
- Where
- 14 sites in Australia, Canada and 12 more
- Volunteers
- 6,079 people, healthy volunteers welcome
- Sponsor
- University of Social Sciences and Humanities, Warsaw
SARS-CoV-2 Infection, COVID-19
A Study Looking at the Effectiveness, Immune Response, and Safety of a COVID-19 Vaccine in Adults in the United Kingdom
This is a study to evaluate the efficacy, immune response, and safety of a coronavirus disease 2019 (COVID-19) vaccine called SARS-CoV-2 rS with Matrix-M1 adjuvant in adults aged 18-84 years in the United Kingdom.
- Trial name
- NCT04583995
- Testing
- SARS-CoV-2 rS/Matrix M1-Adjuvant, Licensed seasonal influenza vaccine
- Where
- 33 sites in United Kingdom
- Volunteers
- 15,185 people, healthy volunteers welcome
- Sponsor
- Novavax
COVID-19
Povidone Iodine Mouthwash, Gargle, and Nasal Spray to Reduce Naso- Pharyngeal Viral Load in Patients With COVID-19
The SARS-CoV-2 coronavirus pandemic is responsible for more than 180,000 deaths worldwide and 20,000 deaths in France. To date, no treatment or vaccine has been successful.
- Trial name
- KILLER (NCT04371965)
- Testing
- Povidone-Iodine
- Where
- France
- Volunteers
- 24 people
- Sponsor
- Poitiers University Hospital
COVID-19
Safety, Tolerability, and Pharmacokinetics Study of Human Monoclonal Antibody BRII-198
This is a phase 1 study in which healthy adult volunteers will receive BRII-198 or placebo and will be assessed for safety, tolerability, and pharmacokinetics.
- Trial name
- NCT04479644
- Testing
- BRII-198
- Where
- China
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Brii Biosciences Limited
Stress, Anxiety
Post-Pandemic Perception of Public Space in Singapore
In this study it is aimed to investigate the difference between the brain response to different urban environments in Singapore before and after the COVID-19 pandemic.
- Trial name
- NCT04394039
- Testing
- Public space exposure
- Where
- Singapore
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Advanced Malignant Solid Neoplasm, COVID-19 Infection
Distress Associated with Coronavirus Disease 2019 and Telehealth on Supportive Care Patients with Advanced Cancer
This study assesses the level of distress felt by cancer patients due to the coronavirus disease 2019 (COVID-19) pandemic. Researchers also want to learn if patients prefer to receive supportive care (palliative care) in person…
- Conditions
- Advanced Malignant Solid Neoplasm, COVID-19 Infection, Hematopoietic and Lymphoid Cell Neoplasm, Locally Advanced Malignant Solid Neoplasm
- Trial name
- NCT05058339
- Testing
- Survey Administration
- Where
- United States
- Volunteers
- 223 people
- Sponsor
- M.D. Anderson Cancer Center
Stress, Anxiety
Emotional Freedom Technique (EFT) Effect on Nurses
Background: Infectious disease outbreaks have a psychological effect on the general population, and especially on health workers.
- Conditions
- Stress, Anxiety, Burnout, Caregiver
- Trial name
- NCT04393077
- Testing
- Emotional Freedom Technique
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Istanbul Saglik Bilimleri University
COVID-19-Associated Encephalitis, Long COVID
Longterm Influence of Pediatric Long COVID Syndrome
We enroll pediatric patients who were diagnosed COVID-19 for main observation target. We will perform brain MRI and neuropsychiatric evaluation 4-6 months after COVID-19 diagnosed.
- Trial name
- NCT05566392
- Testing
- Brain MRI
- Where
- Taiwan
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
COVID-19
The Measurement of Chemicals in Exhaled Breath Can Identify If a Person is Infected with COVID-19
The type and number of chemicals in exhaled breath are different in people with infection as compared to those without infection. In this study, the breath of people with and without COVID infection will be measured.
- Trial name
- NCT06571136
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- N5 Sensors
COVID-19, Testosterone Deficiency
SARS-CoV-2, TESTOSTERONE AND MALE FRAGILITY
The hormonal environment (steroid, primarily) could have a very relevant pathophysiological role in association with SARS-CoV-2.
- Conditions
- COVID-19, Testosterone Deficiency, Infertility, Male
- Trial name
- PROTEGGIMI (NCT06177002)
- Testing
- Collection of biological data
- Where
- Italy
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- IRCCS San Raffaele
COVID-19
Colchicine in COVID-19: a Pilot Study
This is an interventional, pilot, multicenter, randomized, open-label, phase 2 study, enrolling patients with COVID-19 disease. One-month rate of entering the critical stage (either a.
- Trial name
- COLVID-19 (NCT04375202)
- Testing
- Colchicine 1 MG Oral Tablet
- Where
- 2 sites in Italy
- Volunteers
- 227 people
- Sponsor
- University Of Perugia
Coronavirus Disease 2019 Infectious Disease (COVID-19 Infection)
Amotosalen-Ultraviolet A Pathogen-Inactivated Convalescent Plasma in Addition to Best Supportive Care and Antiviral Therapy on Clinical Deterioration in Adults Presenting With Moderate to Severe COVID-19
This project investigates individual treatments using convalescent severe acute respiratory Syndrome Coronavirus 2 (SARS-CoV-2) plasma in SARS-CoV-2 infected patients at risk for disease progression.
- Trial name
- NCT04389944
- Testing
- convalescent plasma application to SARS-CoV-2 infected patients
- Where
- Switzerland
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Venous Thromboembolism, Covid19
COVID-19 and Venous Thromboembolism Risk
Coronavirus disease 2019 (Covid-19) is now a leading cause of death among U.S. adults. In addition to profound respiratory and multi-organ failure, hypercoagulable states and venous thromboembolism (VTE) have been increasingly…
- Trial name
- NCT04569344
- Testing
- Laboratory test positive for SARS-CoV-2 virus
- Where
- 2 sites in United States
- Volunteers
- 398,530 people
- Sponsor
- University of California, San Francisco
Covid19, CBD
Synthetic CBD as a Therapy for COVID-19
The study aim to test proof of concept of CBD treatment for efficacy and safety in patients suffering with mild COVID-19 infection. The CBD will be delivered via oil droplets not containing THC, compared to placebo.
- Trial name
- NCT04686539
- Testing
- CBD
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- Sheba Medical Center
Multiple Sclerosis, COVID-19
The United Kingdom Multiple Sclerosis Register Covid-19 Substudy
The aim of the study is to understand the impact of COVID-19 on People with Multiple Sclerosis in the United Kingdom.
- Trial name
- UKMSRCV19 (NCT04354519)
- Where
- United Kingdom
- Volunteers
- 3,000 people
- Sponsor
- Swansea University
COVID-19
Retrospective Cohort Study of the Physiotherapy in Critically Ill Covid Patients
Retrospective cohort study that will include patients from the ICU of the Hospital de la Santa Creu i Sant Pau in Barcelona during the period between March 11 and May 13, 2020.
- Trial name
- NCT06042881
- Where
- Spain
- Volunteers
- 189 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
COVID-19
Study to Evaluate the Safety and Antiviral Activity of Remdesivir (GS-5734™) in Participants With Severe Coronavirus Disease (COVID-19)
The primary objective of this study is to evaluate the efficacy of 2 remdesivir (RDV) regimens with respect to clinical status assessed by a 7-point ordinal scale on Day 14.
- Trial name
- NCT04292899
- Testing
- Remdesivir, Standard of Care
- Where
- 183 sites in United States, China and 13 more
- Volunteers
- 4,891 people
- Sponsor
- Gilead Sciences
Coronavirus Disease 2019 (COVID-19)
Increased Risk of Severe Coronavirus Disease 2019 in Patients With Vitamin D Deficiency
In this prospective observational study we aim to study the association of vitamin D deficiency with adverse clinical outcomes in patients infected with Coronavirus disease 2019
- Trial name
- COVIT-D (NCT04403932)
- Where
- Spain
- Volunteers
- 300 people
- Sponsor
- Hospital San Carlos, Madrid
Covid-19
A Study of COVID-19 Patients Receiving Treatment With Nirmatrelvir; Ritonavir in the Kingdom of Saudi Arabia
The aim of this study is to describe the baseline demographic, clinical characteristics, and Healthcare Resource Use (HCRU) of adult (≥18 years) COVID-19 patients who have been prescribed nirmatrelvir, ritonavir treatment.
- Trial name
- NCT06016556
- Testing
- nirmatrelvir, ritonavir
- Where
- 3 sites in Saudi Arabia
- Volunteers
- 250 people
- Sponsor
- Pfizer
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.