Clinical trials: Cosmetic Outcome
Suture Dermatologic, Surgery
Comparison of Cosmetic Outcomes of Straight Line and W-plasty Techniques for Linear Wound Closure
The purpose of this study is to compare the cosmetic outcome of traditional straight-line (SL) linear closure to that of W plasty (a type of geometric broken-line cutaneous closure technique) for closure of post-auricular wounds…
- Conditions
- Suture Dermatologic, Surgery, Cosmetic Outcome
- Trial name
- NCT05074199
- Testing
- W-plasty/Linear closure
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of California, Davis
Cutaneous Leishmaniasis, Scar
Cosmetic Outcome of Leishmaniasis Scar After WR279396 Application
Primary Objectives: Assess whether CL (caused by Leishmaniasis major) lesions treated with WR279396 improved the cosmetic outcome compared with no treatment (natural healing)
- Trial name
- SCAR (NCT00490230)
- Testing
- WR 279396
- Where
- Tunisia
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- U.S. Army Medical Research and Development Command
Recurrent Breast Carcinoma, Ipsilateral Recurrence
Preoperative Partial Breast Reirradiation and Repeat Breast-conserving Surgery in Patients With Recurrent Breast Cancer: the REPEAT Trial
Over the past decades, interest in second breast-conserving therapy (BCT) has increased due to, among others, advancements in radiotherapy techniques.
- Trial name
- REPEAT (NCT06640881)
- Testing
- ablative single-dose PBI
- Where
- Netherlands
- Volunteers
- 25 people
- Sponsor
- Amsterdam UMC, location VUmc
Suture, Complication, Wound
Split Scar Study to Assess Cosmetic Outcome From Differing Suture Spacing
The investigators wish to determine how suture spacing (5 mm vs. 10 mm) affects cosmetic outcome and development of "train tracking" in wounds.
- Conditions
- Suture, Complication, Wound, Wound Complication, Wound Dehiscence
- Trial name
- SFD (NCT03284983)
- Testing
- Suture spacing for wound closure
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Silver Falls Dermatology
Wound Healing Cosmetic Result
Clinical Study Into the Cosmetic Results of Leukosan Adhesive
This clinical study aims to assess whether the benefits of using Leukosan Adhesive on trocar incisions are greater or equivalent to those provided by the standard therapy of transcutaneous sutures.
- Trial name
- NCT02179723
- Testing
- Leukosan Adhesive, Transcutaneous suture
- Where
- Germany
- Volunteers
- 77 people
- Sponsor
- Dr. Stephanie Krause
Caesarean Delivery
Subcutaneous Adaption and Cosmetic Outcome Following Caesarean Delivery
This is a double blinded randomized study investigating if subcutaneous adaption has an impact on cosmetic outcome after Caesarean delivery.
- Trial name
- NCT01542346
- Testing
- subcutaneous adaption
- Where
- Austria
- Volunteers
- 116 people
- Sponsor
- Klinikum Klagenfurt am Wörthersee
Breast Fibrosis, Breast Cancer
An Integrated Optimization of Surgery and Radiotherapy Techniques to Improve Cosmetic Outcome and Quality of Life in Breast Conserving Therapy for Breast Cancer Patients (STARLINGS Study)
To assess the role of different combinations of (oncoplastic) surgery and radiotherapy techniques as risk factors for moderate to severe fibrosis and for moderate to poor cosmetic outcome.
- Conditions
- Breast Fibrosis, Breast Cancer, Breast Cancer Female, Breast Neoplasms
- Trial name
- STARLINGS (NCT05263362)
- Testing
- no intervention
- Where
- 4 sites in Netherlands
- Volunteers
- 775 people
- Sponsor
- Erasmus Medical Center
Eyelid Laceration
Cosmetic Outcome Study of Lid Laceration Repair With Suture Versus Tissue Adhesive
This project is a randomized, controlled trial investigating wound cosmetic appearance after repair of traumatic lid lacerations with three different approaches to skin closure: absorbable sutures, non-absorbable sutures, and…
- Trial name
- NCT01918059
- Testing
- Tissue Adhesive skin closure, Absorbable suture skin closure, Non-absorbable suture skin closure
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- The University of Texas Health Science Center, Houston
Successful Surgical Procedure, Operative Time
LESS Surgery Versus Conventional Multiport Laparoscopy in Ovarian Drilling
laparoendoscopic single-site surgery is compared to conventional multi-port laparoscopy for polycystic ovary syndrome in infertile women undergoing ovarian drilling as regards successful surgical procedure with less side effects
- Conditions
- Successful Surgical Procedure, Operative Time, Cosmetic Outcome, Intra- and Post- Operative Complications
- Trial name
- NCT03206892
- Testing
- laparoscopic ovarian drilling
- Where
- Egypt
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Ain Shams Maternity Hospital
Breast Cancer
Ten Fraction Adjuvant Hypofractionated Radiotherapy in Node Positive Breast Cancer
Post-operative loco-regional (LR) hypofractionated radiotherapy (Hypo-RT) is an attractive approach in locally advanced breast cancer (LABC).
- Trial name
- HIPOMAMMLINF (NCT04792346)
- Testing
- breast/chest wall radiotherapy
- Where
- Italy
- Volunteers
- 61 people
- Sponsor
- Regina Elena Cancer Institute
Hypertrophic Scar
Comparison of Cosmetic and Functional Outcome of Silicone Sheeting and Micro-needling on Hypertrophic Scars
Hypertrophic scars and keloids are frequently encountered in plastic surgery OPD. due to any reason, the normal wound healing is impaired, hypertrophic scars or keloids occur. These are thickened, wide and raised scars.
- Trial name
- NCT05108272
- Testing
- Microneedling, Percutaneous Collagen Induction
- Where
- 2 sites in Pakistan
- Volunteers
- 80 people
- Sponsor
- Foundation University Islamabad
Skin Tumour, Surgery
Intracutaneous Versus Transcutaneous Sutures in the Face (IC vs TC Sutures)
Rationale: Skin cancer is common in Caucasians and often exists on sun-exposed areas, such as the face. Treatment of choice is mostly excision and result in an irreversible scar.
- Trial name
- NCT02125058
- Testing
- Transcutaneous sutures, Intracutaneous sutures
- Where
- 3 sites in Netherlands
- Volunteers
- 142 people
- Sponsor
- Maastricht University Medical Center
Radiotherapy Side Effect
SMC Radiation Oncology Breast Cancer Cohort Study
The goal of this observational study is to learn about toxicities and cosmetic outcomes in breast cancer patients treated with hypofractionated radiotherapy.
- Trial name
- RASCO (NCT05775757)
- Testing
- Hypofractionated radiation therapy
- Where
- South Korea
- Volunteers
- 500 people
- Sponsor
- Samsung Medical Center
Breast Cancer
RAPID: Randomized Trial of Accelerated Partial Breast Irradiation
To determine if Accelerated Partial Breast Irradiation, using 3D CRT, is as effective as Whole Breast Irradiation following breast conserving surgery in women with an new histological diagnosis of ductal carcinoma in situ only or…
- Trial name
- NCT00282035
- Testing
- APBI utilizing 3D-CRT radiation, Whole breast irradiation
- Where
- 33 sites in Australia, Canada and 1 more
- Volunteers
- 2,135 people
- Sponsor
- Ontario Clinical Oncology Group (OCOG)
Thyroidectomy, Distress
Postoperative Distress and Cosmetic Outcomes After Open Versus Robotic Thyroidectomy
Robotic assistance during thyroid surgery has been utilized clinically in Korea since late 2007. Robotic thyroidectomy has also been validated for surgical management of the thyroid gland.
- Conditions
- Thyroidectomy, Distress, Surgery
- Trial name
- Robot1 (NCT01075269)
- Where
- South Korea
- Volunteers
- 84 people
- Sponsor
- Korean Association of Endocrine Surgeons
Breast Cancer
Conventional Versus Hypofractionated Radiotherapy in Node Positive Breast Cancer
Breast cancer patients operated with modified radical mastectomy or breast conservative surgery will be randomized for either adjuvant conventional radiotherapy versus hypofractionated radiotherapy for chest wall and axilla or…
- Trial name
- NCT02690636
- Testing
- radiotherapy
- Where
- Egypt
- Volunteers
- 500 people
- Sponsor
- Ain Shams University
Breast Neoplasm Female, Radiotherapy
A Randomized Trial of Five Fraction Partial Breast Irradiation (RAPID2)
The primary objective of this study is to determine in women with node negative BC ≤3cm in size, if PBI compared to WBI, both given once-a-day over 1 week following BCS, is non-inferior for LR and reduces adverse cosmesis.
- Conditions
- Breast Neoplasm Female, Radiotherapy, Cosmetic Outcome
- Trial name
- NCT05417516
- Testing
- Whole Breast Irradiation (WBI), Partial Breast Irradiation (PBI)
- Where
- 31 sites in Australia, Canada
- Volunteers
- 910 people
- Sponsor
- Ontario Clinical Oncology Group (OCOG)
Suture, Dermatologic Surgery
Aesthetic Outcome of Running Cuticular Suture Distance (2mm vs 5mm)
It is standard teaching that the top layer of sutures should be placed 3-5mm from the wound edge. However, there is lack of data regarding the most optimal placement of sutures from the wound edge for the best cosmetic outcome.
- Conditions
- Suture, Dermatologic Surgery, Scar, Cosmetic Outcome
- Trial name
- NCT04870008
- Testing
- Suture
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of California, Davis
Breast Cancer
Use of the Contura™ Catheter to Deliver Accelerated Partial Breast Irradiation to "Low-risk" Breast Cancer Patients
The purpose of this national, multi-site study is to determine the safety and effectiveness of the Contura catheter in breast cancer patients undergoing accelerated partial breast irradiation.
- Trial name
- NCT00882596
- Testing
- Accelerated partial breast irradiation
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Cancer Center of Irvine
Breast Image Scale Index for Self Esteem Evaluation, Breast Symmetry Index
Prospective Non-randomized Evaluation of Oncoplastic Surgery
Breast conserving therapy (BCT) is the standard treatment for intraductal or invasive breast cancer patients. However cosmetic results, e.g. symmetry and nipple displacement, are sometimes poor reducing the quality of life.
- Conditions
- Breast Image Scale Index for Self Esteem Evaluation, Breast Symmetry Index, Quality of Life, Morbidity
- Trial name
- iTOP (NCT01396993)
- Testing
- Breast Surgery
- Where
- Austria
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna