Clinical trials: Cortisol
Sleep Apnea, Sleep Disordered Breathing
Sleepiness and the Effects of CPAP on Salivary Cortisol and Alpha-Amylase Levels in Patients With Sleep Apnea
Patients with Obstructive Sleep Apnea Syndrome (OSAS) will evidence higher levels of salivary cortisol and alpha-amylase levels prior to use of placebo and continuous positive airway pressure (CPAP) and will evidence a decrease…
- Trial name
- NCT01196117
- Testing
- 14 days of CPAP therapy
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Medical College of Wisconsin
PTSD - Post Traumatic Stress Disorder
Initial Study Sesting Efficacy and Tolerability of PT150 for PTSD in Veterans
The purpose of this study is to test the drug PT150, which blocks glucocorticoid receptor (GR) signaling, for treatment of PTSD in Veterans, and establish a safety and efficacy profile that will inform the design of future…
- Trial name
- NCT07187011
- Testing
- PT150
- Where
- 2 sites in United States
- Volunteers
- 120 people
- Sponsor
- San Diego Veterans Healthcare System
Stress Reaction
Validity for Stress Reduction of Virtual Reality Intervention
The purpose of this study is to verify the effect of virtual reality (VR) intervention on stress reduction for workers. After inducing stress by the Socially Evaluated Cold Pressure Test (SECPT), Investigators should explore…
- Trial name
- NCT07415239
- Testing
- virtual reality intervention, control intervention
- Where
- South Korea
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Dental Implant
Computer-guided Versus Free- Hand Immediate Implant Placement
Patients with fractured anterior teeth indicated for extraction will be recruited to the study. After Extraction of the tooth the socket will be evaluated and if eligible for immediate implant placement, implants will be placed…
- Trial name
- RCT (NCT03211819)
- Testing
- immediate implant placement
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Diabetes, Hypertension
Evaluation Of Stress Response In Diabetic Hypertensive Patients
In this research, we aimed to examine salivary cortisol changes in the cognitive stress response of patients with Hypertension + Diabetes Mellitus (HT+DM) and Hypertension (HT) and to determine the differences between them.
- Trial name
- NCT05662930
- Testing
- First arithmetic problem solving, Second arithmetic problem solving, Third arithmetic problem solving
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people
- Sponsor
- Istanbul University
Adrenocortical Carcinoma
Study of Relacorilant in Combination With Pembrolizumab for Patients With Adrenocortical Carcinoma Which Produces Too Much Stress Hormone (Cortisol)
This study will investigate the safety and efficacy of Relacorilant in combination with Pembrolizumab for Patients with Adrenocortical Carcinoma which Produces Too Much Stress Hormone (Cortisol).
- Trial name
- NCT04373265
- Testing
- Relacorilant, Pembrolizumab
- Where
- 6 sites in United States
- Volunteers
- 15 people
- Sponsor
- Corcept Therapeutics
Missing Tooth
Guided Bone Regeneration Around Immediate Implants
An important result of healing after tooth extraction is a reduction in dimensions of the remaining bone at that site. This reduction of bone volume precludes successful restoration of the space using a dental implant.
- Trial name
- NCT01628367
- Testing
- Minimally Traumatic Tooth Extraction, Immediate Implant Placement, Bone Graft Placement
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Systolic Heart Failure
Hair Cortisol and Testosterone in Heart Failure
The purpose of this study is to determine whether hair cortisol and testosterone levels correlate with heart failure status in patient with chronic congestive heart failure.
- Trial name
- NCT01139697
- Testing
- Hair sampling
- Where
- Israel
- Volunteers
- 46 people
- Sponsor
- Meir Medical Center
Mental Health Wellness 1
Onnit Labs New Mood Supplementation in Healthy College Students
The primary purpose of this study is to assess the effectiveness of ONNIT Lab's New Mood™ dietary supplement in supporting optimal mood balance and reducing daily stress among collegiate-aged men and women.
- Trial name
- NCT05109923
- Testing
- Multi-Ingredient Herbal Supplement
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- University of Idaho
Socket Shield, Socket Preservation
Hard and Soft Tissue Changes Following Vestibular Socket Preservation Versus Ice Cream Cone Technique for Management of Defective Fresh Extraction Sockets
Evaluation of hard and soft tissue changes following vestibular socket preservation versus ice cream cone technique for management of defective fresh extraction sockets in the esthetic zone.
- Trial name
- NCT06590168
- Testing
- Socket Preservation by vestibular socket therapy, Socket Preservation by icecream cone technique
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cairo University
Depression, Behavioral Problems
Dyadic Therapy for Mothers and Children
This study compares the effectiveness of Child Parent Psychotherapy to that of usual care (defined as: referral to therapists in the community or Columbia University Medical Center) in improving maternal depressive symptoms and…
- Trial name
- NCT02123160
- Testing
- Child Parent Psychotherapy (CPP), Control (usual treatment)
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- New York State Psychiatric Institute
TRANSRECTAL ULTRASOUND-GUIDED PROSTATE BIOPSY
Effect of Intrarectal Ice Application on Pain, Anxiety, Cortisol Levels, Development of Complications, and Hospital Readmission in Transrectal Ultrasound-Guided Prostate Biopsy
The aim of this study is to determine the effect of intrarectal ice application on pain, anxiety, cortisol levels, development of complications (rectal bleeding, hematuria, urinary retention, anemia, infection, etc.), and…
- Trial name
- NCT07462390
- Testing
- Intrarectal ıce
- Where
- Turkey (Türkiye)
- Volunteers
- healthy volunteers welcome
- Sponsor
- Tarsus University
Alcohol Dependence
Learning to Resist the Urge: Inhibition Training in Abstinent Patients With Alcohol Use Disorders
The study aims to investigate the effects of a short computerized training as a therapeutic add-on to standard therapy in patients with alcohol-use disorder.
- Trial name
- INTRA (NCT02968537)
- Testing
- Alc-IT (50/50) (morning), Alc-IT (75/25) (morning), Control-training (morning)
- Where
- 3 sites in Switzerland
- Volunteers
- 242 people
- Sponsor
- University of Bern
Major Depressive Disorder, Anxiety Disorders
Brain Hippocampal Volume Relationship With Anxious Symptoms in Major Depressive Patients
The objective of this transversal study is to determine if there is a difference in the volume of the hippocampus with the degree of anxiety.
- Trial name
- NCT04430556
- Testing
- Sertraline
- Where
- Mexico
- Volunteers
- 30 people
- Sponsor
- Hospital Universitario Dr. Jose E. Gonzalez
Dry Eye Disease
Idroflog® for Treatment of Dry Eye Disease (IDROFLOG)
This study aims at demonstrating the non-inferiority of Idroflog compared to sodium hyaluronate 0.18% for the disease improvement of people with documented history of dry eyes and use of tear substitutes for at least 3 months.
- Trial name
- IDROFLOG (NCT05724056)
- Testing
- Idroflog®, Sodium Hyaluronate 0.18% (Vismed®)
- Where
- 5 sites in France
- Volunteers
- 130 people
- Sponsor
- Alfa Intes Industria Terapeutica Splendore s.r.l.
Sepsis, Septic Shock
Pilot Study on the Use of Hydrocortisone, Vitamin c and Tiamine in Patient With Sepsis and Septic Shock
Due to the high incidence, mortality and short and long term complications of sepsis and septic shock, it is necessary to look for strategies to try to minimize this impact.
- Trial name
- NCT04111822
- Testing
- red blood cells transfusion, tranexamic acid (TXA) and fibrinogen concentrate, on crystalloid fluid and Tranexamic acid
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Cristina Martinez
Healthy
Outcome Following Antidepressant Treatment on Possible Endo-Phenotypes for Major Depression
The purpose of this study is to determine whether outcome following antidepressant treatment can be used as a tool to evaluate endo-phenotypes for depression.
- Trial name
- NCT00386841
- Testing
- Escitalopram
- Where
- Denmark
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Stress Reaction
The Effects of Lactobacillus Plantarum on Cortisol, IgA and Alpha-amylase Levels in Human Saliva During Stress
In the present study the main goal has been to clarify the effect of the probiotic bacteria Lactobacillus plantarum 299v on the salivary cortisol level in young adults under examination stress.
- Trial name
- NCT02974894
- Testing
- Probiotic (Lactobacillus Plantarum)
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Lund University
Mental Health Wellness
Two Recovery Strategies at Work, Based on Mindfulness and Physical Exercise, on Levels of Stress and Biological Measures
The present study aims to compare the differential effects of mindfulness meditation (MBI) and physical exercise (PE) on different stress and health variables (self-report means and IgA and cortisol levels).
- Trial name
- ERME2 (NCT05557266)
- Testing
- Mindfulness-based intervention, Physical exercise
- Where
- Spain
- Volunteers
- healthy volunteers welcome
- Sponsor
- Universidad Nacional de Educación a Distancia
Bipolar Disorder, Schizophrenia
Sleep, Obesity and Mental Disease - Biological Markers for the Evaluation of Circadian Rhythmicity
Introduction 16.8% of the Danish adult population are obese (Body Mass Index> 30 kg / m2). Obesity increases the risk of lifestyle diseases such as type-2 diabetes and non-alcoholic fatty liver.
- Conditions
- Bipolar Disorder, Schizophrenia, Obesity, Circadian Rhythm Disorders
- Trial name
- SOMBER (NCT05413486)
- Testing
- Observational
- Where
- Denmark
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Esbjerg Hospital - University Hospital of Southern Denmark
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