Clinical trials: Cortisol
Alcohol Drinking
Validation in Humans of Genes Involved in Alcohol Drinking, Stress-Induced Alcohol Drinking and Relapse
Aim of the project is to validate and functionally characterize the combined impact of candidate genes and stress exposure on drinking in adolescents.
- Trial name
- NCT00326742
- Testing
- Trier Social Stress Test
- Where
- Germany
- Volunteers
- 281 people, healthy volunteers welcome
- Sponsor
- Central Institute of Mental Health, Mannheim
Polycystic Ovary Syndrome
Cortisol Regulation in Polycystic Ovary Syndrome (PCOS)
The purpose of this study is to determine if insulin resistance (how well the body uses insulin and clears sugar) can affect cortisol levels in normal healthy women and women with polycystic ovary syndrome of all body weights.
- Trial name
- NCT00694759
- Testing
- pioglitazone, metformin
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Nurse, Attention
Effects of Aerobic Exercise Training on Nurses' Sleep Quality, Fatigue, Attention and Cortisol Profile
Shift work in nursing has been found to result in sleep disruption and sleep deprivation, and in sleepiness or fatigue at work. Slow reaction, insufficient attention and poor judgement often come with increased fatigue, which…
- Conditions
- Nurse, Attention, Aerobic Exercise, Sleep Quality
- Trial name
- NCT03759509
- Testing
- aerobic exercise
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University
Blood Pressure, Heart Rate
Hydrocortisone Per-treatment Decrease Side Effects of Protamine Sulfate
This study aims to compare the hemodynamic parameters within and between patients who received Protamine Sulfate (PS) with Hydrocortisone (HC) vs. Protamine Sulfate alone during cardiac surgeries.
- Conditions
- Blood Pressure, Heart Rate, Airway Pressure
- Trial name
- NCT04435912
- Testing
- Hydrocortisone 200mg IV
- Where
- Jordan
- Volunteers
- 200 people
- Sponsor
- University of Jordan
Bronchopulmonary Dysplasia, Encephalomalacia
Randomized Trial of Hydrocortisone in Very Preterm High-Risk Infants
The purpose of this study is to determine whether treatment of very preterm infants at high-risk for lung and brain injury with low dose hydrocortisone results in improved pulmonary and neurologic outcomes.
- Conditions
- Bronchopulmonary Dysplasia, Encephalomalacia, Premature Birth
- Trial name
- NCT00167544
- Testing
- Hydrocortisone
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- Nationwide Children's Hospital
Critically Ill
Salivary Cortisol in Intensive Care Unit
In critical illness, patients are highly stressed and should have elevated cortisol (stress hormone) secretion to adapt to stress.
- Trial name
- NCT02001207
- Testing
- Salivary cortisol test
- Where
- South Korea
- Volunteers
- 90 people
- Sponsor
- Seoul National University Hospital
Injuries, Whiplash
Association Between Low Cortisol Levels and Whiplash Syndrome
The investigators hypothesis is that low (or low relatively to the situation) cortisol levels might be a causative factor of whiplash injury or post traumatic stress disorder following road accidents.
- Trial name
- NCT02090309
- Testing
- Hydrocortisone, normal saline 0.9%
- Where
- 3 sites in Israel
- Volunteers
- 90 people
- Sponsor
- Soroka University Medical Center
Healhty
Autonomic and Peripheral Neurochemical Responses to Maximal Rowing Exercise
The goal of this observational study is to characterize autonomic, neuroendocrine, and peripheral neurochemical responses to maximal rowing exercise and early recovery in highly trained male athletes.
- Trial name
- NCT07661953
- Testing
- Maximal 6,000-m rowing ergometer test
- Where
- Poland
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Poznan University of Physical Education
Snake Bites
Improving Safety of Antivenom in People Bitten by Snakes
A study to increase the safety of polyvalent antivenom involving 1000 patients in three centres: low dose adrenaline, promethazine, \& hydrocortisone (alone and in combination) to prevent acute adverse reactions to antivenom in…
- Trial name
- NCT00270777
- Testing
- adrenaline, promethazine, hydrocortisone
- Where
- Sri Lanka
- Volunteers
- 1,000 people
- Sponsor
- University of Kelaniya
Lumbar Disc Herniation, Preoperative Anxiety
Comparison of Virtual Reality-Based and Routine Preoperative Education on Surgical Anxiety and Salivary Cortisol
This randomized controlled pilot study aims to compare the effects of virtual reality-based preoperative education and routine preoperative education on surgical anxiety in patients undergoing lumbar disc surgery.
- Trial name
- NCT07443111
- Testing
- Virtual Reality-Based Preoperative Education, Routine Preoperative Education
- Volunteers
- 56 people
- Sponsor
- Bezmialem Vakif University
Immediate Loading , Satellite Implant , Immediate Implant
Insertion of Immediate Cortical Satellite Implants With Immediate Loading
Statement of the problem: Based on the literature traditional immediate implant with immediate loading has high failure rate due to destructive horizontal forces, accordingly It was recommended for long time stress-free healing…
- Trial name
- NCT05782634
- Testing
- immediate satellite implant with immediate loading
- Where
- Egypt
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Cairo University
Healthy, Healthy Adult Participants
Muévete conCiencia: Exercise and Mind-Body Program for University Students
The goal of this clinical trial is to evaluate whether different physical exercise and mind-body interventions can improve executive functions and reduce stress in first-year university students.
- Trial name
- NCT07443904
- Testing
- Motor-Cognitive Dual-Task Exercise (DT), Tai Chi Mind-Body Exercise (TC), Cognitive Stimulation (CS)
- Where
- Chile
- Volunteers
- 297 people, healthy volunteers welcome
- Sponsor
- Universidad San Sebastián
Dental Implants, Dental Implants , Osseointegration , Marginal Bone Loss , Implant Stability
Periosteal Sutures Versus Titanium Tacks for Guided Bone Re-generation in the Aesthetic Zone: a Pilot Randomized Controlled Trial
This randomized controlled clinical study, titled "Periosteal sutures for fixation of composite bone substitutes in guided bone regeneration: a randomized controlled clinical study," is being conducted at the Dental Unit of…
- Conditions
- Dental Implants, Dental Implants , Osseointegration , Marginal Bone Loss , Implant Stability, Maxillary Alveolar Reconstruction
- Trial name
- NCT07330232
- Testing
- Periosteal mattress sutures for graft/membrane stabilization in guided bone regeneration Titanium tacks for graft/membrane stabilization in guided bone regeneration
- Where
- Chile
- Volunteers
- 40 people
- Sponsor
- University of Chile
Overweight and Obesity
Study of the Effects of Overfeeding on Glucocorticoids in Lean and Obese Subjects
Investigators suggest that in lean subjects cortisol increases in response to overfeeding and that this increase is blunted in obese subjects.
- Trial name
- Gluco-Food (NCT04482738)
- Testing
- High-calorie meal
- Where
- Switzerland
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Eleonora Seelig
Adrenal Insufficiency
Once-daily Oral Modified Release Hydrocortisone in Patients With Adrenal Insufficiency
This is a randomised, controlled, open, two-armed, two-period cross-over, multi-centre phase II/III study to assess the safety, tolerability and pharmacokinetics of once-daily oral modified-release hydrocortisone in comparison to…
- Trial name
- NCT00915343
- Testing
- hydrocortisone (modified release), oral tablet 20 and 5 mg, Hydrocortisone, oral tablet, 10 mg
- Volunteers
- 64 people
- Sponsor
- Shire
Endodontic Treatment
Stress Factors Induced by Patient and Young Clinicien During Endodontic Treatment
The aim of this pilot study is to examine the patient's induced stress and the young dentist's induced stress, during endodontic treatment.
- Trial name
- STRESSENDO (NCT03217760)
- Testing
- Endodontic treatment, VAS of stress, CORAH scale
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Hospital, Brest
Post Traumatic Stress Disorder
Hair Cortisol Level as a Predictor of PTSD Development
Post-traumatic stress disorder, PTSD, is one of the most prevalent psychiatric disorders. As casualties of motor vehicle accidents, criminal acts or terrorism are arriving to the ER, it is almost impossible to conclude who will…
- Trial name
- NCT01804426
- Where
- Israel
- Volunteers
- healthy volunteers welcome
- Sponsor
- Shalvata Mental Health Center
Diagnosis, Treatment
Chongqing Adrenogenic Autonomic Cortisol Secretion Cohort Study
To investige the etiology, pathogenesis, diagnosis and treatment of adrenogenic autonomic cortisol secretion in Chinese adults.
- Conditions
- Diagnosis, Treatment, Adrenogenic Autonomic Cortisol Secretion
- Trial name
- CONACSS (NCT05743933)
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Chongqing Medical University
Exercise Immunology, Exercise Physiology
Effects of Whole-Body HIIT and Moderate Continuous Exercise on Immune Function
This randomized controlled trial aimed to investigate the effects of a 12-week Whole-Body High-Intensity Interval Training (WB-HIIT) program compared with Moderate-Intensity Continuous Training (MICT) on immune function in…
- Trial name
- WBHIIT-IMM (NCT07618455)
- Testing
- Whole-Body High-Intensity Interval Training (WB-HIIT), Moderate-Intensity Continuous Training (MICT)
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Bitlis Eren University
Psoriasis
Pathogenesis of Periodontal Disease in Individuals With Psoriasis
The aim of this study is to evaluate the levels of Th17 cell-associated cytokines (IL-17, IL-21, IL-23) and the salivary stress biomarkers cortisol, dehydroepiandrosterone, and Chromogranin A in the pathogenesis of periodontal…
- Trial name
- NCT07158125
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Recep Tayyip Erdogan University Training and Research Hospital
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