Clinical trials: Cortisol
Root Canal Obturation
Endodontic Post-operative Pain Evaluation of Patients After Using Endomethasone N or Endomethasone SP (EndoPOP)
The study is a post-marketing performance and safety study, designed as a comparative, prospective, multicenter, simple-blind, randomized clinical trial.
- Trial name
- EndoPOP (NCT04885686)
- Testing
- Endomethasone N RCS, Endomethasone SP RCS
- Where
- 15 sites in France
- Volunteers
- 300 people
- Sponsor
- Septodont
Stress Psychological, Stress Physiological
Relaxation-Response-based Mental Health Promotion - Open and Calm 2013
The purpose of the study is to investigate health-promoting and stress-reducing psychological, physiological and hormonal effects of a 9-week meditation-based course in personal health and to examine potential baseline factors…
- Conditions
- Stress Psychological, Stress Physiological, Quality of Life
- Trial name
- RR-MHP OC13 (NCT02140307)
- Testing
- Relaxation Response-based Mental Health Promotion (RR-MHP)
- Where
- Denmark
- Volunteers
- 72 people
- Sponsor
- Steen G Hasselbalch
Depression
Depression, Adversity, and Stress Hormones (DASH) Study
The stress-related hormone cortisol has been studied in depression for decades. However, relatively little is known about the role of cortisol in psychological features of depression.
- Trial name
- DASH (NCT03195933)
- Testing
- Cortisol
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Hypoxic-Ischemic Encephalopathy, Asphyxia
Hydrocortisone Treatment In Systemic Low Blood Pressure During Hypothermia in Asphyxiated Newborns
This is a prospective, randomized, double-blind, placebo controlled, single center study to compare low dose hydrocortisone vs placebo in systemic low blood pressure during hypothermia treatment in asphyxiated newborns.
- Trial name
- CORTISoL (NCT02700828)
- Testing
- Hydrocortisone
- Where
- Hungary
- Volunteers
- 32 people
- Sponsor
- Semmelweis University
Combined Oral Contraceptive Cessation
CBG Normalization After Discontinuation of COC's
In this study, the investigators aim to examine after which duration corticosteroid-binding globulin (CBG) and total cortisol concentrations return to normal after cessation of the combined oral contraceptive pill in healthy…
- Trial name
- NCT06802211
- Where
- Netherlands
- Volunteers
- 24 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Stress
Effects of Stress on Observers and Their Subsequent Performance During High Fidelity Simulation-based Training.
This randomized controlled trial aims to determine if the stress response and performance of trainees who are observers in simulation training is similar to trainees who are actively participating in simulation training in the…
- Trial name
- NCT02211378
- Testing
- Observer, Hotseat
- Where
- Singapore
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- KK Women's and Children's Hospital
Shock, Septic, Critically Ill
The Vitamin C, Hydrocortisone and Thiamine in Patients With Septic Shock Trial
Sepsis has been characterised as a dysregulated host response to infection. Adjunctive therapies targeting the inflammatory cascade are being increasingly explored, although to date, have failed to demonstrate consistent benefit…
- Conditions
- Shock, Septic, Critically Ill, Vasoplegic Syndrome, Sepsis
- Trial name
- VITAMINS (NCT03333278)
- Testing
- Vitamin C, Thiamine, Hydrocortisone,
- Where
- 8 sites in Australia, Brazil and 1 more
- Volunteers
- 216 people
- Sponsor
- Australian and New Zealand Intensive Care Research Centre
Customized Healing Abutment Bone Grafts Connective Tissue Graft Immediate Implant Placement
Midfacial Gingival Margin Changes Following Immediate Implants.
Dimensional changes, including the loss of labial soft tissues and midfacial gingival recession, seem to be inevitable following immediate placement.
- Trial name
- NCT05975515
- Testing
- Connective tissue graft /Bone graft/ Customized HA
- Where
- Egypt
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Cairo University
Resistance Training, Immune System
Minimal-Dose Resistance Training for Improving sIgA and Cortisol
Whereas the role of endurance training on immune function has been widely studied, little is known about the role of resistance training (RT).
- Trial name
- sIgA (NCT05221996)
- Testing
- Resistance training
- Where
- Spain
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Universidad Francisco de Vitoria
Heroin Dependence, Opioid-Related Disorders
Studies of Opioid Seeking Behavior: Yohimbine and Hydrocortisone Effects
This research deals with behaviors that are part of opioid dependence. The purpose is to study the extent to which stress and other factors, including money and amount of work effort, affect opioid choice.
- Trial name
- YHO (NCT01536925)
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Wayne State University
Infant, Newborn, Infant, Small for Gestational Age
Hydrocortisone for BPD
The Hydrocortisone and Extubation study will test the safety and efficacy of a 10 day course of hydrocortisone for infants who are less than 30 weeks estimated gestational age and who are intubated at 14-28 days of life.
- Conditions
- Infant, Newborn, Infant, Small for Gestational Age, Infant, Very Low Birth Weight, Infant, Premature
- Trial name
- NCT01353313
- Testing
- Hydrocortisone
- Where
- 20 sites in United States
- Volunteers
- 800 people
- Sponsor
- NICHD Neonatal Research Network
Pregnancy
Epigenetic and Cortisol Level Reflections of Maternal Stress During Pregnancy
The aim of this study is to evaluate the effects of stress management and epigenetic awareness training provided in prenatal classes on maternal stress levels, cortisol levels, and epigenetic awareness.
- Trial name
- Maternal Stres (NCT07764380)
- Testing
- Maternal Epigenetics Training Module
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Kahramanmaras Sutcu Imam University
Molar Incisor Hypomineralization
Salivary Cortisol Levels in Children With Molar Incisor Hypomineralization
Molar incisor hypomineralization (MIH) is a developmental condition that affects the enamel of permanent molars and incisors in children and may cause tooth sensitivity, discomfort, and difficulties during dental treatment.
- Trial name
- NCT07389148
- Where
- Turkey (Türkiye)
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- Lokman Hekim University
Depressive Disorder and Anxiety Disorders
To Investigate Effects GSK561679 on Part of the Body's System That Controls the Balance of Many of the Hormones.
A study to investigate the effects GSK561679 on part of the body's system that controls the balance of many of the hormones (including cortisol).
- Trial name
- NCT00426608
- Testing
- metyrapone, alprazolam, GSK561679
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Halitosis, Periodontal Health
Effects of Green Tea Mouthwash on Halitosis, Periodontal Health, and Stress in Orthodontic Patients
This randomized, double-blind, four-arm clinical trial evaluates the effects of green tea mouthwash on halitosis, periodontal health, salivary stress biomarkers, and oxidative stress in patients undergoing fixed orthodontic…
- Conditions
- Halitosis, Periodontal Health, Orthodontic Treatment
- Trial name
- NCT07829224
- Testing
- Green Tea Mouthwash A, Green Tea Mouthwash B, Fluoride Mouthwash
- Where
- Iraq
- Volunteers
- 100 people
- Sponsor
- Universiti Sains Malaysia
Chronic Kidney Disease, Hemodialysis
Vibration Massage, Static Stretching Exercise, Intradialytic Muscle Cramps and Stress
Chronic kidney disease (CKD) is characterised by kidney damage that persists for 3 months or longer or an estimated glomerular filtration rate (eGFR) below 60 mL/min/1.73 m² and is assessed in 6 categories.
- Conditions
- Chronic Kidney Disease, Hemodialysis, Stress
- Trial name
- NCT06759376
- Testing
- Vibration massage, Static stretching exercise, Usual Care
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Figen Akay
Child Behavior Problem
Hair Cortisol and Symptoms in Children With Psychopathology During CBT
This study aims to examine the relationship between hair cortisol concentration and behavior and sleep disturbance symptoms in children with psychiatric disorders.
- Trial name
- NCT06274424
- Testing
- The Friends Program
- Volunteers
- 100 people
- Sponsor
- Helsinki University Central Hospital
Stress, Psychological, Physiological
Effects of Yoga on Objective and Self-reported Health Indicators Among Female and Male Individuals
The purpose of this study is to determine whether inversions (specific yoga postures in which the heart is higher than the head) and other dynamic and static yoga postures affect heart rate variability, oxygen uptake, blood…
- Trial name
- NCT01305096
- Testing
- Yoga intervention
- Where
- Sweden
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Temporomandibular Joint Disorder
Salivary Cortisol As a Biomarker in Patients with Temporomandibular Disorder
t is recognized that cortisol, a hormone produced by the adrenal glands, is a marker that is elevated in patients with psychological disorders, particularly anxiety.
- Trial name
- NCT06874868
- Where
- Portugal
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Coimbra
Chronic Obstructive Pulmonary Disease (COPD)
Comparing Hydrocortisone and Prednisolone for Acute Exacerbation of Chronic Obstructive Pulmonary Disease (AECOPD)
The goal of this cluster randomized controlled trial is to determine the optimal treatment for Acute Exacerbation of Chronic Obstructive Pulmonary Disease.
- Trial name
- NCT06892210
- Testing
- Methylprednisolone (drug), Hydrocortisone
- Where
- 14 sites in Denmark
- Volunteers
- 2,000 people
- Sponsor
- Copenhagen Respiratory Research
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