Clinical trials: Cortisol
Cushing Syndrome
Long Term Post Operative Follow-Up of Cushing Syndrome
Although most patients with hypercortisolism can be diagnosed and treated the long-term effects of hypercortisolism and its treatment are unknown. This study will attempt to answer the following questions: 1.
- Trial name
- NCT00029952
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Depressive Disorder
The Antidepressant Effect of Right Temporal Low Frequency rTMS Compared to Sham
The aim of the present study is to compare the antidepressant effect of low frequency rTMS applied over the right temporal cortex with sham stimulation.
- Trial name
- NCT00622947
- Testing
- right temporal low frequency (1 hz) rTMS
- Where
- Denmark
- Volunteers
- 10 people
- Sponsor
- University of Aarhus
Impingement Syndrome, Subacromial Impingement Syndrome
Effect Of Hydrocortisone Phonophoresis Versus Iontophoresis In Patients With Subacromial Impingement Syndrome
The purpose of this study will be to compare the efficacy of adding hydrocortisone phonophoresis or iontophoresis on pain, function, range of motion and shoulder external rotation isometric strength in patients with subacromial…
- Trial name
- NCT05919121
- Testing
- Therapeutic exercise, hydrocortisone phonophoresis, hydrocortisone iontophoresis
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Horus University
Septic Shock, Critical Illness
Evaluation of Hydrocortisone, Vitamin C and Thiamine for the Treatment of Septic Shock
Despite recent medical advances, sepsis and septic shock remain a major cause of death. Sepsis is a syndrome with a wide array of physiologic, pathologic, and biochemical abnormalities.
- Trial name
- HYVITS (NCT03380507)
- Testing
- Triple therapy group
- Where
- Qatar
- Volunteers
- 106 people
- Sponsor
- Hamad Medical Corporation
Cocaine-Related Disorders, Cocaine Addiction
Effects of Corticorelin Administration on Dopamine Transmission, Craving, and Mood in Cocaine Dependence
This study will, in a sample of cocaine-dependent and healthy control subjects, administer corticorelin and compare dopamine release between groups.
- Conditions
- Cocaine-Related Disorders, Cocaine Addiction, Substance-Related Disorders
- Trial name
- NCT01984177
- Testing
- Corticotropin-Releasing Hormone
- Where
- Canada
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Centre for Addiction and Mental Health
Adrenal Cortex Diseases, Infant Morbidity
Adrenal Responsiveness During the Perioperative Period in Children Undergoing Congenital Cardiac Surgery
Our objective was to determine whether a standard 1mg/kg intraoperative dose of dexamethasone results in similar drug levels for all patients and to characterize the relationship between these drug levels and the innate stress…
- Trial name
- NCT01839812
- Testing
- Cosyntropin
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Mayo Clinic
Intensive Care Unit Patients, Pain Management
Effects of Voice Records on Patient Outcomes Surgical Intensive Care Unit
This randomized kontrolled study is aimed to contribute to the literature on recognising, evaluating and reducing stress in the intensive care unit, which is one of the main responsibilities of surgical nurses, and to increase…
- Conditions
- Intensive Care Unit Patients, Pain Management, Stress Response
- Trial name
- NCT07007754
- Testing
- Voice recording playback
- Where
- Turkey (Türkiye)
- Volunteers
- 69 people
- Sponsor
- Aydin Adnan Menderes University
Dry Eye
Clinical Efficacy of Topical Hydrocortisone 0.335% (Softacort®) in Patients With Chronic Dry Eye Disease and Associated Ocular Surface Inflammation
Dry eye disease (DED) is a highly prevalent ocular condition and induces a significant burden to the affected patients. Regardless of the underlying etiology, DED is associated with increased inflammation of the entire ocular…
- Trial name
- NCT03907865
- Testing
- Softacort
- Where
- Austria
- Volunteers
- 60 people
- Sponsor
- Medical University of Vienna
Cushing's Syndrome
An Extension Study of CORLUX in the Treatment of Endogenous Cushing's Syndrome
Participants in study C-1073-400 (NCT00569582) will be invited to participate in this extension study to examine the long term safety of mifepristone in the treatment of the signs and symptoms of endogenous Cushing's syndrome.
- Trial name
- NCT00936741
- Testing
- mifepristone
- Where
- 15 sites in United States
- Volunteers
- 30 people
- Sponsor
- Corcept Therapeutics
Depression, Inflammation
Simvastatin and Emotional Processing (OxSTEP)
Simvastatin is being employed because it is a 'statin'. As a drug class, statins have broad anti-inflammatory properties. Low-level inflammation is thought to be a potentially important mediator of the effects of psychosocial…
- Trial name
- OxSTEP (NCT04973800)
- Testing
- Simvastatin 20mg
- Where
- United Kingdom
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Bladder Cancer
Stress-reducing Intervention in Urothelial Carcinoma
The aim of this interventional study is to test the heart-rate variability biofeedback intervention (HRV BI) in patients with muscle-infiltrating bladder carcinoma (MIBC) treated with chemotherapy based on cisplatin in…
- Trial name
- NCT06269536
- Testing
- HRV biofeedback
- Where
- Slovakia
- Volunteers
- 50 people
- Sponsor
- Comenius University
Community Acquired Pneumonia (CAP)
Comparing Hydrocortisone and Prednisolone for Community Acquired Pneumonia (CAP)
The goal of this cluster randomized controlled trial is to determine the optimal treatment for community aquired pneumonia (CAP).
- Trial name
- NCT06892197
- Testing
- Methylprednisolone (drug), hydrocortisone
- Where
- 14 sites in Denmark
- Volunteers
- 1,600 people
- Sponsor
- Copenhagen Respiratory Research
Hydrocortisone, Depression
Exploring the Effects of Corticosteroids on the Human Hippocampus
Chronic corticosteroid (CS) exposure is associated with changes in memory and the hippocampus in both humans and in animal models.
- Conditions
- Hydrocortisone, Depression, Healthy Volunteers
- Trial name
- NCT03896659
- Testing
- Hydrocortisone Oral
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Adrenal Hyperplasia, Congenital, 21-hydroxylase Deficiency
Adrenocortical Functions in Women With Nonclassical 21-hydroxylase Deficiency.
The risk of adrenal insufficiency in patients with nonclassical congenital adrenal hyperplasia due to 21-hydroxylase deficiency is not well documented.
- Trial name
- EVAF-21 (NCT01862380)
- Testing
- Functional explorations
- Where
- France
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
No Disease or Condition is Being Studied
Acute Psychological and Physiological Effects of Cannabigerol
The purpose of this study is to examine the acute effects of cannabigerol (CBG) on various psychological (e.g., anxiety, stress, mood, memory, impairment, intoxication, side effects) and physiological (blood pressure, cortisol…
- Trial name
- CBG (NCT06638996)
- Testing
- CBG Intervention
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Washington State University
PreTerm Neonate
Effect of Nursing Interventions on Pain and Salivary Cortisol Levels During Heel Stick in Preterm Newborns
Babies born before the thirty-seventh gestational week are called preterm or premature. Most preterm newborns require Neonatal Intensive Care Unit (NICU) care depending on their gestational age and clinical condition.
- Trial name
- NCT06628232
- Testing
- pacifier with breast milk, heel heating, interventions combined
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Namik Kemal University
Oral Lichen Planus Related Stress
Serum Cortisol Levels in Patients With Anxiety and Depression With Symptomatic Oral Lichen Planus
Oral lichen planus (OLP) is a T-cell mediated chronic immunological disease directed to a still unknown antigen. It is a mucocutaneous and a psychosomatic disorder, with unknown prevalence rate; however studies suggest an…
- Trial name
- NCT03011658
- Testing
- venepuncture
- Where
- India
- Volunteers
- 60 people
- Sponsor
- Panineeya Mahavidyalaya Institute of Dental Sciences & Research Centre
Quality of Life for Geriatric Patients.
Efficacy Study of Autosuggestion for Quality of Life of Geriatric Patients
The objective is to analyze the efficacy of autosuggestion for geriatric patients's quality of life and its impact to psycho-neuro-endocrine-immune pathways. The primary outcome is quality of life.
- Trial name
- ESAQoGe (NCT01681056)
- Testing
- Autosuggestion for 30 days
- Where
- Indonesia
- Volunteers
- 51 people
- Sponsor
- Universitas Indonesia
Preoperative Anxiety
Evaluation the Preoperative Anxiety Level of the Surgeons
Many studies are present about the preoperative anxiety among patients. But the preoperative anxiety of the surgeons is not studied yet.
- Trial name
- NCT04413981
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Adana City Training and Research Hospital
Sepsis
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Sepsis and Septic Shock
In this prospective clinical study, the investigators compare the outcome and clinical course of consecutive septic participants treated with intravenous vitamin C, hydrocortisone, and thiamine (treatment group) with a control…
- Trial name
- HYVCTTSSS (NCT03258684)
- Testing
- Hydrocortisone, Vitamin C, and Thiamine, Normal saline
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Zhujiang Hospital
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