Clinical trials: Cortisol
Premature Infant, Pain
The Effect of Breast Milk Odor on Pain Response and Salivary Cortisol Level in Preterm Infants
The aims of this randomized controlled trial are investigate the effects of breast milk odor on pain response and saliva cortisol level duration heel stick blood sampling in preterm infants.
- Conditions
- Premature Infant, Pain, Breast Milk Odor
- Trial name
- NCT05557435
- Testing
- breast milk odor
- Volunteers
- 64 people
- Sponsor
- Taipei Medical University
Intensive Care Unit
Effect of Music on Patients in Intensive Care Units
The purpose of this study is to investigate the effects of patient-preferred music, relaxation music, and standard care environment on patients in intensive care units.
- Trial name
- MTS2 (NCT00823017)
- Testing
- Patient-preferred music, Relaxation Music, Standard Care Environment
- Where
- United States
- Sponsor
- MetroHealth Medical Center
Addison's Disease
Glucocorticoid Treatment in Addison's Disease
Addison's disease is a rare condition which in most cases is caused by autoimmune destruction of the adrenals, leading to deficiency of cortisol, aldosterone and adrenal androgens.
- Trial name
- NCT01063569
- Testing
- Solu-Cortef (hydrocortisone), Cortef (hydrocortisone)
- Where
- 3 sites in Norway, Sweden
- Volunteers
- 33 people
- Sponsor
- Haukeland University Hospital
Depression
Epinephrine and Cortisol in Depression
This study investigates the effects of two hormones called epinephrine and cortisol on how the brain processes emotional material using functional MRI to measure brain activity.
- Trial name
- NCT04148261
- Testing
- Hydrocortisone Acetate (CORT), Epinephrine Sulfate (EPI)
- Volunteers
- healthy volunteers welcome
- Sponsor
- Stanford University
Adrenal Insufficiency
Mass Spectrometry Based Cutoffs for Cortisol After Stimulation Tests
There are two main stimulation tests used to decide if a patient has cortisol deficiency. It is the "synacthen test", were we stimulate the patient with intramuscular or intravenous synacthen ( ACTH) to see how much cortisol the…
- Trial name
- NCT02818660
- Testing
- Synachten
- Where
- Norway
- Volunteers
- 232 people, healthy volunteers welcome
- Sponsor
- Haukeland University Hospital
Posttraumatic Stress Disorders, Cortisol Diurnal Variation
Cortisol Diurnal Variation and the Risk for Developing Post Traumatic Stress Disorder
The purpose of this study is to examine a possible link between the time of day of exposure to a traumatic event and the risk of developing post-traumatic stress disorder.
- Trial name
- NCT01914861
- Where
- Israel
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Hospitalized Child
Effect of Augmented Reality Books on Cortisol Levels in Hospitalized Pediatric Patients
Hospitalization is a stressful event that might impact in a patient's recovery. Children are more susceptible to suffer acute stress as a result of a hospital stay.
- Trial name
- NCT03537859
- Testing
- Augmented Reality, Non Augmented Reality
- Where
- Peru
- Volunteers
- 29 people
- Sponsor
- Universidad Peruana Cayetano Heredia
Exercise
Effects of HIIT and MICT Training on Cardiorespiratory Fitness, Testosterone/Cortisol Ratio, and Mental Health in Young Adults
This study will use a randomized, double-blind clinical trial to evaluate the effects of eight-week HIIT and MICT exercise programs on cardiorespiratory fitness, the testosterone/cortisol ratio, and mental health in 68 healthy…
- Trial name
- NCT07397702
- Testing
- High-intensity interval training, Moderate-intensity continuous training
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Universidad de Colima
Septic Shock
Hydrocortisone and Fludrocortisone for the Treatment of Septic Shock
The purpose of this study is to evaluate the efficacy and safety of the combination therapy of hydrocortisone and fludrocortisone among adult patients with septic shock.
- Trial name
- NCT07383103
- Testing
- Hydrocortisone plus Fludrocortisone, Standard care
- Where
- China
- Volunteers
- 336 people
- Sponsor
- Northern Jiangsu People's Hospital
Post-Traumatic Stress Disorders
Early Intervention for Post Traumatic Stress Disorder (PTSD)
Over 150,000 soldiers are currently deployed in Iraq as part of Operation Iraqi Freedom (OIF), and 12% of returning OIF veterans have posttraumatic stress disorder (PTSD).
- Trial name
- NCT00641173
- Testing
- paroxetine
- Sponsor
- US Department of Veterans Affairs
Ocular Surface Disease, Glaucoma
Effects of Topical Low Dose Preservative-free Hydrocortisone on Intraocular Pressure
Evaluation of the safety and efficacy of hydrocortisone eye drops in the treatment of OSD (ocular surface disease) patients with and without glaucoma.
- Trial name
- NCT04536129
- Testing
- Hydrocortisone (CORTIVIS ®)
- Where
- Italy
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Molise
Alcohol Use Disorder
Imaging CRF X NOP Interactions in Alcohol Use Disorder
This positron emission tomography imaging study uses [C-11]NOP-1A and hydrocortisone to image stress-modulating proteins in heavy drinking alcohol use disorder (AUD) subjects and healthy controls (HC).
- Trial name
- NCT07612631
- Testing
- Baseline [C-11]NOP-1A PET scan, Hydrocortisone, Post-hydrocortisone [C-11]NOP-1A PET scan
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Rajesh Narendran
Autism Spectrum Disorder, Mental Disorders
Physiological Mechanisms of Therapeutic Horseback Riding Intervention Effects in a Psychiatric Population of ASD Youth
This randomized control trial (RCT) seeks to assess the mechanisms underlying Therapeutic Horseback Riding's (THR) previously observed significant positive effects on ASD youth, particularly those with co-occurring psychiatric…
- Trial name
- NCT04606966
- Testing
- Therapeutic Horseback Riding, Barn Activity, Hybrid
- Where
- 2 sites in United States
- Volunteers
- 236 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Pregnancy and Medically Assisted Reproduction
Antenatal Stress and Infants In MAR
The goal of this observational longitudinal study is to examine the association between prenatal psychological and biological stress and neonatal health outcomes in couples who conceived through medically assisted reproduction.
- Trial name
- SARA (NCT07408453)
- Testing
- Diagnostic procedures
- Where
- Italy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- IRCCS Eugenio Medea
Depression
The Effect of Cortisol Administration on Neural Correlates of Emotion in Depression
There is good evidence to suggest that the pathological version of sadness that people with Major Depression experience could be caused by the failure of the hormone cortisol to properly inhibit sadness-related brain activity in…
- Trial name
- NCT02837432
- Testing
- Hydrocortisone acetate
- Where
- United States
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- Stanford University
Type 1 Diabetes
Glucose Variability in Type 1 Diabetes and Its Effect on Factors That Influence New Vessel Formation
The aim of the study is to see how glycaemic control and glycaemic variability affect levels of HIF, VEGF, erythropoietin and cortisol in Paediatric Type 1 diabetics on insulin pump therapy.
- Trial name
- INDIGO 2 (NCT01429467)
- Testing
- Continuous Glucose Monitor (CGM) and Telemedicine (Enlite Guardian real-time system Medtronic®)
- Where
- United Kingdom
- Volunteers
- 35 people
- Sponsor
- University of Dundee
Acute Coronary Syndrome, Stress Hyperglycemia
Cellular Immunity, Neuroendocrine, and Inflammatory Factors for Clinical Prognosis in Acute Coronary Syndrome
In acute coronary syndrome (ACS), there is an increase in cortisol levels, as an expression of the stress response, and C-reactive protein, as an expression of the inflammatory response, which are in turn associated with changes…
- Conditions
- Acute Coronary Syndrome, Stress Hyperglycemia, Cortisol; Hypersecretion, Inflammatory Response
- Trial name
- NCT06513611
- Testing
- Serum cortisol.
- Where
- Argentina
- Volunteers
- 150 people
- Sponsor
- Hospital de Clinicas José de San Martín
Preterm Infants
Pain Reactivity to Non-Pharmacological Interventions Across Repeated Routine Heel-Sticks in Preterm Infants in a Neonatal Intensive Care Unit
Switzerland is having one of the highest premature rates in Europa and most of the preterm neonates need neonatal intensive care.
- Trial name
- PAMINA (NCT00758511)
- Testing
- 25% Sucrose, facilitated tucking, Sucrose and facilitated tucking
- Where
- Switzerland
- Volunteers
- 71 people
- Sponsor
- University of Basel
Dialysis Hypotension
Steroids on Intra-dialytic Hypotension
Symptomatic hypotension during (or immediately following) hemodialysis complicates 5 to 30 percent of all dialysis treatments and is associated with increased morbidity and mortality.
- Trial name
- NCT03465007
- Testing
- Hydrocortisone, Normal saline
- Where
- Jordan
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- University of Jordan
Cushing Syndrome
Extension Study to Evaluate the Safety of Long-Term Use of Relacorilant in Patients With Cushing Syndrome
This is an open-label extension study to evaluate the long-term safety of relacorilant in patients with endogenous Cushing syndrome who successfully completed participation in a Corcept-sponsored study of relacorilant and may…
- Trial name
- NCT03604198
- Testing
- relacorilant
- Where
- 48 sites in United States, Austria and 8 more
- Volunteers
- 125 people
- Sponsor
- Corcept Therapeutics
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