Clinical trials: Cosmetic
Facial Rhytides, Glabellar Frown Lines
Safety and Efficacy Study of Botulinum Toxin Type A for the Treatment of Forehead and Frown Lines
This study evaluated the safety and efficacy of botulinum toxin Type A compared to placebo for the treatment of forehead lines (facial rhytides) when also administered to frown lines (glabellar rhytides).
- Trial name
- NCT01391299
- Testing
- botulinum toxin Type A, Normal Saline
- Where
- Canada
- Volunteers
- 175 people
- Sponsor
- Allergan
Vaginal Flora Imbalance
Stryphnodendron Adstringens Intimate Soap
This is a single-centre, single-blind, non-comparative clinical trial to assess the safety of the investigational product through clinical probability assessment.
- Trial name
- NCT06085898
- Testing
- Stryphnodendron Adstringens 3% - once daily post bath
- Where
- Brazil
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Biolab Sanus Farmaceutica
Aesthetic, Cosmetic
The Effect of the Combination of Cleanser and Moisturizer Product K
This study is conducted to evaluate the effectiveness of product K cleanser and moisturizer when use in combination for skin rejuvenation.
- Conditions
- Aesthetic, Cosmetic, Healthy
- Trial name
- NCT05694429
- Testing
- Product K cleanser and moisturizer
- Where
- Malaysia
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- USMARI Research & Innovation Centre
Skin Pigmentation, Healthy Volunteers
Efficacy of Cosmetic Products in Preventing Pigmentation Induced by High Energy Visible Light (HEVL) [400-450nm]
The goal of this double-blind, randomized clinical trial is to evaluate the efficacy of anti-pigmentation cosmetic products in preventing skin pigmentation induced by High Energy Visible Light (HEVL) [400-450nm] in healthy…
- Conditions
- Skin Pigmentation, Healthy Volunteers, Hyperpigmentation
- Trial name
- NCT07537595
- Testing
- Treated and exposed zones (cosmetic topical products applied), Untreated and exposed zone (no product applied)
- Where
- Romania
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Cosmetique Active International
Erythema, Sun Damaged Skin
Efficacy Study of a Novel Skin Health Product to Reduce an UVB Induced Erythema
The aim of this study is to determine the erythema-reducing efficacy of a test product in two concentrations on a light sunburn induced by a sun simulator compared to an untreated control and a placebo product.
- Conditions
- Erythema, Sun Damaged Skin, Skin Inflammation
- Trial name
- NCT05300542
- Testing
- Topical Cream with 0.5% Active, Topical Cream with 1% Active
- Where
- Germany
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Amazentis SA
Wrinkles, Scars
Pilot Evaluation of the Cynosure Potenza™ System for Treatment of Cosmetic Dermatologic Skin Conditions
The primary objective of this pilot study is exploratory investigation evaluating the Potenza microneedle fractional radiofrequency (RF) device and may be used in combination with the Icon intense pulsed light (IPL) device.
- Conditions
- Wrinkles, Scars, Stretch Marks, Pigmentation
- Trial name
- NCT05847530
- Testing
- Potenza, Icon
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Cynosure, Inc.
Healthy
Safety and Efficacy of Facial Cleanser
This study is conducted to evaluate the safety and effectiveness of facial cleanser X containing combination of olive oil, virgin coconut oil, butylene glycol and hyaluronic acid on skin hydration and skin elasticity.
- Trial name
- NCT05691413
- Testing
- Other: Product X facial cleanser
- Where
- Malaysia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- USMARI Research & Innovation Centre
Atopic Dermatitis
Evaluation and Comparison of 2 Cosmetic Investigational Products in Adults With Atopic Dermatitis
The study consists in the application of 2 investigational products (one group per investigational product) under normal conditions of use, in adult participants with Atopic Dermatitis.
- Trial name
- NCT03632174
- Testing
- Topical Ointment with L. reuteri, Topical Ointment without L. reuteri
- Where
- South Africa
- Volunteers
- 36 people
- Sponsor
- BioGaia AB
Skin Aging of Face and Hands, Facial Wrinkles - Rough Texture - Hyperpigmentation
DMAE Oleate for Facial Skin Firmness and Fine Lines in Healthy Adults
This single-arm, cosmetic study will evaluate the efficacy of topical DMAE Oleate on facial skin firmness and lines/wrinkles in healthy adults.
- Conditions
- Skin Aging of Face and Hands, Facial Wrinkles - Rough Texture - Hyperpigmentation, Skin Laxity
- Trial name
- NCT07255560
- Testing
- Topical DMAE Oleate
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Bionos Biotech S.L.
Tooth Color
Evaluation of the Whitening Effect in Subjects After Professional Tooth Cleaning Procedure
The goal of this study is to learn if the toothpaste works to maintain effect of the professional tooth cleaning in adults. It will also learn about the safety of the product.
- Trial name
- NCT07438990
- Testing
- Whitening toothpaste, Regular toothpaste
- Where
- Spain
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Lacer S.A.
Breast Cancer
Using the Conture® Multi-Lumen Balloon to Deliver Accelerated Partial Breast Brachytherapy
This multiple site, prospective, non-randomized study has been designed to compile information on the efficacy of the Contura™ MLB in delivering APBI in appropriately selected patients through evaluation of dosimetric success as…
- Trial name
- NCT00699101
- Testing
- Conture Multi-Lumen Balloon
- Where
- United States
- Volunteers
- 342 people
- Sponsor
- SenoRx, Inc.
Acne
A Comparative Study of Cosmetic Product in Subjects With Facial Acne During an Associated-treatment Phase Followed by a Maintenance Phase
In this study, we are interested in the global benefit of the tested product as complementary care to a topical medical treatment during a 3 month-associated treatment phase followed by a 3 month-maintenance phase, compared to a…
- Trial name
- NCT06716398
- Testing
- Test product, Comparator product
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- Pierre Fabre Dermo Cosmetique
Skin Care
To Assess the Cutaneous Irritation and Sensitization Potential of a Cosmetic Facial Product Using a Human Repeat Insult Patch Test (HRIPT) in Healthy Participants
The objective of this clinical study is to assess the irritation and sensitisation potential of a cosmetic test product after repeated semi-occlusive patch applications to healthy human participants by following a conventional…
- Trial name
- NCT03175562
- Testing
- Facial micellar cleanser, Saline Solution: Sodium Chloride (NaCl; 0.9%)
- Where
- Brazil
- Volunteers
- 272 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Sunscreening Agents
Determination of the Sun Protection Factor (SPF) of a Cosmetic Daily De-fence Skin Cream
The purpose of this study is to determine the SPF of the test product according to the International Standards Organization (ISO) 24444:2010 methodology (In vivo determination of the SPF).
- Trial name
- NCT03136107
- Testing
- Physiogel Daily Defence Protective Day Cream Light, ISO 24444:2010 P3 Standard Sunscreen
- Where
- Germany
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Erythema, Skin Recovery
A Study to Gain Information How Well Dexpanthenol Derma Cream Helps the Face Skin to Recover After Cosmetic Lasering
In this study, researchers want to learn more about the effect of dexpanthenol cream on skin recovery and reduction of skin rash after a dermatological procedure (ablative laser) on the face for treatment of fine wrinkles, scars…
- Trial name
- NCT03852563
- Testing
- BAY207543 (Bepanthol), Semisolid vaseline
- Where
- Brazil
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Bayer
Skin Brightening
The Effect of Cosmetic Products on Skin Brightening
This is a single centre, single cell, blinded study designed to evaluate the effect of 5 cosmetic products on skin brightening, skin hydration and skin barrier function of the volar forearm after controlled UV exposure as…
- Trial name
- NCT06899321
- Testing
- Cosmetic product M68, Cosmetic product Z15, Cosmetic product R52
- Where
- India
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Unilever R&D
Cosmetic Effect
Quantitative Study of New Limbal Ring Prototypes
The study is designed to test five new soft contact lens color pattern variants to determine whether the test lens makes the wearers eyes look bigger, more defined or enhances their overall appearance.
- Trial name
- NCT02173535
- Testing
- etafilcon test contact lens Variant AP, etafilcon test contact lens Variant JG, etafilcon test contact lens Variant CS
- Where
- Hong Kong
- Volunteers
- 257 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Acne
EVALUATION OF THE EFFICACY OF COSMETIC PRODUCT IN ADULTS SUBJECTS WITH MILD TO MODERATE ACNE
EVALUATION OF THE EFFICACY OF COSMETIC PRODUCT IN ADULTS SUBJECTS WITH MILD TO MODERATE ACNE. USE TEST UNDER DERMATOLOGICAL CONTROL. THE STUDY CONDUCTED IN POLAND AND MAURITIUS
- Trial name
- NCT07107854
- Testing
- cosmetic: EFFACLAR ULTRA CONCENTRATED SERUM
- Where
- Poland
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Cosmetique Active International
Healthy
Re-epithelialization Efficacy Evaluation of Cosmetic Product RV1551P vs Non-treated Forearm of Healthy Adult Women
The aim of this study was to evaluate the impact of the product RV1551P GB3224 on skin microbiota during wound healing process, based on swab samples collected from lesion areas using an epidermally ablated skin model of erbium…
- Trial name
- NCT06387277
- Testing
- RV1551P GB3224
- Where
- France
- Volunteers
- 21 people
- Sponsor
- Pierre Fabre Dermo Cosmetique
Facial Photodamage
Study to Evaluate Efficacy and Tolerability of Two Topical Regimens in Subjects With Moderate to Severe Facial Photodamage Who Have Received Cosmetic Injections
This study will assess the efficacy and tolerability of two topical regimens (containing cosmetic human fibroblast-derived, physiologically-balanced growth factor combination products (HULK and TNS Essential Serum)
- Trial name
- NCT03559972
- Testing
- on-label facial injection
- Where
- 2 sites in United States
- Volunteers
- 40 people
- Sponsor
- Allergan