Clinical trials: Cortisol
Addison's Disease
Exercise Capacity and Recovery in Addison's Disease
Exposure to stress alters the activity of the adrenomedullary, adrenocortical and sympathetic nervous system, depending on the type and intensity of the stressor.
- Trial name
- NCT01657123
- Testing
- ergometry
- Where
- Netherlands
- Volunteers
- 20 people
- Sponsor
- UMC Utrecht
Healthy
Comparison of Blood Levels of Two Formulations of the Selective Hormone Receptor Modulator CDB-2914
This study will compare blood levels of the drug CDB-2914 in healthy women receiving the compound in crystalline powder form with the blood levels of women receiving an identical dose of the drug in micronized form.
- Trial name
- NCT00041899
- Testing
- CDB-2914, COB-2914
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Osteoporosis, Cortisol Excess
Prevalence of Hidden Hypercortisolism in Osteoporosis
The goals of this observational study are the following: i) to assess the prevalence of hidden hypercortisolism (HidHyCo) in a sample of osteoporotic patients; ii) to compare the clinical characteristics between…
- Trial name
- OSTCOR (NCT05762549)
- Where
- 5 sites in Italy
- Volunteers
- 1,000 people
- Sponsor
- Istituto Auxologico Italiano
Dermatitis, Atopic
Efficacy/Safety Study to Explore a New Topical Formulation in Atopic Dermatitis
The study shall explore whether treatment of atopic dermatitis is equally effective with Phoenix medical device as compared to standard therapy (Hydrocortisone cream).
- Trial name
- Phoenix (NCT01691209)
- Testing
- Phoenix (BAY81-2996), 1% Hydrocortison cream
- Where
- Germany
- Sponsor
- Bayer
Pregnancy, Stress
Effects of Stress on Glucose Tolerance During Pregnancy
The objective of the study is to investigate the effect of stress on glucose tolerance during pregnancy. The main objectives of the study are to investigate if various measures of stress (stressful life events, the perceived…
- Conditions
- Pregnancy, Stress, Gestational Diabetes
- Trial name
- NCT01707784
- Where
- Switzerland
- Volunteers
- 203 people, healthy volunteers welcome
- Sponsor
- University of Lausanne Hospitals
Coronary Artery Disease, Valvular Heart Disease
The Cortisol Levels During Cardiac Surgery. The Comparison Between Etomidate and Thiopentone
During induction for cardiac surgery, patient hemodynamic stability is achieved by using anesthetic drugs which least affects hemodynamics such as benzodiazepines, etomidate.
- Trial name
- NCT01495949
- Testing
- etomidate, thiopentone
- Where
- Thailand
- Volunteers
- 92 people
- Sponsor
- Mahidol University
Cushings Syndrome
Saliva Cortisol Measurement as a Screening Test for Suspicious Cushings Syndrome in Children.
Cortisol overproduction ( Cushings syndrome) is a condition where the patient have a special fat distribution, with accumulation of fat around the abdomen and in the neck, with thinner limbs and weak musculature.
- Trial name
- NCT02646553
- Testing
- Children refered to the obesity clinic
- Where
- Norway
- Volunteers
- 70 people
- Sponsor
- Haukeland University Hospital
Mild Autonomous Cortisol Secretion (MACS)
Metyrapone Versus Osilodrostat in Patients With Metabolic Autonomous Cortisol Secretion (MACS)
This study will compare the efficacy and safety of the two 11β-hydroxylase inhibitors-metyrapone and osilodrostat-in patients with MACS.
- Trial name
- MOMACS (NCT07268222)
- Testing
- Metyrapone 250 mg Oral Tablets, Osilodrostat 1 MG, adrenalectomy
- Where
- Greece
- Volunteers
- 150 people
- Sponsor
- Laikο General Hospital, Athens
Stress, Signs and Symptoms, Digestive
The Acute Effect of Coffee Consumption on Stomach, Self-reported Gastrointestinal Symptoms and Stress.
This study investigated the acute effect of the consumption of four different kinds of coffee (hot and cold instant coffee, cold espresso and hot filter coffee) with the same caffeine content on salivary gastrin, cortisol and…
- Conditions
- Stress, Signs and Symptoms, Digestive, Blood Pressure, Increased Secretion of Gastrin
- Trial name
- NCT02253628
- Testing
- Cold espresso, Hot instant coffee, Cold instant coffee
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Agricultural University of Athens
Sleep, Morning Alertness
Investigating the Effects of Dairy Phospholipids on Sleep and Daytime Function in Healthy Adults.
The aim of the study is to investigate the effects of 6- and 12- week supplementation of a bioactive whey protein concentrate drink containing dairy phospholipids on sleep and daytime function parameters in healthy adults.
- Conditions
- Sleep, Morning Alertness, Evening Alertness, Diurnal Cortisol
- Trial name
- NCT06663865
- Testing
- Active
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Northumbria University
School Readiness, Developmental Delays
Early Intervention Foster Care: A Prevention Trial
The Early Intervention Foster Care [EIFC] project is an efficacy trial of the Oregon Social Learning Center Multidimensional Treatment Foster Care Program, a preventive intervention that targets 3 commonly co-occurring variables…
- Trial name
- EIFC (NCT00701194)
- Testing
- Early Intervention Foster Care (EIFC)
- Where
- United States
- Volunteers
- 177 people
- Sponsor
- Oregon Social Learning Center
Anorexia Nervosa, Hypothalamic Amenorrhea
Hormone Dynamics and Bone Mineral Density in Anorexia Nervosa v. Hypothalamic Amenorrhea
The purpose of this study is to determine whether the hormone dynamics in women with anorexia nervosa and hypothalamic amenorrhea is related to bone loss in those populations.
- Conditions
- Anorexia Nervosa, Hypothalamic Amenorrhea, Obesity
- Trial name
- NCT00556036
- Where
- United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Motivation
Motivational Interviewing Inadequate Milk and Cortisol
Motivational interviewing is a technique used in many fields. No study has been found in national and international databases investigating the effect of motivational interviewing on the perception of insufficient milk…
- Trial name
- NCT06344663
- Testing
- motivational interview
- Where
- Turkey (Türkiye)
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Kahramanmaras Sutcu Imam University
Community-acquired Pneumonia, Influenza, COVID-19
Randomized, Embedded, Multifactorial Adaptive Platform Trial for Community- Acquired Pneumonia
REMAP-CAP is a randomised, embedded, multifactorial, adaptive platform trial for community-acquired pneumonia. The purpose of this study is to evaluate the effect of a range of interventions to improve outcome of patients…
- Trial name
- REMAP-CAP (NCT02735707)
- Testing
- Ceftriaxone, Moxifloxacin or Levofloxacin, Piperacillin-tazobactam
- Where
- 408 sites in United States, Australia and 27 more
- Volunteers
- 20,000 people
- Sponsor
- UMC Utrecht
End-Stage Renal Disease, Hemodialysis Complication
Effects of Mindfulness Meditation on Hemodialysis Patients
Objective: This study aimed to examine the effects of mindfulness meditation on the quality of sleep, perceived stress, serum cortisol, and C-reactive protein in end-stage renal disease patients undergoing hemodialysis.
- Trial name
- RCT (NCT06936293)
- Testing
- Mindfulness Meditation
- Where
- Kuwait
- Volunteers
- 56 people
- Sponsor
- University of Jordan
Substance Abuse Disorders
Study of Smoking Abstinence
Background: Relapse following cigarette abstinence remains a common problem for smokers who are attempting to quit. Most research has focused on the acute withdrawal phase that occurs within the first 48 hours to 1 week after…
- Trial name
- NCT01035632
- Where
- United States
- Volunteers
- 210 people
- Sponsor
- National Institute on Drug Abuse (NIDA)
PTSD, Acute Stress Disorder
PTSD Prevention Using Oral Hydrocortisone
There is currently no evidence-based intervention for individuals exposed to trauma that is designed to aid recovery and prevent the development of post-traumatic stress disorder (PTSD).
- Conditions
- PTSD, Acute Stress Disorder, Trauma-related Stressor
- Trial name
- NCT04924166
- Testing
- Hydrocortisone
- Where
- 3 sites in United States, Israel
- Volunteers
- 201 people
- Sponsor
- Rachel Yehuda
Pregnancy Related, Cannabis Use
Effects of Pregnancy-associated Hormones on THC Metabolism in Women
Cannabis use is prevalent among pregnant women, but the effects of use on both the developing fetus and pregnant woman are unknown.
- Trial name
- PrECEPT (NCT04374773)
- Testing
- Dronabinol
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Washington
Pregnancy Complications, Mental Health Issue
Psychobiological Interventions in Pregnancy
This randomized control trial will evaluate whether a physical activity intervention can improve mental health and biologic markers of stress in pregnant people with depressive or anxiety symptoms.
- Conditions
- Pregnancy Complications, Mental Health Issue, Depression, Anxiety, Pregnancy, High Risk
- Trial name
- PIP (NCT06430853)
- Testing
- Step count goal, Actigraph watch
- Where
- United States
- Volunteers
- 88 people
- Sponsor
- Stanford University
Headache
Comparative Study Between Hydrocortisone and Mannitol in Treatment of Postdural Puncture Headache
Fifty patients of both sex, aged 18-50 years and ASA I and II undergoing elective lower abdominal and pelvic surgery under spinal anesthesia were included in this randomized double-blind study.
- Trial name
- NCT02760862
- Testing
- hydrocortisone 100mg., mannitol 20% intravenous fluid
- Volunteers
- 50 people
- Sponsor
- Ain Shams University
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