Clinical trials: Cortisol
Depression Anxiety Disorder, Demography, Family
The Effect of Mindfulness-based Stress Reduction Programme Given to Infertile Women
Purpose of the Study This study aims to determine the effect of mindfulness-based stress reduction program given to infertile women on perceived stress, anxiety, depression and salivary cortisol.
- Conditions
- Depression Anxiety Disorder, Demography, Family, Awakening Early
- Trial name
- NCT06283693
- Testing
- mindfulness-based stress reduction
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Stress, Anxiety
Minerals and Botanicals for Acute Stress
The objective of this acute intervention study is to examine the potential of minerals combined with botanicals to demonstrate unique and synergistic effects on oscillatory brain activity, cognitive performance, and stress…
- Trial name
- NCT03262376
- Testing
- Minerals + Vitamins, Botanical A, Botanical B
- Where
- United Kingdom
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Leeds
Traumatic Brain Injury
Improving Well-Being After TBI Through Structured Volunteer Activity
The purpose of this project is to determine if participating in volunteer activity improves the psychological well-being of individuals with traumatic brain injury (TBI).
- Trial name
- NCT01728350
- Testing
- HOPE - Helping Others through Purpose and Engagement
- Where
- United States
- Volunteers
- 74 people
- Sponsor
- Craig Hospital
Osteoporosis, Bone Fracture
PATHophysiology of OSteoporosis: Role of Hidden Cortisol Excess and Its Predictors in Bone Fragility
Osteoporosis is a chronic skeletal disease which leads to a decrease in bone strength which increases the risk of fractures. Clinically overt hypercortisolism leads to hypertension, central obesity, diabetes and osteoporosis.
- Conditions
- Osteoporosis, Bone Fracture, Cortisol Excess
- Trial name
- PATHOS (NCT06324084)
- Where
- 5 sites in Italy
- Volunteers
- 1,500 people
- Sponsor
- Istituto Auxologico Italiano
Ulcerative Proctitis
Phase 3 Study to Evaluate the Safety and Efficacy of Hydrocortisone Acetate Suppositories
A randomized, multi-center, double-blind, three arm placebo-controlled study in male and non-pregnant, non-lactating female subjects aged 18 years to examine the safety and efficacy of two dosing regimens of hydrocortisone…
- Trial name
- NCT04469686
- Testing
- Twice daily 90 mg hydrocortisone acetate suppository administered with Sephure applicator
- Where
- 189 sites in United States, Bulgaria and 21 more
- Volunteers
- 200 people
- Sponsor
- Cristcot HCA LLC
Adrenal Insufficiency
Salivary Cortisol Measurement in Corticotrope Deficiency Substitution With Hydrocortisone.
Patients with adrenal insufficiency are most often overdosed with hydrocortisone. To date, there is no reliable marker that can reflect the quality of hydrocortisone substitution.
- Trial name
- NCT05457296
- Testing
- Hydrocortisone (capsule)
- Where
- 2 sites in Tunisia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Tunis El Manar
Discoloration, Tooth, Chip Tooth
Dental Photography and Numeric Shade Quantification as a Substitute to Conventional and Instrumental Shade Matching Techniques in the Esthetic Zone
Visual shade matching is the most common method, in which a color standard from a commercially available dental shade guide is compared to and matched with the target tooth.
- Conditions
- Discoloration, Tooth, Chip Tooth, Non Vital Teeth, Trauma Dental
- Trial name
- NCT04817579
- Testing
- Digital photography combined with eLABor_aid shade analyzing software, Spectrophotometer, Conventional visual shade matching
- Where
- Egypt
- Volunteers
- 10 people
- Sponsor
- Cairo University
Preoperative Anxiety, Cesarean Section
Effect of Video-Based Versus Verbal Preoperative Information on Anxiety and Cortisol Levels in Elective Cesarean Section
Preoperative anxiety is a common problem in patients undergoing elective cesarean section and may negatively affect perioperative outcomes through activation of the stress response, including increased cortisol levels.
- Conditions
- Preoperative Anxiety, Cesarean Section, Surgical Stress Response, Cortisol
- Trial name
- NCT07521592
- Testing
- Verbal Preoperative Information, Video-Based Preoperative Information
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people
- Sponsor
- Elazıg Fethi Sekin Sehir Hastanesi
Nightmare
Nightmare Deconstruction and Reprocessing vs. NightWare Wristband
The overall goal of this Phase IIa randomized controlled pilot trial is to assess the potential efficacy of two emerging treatments for post-trauma nightmares and to test the feasibility of study design and methods.
- Trial name
- NDR/NW (NCT06399874)
- Testing
- Nightmare Deconstruction and Reprocessing, NightWare
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Uniformed Services University of the Health Sciences
Healthy
Hair Biomarkers Study
Young children aged 0-4 years may be exposed to adverse childhood experiences (ACEs) and/or early life adversity (ELA), which are linked with worse physical and mental health across their lifespan.
- Trial name
- HBS-II (NCT07011082)
- Testing
- Stress preventative measures
- Where
- United States
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Stanford University
Obesity
Contribution of Salivary Cortisol in the Detection of Infra-clinic Cortisol Adenoma (ACIC)
The main objective of the study is to assess the sensitivity of the salivary cortisol dosage at 23 hours compared to the serum cortisol dosage at 8 am after overnight 1-mg dexamethasone suppression test (Suppression of serum…
- Trial name
- ACIC (NCT01156519)
- Testing
- Salivary Cortisol
- Where
- France
- Volunteers
- 514 people
- Sponsor
- Nantes University Hospital
Preeclampsia, Stress, Psychological
Stress Reduction in Formerly Preeclamptic Women; Sofa or Sports
The goal of this clinical trial is to evaluate stress and cardiovascular risk factors in women with preeclampsia in the medical history.
- Conditions
- Preeclampsia, Stress, Psychological, Stress, Physiological, Sports Physical Therapy
- Trial name
- SOS (NCT06402604)
- Testing
- Aerobic exercise training, Mindfulness Based Stress Reduction training
- Where
- 2 sites in Netherlands
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Cognitive Therapy, Control
Efficacy of Cognitive Behavioral Therapy and Hair Cortisol Concentration
Stress is considered as a risk factor for physical and mental health. For this reason, interventional programs focused on stress management have been developed.
- Trial name
- NCT03476200
- Testing
- Cognitive Behavioral Therapy
- Where
- Spain
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Universidad de Granada
Adrenal Insufficiency
Optimising Steroid Replacement in Patients With Adrenal Insufficiency
Adrenal insufficiency is a condition where the adrenal glands do not produce an adequate amount of steroid hormones. The aetiology of adrenal insufficiency can be primary or secondary.
- Trial name
- NCT03282487
- Testing
- Modified release hydrocortisone
- Where
- Ireland
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- The Adelaide and Meath Hospital, incorporating The National Children's Hospital
Septic Shock
Combination of Corticotherapy and Intensive Insulin Therapy for Septic Shock
This study will compare, in adults with septic shock, the safety and efficacy of a combination of moderate doses of corticosteroids and intensive insulin therapy to that of moderate doses of corticosteroids.
- Trial name
- COIITSS (NCT00320099)
- Testing
- recombinant human insulin, hydrocortisone, fludrocortisone
- Where
- 8 sites in France
- Volunteers
- 508 people
- Sponsor
- University of Versailles
Dietary Modification
Randomized Controlled Experiment of Dieting in Pairs
This study examined how dieting with a partner affects weight loss, diet adherence, psychological well-being, and cortisol.
- Trial name
- NCT02898844
- Testing
- Mixed Diet Condition, Both Diet Condition
- Volunteers
- 164 people, healthy volunteers welcome
- Sponsor
- A. Janet Tomiyama
Infant, Newborn, Infant, Low Birth Weight
Early Blood Pressure Management in Extremely Premature Infants
This trial tests the feasibility of enrolling 60 extremely preterm infants in a randomized, double-blinded study of blood pressure management within 12 months.
- Conditions
- Infant, Newborn, Infant, Low Birth Weight, Infant, Small for Gestational Age, Infant, Premature
- Trial name
- ELGAN BP (NCT00874393)
- Testing
- Dopamine, Hydrocortisone
- Where
- 17 sites in United States
- Volunteers
- 10 people
- Sponsor
- NICHD Neonatal Research Network
Adrenal Insufficiency
An Investigational Study of Hydrocortisone
This study will investigate a new drug called Infacort®; a newly-developed immediate release formulation of a well-established drug called hydrocortisone.
- Trial name
- NCT01960530
- Testing
- Hydrocortisone granules, Hydrocortisone Tablet, i.v. Hydrocortisone Injection
- Where
- United Kingdom
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Neurocrine UK Limited
Neck Pain Following Traffic Accident
Validating a Brief Screening Tool With Biomarkers for Prediction of Chronic Post Traumatic Neck Pain
Early screening of posttraumatic neck pain after accidents A clinical prediction tool with biomarkers predicting chronic posttraumatic neck pain.
- Trial name
- NCT06176209
- Testing
- screening tool with biomarkers for prediction of chronic post traumatic neck pain
- Volunteers
- 155 people
- Sponsor
- University of Southern Denmark
Allergic Conjunctivitis
Hydrocortisone Ophthalmic Ointment 0.5% for Treatment of Allergic Conjunctivitis
The purpose of this study is to determine the safety and effectiveness of hydrocortisone ophthalmic ointment compared to placebo in the treatment of Allergic Conjunctivitis.
- Trial name
- NCT01860664
- Testing
- hydrocortisone ophthalmic ointment 0.5%
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Koffler Vision Group
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