Clinical trials: Cortisol
Disorder of Endocrine Ovary, Hypersecretion; Cortisol
Pathogenesis of Functional Hypothalamic Amenorrhea
This is a randomized pilot study of the use of cognitive behavior therapy versus observation to treat functional hypothalamic amenorrhea, often termed stress-induced anovulation.
- Conditions
- Disorder of Endocrine Ovary, Hypersecretion; Cortisol, Metabolic Disturbance, Stress, Psychological
- Trial name
- NCT01674426
- Testing
- Cognitive behavior therapy
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- University of Pittsburgh
Sarcoidosis
Hair Cortisol and Testosterone Levels in Patients With Sarcoidosis
The investigators studied whether scalp hair cortisol and testosterone levels differed between sarcoidosis patients both with and without fatigue and healthy controls.
- Trial name
- NCT03108547
- Testing
- Determination of scalp hair steroids
- Volunteers
- 32 people
- Sponsor
- Erasmus Medical Center
Ocular Inflammation, Ocular Prostheses
Comparison of Topical Treatment for Inflammatory Secretions of the Conjonctiva (Patients With Ocular Prostheses)
We propose to evaluate the efficacy of treatment with Hydrocortisone and Dexamethasone (in a cross-over design) in patients with ocular prostheses and significant functional discomfort.
- Trial name
- CRYSTAL (NCT05668455)
- Testing
- Hydrocortisone, Dexamethasone, Povidone
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Agnes
Prostate Cancer
The Effect of Intrarectal Ice Application on Pain, Anxiety, Cortisol Level, Complication Development in Transrectal Ultrasonography Guided Prostate Biopsy
Transrectal ultrasound (TRUS)-guided prostate biopsy is one of the most commonly performed urological procedures today. This technique involves the insertion of a needle through the rectal mucosa to access the prostate.
- Trial name
- NCT06998121
- Testing
- Intrarectal ıce application
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people
- Sponsor
- Mersin University
Combined Oral Contraceptive Cessation
CBG Normalization After Discontinuation of COC's
In this study, the investigators aim to examine after which duration corticosteroid-binding globulin (CBG) and total cortisol concentrations return to normal after cessation of the combined oral contraceptive pill in healthy…
- Trial name
- NCT06802211
- Where
- Netherlands
- Volunteers
- 24 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Menopause
Cortisol Levels on Menopausal Symptoms - Ancillary (Addendum) Study to Protocol 16997
This is an ancillary study to Protocol 16997 to examine the stress hormone level in women with menopausal symptoms. This ancillary project will collect additional data from the 45 subjects enrolled in Protocol 16997 (no subjects…
- Trial name
- NCT00950781
- Testing
- ACTH
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center
Wellbeing, Healthy
PROMOTE: The Effect of a Six Week Prebiotic Supplementation on Wellbeing of Young Adults.
The study will investigate whether taking a prebiotic for six weeks helps to reduce morning cortisol levels in healthy young adults with mild to moderate stress compared to a placebo.
- Conditions
- Wellbeing, Healthy, Mental Health
- Trial name
- PROMOTE (NCT06566157)
- Testing
- Prebiotic, Maltodextrin (Corn)
- Where
- United Kingdom
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Southampton
Seborrheic Dermatitis
Topical Terbinafine Versus Hydrocortisone Combined With Oral Itraconazole for Seborrheic Dermatitis
The goal of this clinical trial is to compare two creams used together with oral itraconazole in adults with moderate-to-severe seborrheic dermatitis.
- Trial name
- NCT07906886
- Testing
- Itraconazole, Terbinafine 1% cream, Hydrocortisone 1% cream
- Where
- 2 sites in Vietnam
- Volunteers
- 76 people
- Sponsor
- Can Tho University of Medicine and Pharmacy
Stress Disorders
Allostatic Load Assessment Using Hair Cortisol and Dehydroepiandrosterone Sulfate Concentration in Patients Affected by Periodontal Disease
This study was designed with a double-blind observation design on a population of patients with different periodontal conditions.
- Trial name
- NCT07443605
- Testing
- stressed periodontal patients
- Where
- Italy
- Volunteers
- 42 people
- Sponsor
- University of Trieste
Percutaneous Transluminal Coronary Angioplasty
Effect of Non-pharmacological Anti-anxiety Exercises on Perceived Stress and Cortisol Level Before Elective Per Cutaneous Transluminal Coronary Angioplasty
Effect of non-pharmacological anti-anxiety exercises on Perceived Stress and cortisol level before elective percutaneous transluminal coronary angioplasty
- Trial name
- NCT06534294
- Testing
- reflexology, breathing exercise, standard care
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- October 6 University
Post Spinal Anaesthesia Hypotension
Comparison Between Intravenous Hydrocortisone and Ondansetron in Prevention of Post Spinal Anesthesia Hypotension
The purpose of this study is to assess and contrast the effectiveness of intravenous ondansetron and intravenous hydrocortisone in avoiding spinal anesthesia-induced hypotension.
- Trial name
- NCT06930456
- Testing
- hydrocortisone, ondansetron
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Nada kamel Elgamal
Cirrhosis With Ascites
Adrenal Insufficiency in Cirrhotics With Ascites. Effects of Hydrocortisone on Renal and Haemodynamic Function
Relative adrenal insufficiency (RAI) is an well known condition in patients with septic shock. Liver failure (including chronic liver failure)and sepsis are both characterized by hyperdynamic circulatory failure (with low…
- Trial name
- AILD (NCT00657306)
- Testing
- hydrocortisone, dextrose solution 5%
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- University of Turin, Italy
Breast Neoplasms, Survivorship
Impact of Acceptance and Commitment Therapy on Early Stage Breast Cancer
The purpose of this randomized controlled trial is to evaluate the effectiveness of an empirically supported psychosocial treatment, Acceptance and Commitment Therapy, in facilitating improved quality of life, benefit-finding…
- Conditions
- Breast Neoplasms, Survivorship, Stress
- Trial name
- ACT (NCT01164930)
- Testing
- Acceptance and Commitment Therapy
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- San Jose State University
Healthy
Pharmacokinetics and Bioavailability of Hydrocortisone Acetate Suppositories
This study will be an open label, single dose, randomized, 2 way (2 period) crossover study in healthy adult subjects at a single study center.
- Trial name
- NCT02671058
- Testing
- Cortenema, Hydrocortisone Acetate
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Cristcot LLC
Suprascapular Nerve Block, Axillary Nerve Block
The Effect of Dexmedetomidine for Suprascapular Nerve Block With Axillary Nerve Block
Suprascapular nerve block (SSNB) is most commonly used for relieving postoperative pain of arthroscopic rotator cuff repair and it can be used in combination with axillary nerve block (ANB).
- Conditions
- Suprascapular Nerve Block, Axillary Nerve Block, Dexmedetomidine, Arthroscopic Rotator Cuff Repair
- Trial name
- NCT04398589
- Testing
- Dexmedetomidine injection, Saline injection
- Where
- South Korea
- Volunteers
- 46 people
- Sponsor
- Chuncheon Sacred Heart Hospital
Asthma
A Phase I Study in Asthma Patients Evaluating the Effect of Doses of FlutiForm™ on the Amount, if Any, of Cortisol Produced by the Adrenal Glands
The medications being used in this study are individually approved by the Food and Drug Administration (FDA). The medication under investigation is a combination of the two medications in one inhaler.
- Trial name
- NCT00657774
- Testing
- FlutiForm 250/10 ug, FlutiForm 100/10 ug, Oral Prednisone 10mg
- Where
- 19 sites in United States
- Volunteers
- 160 people
- Sponsor
- SkyePharma AG
Dental Implantation Accuracy
Accuracy of 3D Printed Custom-Made Registration Method for Dynamic Navigation Implant Surgery Using Mininavident in the Esthetic Zone: A Clinical Trial
This clinical trial evaluates the accuracy of a 3D printed custom-made registration method for dynamic navigation implant surgery using the Mininavident system in the esthetic zone of the anterior maxilla.
- Trial name
- NCT07199153
- Testing
- D Printed Custom Registration Marker for Dynamic Navigation
- Where
- Egypt
- Volunteers
- 10 people
- Sponsor
- Sherif Aly Sadek
Bronchopulmonary Dysplasia
Phase II Pilot Study of Early Cortisol Replacement to Prevent Bronchopulmonary Dysplasia
OBJECTIVES: I. Estimate the efficacy of cortisol replacement therapy during the first 12 days of life for prevention of bronchopulmonary dysplasia. II.
- Trial name
- NCT00004669
- Testing
- hydrocortisone
- Volunteers
- 40 people
- Sponsor
- National Center for Research Resources (NCRR)
Chronic Insomnia
Restorative Effects of Sleep on Everyday Health and Wellbeing: A Treatment Study
The purpose of this study is to evaluate the mechanisms through which Cognitive Behavioral Therapy for Insomnia (CBT-I) leads to improvements in sleep and sleep-related daytime outcomes, specifically as it relates to cortisol and…
- Trial name
- RESET (NCT07156383)
- Testing
- Cognitive Behavioral Therapy for Insomnia
- Where
- United States
- Volunteers
- 115 people
- Sponsor
- University of Notre Dame
Obesity
Neuroendocrine Modulation of Metabolic Effects in Overweight Adolescents
This study will examine hormonal differences in ghrelin and growth hormone in obese and normal weight adolescents and their relationship to body composition and insulin resistance.
- Trial name
- NCT00140842
- Where
- United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
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