Clinical trials: Cosmetic Outcome
Burns
A Randomized Comparison Study of Aquacel Ag and Glucan II as Donor Site Dressings
The research will be looking at patient outcomes for healing of donor sites after a split-thickness skin graft procedure for a burn or skin tissue loss.
- Trial name
- NCT00581217
- Testing
- Aquacel Ag, Glucan II
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of California, Irvine
Wound Complication, Surgical Wound Infection
Cosmetic Outcome of Electrocautery, Scalpel and PEAK PlasmaBlade for Surgical Breast Incisions
This study will compare the cosmetic scar result from the use of scalpel, electrocautery, and pulsed electron avalanche knife (PEAK) PlasmaBlade (PPB) for the initial skin incision for total mastectomy procedures without…
- Conditions
- Wound Complication, Surgical Wound Infection, Post-operative Pain, Postoperative Complications
- Trial name
- SCPPB (NCT06191159)
- Testing
- Scalpel and standard electrocautery or PEAK PlasmaBlade, PEAK PlasmaBlade, Standard Electrocautery
- Where
- Canada
- Volunteers
- 186 people
- Sponsor
- University of British Columbia
Breast Cancer
Coated VICRYL* Plus Suture Compared to Chinese Silk in Scheduled Breast Cancer Surgery
This is a 90-day study to evaluate cosmetic outcome and Surgical Site Infection in approximately 100 patients from 6 centers in China undergoing scheduled modified radical mastectomy for breast cancer.
- Trial name
- NCT00768222
- Testing
- silk suture, VICRYL* Plus suture
- Where
- 6 sites in China
- Volunteers
- 101 people
- Sponsor
- Ethicon, Inc.
To Prevent Scar Formation for Patients Underwent Surgery
The Effect of Centella Asiatica Cream on Scar Tenderness Who Underwent Open Carpal Tunnel Release Surgery
The centella asiatica cream applied to the wrist after the CTR surgery was found to be beneficial in preventing the scar tenderness in the thenar and hypothenar regions of the hand.
- Trial name
- NCT05017467
- Testing
- undefinedCentella Asiatica Extract
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- Mustafa Balevi,MD
Breast Cancer
Cosmetic Result/Toxicity in Post-Mastectomy Immediate Reconstruction Expander+RT
This research study is being done to carefully evaluate the effect of giving radiation therapy after temporary breast reconstruction.
- Trial name
- NCT01664091
- Testing
- post-mastectomy radiation therapy (PMRT), tissue expander (TE), acellular dermal matrix (ADM)
- Where
- 2 sites in United States
- Volunteers
- 32 people
- Sponsor
- Dana-Farber Cancer Institute
Breast Cancer, Breast Reconstruction After Mastectomy
Study on the Cosmetic Outcome and Safety Evaluation of 3D Printed Biodegradable Biological Mesh for One-Stage Breast Reconstruction After Radical Mastectomy
Primary objective of this trial: To evaluate the clinical performance (aesthetic outcome and quality of life) and safety of a 3D-printed biodegradable biological mesh in post-mastectomy immediate breast reconstruction.
- Conditions
- Breast Cancer, Breast Reconstruction After Mastectomy, 3D-Printed Biodegradable Biological Mesh
- Trial name
- NCT07365267
- Testing
- Implantation of a silicone breast prosthesis combined with a 3D-printed biodegradable mesh
- Where
- China
- Volunteers
- 25 people
- Sponsor
- Xijing Hospital
Surgery
Thyroid Cosmesis Study at St. Paul's Hospital, Vancouver BC
This study looks at the difference in surgical scar outcomes between two different surgical incision methods during thyroid surgery: scalpel vs electrocautery. Patients who are already scheduled for thyroid surgery with Dr.
- Trial name
- NCT02458989
- Testing
- Scalpel, Electrocautery
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Dr. Sam M. Wiseman
Scar, Skin Scarring
Scar Appearance After Postoperative Hydrocolloid Dressing Versus Standard Petrolatum Ointment
Patients will be randomized either to receive standard daily dressing or hydrocolloid dressing using a randomization generator. After closing the wound with the sutures,the scar will be covered by a hydrocolloid dressing, which…
- Conditions
- Scar, Skin Scarring, Skin Cancer, Wound Heal
- Trial name
- NCT05618912
- Testing
- Hydrocolloid dressing, Petrolatum jelly dressing
- Where
- United States
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- Indiana University
Cosmetic Outcome, Infection
Sutures Versus Glue in Laparoscopic Port Site Closure.
Cosmesis postoperatively is an important consideration for both patients and surgeons and consequently surgeons have become increasingly interested in replacing conventional sutures by means of adhesive bonds for the closure of…
- Conditions
- Cosmetic Outcome, Infection, Cost
- Trial name
- STILS (NCT03843866)
- Testing
- 4-0 Monocryl, Adhesive Glue
- Where
- Ireland
- Volunteers
- 200 people
- Sponsor
- St. James's Hospital, Ireland
Appendicitis
Wound Healing After Emergency Appendicectomy
The purpose of this trial is to compare two techniques of wound closure in open appendicectomies in adult patients: continuous, absorbable, intradermal suture and interrupted, non-absorbable sutures.
- Trial name
- NCT00913445
- Testing
- appendicectomy
- Where
- Finland
- Volunteers
- 200 people
- Sponsor
- Tampere University Hospital
Breast Cancer
Impact of 5-fraction Stereotactic Partial Breast Irradiation and Whole Breast Irradiation on Cosmetic Outcome and Patient-reported Outcomes in Early-stage Breast Cancer
This study aim to investigate the effect of 5-fraction stereotactic partial breast irradiation and whole breast irradiation on patient-reported outcomes, cosmetic outcome, and breast tissue fibrosis in early-stage breast cancer.
- Trial name
- NCT03568981
- Testing
- Partial breast irradiation, Whole breast irradiation
- Where
- South Korea
- Volunteers
- 200 people
- Sponsor
- Yonsei University
Breast Cancer
Using the Conture® Multi-Lumen Balloon to Deliver Accelerated Partial Breast Brachytherapy
This multiple site, prospective, non-randomized study has been designed to compile information on the efficacy of the Contura™ MLB in delivering APBI in appropriately selected patients through evaluation of dosimetric success as…
- Trial name
- NCT00699101
- Testing
- Conture Multi-Lumen Balloon
- Where
- United States
- Volunteers
- 342 people
- Sponsor
- SenoRx, Inc.
Breast Cancer
Single-dose Preoperative Partial Breast Irradiation in Low-risk Breast Cancer Patients
In this ABLATIVE-2 trial, low-risk breast cancer patients will be treated with MRI-guided single dose preoperative partial breast radiotherapy to assess the rate of pathologic complete response after an interval of six to twelve…
- Trial name
- ABLATIVE-2 (NCT05350722)
- Testing
- Single dose ablative radiotherapy
- Where
- 7 sites in Australia, Netherlands
- Volunteers
- 100 people
- Sponsor
- Amsterdam UMC, location VUmc
Bowen's Disease
Trial of Excision Versus Photodynamic Therapy in the Treatment of Bowen's Disease
The purpose of this study is to identify the most optimal therapy for Bowen's disease: excision versus Photodynamic therapy.
- Trial name
- NCT00472706
- Testing
- excision, Photodynamic therapy
- Volunteers
- 65 people
- Sponsor
- Catharina Ziekenhuis Eindhoven
Breast Cancer
Dose Optimization for Pulsed-dose-rate (PDR)/High-dose-rate (HDR) Brachytherapy Alone for Early Breast Cancer
Accelerated partial breast irradiation (APBI) leads to a equivalent local control rate with lower toxicity as external beam irradiation (EBI) after breast conserving surgery (BCS) in a highly selected subgroup of patients with…
- Trial name
- NCT01175694
- Testing
- Interstitial multicatheter brachytherapy
- Where
- Germany
- Volunteers
- 200 people
- Sponsor
- University Hospital Erlangen
Wound Closure Technique, Wound Dehiscence, Surgical
Comparison of Cosmetic Outcome and Patient Satisfaction Between Staples and Suture Technique for Wound Closure Following Upper Limb Surgeries
Surgical wound closure is an essential component of postoperative care that influences wound healing, infection rates, cosmetic appearance, and patient satisfaction.
- Trial name
- NCT07633977
- Testing
- Staples, Sutures
- Where
- Nepal
- Volunteers
- 80 people
- Sponsor
- Kathmandu University School of Medical Sciences
Breast Neoplasms
The Oncological Safety and Cosmetic Outcome of Areola Sparing Mastectomy : a Single Arm, Prospective, Cohort Study
To balance the oncological safety and cosmetic outcome is the basic principle of modern breast surgery. To preserve the nipple-areolar complex shows attractive cosmetic advantage but concerns regarding local recurrence make the…
- Trial name
- NCT03105570
- Testing
- Areola Sparing Mastectomy
- Where
- China
- Volunteers
- 145 people
- Sponsor
- Peking University People's Hospital