Clinical trials: Corticosteroid Injection
Asthma
Safety and Efficacy Study Adding GSK2190915 to Mid-dose Inhaled Corticosteroid/Long Acting Beta Agonist Combination Treatment for Asthma
The primary objective of this study is to evaluate the efficacy and safety of adding GSK2190915 300mg or placebo tablets administered once daily to fluticasone propionate/salmeterol 250/50mcg inhalation powder administered twice…
- Trial name
- NCT01248975
- Testing
- FP/SAL 250/50mcg BID, GSK2190915 200mg QD (AM), GSK2190915 100mg QD (AM)
- Where
- 19 sites in Bulgaria, Poland and 1 more
- Volunteers
- 145 people
- Sponsor
- GlaxoSmithKline
Baker's Cyst
PRP vs Corticosteroid in Baker's Cyst
This is a Prospective study with Randomized patients into either Ultrasound-guided Platelets-Rich-Plasma injection and Ultrasound guided Corticosteroid Injection, with 3 months and 6 months follow ups after aspiration at our…
- Trial name
- NCT02249377
- Testing
- Platelets-Rich-Plasma, Corticosteroid
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- NYU Langone Health
Chronic Sinusitis, Nasal Polyposis
Safety Evaluation of Repeat Placement of the S8 Sinus Implant in Chronic Sinusitis Patients With Nasal Polyps (ENCORE)
The ENCORE Study is designed to evaluate the repeat administration of the S8 Sinus Implant in chronic sinusitis (CS) patients with recurrent nasal polyps.
- Trial name
- NCT03358329
- Testing
- S8 Sinus Implant
- Where
- 9 sites in United States
- Volunteers
- 50 people
- Sponsor
- Intersect ENT
Wheezing
PREcision Medicine Directed Corticosteroids In Children With preSchool Wheeze
Young children frequently attend the emergency department (ED) with wheeze which is usually triggered by a virus infection, such as the common cold.
- Trial name
- PRECISE (NCT06580600)
- Testing
- Point of care respiratory virus testing
- Where
- United Kingdom
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Queen's University, Belfast
Influenza
Adaptive RCT of Corticosteroids for Severe Influenza Pneumonia in Adults
Severe community-acquired pneumonia caused by influenza virus (hereafter referred to as severe influenza pneumonia) is a major etiology of community-acquired pneumonia leading to acute respiratory failure and ICU admission.
- Trial name
- CAPSTONE-IFV (NCT07351500)
- Testing
- Saline (0.9%, sterile, for infusion), low dose Methylprednisolone, Moderate dose Methylprednisolone
- Volunteers
- 496 people
- Sponsor
- Qingyuan Zhan
Ventilator Associated Pneumonia
Low Versus High Corticosteroid Use in Ventilator Associated Pneumonia
patients who had >3 on Murray score and >6 on CPIS allocated randomly in two groups 120 patients in each. Group A received 30 mg/kg methyl-prednisolone slowly intravenous in 250 mL normal saline every 8 hours for only 48 hours…
- Trial name
- NCT04467892
- Testing
- methylprednisolone, Methyl Prednisolonate, ventilators
- Where
- Saudi Arabia
- Volunteers
- 240 people
- Sponsor
- King Abdul Aziz Specialist Hospital
Stroke, Shoulder Pain
Hemiplegic Shoulder Pain Management Using Shoulder pRF and Corticosteroid Injection
Introduction: hemiplegic shoulder pain (HSP) in a common post-stroke condition, that can lead to poor motor and functional recovery and lower quality of life.
- Trial name
- NCT05563571
- Testing
- Methylprednisolon, Lidocaine, Pulsed radiofrequency, Lidocaine
- Where
- Finland
- Volunteers
- 20 people
- Sponsor
- Satasairaala
Shoulder Impingement
Standardized and Modified Corticosteroid Subacromial Injection for Shoulder Impingement Syndrome
Subacromial injection is a useful procedure to counteract shoulder impingement syndrome. With the aid of high-resolution ultrasound, the needle can be introduced precisely into the subacromial/subdeltoid bursa located between the…
- Trial name
- SMCSINJ (NCT03148353)
- Testing
- Subacromial injection
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- National Taiwan University Hospital
Asthma
A Safety Extension Study to Evaluate the Safety and Tolerability of Benralizumab (MEDI-563) in Asthmatic Adults and Adolescents on Inhaled Corticosteroid Plus LABA
The purpose of this study is to characterize the safety profile of benralizumab administration in asthma patients who have completed one of the three predecessor studies: D3250C00017, D3250C00018 or D3250C00020.
- Trial name
- BORA (NCT02258542)
- Testing
- Benralizumab
- Where
- 429 sites in United States, Argentina and 22 more
- Volunteers
- 2,133 people
- Sponsor
- AstraZeneca
Graft vs Host Disease
Evaluation of Antifungal Prophylaxis on Graft-versus-host Disease (GVHD) Patients
Antifungal prophylaxis should be used in patients being treated with glucocorticoids for graft-versus-host disease (GVHD) following allogeneic hematopoietic stem-cell transplantation (HSCT).
- Trial name
- ITRAG (NCT01282879)
- Testing
- Itraconazole
- Where
- 9 sites in South Korea
- Volunteers
- 36 people
- Sponsor
- Samsung Medical Center
Dysphagia, Pain
Dexamethasone in Reducing Oral Pain and Dry Mouth After Surgery in Patients With Oropharyngeal Cancer
This randomized pilot clinical trial studies dexamethasone in reducing oral pain and dry mouth after surgery in patients with oropharyngeal cancer. Dexamethasone may help lower pain and dry mouth caused by surgery.
- Conditions
- Dysphagia, Pain, Stage I Oropharyngeal Squamous Cell Carcinoma, Stage II Oropharyngeal Squamous Cell Carcinoma
- Trial name
- NCT01748942
- Testing
- Dexamethasone, Quality-of-Life Assessment, Questionnaire Administration
- Where
- United States
- Volunteers
- 76 people
- Sponsor
- OHSU Knight Cancer Institute
Chronic Obstructive Pulmonary Disease
Safety, Tolerability and Pharmacokinetics of Multiple Ascending Doses of AZD8871 in Healthy Subjects
AZD8871 is a new chemical entity possessing long-acting effect in a single molecule which presents a novel treatment approach to chronic obstructive pulmonary disease [COPD] and potentially also asthma (in combination with an…
- Trial name
- NCT02814656
- Testing
- AZD8871
- Where
- United Kingdom
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Adhesive Capsulitis, Frozen Shoulder
Corticosteroids and / or Arthrographic Distention in the Treatment of Adhesive Capsulitis
Arthrographic distention of the shoulder joint is an increasingly popular treatment option in the management of patients with frozen shoulder.
- Trial name
- CADAC (NCT01983527)
- Testing
- Arthrographic distention, Intra-articular corticosteroid Depo Medrol
- Where
- Belgium
- Volunteers
- 132 people
- Sponsor
- Imelda Hospital, Bonheiden
Inflammation Corneal, Pain, Postoperative
OCS-01 in Treating Inflammation and Pain in Post-cataract Patients
The DX-216 trial is a randomized, double-masked, placebo (vehicle)-controlled study evaluating the efficacy and safety of two doses of OCS-01 compared to vehicle in the treatment of inflammation and pain following cataract…
- Trial name
- SKYGGN (NCT04130802)
- Testing
- OCS-01 - Dexamethasone Cyclodextrin Nanoparticle Ophthalmic Suspension 1.5% mg/mL
- Where
- 4 sites in United States
- Volunteers
- 153 people
- Sponsor
- Oculis
Chronic Rhinosinusitis
Bactorinol® Nasal Spray With Reduced-Dose Mometasone in Adults With Chronic Rhinosinusitis
Chronic rhinosinusitis (CRS) is a persistent inflammatory disease of the nose and sinuses, defined by the presence of symptoms for at least 12 weeks.
- Trial name
- NCT07800273
- Testing
- Bactorinol® (manufacturer: PharmExtracta S.p.A.), Mometasone Furoate Nasal Spray
- Where
- Italy
- Volunteers
- 78 people
- Sponsor
- Liaquat University of Medical & Health Sciences
Liver Transplantation
Enteric Coated Myfortic for Liver Transplant Recipients
The purpose of this study is to replace the mycophenolate mofetil (Cellcept) which is our usual therapy after liver transplantation with sodium mycophenolic acid (Myfortic®) and to find out the effect this change may have on the…
- Trial name
- NCT00167492
- Testing
- Myfortic
- Where
- United States
- Sponsor
- The University of Texas Health Science Center, Houston
Oral Lichen Planus
Clinical and Immunohistochemical Effect of Topical Pimecrolimus in Treatment of Oral Lichen Planus
Oral lichen planus (OLP) is a chronic disease characterized by periods of remission and relapse. Therapeutic objectives for OLP should be to quickly reduce disease symptoms by targeting pathophysiological pathways, and to provide…
- Trial name
- NCT02443311
- Testing
- Pimecrolimus 1% cream, Betamethasone 17-valerate 0.1% cream
- Volunteers
- 24 people
- Sponsor
- Ain Shams University
Frozen Shoulder, Adhesive Capsulitis
Frozen Shoulder Treatment With Intra-Articular Corticosteroid Injection and Suprascapular Nerve Block
Frozen shoulder remains a challenging disease to treat as pain and loss of range of motion can persist for many months or even years.
- Trial name
- FROSTBLOCK (NCT06229964)
- Testing
- SSNB + IACI
- Where
- Belgium
- Volunteers
- 110 people
- Sponsor
- Universitair Ziekenhuis Brussel
Tooth Impaction | {Tooth} | Dental, Corticosteroid
Comparison of the Effects of Protocols Applied After Surgical Extraction of Impacted Mandibular Third Molars
Following the surgical extraction of the most commonly impacted mandibular third molars, the first group was planned to receive methylprednisolone, the second group hyaluronic acid, the third group ozone therapy, the fourth group…
- Conditions
- Tooth Impaction | {Tooth} | Dental, Corticosteroid, Hyaluronic Acid, Ozone
- Trial name
- NCT06900907
- Testing
- Diode laser, Hyaluronic acid, Ozone
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Batman University
Systemic Lupus Erythematosus, High LDL Cholesterol Level
Efficacy and Adverse Effect of Simvastatin Compare to Rosuvastatin in Systemic Lupus Erythematosus (SLE) Patients With Corticosteroid Therapy and High Low-Density Lipoprotein (LDL) Cholesterol Level
Early statin therapy in SLE patients that have high cholesterol level and other atherosclerosis risk should reduce atherosclerosis and coronary artery events in later course of disease.
- Trial name
- NCT00866229
- Testing
- Rosuvastatin, Simvastatin
- Where
- Thailand
- Volunteers
- 140 people
- Sponsor
- Ramathibodi Hospital