Clinical trials: Cost-Effectiveness
Breast Cancer
Laser Speckle Imaging During Breast Reconstruction
Around 3500 women a year have surgery to reconstruct a breast/s after cancer. Breast reconstruction can have a positive impact on their lives, but unfortunately 3 or 4 in 10 women have problems with healing after their operation.
- Trial name
- SIMBAR (NCT06523452)
- Testing
- Laser Speckle Imaging
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Royal Devon and Exeter NHS Foundation Trust
Chronic Obstructive Pulmonary Disease
Real-life Effectiveness and Cost-effectiveness of Qvar Versus FP and BDP in the Management of COPD
The objective of this study is to compare the effectiveness, cost-effectiveness and direct healthcare costs of managing chronic obstructive pulmonary disease (COPD) in primary care patients with evidence of COPD who either…
- Trial name
- QvarCOPD (NCT01141452)
- Testing
- Extra-fine hydrofluoroalkane beclomethasone MDI, Chlorofluorocarbon beclomethasone metered dose inhaler, Fluticasone propionate metred dose inhaler
- Where
- United Kingdom
- Volunteers
- 815,377 people
- Sponsor
- Research in Real-Life Ltd
Isolated Fever, Gastroenteritis Symptoms
The Effectiveness and Cost-effectiveness of Medical Advice Given by Telephone for Patients Calling for Primary Care
Telephone medical advice in general practice is expanding. The Cochrane Database concludes in 2008 that there is not enough data about its use regarding out-of-hours general practitioners workload, emergency department visits…
- Trial name
- CMTp (NCT02286245)
- Testing
- focused Telephonic Medical Advice, Usual practice
- Where
- France
- Volunteers
- 2,498 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Lung Cancer
Cost-effectiveness Evaluation of Robotic Surgery in the Removal of Lung Lesions in the ATS of Milan
The goal of this observational study is to compare cost-effectiveness of robotic surgery with open surgery and video-assisted thoracoscopy surgery (VATS) in adult patients, resident in the ATS of Milan area, operated for lung…
- Trial name
- NCT05674227
- Testing
- Robotic surgery, Video-assisted thoracoscopy, Open surgery
- Volunteers
- 5,400 people
- Sponsor
- Agenzia di Tutela della Salute della Città Metropolitana di Milano
Diabetes
Twelve -Month Study Observing How Insulin-naïve Patients With Type 2 Diabetes Mellitus Manage Diabetes Using Toujeo® After Oral Antidiabetic Drug Failure, the Side Effect of Toujeo®, and The Cost.
Primary Objective: Assess effectiveness of insulin glargine (U300) in achieving glycemic goal measured by hemoglobin A1c (HbA1c).
- Trial name
- ATOS (NCT03703869)
- Testing
- Insulin glargine (U300)
- Where
- 388 sites in Colombia, Egypt and 16 more
- Volunteers
- 4,589 people
- Sponsor
- Sanofi
Alcohol Consumption, Drug-Food Interaction
Online Education to Inform the Elderly About Age-related Alcohol Risks
This proposed Phase 2 The Small Business Innovation Research study is a randomized trial of the effectiveness of "A Toast to Health in Later Life!" a web-based patient educational program designed to prevent hazardous and harmful…
- Trial name
- NCT02952495
- Testing
- Online alcohol educational class
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Arlene Fink Associates
Pyeloplasty, Complications of Surgical Procedures or Medical Care
Cost-Effectiveness and Clinical Outcomes of Double J Stent Versus Percutaneous Feeding Tube Placement Following Open Pyeloplasty in Pediatric Patients: A Prospective Randomized Single-center Study
Open pyeloplasty is a common surgical intervention for pediatric patients with ureteropelvic junction obstruction. Post-operative management strategies, including the use of a double J stent and a percutaneous feeding tube, vary…
- Conditions
- Pyeloplasty, Complications of Surgical Procedures or Medical Care, Hospital Stay
- Trial name
- DJS (NCT06847841)
- Testing
- Double J Stent Placement, Percutaneous Feeding Tube Placement
- Where
- Pakistan
- Volunteers
- 140 people
- Sponsor
- Hayat Abad Medical Complex, Peshawar
Incontinence, Urinary Tract Infection
Effectiveness of the AI-Supporter in Reducing Urinary Tract Infections
The "AI Supporter," an intelligent excretion management robot, leverages artificial intelligence-based vision recognition to autonomously detect and cleanse affected areas, followed by drying and changing the diaper, thereby…
- Conditions
- Incontinence, Urinary Tract Infection, Incontinence-associated Dermatitis, Cost-effectiveness
- Trial name
- NCT06613503
- Testing
- AI-supporter
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- China Medical University Hospital
Postnatal Depression, Self Efficacy
Effectiveness of 'Supportive Parenting App' on Parental and Newborn Outcomes
The Supportive Parenting App is a theory-based perinatal educational intervention for couples administered through a mobile application.
- Conditions
- Postnatal Depression, Self Efficacy, Parent-Child Relations, Development, Child
- Trial name
- NCT04706442
- Testing
- Supportive Parenting Application
- Where
- Singapore
- Volunteers
- 398 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Scar
Comparison of Lasers in the Treatment of Scars
The purpose of this study is to compare the 1550-nm non-ablative Fraxel laser (referred to as Fraxel Laser in this application) to the ablative 10,600-nm carbon dioxide fractional laser (referred to as CO2 Laser in this…
- Trial name
- NCT02988622
- Testing
- Fraxel Laser, CO2 Laser
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Marta Hemmingson-Van Beek
Safety of Intervention, Efficacy of Intervention
Video-assisted Hyperthermic Pleural Chemoperfusion vs Talc Pleurodesis for Refractory Malignant Pleural Effusions.
Aim of this study is to compare two methods of pleurodesis for refractory malignant pleural effusions, in terms of safety and efficacy.
- Conditions
- Safety of Intervention, Efficacy of Intervention, Cost Effectiveness
- Trial name
- NCT01409551
- Testing
- VATS hyperthermic chemoperfusion, Bedside talc slurry pleurodesis
- Where
- Greece
- Volunteers
- 60 people
- Sponsor
- Theagenio Cancer Hospital
Femoral Fractures, Pelvic Fractures
Tactile Incentiviser Improves Partial Weight Bearing After Lower-Limb Surgery
Background: After lower-limb surgery, many patients are instructed to walk with only a fraction of their body weight on the operated leg (partial weight bearing).
- Conditions
- Femoral Fractures, Pelvic Fractures, Hip Fractures (ICD-10 72.01-72.2), Hip Arthroplasty
- Trial name
- NCT06989554
- Testing
- mechanical feedback insole, Standard physiotherapy without feedback device
- Where
- Italy
- Volunteers
- 34 people
- Sponsor
- Università degli Studi dell'Insubria
Stroke Sequelae
Telerehabilitation for Post-stroke Patients
In the last few years, there has been an increasing shift towards outpatients setting in the care of patients with stroke. Unfortunately, this led to a high percentage of discharged patients who did not receive an adequate amount…
- Trial name
- NCT04413240
- Testing
- Telerehabilitation, Conventional rehabilitation
- Where
- Italy
- Volunteers
- 90 people
- Sponsor
- Universita di Verona
Carotid Stenosis
CARMEDAS: Cost-Effectiveness Analysis of Imaging Strategies in Symptomatic Carotid Stenosis
PURPOSE: The purpose of this clinical trial is to study the cost-effectiveness ratios of diagnostic strategies for the imaging assessment of symptomatic carotid stenosis.
- Trial name
- NCT00131001
- Testing
- contrast-enhanced magnetic resonance angiography
- Where
- France
- Volunteers
- 300 people
- Sponsor
- Hospices Civils de Lyon
Malaria, Falciparum
Preventing Malaria During Pregnancy in Epidemic-prone Areas.
The purpose of this study is to compare the efficacy and cost-effectiveness of three alternative strategies for the prevention of malaria during pregnancy in an epidemic-prone area of low transmission in the East African…
- Trial name
- NCT00142207
- Testing
- Intermittent preventive treatment:sulphadoxine-pyrimethamine, Insecticide-treated mosquito bed net
- Where
- Uganda
- Volunteers
- 4,775 people
- Sponsor
- London School of Hygiene and Tropical Medicine
Asthma Intermittent, Uncontrolled
Εffectiveness of a Digital Social Intervention in Primary Care
The goal of this study is to deliver a definitive randomised controlled trial to measure the effectiveness and assess cost-effectiveness of a digital social intervention for patients with asthma, composed of promoting engagement…
- Trial name
- ADHOC (NCT06849245)
- Testing
- A digital social intervention by primary care clinicians
- Where
- 5 sites in United Kingdom
- Volunteers
- 600 people
- Sponsor
- Queen Mary University of London
Smoking Cessation
Effectiveness of Smoking-cessation Interventions for Urban Hospital Patients
The investigators plan to compare the effectiveness and cost effectiveness of an inpatient smoking cessation intervention for all smokers hospitalized at two urban public hospitals.
- Trial name
- NCT01363245
- Testing
- Telephone Counseling, Fax-to-quit
- Where
- 2 sites in United States
- Volunteers
- 1,618 people
- Sponsor
- NYU Langone Health
Sleep Apnea Syndrome
Management of Patients With Suspected of Sleep Apnea-hypopnea Syndrome From Primary Care
Obstructive sleep apnea syndrome (OSA) is characterized by the manifestation of excessive sleepiness secondary to repeated obstruction of the upper airway during sleep and cognitive-behavioral, respiratory, cardiac, metabolic or…
- Trial name
- GESAP (NCT02234765)
- Testing
- Primary Care-based management, Standard management
- Where
- Spain
- Volunteers
- 280 people
- Sponsor
- Sociedad Española de Neumología y Cirugía Torácica
Early Mobilization, Physiotherapy
Rehabilitation of Patients From the ICU to the Post-hospital Phase
Introduction: Advances in knowledge have contributed to the increase in the number of patients who survive prolonged hospitalization in an Intensive Care Unit (ICU), and, among them, critically ill patients who develop acute…
- Conditions
- Early Mobilization, Physiotherapy, Rehabilitation
- Trial name
- NCT06405529
- Testing
- Early and intensive mobilization protocol at the ICU and Rehabilitation post-hospital discharge
- Volunteers
- 206 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
PrEP, HIV Prevention
The Community PrEP Study to Assess the Acceptance of PrEP Delivered Through CBCT Platforms
The investigators aim to 1) speed up access to and delivery of PrEP to young women, and 2) compare interventions to support and maximize the prevention-effective use of PrEP.
- Conditions
- PrEP, HIV Prevention, Adolescence, Cost-effectiveness
- Trial name
- NCT03977181
- Testing
- Group-based Community Health Club, Individual-based Adherence Support
- Where
- South Africa
- Volunteers
- 480 people, healthy volunteers welcome
- Sponsor
- Foundation for Professional Development (Pty) Ltd
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